clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rodvold KA et al. | Intrapulmonary steady-state concentrations of clarithromycin and azithromycin in healthy adult volunteers. | 1997 | Antimicrob. Agents Chemother. | pmid:9174209 |
| Marignani M et al. | Reversal of long-standing iron deficiency anaemia after eradication of Helicobacter pylori infection. | 1997 | Scand. J. Gastroenterol. | pmid:9200297 |
| Kato S et al. | Omeprazole-based dual and triple regimens for Helicobacter pylori eradication in children. | 1997 | Pediatrics | pmid:9200377 |
| Gisbert JP et al. | [What is the current role of clarithromycin in the eradication of Helicobacter pylori?]. | 1997 | Rev Esp Enferm Dig | pmid:9221019 |
| Matsumoto T et al. | Regression of mucosa-associated lymphoid-tissue lymphoma of rectum after eradication of Helicobacter pylori. | 1997 | Lancet | pmid:9228971 |
| Kadayifçi A et al. | Clarithromycin-induced fever in a patient with Helicobacter pylori gastritis. | 1997 | Ann Pharmacother | pmid:9184727 |
| Götz JM et al. | Treatment of Helicobacter pylori infection favourably affects gastric mucosal superoxide dismutases. | 1997 | Gut | pmid:9203935 |
| Katari SR et al. | Clinical features of acute reversible tacrolimus (FK 506) nephrotoxicity in kidney transplant recipients. | 1997 | Clin Transplant | pmid:9193849 |
| Verhaegen J et al. | Impredictable susceptibility for cephalosporins in penicillin resistant Streptococcus pneumoniae. | 1997 | Acta Clin Belg | pmid:9204588 |
| Kim MJ et al. | Serum 13C-bicarbonate assay for the diagnosis of gastric Helicobacter pylori infection and response to treatment. | 1997 | Gastroenterology | pmid:9207259 |
| Waites K et al. | In vitro activities of oral antimicrobial agents against penicillin-resistant Streptococcus pneumoniae: implications for outpatient treatment. | 1997 | South. Med. J. | pmid:9191739 |
| Gotoh A et al. | Susceptibility of Helicobacter pylori isolates against agents commonly administered for eradication therapy and the efficacy of chemotherapy. | 1997 | Microbiol. Immunol. | pmid:9087962 |
| Driscoll MS and Tyring SK | Development of resistance to clarithromycin after treatment of cutaneous Mycobacterium chelonae infection. | 1997 | J. Am. Acad. Dermatol. | pmid:9091495 |
| Gui GP et al. | Two-year-outcomes analysis of Crohn's disease treated with rifabutin and macrolide antibiotics. | 1997 | J. Antimicrob. Chemother. | pmid:9096189 |
| Hoogkamp-Korstanje JA et al. | Multicentre in-vitro evaluation of the susceptibility of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis to ciprofloxacin, clarithromycin, co-amoxiclav and sparfloxacin. | 1997 | J. Antimicrob. Chemother. | pmid:9096192 |
| Stone GG et al. | PCR-RFLP typing of ureC from Helicobacter pylori isolated in Argentina from gastric biopsies before and after treatment with clarithromycin. | 1997 | Epidemiol. Infect. | pmid:9129588 |
| Spicer ST et al. | The mechanism of cyclosporine toxicity induced by clarithromycin. | 1997 | Br J Clin Pharmacol | pmid:9131953 |
| Guillemet C et al. | [Clarithromycin-digoxin: an unrecognized interaction in some patients]. | 1997 | Presse Med | pmid:9137381 |
| Nightingale CH | Pharmacokinetics and pharmacodynamics of newer macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109156 |
| Block SL | Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109158 |
| Tarlow MJ et al. | Future indications for macrolides. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109159 |
| Arguedas A et al. | Comparative trial of 3 days of azithromycin versus 10 days of clarithromycin in the treatment of children with acute otitis media with effusion. | 1997 | J Chemother | pmid:9106017 |
| Yanagihara K et al. | Effect of clarithromycin on lymphocytes in chronic respiratory Pseudomonas aeruginosa infection. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9001333 |
| Gan VN et al. | Penetration of clarithromycin into middle ear fluid of children with acute otitis media. | 1997 | Pediatr. Infect. Dis. J. | pmid:9002099 |
| Shortridge VD et al. | Molecular typing of Helicobacter pylori isolates from a multicenter U.S. clinical trial by ureC restriction fragment length polymorphism. | 1997 | J. Clin. Microbiol. | pmid:9003618 |
| Denys A | [Theoretical basis for the antibiotic therapy of the upper part of the respiratory system]. | 1997 | Otolaryngol Pol | pmid:9757681 |
| Kubas G and Gospodarek T | [The use of clarithromycin and amoxycillin in pediatric acute otitis media]. | 1997 | Otolaryngol Pol | pmid:9757683 |
