clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Matsushima M and Takagi A | "Is it effective?" to "How to use it?": the era has changed in probiotics and functional food products against Helicobacter pylori infection. | 2012 | J. Gastroenterol. Hepatol. | pmid:22515805 |
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Huang YK et al. | Lansoprazole-based sequential and concomitant therapy for the first-line Helicobacter pylori eradication. | 2012 | J Dig Dis | pmid:22435509 |
Choi SJ et al. | The prevalence of vaginal microorganisms in pregnant women with preterm labor and preterm birth. | 2012 | Ann Lab Med | pmid:22563554 |
Bowers JR et al. | Dominance of multidrug resistant CC271 clones in macrolide-resistant streptococcus pneumoniae in Arizona. | 2012 | BMC Microbiol. | pmid:22251616 |
Brož P et al. | Nonirritant intradermal skin test concentrations of ciprofloxacin, clarithromycin, and rifampicin. | 2012 | Allergy | pmid:22435670 |
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Hojsak I et al. | Antibiotic resistance of Helicobacter pylori in pediatric patients -- 10 years' experience. | 2012 | Eur. J. Pediatr. | pmid:22430353 |
Koutsoubari I et al. | Effect of clarithromycin on acute asthma exacerbations in children: an open randomized study. | 2012 | Pediatr Allergy Immunol | pmid:22433020 |
Lin YH and Liu TC | Mycobacterium chelonae infection involving the auricle. | 2012 | QJM | pmid:21908384 |
Padovan J et al. | Investigating the barriers to bioavailability of macrolide antibiotics in the rat. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:22113743 |
Barberán J et al. | Update on the clinical utility and optimal use of cefditoren. | 2012 | Int J Gen Med | pmid:22675264 |
Park HS et al. | Placental transfer of clarithromycin in human pregnancies with preterm premature rupture of membranes. | 2012 | J Perinat Med | pmid:23095192 |
Kumar R et al. | Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22153939 |
Matsueda K et al. | A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia. | 2012 | Gut | pmid:22157329 |
Hutson JR et al. | Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study. | 2012 | Drugs Aging | pmid:22372724 |
Hegazy SK et al. | Effect of clarithromycin and fluconazole on the pharmacokinetics of montelukast in human volunteers. | 2012 | Eur. J. Clin. Pharmacol. | pmid:22392555 |
Valizadeh H et al. | Antibacterial activity of clarithromycin loaded PLGA nanoparticles. | 2012 | Pharmazie | pmid:22393833 |
Togami K et al. | Aerosol-based efficient delivery of clarithromycin, a macrolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections. | 2012 | J Aerosol Med Pulm Drug Deliv | pmid:22360316 |
Shiotani A et al. | H. pylori eradication did not improve dysregulation of specific oncogenic miRNAs in intestinal metaplastic glands. | 2012 | J. Gastroenterol. | pmid:22382634 |
Ding FM et al. | Low-dose clarithromycin therapy modulates CD4(+) T-cell responses in a mouse model of chronic Pseudomonas aeruginosa lung infection. | 2012 | Respirology | pmid:22404374 |
Kadayifci A et al. | Low efficacy of clarithromycin including sequential regimens for Helicobacter pylori infection. | 2012 | Helicobacter | pmid:22404442 |
Gisbert JP and McNicholl AG | Maintenance of Helicobacter pylori eradication rates with triple therapy over 12 years in a Spanish hospital. | 2012 | Helicobacter | pmid:22404448 |
Salmon JH et al. | Discitis and sacroiliitis diagnosed 15 years after iatrogenic Mycobacterium xenopi inoculation. | 2012 | Joint Bone Spine | pmid:22405857 |
Patel N and Miller CD | New option for management of HIV-1 infection in treatment-naive patients: once-daily, fixed-dose combination of rilpivirine-emtricitabine-tenofovir. | 2012 | HIV AIDS (Auckl) | pmid:22570576 |
Alzolibani AA and Zedan K | Macrolides in chronic inflammatory skin disorders. | 2012 | Mediators Inflamm. | pmid:22685371 |
Masekela R and Green RJ | The role of macrolides in childhood non-cystic fibrosis-related bronchiectasis. | 2012 | Mediators Inflamm. | pmid:22570510 |
