| MeSH term | MeSH ID | Detail |
|---|---|---|
| Gram-Negative Bacterial Infections | D016905 | 16 associated lipids |
| Angiomatosis, Bacillary | D016917 | 2 associated lipids |
| Meningitis, Bacterial | D016920 | 6 associated lipids |
| Common Variable Immunodeficiency | D017074 | 4 associated lipids |
| AIDS-Related Opportunistic Infections | D017088 | 9 associated lipids |
| IgA Deficiency | D017098 | 2 associated lipids |
| Liver Failure, Acute | D017114 | 11 associated lipids |
| Skin Diseases, Bacterial | D017192 | 8 associated lipids |
| Dermatitis, Phototoxic | D017484 | 4 associated lipids |
| Pityriasis Rosea | D017515 | 3 associated lipids |
| Cutaneous Fistula | D017577 | 1 associated lipids |
| Kleine-Levin Syndrome | D017593 | 1 associated lipids |
| Periodontal Attachment Loss | D017622 | 7 associated lipids |
| Soft Tissue Injuries | D017695 | 2 associated lipids |
| Community-Acquired Infections | D017714 | 8 associated lipids |
| Cytomegalovirus Retinitis | D017726 | 2 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Cardiovascular Abnormalities | D018376 | 2 associated lipids |
| Pneumonia, Bacterial | D018410 | 16 associated lipids |
| Soft Tissue Infections | D018461 | 2 associated lipids |
| Ventricular Dysfunction, Left | D018487 | 33 associated lipids |
| Cryptogenic Organizing Pneumonia | D018549 | 3 associated lipids |
| Carcinoma, Lewis Lung | D018827 | 22 associated lipids |
| Gingival Overgrowth | D019214 | 7 associated lipids |
| Tooth, Nonvital | D019553 | 2 associated lipids |
| alpha 1-Antitrypsin Deficiency | D019896 | 3 associated lipids |
| Genetic Predisposition to Disease | D020022 | 24 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Central Nervous System Protozoal Infections | D020808 | 3 associated lipids |
| Epilepsy, Partial, Motor | D020938 | 1 associated lipids |
| Chlamydophila Infections | D023521 | 4 associated lipids |
| Desulfovibrionaceae Infections | D045824 | 5 associated lipids |
| Renal Insufficiency | D051437 | 8 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Buruli Ulcer | D054312 | 1 associated lipids |
| Extensively Drug-Resistant Tuberculosis | D054908 | 1 associated lipids |
| Leprosy, Paucibacillary | D056005 | 2 associated lipids |
| Upper Extremity Deep Vein Thrombosis | D056824 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Sacroiliitis | D058566 | 1 associated lipids |
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Hanson KE et al. | Rapid molecular detection of inducible macrolide resistance in Mycobacterium chelonae and M. abscessus strains: a replacement for 14-day susceptibility testing? | 2014 | J. Clin. Microbiol. | pmid:24554745 |
| Almeida N et al. | Triple therapy with high-dose proton-pump inhibitor, amoxicillin, and doxycycline is useless for Helicobacter pylori eradication: a proof-of-concept study. | 2014 | Helicobacter | pmid:24506175 |
| Lara-MartÃn PA et al. | Occurrence, distribution and partitioning of nonionic surfactants and pharmaceuticals in the urbanized Long Island Sound Estuary (NY). | 2014 | Mar. Pollut. Bull. | pmid:24467856 |
| Markert C et al. | Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers. | 2014 | Br J Clin Pharmacol | pmid:23738582 |
| Furuta T et al. | Effect of dosing schemes of amoxicillin on eradication rates of Helicobacter pylori with amoxicillin-based triple therapy. | 2014 | J Clin Pharmacol | pmid:24122836 |
| Ratzinger F et al. | Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity. | 2014 | Sci Rep | pmid:25500904 |
| Shahbazi Niaz M et al. | Investigation into physical-chemical variables affecting the manufacture and dissolution of wet-milled clarithromycin nanoparticles. | 2014 | Pharm Dev Technol | pmid:24093825 |
| Trotti LM et al. | Improvement in daytime sleepiness with clarithromycin in patients with GABA-related hypersomnia: Clinical experience. | 2014 | J. Psychopharmacol. (Oxford) | pmid:24306133 |
| Nie W et al. | [The analysis of species identification and susceptibility testing of Mycobacterium abscessus]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262693 |
| Campanale M et al. | Nickel free-diet enhances the Helicobacter pylori eradication rate: a pilot study. | 2014 | Dig. Dis. Sci. | pmid:24595654 |
| Schuhfried G et al. | Gilles de la Tourette Syndrome caused by Mycoplasma pneumoniae successfully treated with macrolides. | 2014 | Klin Padiatr | pmid:25153913 |
| Svanström H et al. | Use of clarithromycin and roxithromycin and risk of cardiac death: cohort study. | 2014 | BMJ | pmid:25139799 |
