| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ureteral Obstruction | D014517 | 10 associated lipids |
| Rodent Diseases | D012376 | 4 associated lipids |
| Osteomyelitis | D010019 | 10 associated lipids |
| Pancreatitis | D010195 | 10 associated lipids |
| Skin Ulcer | D012883 | 6 associated lipids |
| Cysts | D003560 | 4 associated lipids |
| Urination Disorders | D014555 | 9 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Huang CC et al. | In vitro activity of aminoglycosides, clofazimine, d-cycloserine and dapsone against 83 Mycobacterium avium complex clinical isolates. | 2018 | J Microbiol Immunol Infect | pmid:28705770 |
| Kelly C et al. | Macrolide antibiotics for bronchiectasis. | 2018 | Cochrane Database Syst Rev | pmid:29543980 |
| Yeo YH et al. | First-line eradication therapies in countries with high and low clarithromycin resistance: a systematic review and network meta-analysis. | 2018 | Gut | pmid:27670375 |
| Suzuki R et al. | Sinobronchial syndrome treated as intractable asthma. | 2018 | Pediatr Int | pmid:30320426 |
| Mégraud F | Antibiotic Resistance Is the Key Element in Treatment of Helicobacter pylori Infection. | 2018 | Gastroenterology | pmid:30308190 |
| Mieras LF et al. | An enhanced regimen as post-exposure chemoprophylaxis for leprosy: PEP+. | 2018 | BMC Infect. Dis. | pmid:30290790 |
| Liou JM et al. | Toward population specific and personalized treatment of Helicobacter pylori infection. | 2018 | J. Biomed. Sci. | pmid:30285834 |
| Liu HY et al. | Bilateral Non-tuberculous Mycobacterial Keratitis After Small Incision Lenticule Extraction. | 2018 | J Refract Surg | pmid:30199569 |
| Kabakambira JD et al. | Efficacy of Helicobacter pylori eradication regimens in Rwanda: a randomized controlled trial. | 2018 | BMC Gastroenterol | pmid:30165823 |
| Yotsu RR et al. | Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease). | 2018 | Cochrane Database Syst Rev | pmid:30136733 |
| Tang D et al. | [Efficacy of bismuth containing quadruple therapies on Helicobacter pylori eradication in patients with history of antibiotic treatment]. | 2018 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:30124214 |
| Byeon JY et al. | Effects of genetic polymorphisms of CYP2C19 on the pharmacokinetics of zolpidem. | 2018 | Arch. Pharm. Res. | pmid:30117082 |
| Park CG et al. | Clinical relevance of point mutations in the 23S rRNA gene in Helicobacter pylori eradication: A prospective, observational study. | 2018 | Medicine (Baltimore) | pmid:30113472 |
| Morgene MF et al. | HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics. | 2018 | Virology | pmid:30077071 |
| Shinozaki S et al. | Pre-treatment with proton pump inhibitors decreases the success of primary Helicobacter pylori eradication using a vonoprazan-based regimen. | 2018 | Kaohsiung J. Med. Sci. | pmid:30041763 |
| Iannone A et al. | New fecal test for non-invasive detection: A diagnostic accuracy study. | 2018 | World J. Gastroenterol. | pmid:30038469 |
| Heffernan CB et al. | Does Clarithromycin Cause Hearing Loss? A 12-Year Review of Clarithromycin Therapy for Nontuberculous Mycobacterial Lymphadenitis in Children. | 2018 | Ann. Otol. Rhinol. Laryngol. | pmid:30032669 |
| Hamza D et al. | Genotyping and antimicrobial resistance patterns of Helicobacter pylori in human and dogs associated with A2142G and A2143G point mutations in clarithromycin resistance. | 2018 | Microb. Pathog. | pmid:30031039 |
| Vianna JS et al. | The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in Helicobacter pylori. | 2018 | Rev. Inst. Med. Trop. Sao Paulo | pmid:29972462 |
| Myojin S et al. | Chronic otitis media caused by Mycobacterium abscessus spp. massiliense treated with tigecycline in a 10-year-old child. | 2018 | Int. J. Infect. Dis. | pmid:29966711 |
| Liou JM et al. | Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection. | 2018 | Gastroenterology | pmid:29964036 |
| Kwofie SK et al. | Screening of Isocitrate Lyase for Novel Anti-Buruli Ulcer Natural Products Originating from Africa. | 2018 | Molecules | pmid:29954088 |
| Abu-Khalaf N et al. | The Taste of Commercially Available Clarithromycin Oral Pharmaceutical Suspensions in the Palestinian Market: Electronic Tongue and In Vivo Evaluation. | 2018 | Sensors (Basel) | pmid:29401675 |
| Tanabe H et al. | Vonoprazan-based triple therapy is non-inferior to susceptibility-guided proton pump inhibitor-based triple therapy for Helicobacter pylori eradication. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29950163 |