Konorev MR | [Use of the immunopotentiator N-acetyl-glucosamine-N-acetylmuramyl dipeptide during triple anti-Helicobacter pylori therapy]. | 2012 | Ter. Arkh. | pmid:23479993 |
Inamo Y et al. | A 7-year-old girl with subcutaneous emphysema, pneumomediastinum, pneumothorax, and pneumoretroperitoneum caused by Mycoplasma pneumoniae pneumonia. | 2012 | J. Infect. Chemother. | pmid:21901497 |
Lee MR et al. | CNS infections caused by Mycobacterium abscessus complex: clinical features and antimicrobial susceptibilities of isolates. | 2012 | J. Antimicrob. Chemother. | pmid:21980068 |
Cuadrado-LavÃn A et al. | Antimicrobial susceptibility of Helicobacter pylori to six antibiotics currently used in Spain. | 2012 | J. Antimicrob. Chemother. | pmid:21965436 |
Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
Fujita J and Cash HL | Long-term combination treatment of azithromycin with other macrolides: a new era. | 2012 | Intern. Med. | pmid:22687831 |
Yamamoto Y et al. | A case of refractory chronic respiratory tract infection due to Pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin. | 2012 | Intern. Med. | pmid:22687847 |
Ivetic Tkalcevic V et al. | Cantharidin-induced inflammation in mouse ear model for translational research of novel anti-inflammatories. | 2012 | Transl Res | pmid:22677362 |
Cetin M et al. | Clarithromycin-Induced Long QT Syndrome: A Case Report. | 2012 | Case Rep Med | pmid:22489247 |
D'Elios MM et al. | Helicobacter pylori: usefulness of an empirical fourth-line rifabutin-based regimen. | 2012 | Expert Rev Gastroenterol Hepatol | pmid:22928895 |
Wu TS et al. | Fish tank granuloma caused by Mycobacterium marinum. | 2012 | PLoS ONE | pmid:22911774 |
Ikegame S et al. | Congenital cystic adenomatoid malformation in adulthood complicated by Mycobacterium celatum infection. | 2012 | Intern. Med. | pmid:22892504 |
Ngan LT et al. | Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. | 2012 | J. Agric. Food Chem. | pmid:22891951 |
Kao SS et al. | 7-Day Nonbismuth-Containing Concomitant Therapy Achieves a High Eradication Rate for Helicobacter pylori in Taiwan. | 2012 | Gastroenterol Res Pract | pmid:22888337 |
Shah M et al. | Transient Psychotic Episode Induced by Helicobacter pylori Triple Therapy Treatment. | 2012 | Case Rep Gastroenterol | pmid:22855656 |
Heeb F et al. | Organic micropollutants in rivers downstream of the megacity Beijing: sources and mass fluxes in a large-scale wastewater irrigation system. | 2012 | Environ. Sci. Technol. | pmid:22845779 |
Wu W et al. | Recent Insights into Antibiotic Resistance in Helicobacter pylori Eradication. | 2012 | Gastroenterol Res Pract | pmid:22829809 |
Choi GE et al. | Macrolide treatment for Mycobacterium abscessus and Mycobacterium massiliense infection and inducible resistance. | 2012 | Am. J. Respir. Crit. Care Med. | pmid:22878281 |
Kant S et al. | Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient. | 2012 | BMJ Case Rep | pmid:22605844 |
Korkmaz S et al. | Unusual manifestations of acute Q fever: autoimmune hemolytic anemia and tubulointerstitial nephritis. | 2012 | Ann. Clin. Microbiol. Antimicrob. | pmid:22607576 |
Oh HS et al. | Ten-day sequential therapy is more effective than proton pump inhibitor-based therapy in Korea: a prospective, randomized study. | 2012 | J. Gastroenterol. Hepatol. | pmid:21916989 |
Suzuki H et al. | Molecular approaches and modern clinical strategies for the management of Helicobacter pylori infection in Japan. | 2012 | Keio J Med | pmid:23324305 |
Wong BC et al. | Effects of selective COX-2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions. | 2012 | Gut | pmid:21917649 |
O'Connor MB et al. | Rituximab-induced pulmonary disease. | 2012 | Rheumatol. Int. | pmid:21892654 |
Nakagawa T et al. | [Multicenter study on clinical features and genetic characteristics of Mycobacterium avium strains from patients in Japan with lung disease caused by M. avium]. | 2012 | Kekkaku | pmid:23367826 |
