clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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[Experience with treatment of chronic polypoid rhinosinusitis using low doses of clarithromycin in the postoperative period]. | 2012 | Vestn. Otorinolaringol. | pmid:22678641 | |
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Lotfy HM and Abdel-Monem Hagazy M | Comparative study of novel spectrophotometric methods manipulating ratio spectra: an application on pharmaceutical ternary mixture of omeprazole, tinidazole and clarithromycin. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22683662 |
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Chung JW et al. | Ten-day sequential versus triple therapy for Helicobacter pylori eradication: a prospective, open-label, randomized trial. | 2012 | J. Gastroenterol. Hepatol. | pmid:22849546 |
Chan A et al. | A case of wrist tenosynovitis caused by Mycobacterium kansasii in a renal transplant recipient. | 2012 | Transpl Infect Dis | pmid:22822725 |
Kanazu T et al. | Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. | 2012 | Biopharm Drug Dispos | pmid:22447511 |
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Gao M et al. | The effects of transrectal radiofrequency hyperthermia on patients with chronic prostatitis and the changes of MDA, NO, SOD, and Zn levels in pretreatment and posttreatment. | 2012 | Urology | pmid:22100490 |
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Saito R et al. | Molecular mechanism of macrolide-lincosamide resistance in Moraxella catarrhalis. | 2012 | J. Med. Microbiol. | pmid:22820696 |
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Kuo CH et al. | The Optimal First-Line Therapy of Helicobacter pylori Infection in Year 2012. | 2012 | Gastroenterol Res Pract | pmid:22792095 |
Marzouk H et al. | The utility of nasopharyngeal culture in the management of chronic adenoiditis. | 2012 | Int. J. Pediatr. Otorhinolaryngol. | pmid:22784508 |
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Sakinc T et al. | Influence of a 23S ribosomal RNA mutation in Helicobacter pylori strains on the in vitro synergistic effect of clarithromycin and amoxicillin. | 2012 | BMC Res Notes | pmid:23110798 |
Dore MP et al. | Efficacy of a "Rescue" Ciprofloxacin-Based Regimen for Eradication of Helicobacter pylori Infection after Treatment Failures. | 2012 | Gastroenterol Res Pract | pmid:22666234 |
Lange JN et al. | Sensitivity of human strains of Oxalobacter formigenes to commonly prescribed antibiotics. | 2012 | Urology | pmid:22656407 |
Robinson P et al. | Clarithromycin therapy for patients with cystic fibrosis: a randomized controlled trial. | 2012 | Pediatr. Pulmonol. | pmid:22266895 |
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