| Giamarellos-Bourboulis EJ et al. | Effect of clarithromycin in patients with suspected Gram-negative sepsis: results of a randomized controlled trial. | 2014 | J. Antimicrob. Chemother. | pmid:24292991 |
| Zhao Y and Hu ZY | Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate. | 2014 | Br. J. Pharmacol. | pmid:24283665 |
| Harvey E and Varatharaj A | Round pneumonia. | 2014 | QJM | pmid:23708793 |
| Tsovolou EC et al. | Effect of clarithromycin in experimental empyema by multidrug-resistant Pseudomonas aeruginosa. | 2014 | APMIS | pmid:23656439 |
| Oztürk K et al. | Diagnosis of helicobacter pylori infection. | 2014 | Turk J Gastroenterol | pmid:25141328 |
| Pathak V et al. | Macrolide use leads to clinical and radiological improvement in patients with cryptogenic organizing pneumonia. | 2014 | Ann Am Thorac Soc | pmid:24460438 |
| Wu JY et al. | Evidence-based recommendations for successful Helicobacter pylori treatment. | 2014 | Expert Rev Gastroenterol Hepatol | pmid:24410470 |
| Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
| DÃaz Cuevas Z et al. | [Nodular skin lesions in a patient with rheumatoid arthritis under therapy with anti-tumor necrosis factor-α]. | 2014 | Med Clin (Barc) | pmid:23877097 |
| Jung YS et al. | [Trends in the eradication rates of Helicobacter pylori infection in Daegu and Gyeongsangbuk-do, Korea: multicenter study over 13 years]. | 2014 | Korean J Gastroenterol | pmid:24561694 |
| Vanderpas J et al. | Follow-up of Helicobacter pylori infection in children over two decades (1988-2007): persistence, relapse and acquisition rates. | 2014 | Epidemiol. Infect. | pmid:23809783 |
| Koh S et al. | Visualization of the meibomian glands by means of noncontact mobile-type meibography (Meibopen) in a 16-year-old girl with unilateral marginal staphylococcal keratitis. | 2014 | J AAPOS | pmid:24568999 |
| Ke AB et al. | Itraconazole and clarithromycin as ketoconazole alternatives for clinical CYP3A inhibition studies. | 2014 | Clin. Pharmacol. Ther. | pmid:24747234 |
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| Gisbert JP et al. | Third-line rescue therapy with bismuth-containing quadruple regimen after failure of two treatments (with clarithromycin and levofloxacin) for H. pylori infection. | 2014 | Dig. Dis. Sci. | pmid:24126798 |
| Maurer FP et al. | Erm(41)-dependent inducible resistance to azithromycin and clarithromycin in clinical isolates of Mycobacterium abscessus. | 2014 | J. Antimicrob. Chemother. | pmid:24500188 |
| Tranos P et al. | Bilateral diffuse iris atrophy after the use of oral clarithromycin. | 2014 | Cutan Ocul Toxicol | pmid:23763291 |
| Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
| Page SR and Yee KC | Rhabdomyolysis in association with simvastatin and dosage increment in clarithromycin. | 2014 | Intern Med J | pmid:25041770 |
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| Ghrew MH et al. | Successful renal transplant in patient with controlled pulmonary non-tuberculous mycobacterium infection. | 2014 | Libyan J Med | pmid:25249307 |
| Higgins JW et al. | Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1. | 2014 | Drug Metab. Dispos. | pmid:25106415 |
| Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
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| Peng YC et al. | Clarithromycin modulates Helicobacter pylori-induced activation of nuclear factor-κB through classical and alternative pathways in gastric epithelial cells. | 2014 | Clin. Exp. Med. | pmid:23129507 |
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| Lebedeva MV et al. | Clarithromycin as a chiral selector for enantioseparation of basic compounds in nonaqueous capillary electrophoresis. | 2014 | Electrophoresis | pmid:25100556 |
| Katayama M et al. | Preliminary study of interaction of clarithromycin with tacrolimus in cats. | 2014 | J. Vet. Med. Sci. | pmid:25099737 |
| Park CS et al. | Pretreatment antimicrobial susceptibility-guided vs. clarithromycin-based triple therapy for Helicobacter pylori eradication in a region with high rates of multiple drug resistance. | 2014 | Am. J. Gastroenterol. | pmid:25091062 |
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| Acosta CP et al. | [Determination of single nucleotide mutations in the 23S rRNA gene of Helicobacter pylori related to clarithromycin resistance in a population from Cauca, Colombia]. | 2014 | Biomedica | pmid:24968047 |
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| Petitto J et al. | Successful clarithromycin desensitization in a macrolide-sensitive pediatric patient. | 2013 May-Jun | J Allergy Clin Immunol Pract | pmid:24565493 |
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