| MeSH term | MeSH ID | Detail |
|---|---|---|
| Ureteral Obstruction | D014517 | 10 associated lipids |
| Rodent Diseases | D012376 | 4 associated lipids |
| Osteomyelitis | D010019 | 10 associated lipids |
| Pancreatitis | D010195 | 10 associated lipids |
| Skin Ulcer | D012883 | 6 associated lipids |
| Cysts | D003560 | 4 associated lipids |
| Urination Disorders | D014555 | 9 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
| Siamas K and Khachemoune A | Mycobacteria infection in an immunocompetent patient with no risk factors: evaluation and management of non-healing majocchi granuloma-type nodule. | 2013 | Dermatol. Online J. | pmid:24021439 |
| Xu Y et al. | Synthesis and antibacterial activity of novel modified 5-O-mycaminose 14-membered ketolides. | 2013 | Eur J Med Chem | pmid:24021890 |
| Ranganathan D et al. | Mycobacterium fortuitum peritonitis in a patient receiving continuous ambulatory peritoneal dialysis. | 2013 | Saudi J Kidney Dis Transpl | pmid:24029271 |
| Krashias G et al. | Prevalence of Helicobacter pylori cagA and vacA genes in Cypriot patients. | 2013 | J Infect Dev Ctries | pmid:24042099 |
| Nguyen L and Taylor-Gjevre RM | An emerging role for clarithromycin in adult-onset still disease? | 2013 | J Clin Rheumatol | pmid:24048102 |
| Trespalacios AA et al. | Phenotypic and genotypic analysis of clarithromycin-resistant Helicobacter pylori from Bogotá D.C., Colombia. | 2013 | J. Microbiol. | pmid:23990295 |
| Saviola G et al. | Clarithromycin in rheumatoid arthritis: the addition to methotrexate and low-dose methylprednisolone induces a significant additive value--a 24-month single-blind pilot study. | 2013 | Rheumatol. Int. | pmid:23864141 |
| Amado-RodrÃguez L et al. | Anti-inflammatory effects of clarithromycin in ventilator-induced lung injury. | 2013 | Respir. Res. | pmid:23663489 |
| Mikamo H et al. | [Infection and host reaction]. | 2013 | Jpn J Antibiot | pmid:24649796 |
| Evdokimova AG et al. | [New approaches to therapy of Helicobacterpylori infection (by the materials of the Maastricht Consensus-IV, Florence, 2010)]. | 2013 | Antibiot. Khimioter. | pmid:24640139 |
| Onal IK et al. | What is the impact of Helicobacter pylori density on the success of eradication therapy: a clinico-histopathological study. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23796974 |
| de Zeeuw J et al. | Serum levels of neopterin during antimicrobial treatment for Mycobacterium ulcerans infection. | 2013 | Am. J. Trop. Med. Hyg. | pmid:23836576 |
| Janković B et al. | Consolidation trend design based on Young's modulus of clarithromycin single crystals. | 2013 | Int J Pharm | pmid:23872226 |
| Shinahara W et al. | Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis. | 2013 | PLoS ONE | pmid:23875018 |
| Friedman ND et al. | Mycobacterium ulcerans disease: experience with primary oral medical therapy in an Australian cohort. | 2013 | PLoS Negl Trop Dis | pmid:23875050 |
| Yano K et al. | Clinical outcome of the chronic flexor tenosynovitis in the hand caused by non-tuberculous mycobacterium treated by extensive tenosynovectomy and drugs. | 2013 | J Plast Surg Hand Surg | pmid:23875916 |
| Venerito M et al. | Meta-analysis of bismuth quadruple therapy versus clarithromycin triple therapy for empiric primary treatment of Helicobacter pylori infection. | 2013 | Digestion | pmid:23880479 |
| Kim SG et al. | [Guidelines for the diagnosis and treatment of Helicobacter pylori infection in Korea, 2013 revised edition]. | 2013 | Korean J Gastroenterol | pmid:23954956 |
| Yoshida S et al. | Further isolation of Mycobacterium abscessus subsp. abscessus and subsp. bolletii in different regions of Japan and susceptibility of these isolates to antimicrobial agents. | 2013 | Int. J. Antimicrob. Agents | pmid:23850022 |
| Gibbins NE et al. | Time to reconsider guidelines on clarithromycin in chronic rhinosinusitis? | 2013 | BMJ | pmid:23635541 |
| Pilcer G et al. | Carrier-free combination for dry powder inhalation of antibiotics in the treatment of lung infections in cystic fibrosis. | 2013 | Int J Pharm | pmid:23643509 |
| Rimbara E et al. | Helicobacter cinaedi and Helicobacter fennelliae transmission in a hospital from 2008 to 2012. | 2013 | J. Clin. Microbiol. | pmid:23658263 |
| Bismuth + metronidazole + tetracycline. Why risk adding bismuth? | 2013 | Prescrire Int | pmid:23662315 | |
| Zhuo FL et al. | Clinical isolates of Mycobacterium abscessus in Guangzhou area most possibly from the environmental infection showed variable susceptibility. | 2013 | Chin. Med. J. | pmid:23673103 |
