clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Gram-Negative Bacterial Infections D016905 16 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Meningitis, Bacterial D016920 6 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
IgA Deficiency D017098 2 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Cutaneous Fistula D017577 1 associated lipids
Kleine-Levin Syndrome D017593 1 associated lipids
Periodontal Attachment Loss D017622 7 associated lipids
Soft Tissue Injuries D017695 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Cytomegalovirus Retinitis D017726 2 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Cardiovascular Abnormalities D018376 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Soft Tissue Infections D018461 2 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Cryptogenic Organizing Pneumonia D018549 3 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Tooth, Nonvital D019553 2 associated lipids
alpha 1-Antitrypsin Deficiency D019896 3 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Epilepsy, Partial, Motor D020938 1 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Renal Insufficiency D051437 8 associated lipids
Immune Reconstitution Inflammatory Syndrome D054019 1 associated lipids
Buruli Ulcer D054312 1 associated lipids
Extensively Drug-Resistant Tuberculosis D054908 1 associated lipids
Leprosy, Paucibacillary D056005 2 associated lipids
Upper Extremity Deep Vein Thrombosis D056824 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Sacroiliitis D058566 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Geraci AJ Empiric antibiotics in sinusitis. 1994 Arch Fam Med pmid:7921288
Rust GS Multicenter comparison of clarithromycin and amoxicillin. 1994 Arch Fam Med pmid:7921290
Dorrell L et al. Toxicity of clarithromycin in the treatment of Mycobacterium avium complex infection in a patient with AIDS. 1994 J. Antimicrob. Chemother. pmid:7868416
Sundberg L and Cederberg A Penetration of clarithromycin and its 14-hydroxy metabolite into middle ear effusion in children with secretory otitis media. 1994 J. Antimicrob. Chemother. pmid:8182011
Cynamon MH et al. Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979270
Laing RB et al. New antimicrobials against Mycobacterium marinum infection. 1994 Br. J. Dermatol. pmid:7857853
Spiegl PV and Feiner CM Mycobacterium phlei infection of the foot: a case report. 1994 Foot Ankle Int pmid:7894643
Walker KJ et al. Evaluation of antimicrobial activities of clarithromycin and 14-hydroxyclarithromycin against three strains of Haemophilus influenzae by using an in vitro pharmacodynamic model. 1994 Antimicrob. Agents Chemother. pmid:7811010
Price DA et al. Clinical response to the addition of clarithromycin in Pneumocystis carinii pneumonia refractory to high dose co-trimoxazole. 1994 J. Antimicrob. Chemother. pmid:7814298
Tahara RW et al. The question of clarithromycin: a first-line drug for sinusitis? 1994 Arch Fam Med pmid:7818657
Pustorino S et al. [Effects of intravenous administration of clarithromycin on plasma levels of gastrin and group I pepsinogen]. 1994 Clin Ter pmid:7820984
Tessier MH et al. Clarithromycin for atypical mycobacterial lymphadenitis in non-immunocompromised children. 1994 Dec 24-31 Lancet pmid:7997032
Mor N et al. Accumulation of clarithromycin in macrophages infected with Mycobacterium avium. 1994 Jan-Feb Pharmacotherapy pmid:8159593
Winter J Intravenous clarithromycin. 1994 Mar 16-Apr 5 Br J Hosp Med pmid:8032567
Gersema LM et al. Suspected drug interaction between cyclosporine and clarithromycin. 1994 Mar-Apr J. Heart Lung Transplant. pmid:8031821
Heifets LB Quantitative cultures and drug susceptibility testing of Mycobacterium avium clinical isolates before and during the antimicrobial therapy. 1994 Mar-Apr Res. Microbiol. pmid:7809471
Dautzenberg B Clinical trials in Mycobacterium avium therapy: lessons to take home. 1994 Mar-Apr Res. Microbiol. pmid:7809472
