| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gram-Negative Bacterial Infections | D016905 | 16 associated lipids |
| Angiomatosis, Bacillary | D016917 | 2 associated lipids |
| Meningitis, Bacterial | D016920 | 6 associated lipids |
| Common Variable Immunodeficiency | D017074 | 4 associated lipids |
| AIDS-Related Opportunistic Infections | D017088 | 9 associated lipids |
| IgA Deficiency | D017098 | 2 associated lipids |
| Liver Failure, Acute | D017114 | 11 associated lipids |
| Skin Diseases, Bacterial | D017192 | 8 associated lipids |
| Dermatitis, Phototoxic | D017484 | 4 associated lipids |
| Pityriasis Rosea | D017515 | 3 associated lipids |
| Cutaneous Fistula | D017577 | 1 associated lipids |
| Kleine-Levin Syndrome | D017593 | 1 associated lipids |
| Periodontal Attachment Loss | D017622 | 7 associated lipids |
| Soft Tissue Injuries | D017695 | 2 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Cytomegalovirus Retinitis | D017726 | 2 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Cardiovascular Abnormalities | D018376 | 2 associated lipids |
| Pneumonia, Bacterial | D018410 | 16 associated lipids |
| Soft Tissue Infections | D018461 | 2 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Cryptogenic Organizing Pneumonia | D018549 | 3 associated lipids |
| Carcinoma, Lewis Lung | D018827 | 22 associated lipids |
| Gingival Overgrowth | D019214 | 7 associated lipids |
| Tooth, Nonvital | D019553 | 2 associated lipids |
| alpha 1-Antitrypsin Deficiency | D019896 | 3 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Central Nervous System Protozoal Infections | D020808 | 3 associated lipids |
| Epilepsy, Partial, Motor | D020938 | 1 associated lipids |
| Chlamydophila Infections | D023521 | 4 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Renal Insufficiency | D051437 | 8 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Buruli Ulcer | D054312 | 1 associated lipids |
| Extensively Drug-Resistant Tuberculosis | D054908 | 1 associated lipids |
| Leprosy, Paucibacillary | D056005 | 2 associated lipids |
| Upper Extremity Deep Vein Thrombosis | D056824 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Sacroiliitis | D058566 | 1 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Miftahussurur M et al. | Surveillance of Helicobacter pylori Antibiotic Susceptibility in Indonesia: Different Resistance Types among Regions and with Novel Genetic Mutations. | 2016 | PLoS ONE | pmid:27906990 |
| Velu PP et al. | Pulmonary Mycobacterium marinum infection: 'fish tank granuloma' of the lung. | 2016 | Scott Med J | pmid:27872397 |
| Noh HM et al. | Eradication Rate by Duration of Third-line Rescue Therapy with Levofloxacin after Helicobacter pylori Treatment Failure in Clinical Practice. | 2016 | Korean J Gastroenterol | pmid:27871162 |
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
| Fan W et al. | An unusual case of folliculitis spinulosa decalvans. | 2016 | Cutis | pmid:27814407 |
| Miftahussurur M et al. | Emerging Helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal. | 2016 | BMC Microbiol. | pmid:27809767 |
| Sancak S et al. | Intestinal blood flow by Doppler ultrasound: the impact of clarithromycin treatment for feeding intolerance in preterm neonates. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26135789 |
| Uehara H et al. | Comparison of the Anti-angiogenic and Anti-inflammatory Effects of Two Antibiotics: Clarithromycin Versus Moxifloxacin. | 2016 | Curr. Eye Res. | pmid:26125497 |
| Ohe M et al. | A case of lupus nephritis treated with clarithromycin, tacrolimus, and glucocorticoids. | 2016 | Kaohsiung J. Med. Sci. | pmid:27638410 |
