clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Gram-Negative Bacterial Infections D016905 16 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Meningitis, Bacterial D016920 6 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
IgA Deficiency D017098 2 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Cutaneous Fistula D017577 1 associated lipids
Kleine-Levin Syndrome D017593 1 associated lipids
Periodontal Attachment Loss D017622 7 associated lipids
Soft Tissue Injuries D017695 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Cytomegalovirus Retinitis D017726 2 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Cardiovascular Abnormalities D018376 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Soft Tissue Infections D018461 2 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Cryptogenic Organizing Pneumonia D018549 3 associated lipids
Carcinoma, Lewis Lung D018827 22 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Tooth, Nonvital D019553 2 associated lipids
alpha 1-Antitrypsin Deficiency D019896 3 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Epilepsy, Partial, Motor D020938 1 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Renal Insufficiency D051437 8 associated lipids
Immune Reconstitution Inflammatory Syndrome D054019 1 associated lipids
Buruli Ulcer D054312 1 associated lipids
Extensively Drug-Resistant Tuberculosis D054908 1 associated lipids
Leprosy, Paucibacillary D056005 2 associated lipids
Upper Extremity Deep Vein Thrombosis D056824 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Plaque, Atherosclerotic D058226 7 associated lipids
Sacroiliitis D058566 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Walrave TR et al. [Mania induced by antibiotic therapy]. Tijdschr Psychiatr pmid:27527887
Set R and Shastri J Laboratory aspects of clinically significant rapidly growing mycobacteria. Indian J Med Microbiol pmid:22120792
Mégraud F [Helicobacter pylori infection: Review and practice]. Presse Med pmid:20627443
Vicente R et al. [Helicobacter pylori eradication in patients with peptic ulcer after two treatment failures: a prospective culture-guided study]. Gastroenterol Hepatol pmid:12139836
Yoon HJ et al. Nontuberculous mycobacterial tenosynovitis in the hand: two case reports with the MR imaging findings. Korean J Radiol pmid:22043158
Bennie CJ et al. In vitro interaction of some drug combinations to inhibit rapidly growing mycobacteria isolates from cats and dogs and these isolates' susceptibility to cefovecin and clofazimine. Aust. Vet. J. pmid:25622709
Horiguchi T et al. Antibacterial activity and clinical efficacy of sparfloxacin in Mycobacterium avium-intracellulare complex infection. J. Int. Med. Res. pmid:15458286
Solé López J et al. [Consumption of antibiotics and their possible relationship with bacterial resistance in the "Costa de Ponent" health region: analysis of evolution through the initial and end periods of the last decade]. Aten Primaria pmid:15274900
Lew EA Clarithromycin, lansoprazole, and metronidazole eradicated Helicobacter pylori infection in chronic renal insufficiency. ACP J. Club pmid:15122860
Lindeboom JA Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria. Pediatr Dermatol pmid:26823205
Beck J Efficacy of esomeprazole in patients with acid-peptic disorders. Gastroenterol Nurs pmid:15082946
pmid:
Alboraie M et al. Quadruple therapy versus standard triple therapy for eradication of Helicobacter pylori in Kuwait. Arab J Gastroenterol pmid:26611765
Gościniak G et al. Frequency of infection with Helicobacter pylori isolates of different antimicrobial profiles in children and adolescents: A preliminary study. Adv Clin Exp Med pmid:28791844
Sambourg E et al. [Paradoxical reactions and responses during antibiotic treatment for Mycobacterium ulcerans infection (Buruli ulcer). Four cases from French Guiana]. Ann Dermatol Venereol pmid:24951139
Dupin N [Paradoxal cultures]. Ann Dermatol Venereol pmid:24951138
Rush R and Sheth S Fulminant toxoplasmic retinochoroiditis following intravitreal triamcinolone administration. Indian J Ophthalmol pmid:22446913
Seitz CS et al. Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. Allergol Immunopathol (Madr) pmid:21269750
Moreira A et al. Is Helicobacter pylori infection associated with chronic idiopathic urticaria? Allergol Immunopathol (Madr) pmid:12890412
Cobos-Trigueros N et al. [Macrolides and ketolides]. Enferm. Infecc. Microbiol. Clin. pmid:19625112