| Sandri A et al. | Inhibition of Pseudomonas aeruginosa secreted virulence factors reduces lung inflammation in CF mice. | 2018 | Virulence | pmid:29938577 |
| Gonzalez-Hormazabal P et al. | Prevalence of clarithromycin resistance in Helicobacter pylori in Santiago, Chile, estimated by real-time PCR directly from gastric mucosa. | 2018 | BMC Gastroenterol | pmid:29925321 |
| Clarithromycin in patients with coronary artery disease. | 2018 | Med Lett Drugs Ther | pmid:29913468 | |
| Li M et al. | Systematic review with meta-analysis: Vonoprazan, a potent acid blocker, is superior to proton-pump inhibitors for eradication of clarithromycin-resistant strains of Helicobacter pylori. | 2018 | Helicobacter | pmid:29873436 |
| Blümel B et al. | Retrospective study on outcome of salvage Helicobacter pylori eradication therapies based on molecular genetic susceptibility testing. | 2018 | Helicobacter | pmid:29873430 |
| Ito M et al. | Phase transitions of antibiotic clarithromycin forms I, IV and new form VII crystals. | 2018 | Int J Pharm | pmid:29864514 |
| Jin BH et al. | Pharmacokinetic drug interaction and safety after coadministration of clarithromycin, amoxicillin, and ilaprazole: a randomised, open-label, one-way crossover, two parallel sequences study. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29846770 |
| Auesomwang C et al. | Ten-day high-dose proton pump inhibitor triple therapy versus sequential therapy for Helicobacter pylori eradication. | 2018 | J. Gastroenterol. Hepatol. | pmid:29804294 |
| Chai KY et al. | Roxithromycin monotherapy inducing a partial response in a patient with myeloma: a case report. | 2018 | J Med Case Rep | pmid:29743095 |
| Strouvalis I et al. | Early increase of VEGF-A is associated with resolution of ventilator-associated pneumonia: Clinical and experimental evidence. | 2018 | Respirology | pmid:29741298 |
| Long X et al. | Bismuth improves efficacy of proton-pump inhibitor clarithromycin, metronidazole triple Helicobacter pylori therapy despite a high prevalence of antimicrobial resistance. | 2018 | Helicobacter | pmid:29696736 |
| Fiorini G et al. | Antibiotic resistance pattern of Helicobacter pylori strains isolated in Italy during 2010-2016. | 2018 | Scand. J. Gastroenterol. | pmid:29688095 |
| Matta AJ et al. | Punctual mutations in gene of clarithromycin-resistant in Colombian populations. | 2018 | World J. Gastroenterol. | pmid:29662291 |
| RodrÃguez-Sevilla G et al. | Influence of three-dimensional lung epithelial cells and interspecies interactions on antibiotic efficacy against Mycobacterium abscessus and Pseudomonas aeruginosa. | 2018 | Pathog Dis | pmid:29648588 |
| Namkoong H et al. | Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia. | 2018 | PLoS Pathog. | pmid:29621339 |
| Berende A et al. | Cost-effectiveness of longer-term versus shorter-term provision of antibiotics in patients with persistent symptoms attributed to Lyme disease. | 2018 | PLoS ONE | pmid:29608590 |
| Mabe K et al. | Randomized controlled trial: PPI-based triple therapy containing metronidazole versus clarithromycin as first-line treatment for Helicobacter pylori in adolescents and young adults in Japan. | 2018 | J. Infect. Chemother. | pmid:29605555 |
| Chen SA et al. | HLA-A*02:07 Allele Associates with Clarithromycin-Induced Cutaneous Adverse Drug Reactions in Chinese Patients. | 2018 | Basic Clin. Pharmacol. Toxicol. | pmid:29575644 |
| van Dyk M et al. | Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29572563 |
| Chen J et al. | Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29562911 |
| RodrÃguez-Sevilla G et al. | Non-Tuberculous Mycobacteria multispecies biofilms in cystic fibrosis: development of an in vitro Mycobacterium abscessus and Pseudomonas aeruginosa dual species biofilm model. | 2018 | Int. J. Med. Microbiol. | pmid:29555180 |
| Leung WK et al. | Effects of Helicobacter pylori Treatment on Incidence of Gastric Cancer in Older Individuals. | 2018 | Gastroenterology | pmid:29550592 |
| Kusuki M et al. | Determination of the antimicrobial susceptibility and molecular profile of clarithromycin resistance in the Mycobacterium abscessus complex in Japan by variable number tandem repeat analysis. | 2018 | Diagn. Microbiol. Infect. Dis. | pmid:29550059 |
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| Talarico S et al. | High prevalence of Helicobacter pylori clarithromycin resistance mutations among Seattle patients measured by droplet digital PCR. | 2018 | Helicobacter | pmid:29480566 |