Scaglione F et al. Effect of antibiotics on Bordetella pertussis adhering activity: hypothesis regarding mechanism of action. 1994 May-Jun Chemotherapy pmid:7515782
O'Connor NK and Fris J Clarithromycin-carbamazepine interaction in a clinical setting. 1994 Nov-Dec J Am Board Fam Pract pmid:7847111
Cama VA et al. Treatment of acute and chronic Cryptosporidium parvum infections in mice using clarithromycin and 14-OH clarithromycin. 1994 Sep-Oct J. Eukaryot. Microbiol. pmid:7804227
FDA approves Biaxin for MAC prophylaxis. Food and Drug Administration. 1995 J Int Assoc Physicians AIDS Care pmid:11363096
Odenholt-Tornqvist I et al. Postantibiotic effects and postantibiotic sub-MIC effects of roxithromycin, clarithromycin, and azithromycin on respiratory tract pathogens. 1995 Antimicrob. Agents Chemother. pmid:7695310
Ives DV et al. Impact of clarithromycin and azithromycin on patterns of treatment and survival among AIDS patients with disseminated Mycobacterium avium complex. 1995 AIDS pmid:7755914
Block S et al. Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate. 1995 Pediatr. Infect. Dis. J. pmid:7667050
Klapper SR et al. Atypical mycobacterial infection of the orbit. 1995 Ophthalmology pmid:9097803
Savarino V et al. What is the meaning of ranitidine in successful triple-therapy against Helicobacter pylori infection? 1995 Am. J. Gastroenterol. pmid:8540537
Gustavson LE et al. Effect of omeprazole on concentrations of clarithromycin in plasma and gastric tissue at steady state. 1995 Antimicrob. Agents Chemother. pmid:8540719
Ostroff SM et al. Preventing disseminated Mycobacterium avium complex disease in patients infected with human immunodeficiency virus. 1995 Clin. Infect. Dis. pmid:8547516
Odagiri S Levofloxacin in patients with severe respiratory tract infection. 1995 Drugs pmid:8549387
Logan RP et al. Eradication of Helicobacter pylori and prevention of recurrence of duodenal ulcer: a randomized, double-blind, multi-centre trial of omeprazole with or without clarithromycin. 1995 Aliment. Pharmacol. Ther. pmid:8527618
Lee D et al. Localized Mycobacterium avium-intracellulare mastitis in an immunocompetent woman with silicone breast implants. 1995 Plast. Reconstr. Surg. pmid:7809228
Gill CJ et al. In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin. 1995 J. Antibiot. pmid:7490222
Gelber RH Successful treatment of a lepromatous patient with clarithromycin. 1995 Int. J. Lepr. Other Mycobact. Dis. pmid:7730711
Adamek RJ et al. [Short-term triple therapy with pantoprazole, clarithromycin and metronidazole for the healing of Helicobacter pylori infection]. 1995 Dtsch. Med. Wochenschr. pmid:7889816
Spangler SK et al. Susceptibilities of 201 anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin by oxyrase agar dilution and E test methodologies. 1995 J. Clin. Microbiol. pmid:7615756
Schepp W [Omeprazole + clarithromycin + metronidazole--a new standard for eradication of Helicobacter pylori]. 1995 Z Gastroenterol pmid:7502558
Widgerow AD et al. Atypical Mycobacterium and breast surgery. 1995 Ann Plast Surg pmid:7486746
Tamaoki J et al. Effect of clarithromycin on sputum production and its rheological properties in chronic respiratory tract infections. 1995 Antimicrob. Agents Chemother. pmid:7486901
Mushatt DM and Witzig RS Successful treatment of Mycobacterium abscessus infections with multidrug regimens containing clarithromycin. 1995 Clin. Infect. Dis. pmid:7620048
Vance E et al. Pharmacokinetics of clarithromycin and zidovudine in patients with AIDS. 1995 Antimicrob. Agents Chemother. pmid:7574530
Singh N and Yu VL Clarithromycin therapy for Mycobacterium avium complex bacteremia. 1995 Ann. Intern. Med. pmid:7632282
Michałowska-Mitczuk D [Patients with chronic sputum positive tuberculosis-a therapeutic problem]. 1995 Pneumonol Alergol Pol pmid:7633360
Colizza DF Pertussis update. 1995 J Sch Health pmid:7637337
