clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Whooping Cough D014917 6 associated lipids
Uveitis, Anterior D014606 11 associated lipids
Urticaria D014581 13 associated lipids
Urination Disorders D014555 9 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Urethritis D014526 9 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Ureteral Diseases D014515 3 associated lipids
Typhoid Fever D014435 2 associated lipids
Tuberculosis, Spinal D014399 1 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Tuberculosis, Ocular D014392 1 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Tuberculosis D014376 20 associated lipids
Tooth Discoloration D014075 7 associated lipids
Tenosynovitis D013717 3 associated lipids
Syphilis D013587 6 associated lipids
Synovitis D013585 15 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Stomach Ulcer D013276 75 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


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Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Heifets L et al. Capreomycin is active against non-replicating M. tuberculosis. 2005 Ann. Clin. Microbiol. Antimicrob. pmid:15804353
Gould SW et al. The need for continued monitoring of antibiotic resistance patterns in clinical isolates of Staphylococcus aureus from London and Malta. 2010 Ann. Clin. Microbiol. Antimicrob. pmid:20663145
Sethi S et al. Antibiotic activity of telithromycin and comparators against bacterial pathogens isolated from 3,043 patients with acute exacerbation of chronic bronchitis. 2005 Ann. Clin. Microbiol. Antimicrob. pmid:15755326
Sankar MM et al. In-vitro antimycobacterial drug susceptibility testing of non-tubercular mycobacteria by tetrazolium microplate assay. 2008 Ann. Clin. Microbiol. Antimicrob. pmid:18620572
Destura RV et al. Laboratory diagnosis and susceptibility profile of Helicobacter pylori infection in the Philippines. 2004 Ann. Clin. Microbiol. Antimicrob. pmid:15546485
Tanabe H et al. Vonoprazan-based triple therapy is non-inferior to susceptibility-guided proton pump inhibitor-based triple therapy for Helicobacter pylori eradication. 2018 Ann. Clin. Microbiol. Antimicrob. pmid:29950163
Akram FE et al. A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA). 2016 Ann. Clin. Microbiol. Antimicrob. pmid:27530257
Bago J et al. Antimicrobial resistance of H. pylori to the outcome of 10-days vs. 7-days Moxifloxacin based therapy for the eradication: a randomized controlled trial. 2010 Ann. Clin. Microbiol. Antimicrob. pmid:20398300
Chen J et al. Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene. 2018 Ann. Clin. Microbiol. Antimicrob. pmid:29562911
Seck A et al. Primary antibiotic resistance and associated mechanisms in Helicobacter pylori isolates from Senegalese patients. 2013 Ann. Clin. Microbiol. Antimicrob. pmid:23298145
Mohan S et al. Physician behaviour for antimicrobial prescribing for paediatric upper respiratory tract infections: a survey in general practice in Trinidad, West Indies. 2004 Ann. Clin. Microbiol. Antimicrob. pmid:15196306
Bolland MJ et al. Osteomalacia in an HIV-infected man receiving rifabutin, a cytochrome P450 enzyme inducer: a case report. 2008 Ann. Clin. Microbiol. Antimicrob. pmid:18226256
Korkmaz S et al. Unusual manifestations of acute Q fever: autoimmune hemolytic anemia and tubulointerstitial nephritis. 2012 Ann. Clin. Microbiol. Antimicrob. pmid:22607576
Valentini P et al. An uncommon presentation for a severe invasive infection due to methicillin-resistant Staphylococcus aureus clone USA300 in Italy: a case report. 2008 Ann. Clin. Microbiol. Antimicrob. pmid:18447939
Myers AL et al. Genetic commonality of macrolide-resistant group A beta hemolytic streptococcus pharyngeal strains. 2009 Ann. Clin. Microbiol. Antimicrob. pmid:19951439
Chen J and Raymond K Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor. 2006 Ann. Clin. Microbiol. Antimicrob. pmid:16480505
Roberts JC et al. Fatal necrotizing pneumonia due to a Panton-Valentine leukocidin positive community-associated methicillin-sensitive Staphylococcus aureus and Influenza co-infection: a case report. 2008 Ann. Clin. Microbiol. Antimicrob. pmid:18284686
Ribeiro ML et al. Mutations in the 23S rRNA gene are associated with clarithromycin resistance in Helicobacter pylori isolates in Brazil. 2003 Ann. Clin. Microbiol. Antimicrob. pmid:14633281