| Phaw NA and Tsai HH | Eosinophilic gastroenteritis: a challenge to diagnose and treat. | 2016 | BMJ Case Rep | pmid:27613263 |
| Plate A | [Not Available]. | 2016 | Praxis (Bern 1994) | pmid:27606919 |
| Huh CW et al. | Early Attempts to Eradicate Helicobacter pylori after Endoscopic Resection of Gastric Neoplasm Significantly Improve Eradication Success Rates. | 2016 | PLoS ONE | pmid:27588679 |
| Watanabe M et al. | Saturated fatty acids and fatty acid esters promote the polymorphic transition of clarithromycin metastable form I crystal. | 2016 | Int J Pharm | pmid:27553780 |
| Cosme A et al. | Antimicrobial Susceptibility-Guided Therapy Versus Empirical Concomitant Therapy for Eradication of Helicobacter pylori in a Region with High Rate of Clarithromycin Resistance. | 2016 | Helicobacter | pmid:25982426 |
| Inagaki K et al. | Successful Treatment of Peritoneal Dialysis-related Peritonitis due to Mycobacterium iranicum. | 2016 | Intern. Med. | pmid:27432106 |
| Shiratori S et al. | Two Cases of Chronic Gastritis with non-Helicobacter pylori Helicobacter Infection. | 2016 | Intern. Med. | pmid:27432094 |
| Furuta K et al. | 18 Cases of pulmonary Mycobacterium abscessus: Clinical difference depending on the presence or absence of Mycobacterium avium complex. | 2016 | J. Infect. Chemother. | pmid:27430867 |
| Zemali N et al. | Helicobacter pylori resistance to clarithromycin in Reunion Island. | 2016 | Med Mal Infect | pmid:27427280 |
| Ozeki K et al. | Association of Hay Fever with the Failure of Helicobacter pylori Primary Eradication. | 2016 | Intern. Med. | pmid:27374672 |
| Campillo A et al. | [Cuadruple concomitant non-bismuth therapy vs. classical triple therapy as first line therapy for Helicobacter pylori infection]. | 2016 | Med Clin (Barc) | pmid:27374029 |
| Khashei R et al. | High rate of A2142G point mutation associated with clarithromycin resistance among Iranian Helicobacter pylori clinical isolates. | 2016 | APMIS | pmid:27357065 |
| Alarcón-Millán J et al. | Clarithromycin resistance and prevalence of Helicobacter pylori virulent genotypes in patients from Southern México with chronic gastritis. | 2016 | Infect. Genet. Evol. | pmid:27355861 |
| Khonche A et al. | Adjunctive Therapy with Curcumin for Peptic Ulcer: a Randomized Controlled Trial. | 2016 | Drug Res (Stuttg) | pmid:27351245 |
| Büchsel M et al. | A case of septic arthritis caused by a Mycoplasma salivarium strain resistant towards Ciprofloxacin and Clarithromycin in a patient with chronic lymphatic leukemia. | 2016 | Diagn. Microbiol. Infect. Dis. | pmid:27342785 |
| Lin LC et al. | Nonbismuth concomitant quadruple therapy for Helicobacter pylori eradication in Chinese regions: A meta-analysis of randomized controlled trials. | 2016 | World J. Gastroenterol. | pmid:27340362 |
| Garcia de Carvalho NF et al. | Resazurin Microtiter Assay for Clarithromycin Susceptibility Testing of Clinical Isolates of Mycobacterium abscessus Group. | 2016 | J. Clin. Lab. Anal. | pmid:27169515 |
| Schuster S et al. | Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrB. | 2016 | Antimicrob. Agents Chemother. | pmid:27161641 |
| Oberhofer E | [Quadruple therapy is more effective against H. pylori]. | 2016 | MMW Fortschr Med | pmid:27155683 |
| Mayor S | Short term increase in neuropsychiatric events is seen with H pylori treatment containing clarithromycin. | 2016 | BMJ | pmid:27143325 |
| Shokri-Shirvani J et al. | Letter: global emergence of Helicobacter pylori antibiotic resistance - unanswered questions. | 2016 | Aliment. Pharmacol. Ther. | pmid:27137738 |