de Boer WA and Tytgat GN The best therapy for Helicobacter pylori infection: should efficacy or side-effect profile determine our choice? 1995 Scand. J. Gastroenterol. pmid:7638563
Takimoto T et al. Efficacy of lansoprazole in eradication of Helicobacter pylori. 1995 J. Clin. Gastroenterol. pmid:7594327
Shimoyama T et al. Eradication of Helicobacter pylori with lansoprazole and clarithromycin in gastric ulcer patients. 1995 J. Clin. Gastroenterol. pmid:7594328
Fukuda Y et al. Combination therapies with a proton pump inhibitor for Helicobacter pylori-infected gastric ulcer patients. 1995 J. Clin. Gastroenterol. pmid:7594330
Xu G et al. [Effect of clarithromycin on macrophage functions]. 1995 Kansenshogaku Zasshi pmid:7594777
Gelber RH et al. Activity of combinations of dapsone, rifampin, minocycline, clarithromycin, and sparfloxacin against M. leprae-infected mice. 1995 Int. J. Lepr. Other Mycobact. Dis. pmid:7602221
Milde P et al. Cutaneous bacillary angiomatosis in a patient with chronic lymphocytic leukemia. 1995 Arch Dermatol pmid:7543264
Nightingale SD et al. Clarithromycin-induced mania in two patients with AIDS. 1995 Clin. Infect. Dis. pmid:7548513
Matsiota-Bernard P et al. Mycobacterium genavense infection in a patient with AIDS who was successfully treated with clarithromycin. 1995 Clin. Infect. Dis. pmid:7548515
Citron DM et al. Activity of ampicillin/sulbactam, ticarcillin/clavulanate, clarithromycin, and eleven other antimicrobial agents against anaerobic bacteria isolated from infections in children. 1995 Clin. Infect. Dis. pmid:7548597
Ishii K et al. A new pharmacokinetic model including in vivo dissolution and gastrointestinal transit parameters. 1995 Biol. Pharm. Bull. pmid:7550125
Harris AW et al. Eradication of Helicobacter pylori with lansoprazole and clarithromycin. 1995 Aliment. Pharmacol. Ther. pmid:7605863
Tamaoki J et al. Effects of macrolide antibiotics on neurally mediated contraction of human isolated bronchus. 1995 J. Allergy Clin. Immunol. pmid:7722166
Conte JE et al. Intrapulmonary pharmacokinetics of clarithromycin and of erythromycin. 1995 Antimicrob. Agents Chemother. pmid:7726492
Lacassin F et al. Clarithromycin-minocycline combination as salvage therapy for toxoplasmosis in patients infected with human immunodeficiency virus. 1995 Antimicrob. Agents Chemother. pmid:7695324
Labenz J and Börsch G Toward an optimal treatment of Helicobacter pylori-positive peptic ulcers. 1995 Am. J. Gastroenterol. pmid:7733070
Forné M et al. Impact of colloidal bismuth subnitrate in the eradication rates of Helicobacter pylori infection-associated duodenal ulcer using a short treatment regimen with omeprazole and clarithromycin: a randomized study. 1995 Am. J. Gastroenterol. pmid:7733075
Metz DC and Getz HD Helicobacter pylori gastritis therapy with omeprazole and clarithromycin increases serum carbamazepine levels. 1995 Dig. Dis. Sci. pmid:7720489
Cahill RJ et al. Effect of eradication of Helicobacter pylori infection on gastric epithelial cell proliferation. 1995 Dig. Dis. Sci. pmid:7648960
Dautzenberg B et al. Clarithromycin in the treatment of Mycobacterium avium lung infections in patients without AIDS. Clarithromycin Study Group of France. 1995 Chest pmid:7705112
Schlossberg D Azithromycin and clarithromycin. 1995 Med. Clin. North Am. pmid:7791424
Gross RH et al. Corneal pharmacokinetics of topical clarithromycin. 1995 Invest. Ophthalmol. Vis. Sci. pmid:7706046
Frotz H et al. [Ranitidine and clarithromycin for eradication of Helicobacter pylori in patients with duodenal ulcer]. 1995 Arzneimittelforschung pmid:7710445
Luna-Herrera J et al. Antituberculosis activity of clarithromycin. 1995 Antimicrob. Agents Chemother. pmid:8593004
Ellis LC et al. Postantibiotic effect of clarithromycin alone and combined with ethambutol against Mycobacterium avium complex. 1995 Antimicrob. Agents Chemother. pmid:8593025
Truffot-Pernot C et al. Clarithromycin is inactive against Mycobacterium tuberculosis. 1995 Antimicrob. Agents Chemother. pmid:8593032