Jenkins SG et al. Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1-4. 2008 Ann. Clin. Microbiol. Antimicrob. pmid:18190701
Ben Mansour K et al. Primary resistance to clarithromycin, metronidazole and amoxicillin of Helicobacter pylori isolated from Tunisian patients with peptic ulcers and gastritis: a prospective multicentre study. 2010 Ann. Clin. Microbiol. Antimicrob. pmid:20707901
Anand TD et al. Superantigen profiles of emm and emm-like typeable and nontypeable pharyngeal streptococcal isolates of South India. 2012 Ann. Clin. Microbiol. Antimicrob. pmid:22296671
Tsumoto C et al. Long-term efficacy of Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura: 7-year follow-up prospective study. 2009 Ann. Hematol. pmid:19096845
Soler JA et al. H. pylori eradication does not reduce paraprotein levels in monoclonal gammopathy of unknown significance (MGUS): a prospective cohort study. 2009 Ann. Hematol. pmid:19159929
Kornacker M et al. Occurrence of sarcoidosis subsequent to chemotherapy for non-Hodgkin's lymphoma: report of two cases. 2002 Ann. Hematol. pmid:11907791
Kato H et al. Addition of clarithromycin to lenalidomide/low-dose dexamethasone was effective in a case of relapsed myeloma after long-term use of lenalidomide. 2013 Ann. Hematol. pmid:23625297
Bilgilier C et al. Prevalence of clarithromycin-resistant Helicobacter pylori strains in gastric mucosa-associated lymphoid tissue lymphoma patients. 2016 Ann. Hematol. pmid:27091350
Huang HC et al. Primary central nervous system diffuse large B cell lymphoma transformed from orbital mucosa-associated lymphoid tissue lymphoma: complete response to combined intrathecal and systemic rituximab. 2013 Ann. Hematol. pmid:23242476
Kim H et al. Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia. 2015 Ann. Hematol. pmid:25501820
Kobayashi T et al. The potential role of clarithromycin addition to lenalidomide and dexamethasone therapy (BiRd) in multiple myeloma. 2018 Ann. Hematol. pmid:29427183
Todo K et al. Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female. 2016 Ann. Hematol. pmid:26957356
Alpen B et al. Helicobacter pylori eradication therapy in gastric high grade non Hodgkin's lymphoma (NHL). 2001 Ann. Hematol. pmid:11757689
Tsutsumi Y et al. Randomized study of Helicobacter pylori eradication therapy and proton pump inhibitor monotherapy for idiopathic thrombocytopenic purpura. 2005 Ann. Hematol. pmid:16078036
Souto Filho JTD et al. Long-term complete remission of primary gastric plasmacytoma following endoscopic resection. 2017 Ann. Hematol. pmid:28315923
Musher DM Clarithromycin therapy for Mycobacterium avium complex bacteremia. 1995 Ann. Intern. Med. pmid:7778830
van der Meer JT and Danner SA Clarithromycin therapy for Mycobacterium avium complex bacteremia. 1995 Ann. Intern. Med. pmid:7778831
Patel AM et al. Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. 2013 Ann. Intern. Med. pmid:23778904
Steinman MA et al. Changing use of antibiotics in community-based outpatient practice, 1991-1999. 2003 Ann. Intern. Med. pmid:12667022
Chaisson RE et al. Clarithromycin therapy for bacteremic Mycobacterium avium complex disease. A randomized, double-blind, dose-ranging study in patients with AIDS. AIDS Clinical Trials Group Protocol 157 Study Team. 1994 Ann. Intern. Med. pmid:7978715
Goldberger M and Masur H Clarithromycin therapy for Mycobacterium avium complex disease in patients with AIDS: potential and problems. 1994 Ann. Intern. Med. pmid:7978725
Shafran SD et al. Successful discontinuation of therapy for disseminated Mycobacterium avium complex infection after effective antiretroviral therapy. 2002 Ann. Intern. Med. pmid:12416943
Vaira D et al. Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized trial. 2007 Ann. Intern. Med. pmid:17438314
Singh N and Yu VL Clarithromycin therapy for Mycobacterium avium complex bacteremia. 1995 Ann. Intern. Med. pmid:7632282
Wallace RJ et al. Clinical trial of clarithromycin for cutaneous (disseminated) infection due to Mycobacterium chelonae. 1993 Ann. Intern. Med. pmid:8357113
Neu HC New macrolide antibiotics: azithromycin and clarithromycin. 1992 Ann. Intern. Med. pmid:1310839
McMahon BJ et al. The relationship among previous antimicrobial use, antimicrobial resistance, and treatment outcomes for Helicobacter pylori infections. 2003 Ann. Intern. Med. pmid:13679322