| Burman WJ et al. | A retrospective comparison of clarithromycin versus rifampin in combination treatment for disseminated Mycobacterium avium complex disease in AIDS: clarithromycin decreases transfusion requirements. | 1997 | Int. J. Tuberc. Lung Dis. | pmid:9441082 |
| Suzuki K et al. | Activity of KRM 1648 or rifabutin alone or in combination with clarithromycin against Mycobacterium avium complex in human alveolar macrophages. | 1997 | Int. J. Tuberc. Lung Dis. | pmid:9441102 |
| Gotoh A et al. | Interaction of drugs for eradication therapy against antibiotic-resistant strains of Helicobacter pylori. | 1997 | Microbiol. Immunol. | pmid:9444328 |
| Prattichizzo FA et al. | [Carditis associated with Mycoplasma pneumoniae infection. Clinical aspects and therapeutic problems]. | 1997 | Minerva Cardioangiol | pmid:9446067 |
| Erah PO et al. | The stability of amoxycillin, clarithromycin and metronidazole in gastric juice: relevance to the treatment of Helicobacter pylori infection. | 1997 | J. Antimicrob. Chemother. | pmid:9044021 |
| Genné D et al. | Clarithromycin versus amoxicillin-clavulanic acid in the treatment of community-acquired pneumonia. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9447898 |
| Tonai A et al. | [Clarithromycin suppression of DNA synthesis by rat nasal mucosal cells enhanced by endotoxin instillation]. | 1997 | Jpn J Antibiot | pmid:9678983 |
| Roche B et al. | Efficacy of combined clarithromycin and sparfloxacin therapy in a patient with discitis: due to Mycobacterium xenopi. | 1997 | Rev Rhum Engl Ed | pmid:9051864 |
| Ridgway GL et al. | The in-vitro activity of grepafloxacin against Chlamydia spp., Mycoplasma spp., Ureaplasma urealyticum and Legionella spp. | 1997 | J. Antimicrob. Chemother. | pmid:9484871 |
| Martin SJ et al. | In vitro activity of clarithromycin alone and in combination with ciprofloxacin or levofloxacin against Legionella spp.: enhanced effect by the addition of the metabolite 14-hydroxy clarithromycin. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9401809 |
| Sander P et al. | The role of ribosomal RNAs in macrolide resistance. | 1997 | Mol. Microbiol. | pmid:9402018 |
| Yamamoto M et al. | [The clinical study of clarithromycin for pulmonary Mycobacterium avium-intracellulare complex infection]. | 1997 | Kekkaku | pmid:9038009 |
| Hoppe JE and Tschirner T | Comparison of Etest and agar dilution for testing the activity of three macrolides against Bordetella parapertussis. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9218920 |
| Dohil R et al. | Effective 2-wk therapy for Helicobacter pylori disease in children. | 1997 | Am. J. Gastroenterol. | pmid:9040199 |
| Lerang F et al. | Highly effective twice-daily triple therapies for Helicobacter pylori infection and peptic ulcer disease: does in vitro metronidazole resistance have any clinical relevance? | 1997 | Am. J. Gastroenterol. | pmid:9040200 |
| Visalli MA et al. | Susceptibility of twenty penicillin-susceptible and -resistant pneumococci to levofloxacin, ciprofloxacin, ofloxacin, erythromycin, azithromycin, and clarithromycin by MIC and time-kill. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9294703 |
| Brown BA et al. | Clarithromycin-associated digoxin toxicity in the elderly. | 1997 | Clin. Infect. Dis. | pmid:8994761 |
| Greco S et al. | Glossitis, stomatitis, and black tongue with lansoprazole plus clarithromycin and other antibiotics. | 1997 | Ann Pharmacother | pmid:9416400 |
| Zuberi BF et al. | Low dose, short-term, triple therapy for helicobacter pylori associated peptic ulcer. | 1997 | J Pak Med Assoc | pmid:9361485 |
| Zullo A et al. | Omeprazole plus clarithromycin and either tinidazole or tetracycline for Helicobacter pylori infection: a randomized prospective study. | 1997 | Am. J. Gastroenterol. | pmid:9362185 |
| Sugihara J et al. | [Efficacy of clarithromycin on chronic paranasal sinusitis--a comparison between children and adult]. | 1997 | Jpn J Antibiot | pmid:9597431 |
| Hamada K et al. | [Evaluation of antineoplastic effect of CAM (clarithromycin) in a mouse model inoculated with lung cancer cells]. | 1997 | Jpn J Antibiot | pmid:9597434 |
| Buckley MJ et al. | Metronidazole resistance reduces efficacy of triple therapy and leads to secondary clarithromycin resistance. | 1997 | Dig. Dis. Sci. | pmid:9365144 |
| Misiewicz JJ et al. | One week triple therapy for Helicobacter pylori: a multicentre comparative study. Lansoprazole Helicobacter Study Group. | 1997 | Gut | pmid:9462204 |
| Kokubo Y et al. | [Effects of clarithromycin on experimental pulmonary metastasis]. | 1997 | Jpn J Antibiot | pmid:9597436 |
| Loo VG et al. | In-vitro susceptibility of Helicobacter pylori to ampicillin, clarithromycin, metronidazole and omeprazole. | 1997 | J. Antimicrob. Chemother. | pmid:9462442 |