Schütze K and Hentschel E Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. 1995 Z Gastroenterol pmid:8600661
Tseng AL and Walmsley SL Rifabutin-associated uveitis. 1995 Ann Pharmacother pmid:8573961
Moayyedi P et al. Efficacy and optimum dose of omeprazole in a new 1-week triple therapy regimen to eradicate Helicobacter pylori. 1995 Eur J Gastroenterol Hepatol pmid:8574714
Fujioka T et al. Peptic ulcer recurrence after Helicobacter pylori eradication: a 5-year follow-up study. 1995 Eur J Gastroenterol Hepatol pmid:8574733
Rizzato G et al. Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia. 1995 Eur. Respir. J. pmid:7789484
Ford A et al. Clarithromycin-induced digoxin toxicity in a patient with AIDS. 1995 Clin. Infect. Dis. pmid:8645810
Gidoh M and Saito H [Present status of studies on antileprosy drugs]. 1995 Nihon Rai Gakkai Zasshi pmid:8582877
Stafstrom CE et al. Erythromycin-induced carbamazepine toxicity: a continuing problem. 1995 Arch Pediatr Adolesc Med pmid:7827672
Gioulekas J and Hall A Uveitis associated with rifabutin therapy. 1995 Aust N Z J Ophthalmol pmid:11980079
Reid R et al. Pneumococcal meningitis during therapy of otitis media with clarithromycin. 1995 Pediatr. Infect. Dis. J. pmid:8786899
Parasakthi N and Goh KL Primary and acquired resistance to clarithromycin among Helicobacter pylori strains in Malaysia. 1995 Am. J. Gastroenterol. pmid:7872306
Kadayifçi A et al. Low dose clarithromycin plus omeprazole eradicates Helicobacter pylori in duodenal ulcer disease. 1995 Am. J. Gastroenterol. pmid:7872307
Clarithromycin for MAC. 1995 AIDS Patient Care pmid:11361361
Wallace RJ et al. Reduced serum levels of clarithromycin in patients treated with multidrug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection. 1995 J. Infect. Dis. pmid:7876634
Moorthy RS and Rao NA Atypical mycobacterial wound infection after blepharoplasty. 1995 Br J Ophthalmol pmid:7880802
Yoshizawa A et al. [Legionella pneumonia diagnosed by urinary antigen detection]. 1995 Nihon Kyobu Shikkan Gakkai Zasshi pmid:7791279
Cheng B Preventing opportunistic infections. 1995 PI Perspect pmid:11362422
Lounis N et al. Selection of clarithromycin-resistant Mycobacterium avium complex during combined therapy using the beige mouse model. 1995 Antimicrob. Agents Chemother. pmid:7793860
Fattorini L et al. In vitro and ex vivo activities of antimicrobial agents used in combination with clarithromycin, with or without amikacin, against Mycobacterium avium. 1995 Antimicrob. Agents Chemother. pmid:7793873
Abbott files SNDA for MAC prophylaxis. 1995 J Int Assoc Physicians AIDS Care pmid:11362606
Cohen Y et al. Use of normal C57BL/6 mice with established Mycobacterium avium infections as an alternative model for evaluation of antibiotic activity. 1995 Antimicrob. Agents Chemother. pmid:7793882
Pierce M Another perspective on MAC prophylaxis. Interview by Gordon Nary. 1995 J Int Assoc Physicians AIDS Care pmid:11362746
Furney SK et al. Activities of rifabutin, clarithromycin, and ethambutol against two virulent strains of Mycobacterium avium in a mouse model. 1995 Antimicrob. Agents Chemother. pmid:7793895
Archange YR et al. Clarithromycin prophylaxis against disseminated Mycobacterium avium complex in patients with AIDS. 1995 J Int Assoc Physicians AIDS Care pmid:11362747
Brown BA et al. Clarithromycin-induced hepatotoxicity. 1995 Clin. Infect. Dis. pmid:7795060
Physician's aggressive preventive therapy differs. 1995 AIDS Alert pmid:11362774
Raffi F et al. Breakthrough cerebral toxoplasmosis in patients with AIDS who are being treated with clarithromycin. 1995 Clin. Infect. Dis. pmid:7795062
New drug applications sought. 1995 AIDS Alert pmid:11362777
Smart T Cryptosporidiosis at ICAAC. 1995 GMHC Treat Issues pmid:11362913
Sharma PK and Tami TA AIDS: lessons from the last decade and prospects for the future. 1995 Ear Nose Throat J pmid:7796740
Researchers find new drugs to fight MAC. 1995 AIDS Alert pmid:11362925