Sjölund M et al. Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori. 2003 Ann. Intern. Med. pmid:13679325
Summaries for patients. Past antibiotic use affects resistance and outcomes of Helicobacter pylori infection. 2003 Ann. Intern. Med. pmid:13679344
Summaries for patients. Effects of antibiotic treatment for Helicobacter pylori on normal bowel bacteria. 2003 Ann. Intern. Med. pmid:13679347
Liviu L et al. Pancreatitis induced by clarithromycin. 1996 Ann. Intern. Med. pmid:8849171
Seow J and Chew FT Risk factors for Helicobacter pylori resistance. 2004 Ann. Intern. Med. pmid:15172911
Jafri NS et al. Meta-analysis: sequential therapy appears superior to standard therapy for Helicobacter pylori infection in patients naive to treatment. 2008 Ann. Intern. Med. pmid:18490667
Berk SL New macrolide antibiotics. 1992 Ann. Intern. Med. pmid:1386966
Ohkusa T et al. Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial. 1998 Ann. Intern. Med. pmid:9841603
Summaries for patients. Factors associated with Helicobacter pylori infections in the United States that are resistant to usual antibiotics. 2002 Ann. Intern. Med. pmid:11797613
De Francesco V et al. Clarithromycin-resistant genotypes and eradication of Helicobacter pylori. 2006 Ann. Intern. Med. pmid:16418408
Meyer JM et al. Risk factors for Helicobacter pylori resistance in the United States: the surveillance of H. pylori antimicrobial resistance partnership (SHARP) study, 1993-1999. 2002 Ann. Intern. Med. pmid:11777360
Trivedi S et al. Clarithromycin and digoxin toxicity. 1998 Ann. Intern. Med. pmid:9518419
Yang YJ et al. Ten days of levofloxacin-containing concomitant therapy can achieve effective Helicobacter pylori eradication in patients with type 2 diabetes. 2017 Ann. Med. pmid:28266875
Trotti LM et al. Clarithromycin in γ-aminobutyric acid-Related hypersomnolence: A randomized, crossover trial. 2015 Ann. Neurol. pmid:26094838
Ferreri AJ et al. High-dose clarithromycin is an active monotherapy for patients with relapsed/refractory extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT): the HD-K phase II trial. 2015 Ann. Oncol. pmid:25935794
Di Raimondo F et al. Is endoscopic ultrasound clinically useful for follow-up of gastric lymphoma? 2007 Ann. Oncol. pmid:17065587
Rhee CS et al. Effects of clarithromycin on rheological properties of nasal mucus in patients with chronic sinusitis. 2000 Ann. Otol. Rhinol. Laryngol. pmid:10823478
Heffernan CB et al. Does Clarithromycin Cause Hearing Loss? A 12-Year Review of Clarithromycin Therapy for Nontuberculous Mycobacterial Lymphadenitis in Children. 2018 Ann. Otol. Rhinol. Laryngol. pmid:30032669
Clifford K et al. Double-blind comparative trial of ciprofloxacin versus clarithromycin in the treatment of acute bacterial sinusitis. Sinusitis Infection Study Group. 1999 Ann. Otol. Rhinol. Laryngol. pmid:10214783
Mullin D et al. Mycobacterium chelonae infections involving the head and neck. 2009 Ann. Otol. Rhinol. Laryngol. pmid:19894399
Callaghan R and Allen M Mycobacterium malmoense infection of the knee. 2003 Ann. Rheum. Dis. pmid:14583565
Hiramatsu M et al. Risk factors that affect the surgical outcome in the management of focal bronchiectasis in a developed country. 2012 Ann. Thorac. Surg. pmid:22119119
Fan X et al. Lung perfusion with clarithromycin ameliorates lung function after cardiopulmonary bypass. 2006 Ann. Thorac. Surg. pmid:16488691
Nelson KG et al. Results of operation in Mycobacterium avium-intracellulare lung disease. 1998 Ann. Thorac. Surg. pmid:9725364
Kadir IS et al. Recurrent acute rheumatic fever: a forgotten diagnosis? 2004 Ann. Thorac. Surg. pmid:15276555
Bossert T et al. Successful management of two heart transplant recipients with mycobacterial pulmonary infections. 2005 Ann. Thorac. Surg. pmid:16039241
Watanabe M et al. Early pulmonary resection for Mycobacterium avium complex lung disease treated with macrolides and quinolones. 2006 Ann. Thorac. Surg. pmid:16731124
Gintovt EA [Use of clarithromycin in the treatment of atopic dermatitis complicated by staphylococcal infection]. 2004 Antibiot. Khimioter. pmid:15164520
Vasil'ev IuV and Zvenigorodskaia LA [Fromilide (clarithromycin) in eradication of Helicobacter pylori in patients with duodenal ulcer]. 2002 Antibiot. Khimioter. pmid:12365323