| Wong AY et al. | Association Between Acute Neuropsychiatric Events and Helicobacter pylori Therapy Containing Clarithromycin. | 2016 | JAMA Intern Med | pmid:27136661 |
| Zollner-Schwetz I et al. | Primary resistance of Helicobacter pylori is still low in Southern Austria. | 2016 | Int. J. Med. Microbiol. | pmid:27134190 |
| Georgopoulos SD et al. | Randomized clinical trial comparing ten day concomitant and sequential therapies for Helicobacter pylori eradication in a high clarithromycin resistance area. | 2016 | Eur. J. Intern. Med. | pmid:27134145 |
| Li M et al. | Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. | 2016 | Int J Mol Sci | pmid:27669217 |
| Dubini M et al. | Multiple drug allergy: A case of anaphylaxis to levofloxacin but tolerance to ciprofloxacin. | 2016 | Ann. Allergy Asthma Immunol. | pmid:27009438 |
| Miyashita N et al. | Macrolide Therapy for Prevention of Exacerbation in Individuals with Diffuse Aspiration Bronchiolitis. | 2016 | J Am Geriatr Soc | pmid:27000351 |
| Shichijo S et al. | Histologic intestinal metaplasia and endoscopic atrophy are predictors of gastric cancer development after Helicobacter pylori eradication. | 2016 | Gastrointest. Endosc. | pmid:26995689 |
| Radzikowska E et al. | Cryptogenic Organizing Pneumonia: IL-1β, IL-6, IL-8, and TGF- β1 Serum Concentrations and Response to Clarithromycin Treatment. | 2016 | Adv. Exp. Med. Biol. | pmid:26987326 |
| Wu DC et al. | A Pilot Randomized Controlled Study of Dexlansoprazole MR-Based Triple Therapy for Helicobacter Pylori Infection. | 2016 | Medicine (Baltimore) | pmid:26986096 |
| Swaminathan A et al. | Treating children for drug-resistant tuberculosis in Tajikistan with Group 5 medications. | 2016 | Int. J. Tuberc. Lung Dis. | pmid:26970156 |
| Wong IC | Author's reply to Blake. | 2016 | BMJ | pmid:26957514 |
| Todo K et al. | Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female. | 2016 | Ann. Hematol. | pmid:26957356 |
| Iyer G and Alexander GC | Editorialists' reply to Blake. | 2016 | BMJ | pmid:26957321 |
| Blake Z | Study provides insufficient evidence of a link between clarithromycin and myocardial infarction. | 2016 | BMJ | pmid:26955978 |
| Seyama S et al. | Clarithromycin Resistance Mechanisms of Epidemic β-Lactamase-Nonproducing Ampicillin-Resistant Haemophilus influenzae Strains in Japan. | 2016 | Antimicrob. Agents Chemother. | pmid:26953210 |
| Ji Z et al. | The Association of Age and Antibiotic Resistance of Helicobacter Pylori: A Study in Jiaxing City, Zhejiang Province, China. | 2016 | Medicine (Baltimore) | pmid:26937912 |
| Murakami K et al. | Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study. | 2016 | Gut | pmid:26935876 |
| Kadota T et al. | Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease. | 2016 | BMC Infect. Dis. | pmid:26818764 |
| Gaüzère BA and Malvy D | [Vingt-cinquième réunion du comité local de la Société de pathologie exotique, 24 novembre 2015]. | 2016 | Bull Soc Pathol Exot | pmid:26818816 |
| Tebruegge M et al. | Nontuberculous Mycobacterial Disease in Children - Epidemiology, Diagnosis & Management at a Tertiary Center. | 2016 | PLoS ONE | pmid:26812154 |
| Fralick M et al. | Bleeding associated with coadministration of rivaroxaban and clarithromycin. | 2016 | CMAJ | pmid:26811362 |
| Berlin S et al. | Pharmacokinetics and Pulmonary Distribution of Clarithromycin and Rifampicin after Concomitant and Consecutive Administration in Foals. | 2016 | Mol. Pharm. | pmid:26808255 |