| Seck A et al. | Primary antibiotic resistance and associated mechanisms in Helicobacter pylori isolates from Senegalese patients. | 2013 | Ann. Clin. Microbiol. Antimicrob. | pmid:23298145 |
| Rossi A et al. | BiRd (clarithromycin, lenalidomide, dexamethasone): an update on long-term lenalidomide therapy in previously untreated patients with multiple myeloma. | 2013 | Blood | pmid:23299315 |
| Singh RP et al. | Antimicrobial prophylaxis in open reduction and internal fixation of compound mandibular fractures: a collaborative regional audit of outcome. | 2013 | Br J Oral Maxillofac Surg | pmid:23369782 |
| Prasertpetmanee S et al. | Improved efficacy of proton pump inhibitor - amoxicillin - clarithromycin triple therapy for Helicobacter pylori eradication in low clarithromycin resistance areas or for tailored therapy. | 2013 | Helicobacter | pmid:23356886 |
| Nakamura Y et al. | Optimal duration of macrolide treatment for chronic sinusitis after endoscopic sinus surgery. | 2013 | Auris Nasus Larynx | pmid:23107100 |
| Kazama I and Maruyama Y | Differential effects of clarithromycin and azithromycin on delayed rectifier K(+)-channel currents in murine thymocytes. | 2013 | Pharm Biol | pmid:23527897 |
| Uthman MM et al. | Interventions for the prevention of mycobacterium avium complex in adults and children with HIV. | 2013 | Cochrane Database Syst Rev | pmid:23633339 |
| Wu Y et al. | Overexpression of YKL-40 predicts plaque instability in carotid atherosclerosis with CagA-positive Helicobacter pylori infection. | 2013 | PLoS ONE | pmid:23573226 |
| Koh WJ et al. | Reply: drug concentration monitoring in Mycobacterium avium lung disease: problems with methods and conclusions. | 2013 | Am. J. Respir. Crit. Care Med. | pmid:23577353 |
| Schmitt BH et al. | PCR detection of clarithromycin-susceptible and -resistant Helicobacter pylori from formalin-fixed, paraffin-embedded gastric biopsies. | 2013 | Mod. Pathol. | pmid:23579617 |
| Lai J et al. | Epithelioid histiocytic infiltrate caused by Mycobacterium scrofulaceum infection: a potential mimic of various neoplastic entities. | 2013 | Am J Dermatopathol | pmid:22935892 |
| Boyanova L et al. | Living in Sofia is associated with a risk for antibiotic resistance in Helicobacter pylori: a Bulgarian study. | 2013 | Folia Microbiol. (Praha) | pmid:23580173 |
| Bradbeer L et al. | Childhood headache and H. pylori--a possible association. | 2013 | Aust Fam Physician | pmid:23529524 |
| Yula E et al. | Detection of primary clarithromycin resistance of Helicobacter pylori and association between cagA (+) status and clinical outcome. | 2013 | Folia Microbiol. (Praha) | pmid:22956464 |
| Zhou L et al. | Cutaneous Mycobacterium intracellulare infection in an immuno-competent person. | 2013 | Acta Derm. Venereol. | pmid:23532357 |
| Marin AC et al. | A review of rescue regimens after clarithromycin-containing triple therapy failure (for Helicobacter pylori eradication). | 2013 | Expert Opin Pharmacother | pmid:23537368 |
| Liu MK et al. | Randomized trial comparing rabeprazole- versus lansoprazole-based Helicobacter pylori eradication regimens. | 2013 | Kaohsiung J. Med. Sci. | pmid:23768702 |
| Li XM et al. | Telithromycin versus clarithromycin for the treatment of community-acquired respiratory tract infections: a meta-analysis of randomized controlled trials. | 2013 | Chin. Med. J. | pmid:23769580 |
| Asaoka D et al. | Trends of second-line eradication therapy for Helicobacter pylori in Japan: a multicenter study in the Tokyo metropolitan area. | 2013 | Helicobacter | pmid:23773231 |
| Al-Haj A et al. | Method development, validation and bioequivalence of varenicline in human plasma by liquid chromatography tandem mass spectrometry. | 2013 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:23774248 |
| Quinney SK et al. | Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin. | 2013 | Eur. J. Clin. Pharmacol. | pmid:22777148 |
| Kim T et al. | [Clarithromycin-resistant Helicobacter pylori associated with 23S rRNA point mutations in Jeju Island]. | 2013 | Korean J Gastroenterol | pmid:23756666 |
| Georgopoulos SD et al. | Clinical evaluation of a ten-day regimen with esomeprazole, metronidazole, amoxicillin, and clarithromycin for the eradication of Helicobacter pylori in a high clarithromycin resistance area. | 2013 | Helicobacter | pmid:23714140 |
| Koh WJ et al. | Successful treatment of Mycobacterium massiliense lung disease with oral antibiotics only. | 2013 | Antimicrob. Agents Chemother. | pmid:23183432 |
| Moriya S et al. | Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. | 2013 | Int. J. Oncol. | pmid:23546223 |