Iakovlev EA et al. [Present stage of chemotherapy and chemoprophylaxis of rickettsiosis and Q fever]. 2011 Antibiot. Khimioter. pmid:22856156
Iakovlev VP [New semisynthetic macrolides. Clarithromycin--its importance in the current therapy of bacterial infections]. 1999 Antibiot. Khimioter. pmid:10635418
Evdokimova AG et al. [New approaches to therapy of Helicobacterpylori infection (by the materials of the Maastricht Consensus-IV, Florence, 2010)]. 2013 Antibiot. Khimioter. pmid:24640139
Iakovlev VP et al. [Macrolide antibiotic clarithromycin (Klabax) in treatment of community-acquired respiratory tract infections]. 2000 Antibiot. Khimioter. pmid:11210297
Shcherbakov PL [Clarithromycin in eradication therapy of helicobacter infections in children]. 2001 Antibiot. Khimioter. pmid:11871315
Sazykin IuO et al. [Clarithromycin and tumor chemotherapy]. 2000 Antibiot. Khimioter. pmid:11210301
Iutanova NS [Clinical efficacy of clarithromycin delayed release dosage form in the treatment of community-acquired pneumonia]. 2004 Antibiot. Khimioter. pmid:15344392
Budanov SV and Vasil'ev AN [Clarithromycin: specific features of antimicrobial spectrum and clinical use]. 2004 Antibiot. Khimioter. pmid:15285409
Guchev IA et al. [Evaluation of clarithromycin efficacy in the treatment of community-acquired pneumonia on the basis of the Binax NOW test results (a prospective open trial)]. 2002 Antibiot. Khimioter. pmid:12619516
Aoki D et al. Roxithromycin inhibits angiogenesis of human hepatoma cells in vivo by suppressing VEGF production. Anticancer Res. pmid:15816530
Ohara T et al. Antibiotics directly induce apoptosis in B cell lymphoma cells derived from BALB/c mice. 2004 Nov-Dec Anticancer Res. pmid:15736403
Morikawa K et al. Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. 1996 Antimicrob. Agents Chemother. pmid:8726002
Giacometti A et al. In vitro activity and killing effect of uperin 3.6 against gram-positive cocci isolated from immunocompromised patients. 2005 Antimicrob. Agents Chemother. pmid:16127075
Kim JM et al. Distribution of antibiotic MICs for Helicobacter pylori strains over a 16-year period in patients from Seoul, South Korea. 2004 Antimicrob. Agents Chemother. pmid:15561865
Endo H et al. Effects of clarithromycin and amoxicillin on gastric emptying in rats. 2002 Antimicrob. Agents Chemother. pmid:12234874
Goldstein EJ et al. Activities of telithromycin (HMR 3647, RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and other antimicrobial agents against unusual anaerobes. 1999 Antimicrob. Agents Chemother. pmid:10543769
Fernández-Roblas R et al. In vitro susceptibilities of rapidly growing mycobacteria to telithromycin (HMR 3647) and seven other antimicrobials. 2000 Antimicrob. Agents Chemother. pmid:10602744
Steele-Moore L et al. In vitro activities of clarithromycin and azithromycin against clinical isolates of Mycobacterium avium-M. intracellulare. 1999 Antimicrob. Agents Chemother. pmid:10383373
Rouse MS et al. Efficacy of azithromycin or clarithromycin for prophylaxis of viridans group streptococcus experimental endocarditis. 1997 Antimicrob. Agents Chemother. pmid:9257739
Cynamon MH et al. Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model. 2000 Antimicrob. Agents Chemother. pmid:10991883
Mor N et al. Effects of clarithromycin and rifabutin alone and in combination on intracellular and extracellular replication of Mycobacterium avium. 1994 Antimicrob. Agents Chemother. pmid:7695255
Lacassin F et al. Clarithromycin-minocycline combination as salvage therapy for toxoplasmosis in patients infected with human immunodeficiency virus. 1995 Antimicrob. Agents Chemother. pmid:7695324
Phillips RO et al. Reply to "compliance with antimicrobial therapy for buruli ulcer". 2014 Antimicrob. Agents Chemother. pmid:25225343
Meyer JM et al. In vitro synergy testing of clarithromycin and 14-hydroxyclarithromycin with amoxicillin or bismuth subsalicylate against Helicobacter pylori. 1997 Antimicrob. Agents Chemother. pmid:9210696
Lounis N et al. Selection of clarithromycin-resistant Mycobacterium avium complex during combined therapy using the beige mouse model. 1995 Antimicrob. Agents Chemother. pmid:7793860
Fattorini L et al. In vitro and ex vivo activities of antimicrobial agents used in combination with clarithromycin, with or without amikacin, against Mycobacterium avium. 1995 Antimicrob. Agents Chemother. pmid:7793873