| Takemori N et al. | A novel combination of bortezomib, lenalidomide, and clarithromycin produced stringent complete response in refractory multiple myeloma complicated with diabetes mellitus - clinical significance and possible mechanisms: a case report. | 2018 | J Med Case Rep | pmid:29454372 |
| Xu R et al. | Application of physiologically based pharmacokinetic modeling to the prediction of drug-drug and drug-disease interactions for rivaroxaban. | 2018 | Eur. J. Clin. Pharmacol. | pmid:29453492 |
| Tsutsui A et al. | Trends and patterns of national antimicrobial consumption in Japan from 2004 to 2016. | 2018 | J. Infect. Chemother. | pmid:29428566 |
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| Wang S et al. | Enhanced adsorption of ionizable antibiotics on activated carbon fiber under electrochemical assistance in continuous-flow modes. | 2018 | Water Res. | pmid:29426033 |
| Yagbasan A et al. | A Prospective, randomized study comparing 7-day and 14-day quadruple therapies as first-line treatments for helicobacter pylori infection in patients with functional dyspepsia. | 2018 | Niger J Clin Pract | pmid:29411724 |
| Maiolino G et al. | Macrolides for KCNJ5-mutated aldosterone-producing adenoma (MAPA): design of a study for personalized diagnosis of primary aldosteronism. | 2018 | Blood Press. | pmid:29409357 |
| Takahashi E et al. | Clarithromycin suppresses induction of monocyte chemoattractant protein-1 and matrix metalloproteinase-9 and improves pathological changes in the lungs and heart of mice infected with influenza A virus. | 2018 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:29406285 |
| Wang YH et al. | A systematic review and meta-analysis of genotypic methods for detecting antibiotic resistance in Helicobacter pylori. | 2018 | Helicobacter | pmid:29405526 |
| Tso S et al. | Clarithromycin as a steroid sparing agent for the management of infantile bullous pemphigoid. | 2018 | BMJ Case Rep | pmid:29374651 |
| Sahara S et al. | Efficacy of Reduced Dosage of Amoxicillin in an Eradication Therapy for Helicobacter pylori Infection in Patients on Hemodialysis: A Randomized Controlled Trial. | 2018 | Digestion | pmid:29310119 |
| Aderemi AO et al. | Oxidative stress responses and cellular energy allocation changes in microalgae following exposure to widely used human antibiotics. | 2018 | Aquat. Toxicol. | pmid:30125766 |
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| Nakase K et al. | Long-term administration of oral macrolides for acne treatment increases macrolide-resistant Propionibacterium acnes. | 2018 | J. Dermatol. | pmid:29235673 |
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| Muñoz-Gómez P et al. | Macrolide use in the previous years is associated with failure to eradicate Helicobacter pylori with clarithromycin-containing regimens. | 2018 | Helicobacter | pmid:29178562 |
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| Haj Yahia S et al. | Colchicine intoxication in familial Mediterranean fever patients using clarithromycin for the treatment of Helicobacter pylori: a series of six patients. | 2018 | Rheumatol. Int. | pmid:28975396 |
| Shaharir SS et al. | Non-tuberculous mycobacterium bacteraemia in a pregnant systemic lupus erythematosus (SLE) patient: a case review and pooled case analysis. | 2018 | Clin. Rheumatol. | pmid:28971307 |
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| Hosono Y et al. | The association between erythromycin monotherapy for Mycobacterium avium complex lung disease and cross-resistance to clarithromycin: A retrospective case-series study. | 2018 | J. Infect. Chemother. | pmid:29361415 |
| Ullah S et al. | Hydrophilically modified self-assembling α-tocopherol derivative as niosomal nanocarrier for improving clarithromycin oral bioavailability. | 2018 | Artif Cells Nanomed Biotechnol | pmid:28541761 |
| Sancak S et al. | A pioneering study: oral clarithromycin treatment for feeding intolerance in very low birth weight preterm infants. | 2018 | J. Matern. Fetal. Neonatal. Med. | pmid:28279123 |
| Yoshida S et al. | Association between sequevar and antibiotic treatment outcome in patients with Mycobacterium abscessus complex infections in Japan. | 2018 | J. Med. Microbiol. | pmid:29227218 |
| Alenezi A et al. | Controlled release of clarithromycin from PLGA microspheres enhances bone regeneration in rabbit calvaria defects. | 2018 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:28067984 |
| Cheung KS et al. | Long-term proton pump inhibitors and risk of gastric cancer development after treatment for : a population-based study. | 2018 | Gut | pmid:29089382 |
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