clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Rosacea D012393 13 associated lipids
Scrub Typhus D012612 3 associated lipids
Serositis D012700 1 associated lipids
Shock, Septic D012772 11 associated lipids
Sinusitis D012852 9 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Skin Neoplasms D012878 12 associated lipids
Skin Ulcer D012883 6 associated lipids
Splenic Diseases D013158 5 associated lipids
Sporotrichosis D013174 3 associated lipids
Stomach Diseases D013272 7 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Synovitis D013585 15 associated lipids
Syphilis D013587 6 associated lipids
Tenosynovitis D013717 3 associated lipids
Tooth Discoloration D014075 7 associated lipids
Tuberculosis D014376 20 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Tuberculosis, Ocular D014392 1 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Tuberculosis, Spinal D014399 1 associated lipids
Typhoid Fever D014435 2 associated lipids
Ureteral Diseases D014515 3 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Urethritis D014526 9 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Urination Disorders D014555 9 associated lipids
Urticaria D014581 13 associated lipids
Uveitis, Anterior D014606 11 associated lipids
Whooping Cough D014917 6 associated lipids
Wound Infection D014946 12 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Discitis D015299 2 associated lipids
Leprosy, Borderline D015439 3 associated lipids
Leprosy, Lepromatous D015440 2 associated lipids
Eye Injuries, Penetrating D015807 2 associated lipids
Eye Infections D015817 1 associated lipids
Eye Infections, Bacterial D015818 3 associated lipids
Lymphoma, T-Cell, Cutaneous D016410 4 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Bacteremia D016470 9 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Still's Disease, Adult-Onset D016706 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Ureaplasma Infections D016869 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Chen XX et al. [Long-term therapeutic effect of triple therapy consisted of omeperazole, clarithromycin and amoxycillin in children with Helicobacter pylori infection and approach to re-treatment after failure of the treatment]. 2004 Zhonghua Er Ke Za Zhi pmid:15265423
Wang Y et al. [Analysis of the infection status and the drug resistance of mycoplasma and chlamydiae in genitourinary tracts of children with suspected nongonococcal urethritis]. 2009 Zhonghua Er Ke Za Zhi pmid:19573386
Luo Q et al. [Clinical effect of clarithromycin therapy in patients with chronic rhinosinusitis]. 2014 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:24742507
Guo SB et al. [Preparation and identification of the oligonucleotide chip for detecting the virulence-associated genotypes and drug resistance of Helicobacter pylori]. 2007 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:17380677
Yang CS et al. [Study of correlation between Helicobacter pylori infection and hyperammonemia and hepatic encephalopathy in cirrhotic patients]. 2007 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:17631712
Zhao HM et al. [Clinical effect of triple therapy combined with Saccharomyces boulardii in the treatment of Helicobacter pylori infection in children]. 2014 Zhongguo Dang Dai Er Ke Za Zhi pmid:24661511
Huang LP et al. [Antimicrobial resistance of 36 strains of Helicobacter pylori in adolescents]. 2009 Zhongguo Dang Dai Er Ke Za Zhi pmid:19292962
Xiang L et al. [Different courses of esomeprazole-based triple therapy for Helicobactor pylori infection in children]. 2007 Zhongguo Dang Dai Er Ke Za Zhi pmid:17582255
Wang F et al. [Five-day rabeprazole-based triple therapy for helicobacter pylori infection]. 2004 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:16137055
Li Y et al. [Efficacy of 4 kinds of triple strategy for Helicobacter pylori eradication]. 2008 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:19141980
Wu S et al. [Anti-Helicobacter pylori treatment in patients with idiopathic thrombocytopenic purpura]. 2009 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:20045922
Wang F et al. [Antibiotic resistance of Helicobacter pylori]. 2007 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:17611323
Li F et al. [Effect of prokinetic agents on the electrical activity of stomach and duodenum in rats]. 2009 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:19648670
Tang D et al. [Efficacy of bismuth containing quadruple therapies on Helicobacter pylori eradication in patients with history of antibiotic treatment]. 2018 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:30124214
Tu S and Yang H [Progress in the treatment of Helicobacter pylori infection]. 2014 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:25269503
Gamova NA [Drug sensitivity of Ureaplasma urealyticum, persisting in patients with chronic inflammatory diseases of the urogenital tract]. 2003 Jul-Aug Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:12966887
Fabry W et al. Comparison of the E test and a proportion dilution method for susceptibility testing of Mycobacterium tuberculosis. 1995 Zentralbl. Bakteriol. pmid:9810662
Alter P et al. [Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis]. 2000 Z Kardiol pmid:11013974
Knothe H [Short-term therapy of acute respiratory and ORL infections with Clarithromycin]. 1992 Z Gesamte Inn Med pmid:9022402
Hellmeyer L et al. [Q Fever in pregnancy: a case report and review of the literature]. 2002 Sep-Oct Z Geburtshilfe Neonatol pmid:12395293