| Sun H et al. | [Antimicrobial susceptibility of community-acquired respiratory tract pathogens isolated from class B hospitals in China during 2013 and 2014]. | 2016 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:26792053 |
| Miglietta F et al. | A rare case of Saprochaete capitata fungemia in a critical ill patient without hematologic and oncological disorders. | 2016 | Rev Esp Quimioter | pmid:26785226 |
| Raymond J et al. | Diagnosis of Helicobacter pylori recurrence: relapse or reinfection? Usefulness of molecular tools. | 2016 | Scand. J. Gastroenterol. | pmid:26784882 |
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| Iyer G and Alexander GC | Cardiovascular risks associated with clarithromycin. | 2016 | BMJ | pmid:26769796 |
| Wong AY et al. | Cardiovascular outcomes associated with use of clarithromycin: population based study. | 2016 | BMJ | pmid:26768836 |
| Villain J et al. | Acute toxicities of pharmaceuticals toward green algae. mode of action, biopharmaceutical drug disposition classification system and quantile regression models. | 2016 | Ecotoxicol. Environ. Saf. | pmid:26590695 |
| Geng S et al. | Clarithromycin ion pair in a liposomal membrane to improve its stability and reduce its irritation caused by intravenous administration. | 2016 | Expert Opin Drug Deliv | pmid:26588710 |
| Eszik I et al. | High dynamic range detection of Chlamydia trachomatis growth by direct quantitative PCR of the infected cells. | 2016 | J. Microbiol. Methods | pmid:26578244 |
| Jain SK et al. | Lectin-Conjugated Clarithromycin and Acetohydroxamic Acid-Loaded PLGA Nanoparticles: a Novel Approach for Effective Treatment of H. pylori. | 2016 | AAPS PharmSciTech | pmid:26566630 |
| Di Giulio M et al. | In vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in Central Italy. | 2016 | Scand. J. Gastroenterol. | pmid:26554617 |
| Djennane-Hadibi F et al. | High-Level Primary Clarithromycin Resistance of Helicobacter pylori in Algiers, Algeria: A Prospective Multicenter Molecular Study. | 2016 | Microb. Drug Resist. | pmid:26554340 |
| Chen CH et al. | Mycobacterium abscessus complex bacteremia due to prostatitis after prostate biopsy. | 2016 | Indian J Tuberc | pmid:27998503 |
| Gehlot V et al. | Low prevalence of clarithromycin-resistant Helicobacter pylori isolates with A2143G point mutation in the 23S rRNA gene in North India. | 2016 | J Glob Antimicrob Resist | pmid:27530837 |
| Xuan SH et al. | Detection of clarithromycin-resistant Helicobacter pylori in clinical specimens by molecular methods: A review. | 2016 | J Glob Antimicrob Resist | pmid:27436390 |
| Siddiqui TR et al. | Emerging trends of antimicrobial resistance in Helicobacter pylori isolates obtained from Pakistani patients: The need for consideration of amoxicillin and clarithromycin. | 2016 | J Pak Med Assoc | pmid:27339574 |
| Boyanova L et al. | Helicobacter pylori resistance to six antibiotics by two breakpoint systems and resistance evolution in Bulgaria. | 2016 | Infect Dis (Lond) | pmid:26465202 |
| Lahmer T et al. | Pseudallescheria boydii with Aspergillus fumigatus and Aspergillus terreus in a Critically Ill Hematopoietic Stem Cell Recipient with ARDS. | 2016 | Mycopathologia | pmid:26455910 |
| Lee J et al. | A new antibiotic regimen treats and prevents intra-amniotic inflammation/infection in patients with preterm PROM. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26441216 |
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| Graham DY and Gisbert JP | Letter: clarithromycin dose for H. pylori therapy remains unresolved. | 2015 | Aliment. Pharmacol. Ther. | pmid:26238583 |
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