clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Rosacea D012393 13 associated lipids
Scrub Typhus D012612 3 associated lipids
Serositis D012700 1 associated lipids
Shock, Septic D012772 11 associated lipids
Sinusitis D012852 9 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Skin Neoplasms D012878 12 associated lipids
Skin Ulcer D012883 6 associated lipids
Splenic Diseases D013158 5 associated lipids
Sporotrichosis D013174 3 associated lipids
Stomach Diseases D013272 7 associated lipids
Stomach Neoplasms D013274 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Synovitis D013585 15 associated lipids
Syphilis D013587 6 associated lipids
Tenosynovitis D013717 3 associated lipids
Tooth Discoloration D014075 7 associated lipids
Tuberculosis D014376 20 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Tuberculosis, Ocular D014392 1 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Tuberculosis, Spinal D014399 1 associated lipids
Typhoid Fever D014435 2 associated lipids
Ureteral Diseases D014515 3 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Urethritis D014526 9 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Urination Disorders D014555 9 associated lipids
Urticaria D014581 13 associated lipids
Uveitis, Anterior D014606 11 associated lipids
Whooping Cough D014917 6 associated lipids
Wound Infection D014946 12 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Discitis D015299 2 associated lipids
Leprosy, Borderline D015439 3 associated lipids
Leprosy, Lepromatous D015440 2 associated lipids
Eye Injuries, Penetrating D015807 2 associated lipids
Eye Infections D015817 1 associated lipids
Eye Infections, Bacterial D015818 3 associated lipids
Lymphoma, T-Cell, Cutaneous D016410 4 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Bacteremia D016470 9 associated lipids
Helicobacter Infections D016481 21 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Still's Disease, Adult-Onset D016706 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Ureaplasma Infections D016869 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Sung JJ et al. One-week ranitidine bismuth citrate in combinations with metronidazole, amoxycillin and clarithromycin in the treatment of Helicobacter pylori infection: the RBC-MACH study. 1999 Aliment. Pharmacol. Ther. pmid:10468684
Catalano F et al. Comparative treatment of Helicobacter pylori-positive duodenal ulcer using pantoprazole at low and high doses versus omeprazole in triple therapy. 1999 Helicobacter pmid:10469192
Kamada T et al. Effect of smoking and histological gastritis severity on the rate of H. pylori eradication with omeprazole, amoxicillin, and clarithromycin. 1999 Helicobacter pmid:10469195
Bui KQ et al. Mononuclear and polymorphonuclear leukocyte dispositions of clarithromycin and azithromycin in AIDS patients requiring Mycobacterium avium complex prophylaxis. 1999 Antimicrob. Agents Chemother. pmid:10471584
Tanaka E et al. Effect of clarithromycin regimen for Mycobacterium avium complex pulmonary disease. 1999 Am. J. Respir. Crit. Care Med. pmid:10471610
Mikamo H et al. Adequate macrolide treatment schedules for uterine cervicitis caused by Chlamydia trachomatis. 1999 Sep-Oct Chemotherapy pmid:10473928
Geiderman JM Central nervous system disturbances following clarithromycin ingestion. 1999 Clin. Infect. Dis. pmid:10476775
Gómez Cubillos C et al. [Can macrolide treatment delay the diagnosis of tuberculosis?]. 1999 An Med Interna pmid:10481348
Sato K et al. [MICs and MBCs of levofloxacin, clarithromycin, and KRM-1648 for Mycobacterium tuberculosis and M. avium complex residing in MONO-MAC-6 human macrophage-like cell and A-549 human type II alveolar epithelial cell lines]. 1999 Kekkaku pmid:10481412
Gidoh M [The control leprous peripheral neuropathy and chemotherapy]. 1999 Nihon Hansenbyo Gakkai Zasshi pmid:10481449
Klapper SR and Patrinely JR Periocular atypical mycobacterial infections. 1999 Ophthalmology pmid:10485521
Matsuoka M et al. Simultaneous colonisation of Helicobacter pylori with and without mutations in the 23S rRNA gene in patients with no history of clarithromycin exposure. 1999 Gut pmid:10486356
Tyagi AK et al. An unreported side effect of topical clarithromycin when used successfully to treat Mycobacterium avium-intracellulare keratitis. 1999 Cornea pmid:10487437
Rodríguez Téllez M et al. Morphometric estimation of acid output in duodenal ulcer associated with Helicobacter pylori infection. 1999 Rev Esp Enferm Dig pmid:10491487
Gutiérrez-Cabano CA and Raynald AC Gastroprotective effect of intragastric clarithromycin against damage induced by ethanol in rats. 1999 Dig. Dis. Sci. pmid:10492159
Moore PA Dental therapeutic indications for the newer long-acting macrolide antibiotics. 1999 J Am Dent Assoc pmid:10492541
Osato MS et al. Metronidazole and clarithromycin resistance amongst Helicobacter pylori isolates from a large metropolitan hospital in the United States. 1999 Int. J. Antimicrob. Agents pmid:10493611
Hirsh DC and Jang SS Antimicrobial susceptibility of Nocardia nova isolated from five cats with nocardiosis. 1999 J. Am. Vet. Med. Assoc. pmid:10496134
Ellenrieder V et al. Prevalence of resistance to clarithromycin and its clinical impact on the efficacy of Helicobacter pylori eradication. 1999 Scand. J. Gastroenterol. pmid:10499474
Zgoulli S et al. Microencapsulation of erythromycin and clarithromycin using a spray-drying technique. 1999 Sep-Oct J Microencapsul pmid:10499837