clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Can C et al. | Symmetrical drug-related intertriginous and flexural exanthema induced by two different antibiotics. | Allergol Immunopathol (Madr) | pmid:23253684 | |
| Agha Z et al. | Is antibiotic prophylaxis for bacterial endocarditis cost-effective? | Med Decis Making | pmid:15951458 | |
| Hens DK et al. | Epidemic strain Shigella dysenteriae Type 1 Dt66 encodes several drug resistances by chromosome. | Arch. Med. Res. | pmid:15950082 | |
| Caliskan R et al. | Antimicrobial resistance of Helicobacter pylori strains to five antibiotics, including levofloxacin, in Northwestern Turkey. | Rev. Soc. Bras. Med. Trop. | pmid:26108005 | |
| Vlachogianni P et al. | Mycobacterium avium Auricular Infection in an Apparent Immunocompetent Patient: A Case Report. | Folia Med (Plovdiv) | pmid:27552790 | |
| Aoki D et al. | Roxithromycin inhibits angiogenesis of human hepatoma cells in vivo by suppressing VEGF production. | Anticancer Res. | pmid:15816530 | |
| Koh WJ et al. | Nontuberculous mycobacterial pulmonary diseases in immunocompetent patients. | Korean J Radiol | pmid:12271159 | |
| Yang X et al. | Comparison Between Sequential Therapy and Modified Bismuth-Included Quadruple Therapy for Helicobacter pylori Eradication in Chinese Patients. | Am J Ther | pmid:25923229 | |
| Mégraud F | Failed Eradication for Helicobacter pylori. What Should Be Done? | Dig Dis | pmid:27332826 | |
| Martins GM et al. | MOLECULAR DETECTION OF CLARITHROMYCIN AND FLUOROQUINOLONES RESISTANCE IN HELICOBACTER PYLORI INFECTION, DIRECTLY APPLIED TO GASTRIC BIOPSIES, IN AN URBAN BRAZILIAN POPULATION. | Arq Gastroenterol | pmid:27305419 | |
| Wani FA et al. | Antibiotic resistance in : A mutational analysis from a tertiary care hospital in Kashmir, India. | Indian J Med Microbiol | pmid:30084422 | |
| Pombo Romero J et al. | [Evaluation of the pilot program of medicine dispensation in customized doses in Galicia [Spain]]. | Gac Sanit | pmid:17306181 | |
| Rech TF et al. | Helicobacter pylori eradication: influence of interleukin-1beta -31 C/T polymorphism. | Braz J Infect Dis | pmid:30048609 | |
| Wang B et al. | In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates. | Swiss Med Wkly | pmid:30044468 | |
| Jeon JS et al. | Detection of clarithromycin-resistant by polymerase chain reaction using residual samples from rapid urease test. | Indian J Med Microbiol | pmid:29063887 | |
| Hu JL et al. | Optimized high-dose amoxicillin-proton-pump inhibitor dual therapies fail to achieve high cure rates in China. | Saudi J Gastroenterol | pmid:28937021 | |
| Walicka M et al. | Mycoplasma pneumoniae-induced pneumonia with Stevens-Johnson syndrome of acute atypical course. | Pol. Arch. Med. Wewn. | pmid:18714743 | |
| Bartnik W | Clinical aspects of Helicobacter pylori infection. | Pol. Arch. Med. Wewn. | pmid:18714738 | |
| Kempen JH | Medical management of human immunodeficiency virus infection. | Indian J Ophthalmol | pmid:18711266 | |
| Christodoulou C et al. | Quetiapine and clarithromycin-induced neuroleptic malignant syndrome. | Clin Neuropharmacol | pmid:25580921 | |
| Feng L et al. | Sequential Therapy or Standard Triple Therapy for Helicobacter pylori Infection: An Updated Systematic Review. | Am J Ther | pmid:25569598 | |
| Al Majid FM | Peritonitis due to Mycobacterium fortuitum following gastric banding. | Saudi J Gastroenterol | pmid:20339182 | |
| Shokrzadeh L et al. | Antibiotic susceptibility profile of Helicobacter pylori isolated from the dyspepsia patients in Tehran, Iran. | Saudi J Gastroenterol | pmid:21727733 | |
| Arora S et al. | Amoxicillin loaded chitosan-alginate polyelectrolyte complex nanoparticles as mucopenetrating delivery system for h. Pylori. | Sci Pharm | pmid:21886911 | |
| Hasan SR et al. | Short-duration furazolidone therapy in combination with amoxicillin, bismuth subcitrate, and omeprazole for eradication of Helicobacter pylori. | Saudi J Gastroenterol | pmid:20065568 | |
| Ling TK et al. | In vitro activity and post-antibiotic effect of quinupristin/dalfopristin (Synercid). | Chemotherapy | pmid:11399860 | |
| Gokhale NS | Medical management approach to infectious keratitis. | Indian J Ophthalmol | pmid:18417822 | |
| Asgari B et al. | HONEY-DERIVED LACTOBACILLUS RHAMNOSUS ALLEVIATES HELICOBACTER PYLORI-INDUCED GASTRO-INTESTINAL INFECTION AND GASTRIC INFLAMMATION IN C57BL/6 MICE: AN IMMUNO-HISTOLOGIC STUDY. | Arq Gastroenterol | pmid:30540092 | |
| Varghese B et al. | First case report of chronic pulmonary lung disease caused by Mycobacterium abscessus in two immunocompetent patients in Saudi Arabia. | Ann Saudi Med | pmid:22588446 | |
| Zhu C et al. | Prevalence and antimicrobial susceptibility of Ureaplasma urealyticum and Mycoplasma hominis in Chinese women with genital infectious diseases. | Indian J Dermatol Venereol Leprol | pmid:22565456 | |
| Bernstein JM and Bacheller CD | It's on the tip of my tongue. | Skinmed | pmid:16687984 | |
| Chang NL et al. | Clarithromycin-Induced Torsades de Pointes. | Am J Ther | pmid:25057773 | |
| Alkim H et al. | Role of Bismuth in the Eradication of Helicobacter pylori. | Am J Ther | pmid:26808355 | |
| Bezmin Abadi AT et al. | Inefficiency of rapid urease test for confirmation of Helicobacter pylori. | Saudi J Gastroenterol | pmid:21196663 | |
| Clark SE et al. | Identification of a multidrug efflux pump in Flavobacterium johnsoniae. | Vet. Res. | pmid:19558960 | |
| Chen YI and Fallone CA | A 14-day course of triple therapy is superior to a 10-day course for the eradication of Helicobacter pylori: A Canadian study conducted in a 'real world' setting. | Can J Gastroenterol Hepatol | pmid:26301332 |