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Fujita M et al. | The clinical efficacy and safety of a fluoroquinolone-containing regimen for pulmonary MAC disease. | 2012 | J. Infect. Chemother. | pmid:21927844 |
Uno K et al. | Rupture of renal mycotic aneurysm that developed during the treatment of streptococcal infective endocarditis and vertebral osteomyelitis. | 2012 | Intern. Med. | pmid:22687800 |
Sano N et al. | Comprehensive Analysis of Bacterial Flora in Postoperative Maxillary Cyst Fluid by 16S rRNA Gene and Culture Methods. | 2012 | ISRN Dent | pmid:22685668 |
Lambiase A et al. | In vitro resistance to macrolides and clindamycin by Group B Streptococcus isolated from pregnant and nonpregnant women. | 2012 | Infect Dis Obstet Gynecol | pmid:22675244 |
Tseng CH | Diabetes, insulin use and Helicobacter pylori eradication: a retrospective cohort study. | 2012 | BMC Gastroenterol | pmid:22571603 |
Park SK et al. | Regression of Advanced Gastric MALT Lymphoma after the Eradication of Helicobacter pylori. | 2012 | Gut Liver | pmid:22570759 |
Choi GE et al. | Activities of moxifloxacin in combination with macrolides against clinical isolates of Mycobacterium abscessus and Mycobacterium massiliense. | 2012 | Antimicrob. Agents Chemother. | pmid:22564831 |
Lu ZM et al. | Nucleosomes correlate with in vivo progression pattern of de novo methylation of p16 CpG islands in human gastric carcinogenesis. | 2012 | PLoS ONE | pmid:22558275 |
Raithatha AH and Bryden DC | Use of intravenous immunoglobulin therapy in the treatment of septic shock, in particular severe invasive group A streptococcal disease. | 2012 | Indian J Crit Care Med | pmid:22557832 |
Suzuki T | Meibomitis-related keratoconjunctivitis: implications and clinical significance of meibomian gland inflammation. | 2012 | Cornea | pmid:23038034 |
Ivetić TkalÄević V et al. | Topical azithromycin and clarithromycin inhibit acute and chronic skin inflammation in sensitized mice, with apparent selectivity for Th2-mediated processes in delayed-type hypersensitivity. | 2012 | Inflammation | pmid:21336676 |
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Yang YH et al. | Anti-Helicobacter pylori effects of IgY from egg york of immunized hens. | 2012 | Lab Anim Res | pmid:22474475 |
Godreuil S et al. | Mycobacterium riyadhense pulmonary infection, France and Bahrain. | 2012 | Emerging Infect. Dis. | pmid:22261434 |
Li H et al. | [Clarithromycin combined with tanshinone for rhinosinusal and laryngeal radiation injury in patients with nasopharyngeal carcinoma after radiotherapy]. | 2012 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:22931614 |
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van de Streek J | Reinterpretation of the monohydrate of clarithromycin from X-ray powder diffraction data as a trihydrate. | 2012 | Acta Crystallogr C | pmid:22935507 |
Pasqualetti G et al. | Clarithromycin-induced rhabdomyolysis: a case report. | 2012 | Int J Gen Med | pmid:22505827 |
Sachs G and Scott DR | Helicobacter pylori: Eradication or Preservation. | 2012 | F1000 Med Rep | pmid:22500191 |
Bataille S et al. | Vancomycin-induced Henoch-Schönlein purpura: a case report. | 2012 | J Med Case Rep | pmid:22490390 |
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Karne SS et al. | Mycobacterium avium-intracellulare brain abscess in HIV-positive patient. | 2012 | Ann Indian Acad Neurol | pmid:22412276 |
Yanai A et al. | Non-bismuth quadruple therapy for first-line Helicobacter pylori eradication: A randomized study in Japan. | 2012 | World J Gastrointest Pharmacol Ther | pmid:22408744 |
Carella AM et al. | Clarithromycin potentiates tyrosine kinase inhibitor treatment in patients with resistant chronic myeloid leukemia. | 2012 | Leuk. Lymphoma | pmid:22233113 |
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Kobashi Y et al. | Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin. | 2012 | Intern. Med. | pmid:22821114 |
Li Y et al. | A data-driven predictive approach for drug delivery using machine learning techniques. | 2012 | PLoS ONE | pmid:22384063 |
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