| Sakamoto M et al. | [Efficacy of clarithromycin on cancer cachexia in patients with primary non-small cell lung cancer]. | 1997 | Jpn J Antibiot | pmid:9597437 |
| Hoffner SE et al. | In-vitro activity of fluorinated quinolones and macrolides against drug-resistant Mycobacterium tuberculosis. | 1997 | J. Antimicrob. Chemother. | pmid:9462443 |
| Teramoto S et al. | [Fluctuation in the cytokine m-RNA content in primary non-small cell lung cancer caused by clarithromycin (CAM) administration]. | 1997 | Jpn J Antibiot | pmid:9597438 |
| Torresani C et al. | Clarithromycin versus doxycycline in the treatment of rosacea. | 1997 | Int. J. Dermatol. | pmid:9466207 |
| Mikasa K et al. | [Effect of clarithromycin on prolonging the life expectancy of patients with primary lung cancer]. | 1997 | Jpn J Antibiot | pmid:9597439 |
| Tzivras M et al. | One-week therapy with omeprazole, clarithromycin and metronidazole or ornidazole, followed by 3 weeks' treatment with omeprazole, eradicates Helicobacter pylori equally and heals duodenal ulcer. | 1997 | Eur J Gastroenterol Hepatol | pmid:9471024 |
| Kawasaki M et al. | Ménétrièr's disease associated with Helicobacter pylori infection: resolution of enlarged gastric folds and hypoproteinemia after antibacterial treatment. | 1997 | Am. J. Gastroenterol. | pmid:9382064 |
| Takeda H et al. | [Macrolide antibiotic actions on bacteria and cultured airway cells]. | 1997 | Jpn J Antibiot | pmid:9597448 |
| Adamek RJ et al. | Pantoprazole versus omeprazole in one-week low-dose triple therapy for curve of H. pylori infection. | 1997 | Am. J. Gastroenterol. | pmid:9382084 |
| McLaren A et al. | The role of ranitidine bismuth citrate in significantly reducing the emergence of Helicobacter pylori strains resistant to antibiotics. | 1997 | Helicobacter | pmid:9432317 |
| Nilius AM et al. | Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. | 1997 | J. Clin. Microbiol. | pmid:9163435 |
| Bardhan KD et al. | Effects of smoking on cure of Helicobacter pylori infection and duodenal ulcer recurrence in patients treated with clarithromycin and omeprazole. | 1997 | Helicobacter | pmid:9432318 |
| Moayyedi P | Amoxycillin dual therapy against Helicobacter pylori--the final nail in the coffin? | 1997 | Ital J Gastroenterol Hepatol | pmid:9513823 |
| Boixeda de Miquel D | [Efficacy of the triple therapy in the eradication of H. pylori in peptic ulcer]. | 1997 | Rev Esp Enferm Dig | pmid:9494374 |
| Bordet AL et al. | [Mycobacterium chelonae cutaneous infection: efficacy of prolonged treatment by clarithromycin]. | 1997 | Ann Dermatol Venereol | pmid:9686059 |
| Thornsberry C et al. | Surveillance of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States in 1996-1997 respiratory season. The Laboratory Investigator Group. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9458982 |
| Briant C et al. | Pericarditis as a manifestation of Lyme disease. | 1997 | J Emerg Nurs | pmid:9460386 |
| Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
| McCracken GH | Microbiologic activity of the newer macrolide antibiotics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109155 |
| Tarlow MJ | Macrolides in the management of streptococcal pharyngitis/tonsillitis. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109157 |
| Lévy M et al. | Endoscopic ultrasonography for the initial staging and follow-up in patients with low-grade gastric lymphoma of mucosa-associated lymphoid tissue treated medically. | 1997 | Gastrointest. Endosc. | pmid:9351036 |
| Laine L et al. | A United States multicentre trial of dual and proton pump inhibitor-based triple therapies for Helicobacter pylori. | 1997 | Aliment. Pharmacol. Ther. | pmid:9354200 |
| Rinaldi V et al. | The management of failed dual or triple therapy for Helicobacter pylori eradication. | 1997 | Aliment. Pharmacol. Ther. | pmid:9354202 |
| Breuer T et al. | Clarithromycin, amoxycillin and H2-receptor antagonist therapy for Helicobacter pylori peptic ulcer disease in Korea. | 1997 | Aliment. Pharmacol. Ther. | pmid:9354204 |
| Wurzer H et al. | Short-course therapy with amoxycillin-clarithromycin triple therapy for 10 days (ACT-10) eradicates Helicobacter pylori and heals duodenal ulcer. ACT-10 Study Group. | 1997 | Aliment. Pharmacol. Ther. | pmid:9354205 |
| Harris A | H. pylori eradication by LAC. | 1997 | Aliment. Pharmacol. Ther. | pmid:9354216 |
| Jablonowski H et al. | Ancillary benefits of Mycobacterium avium-intracellulare complex prophylaxis with clarithromycin in HIV-infected patients. | 1997 | Drugs | pmid:9358196 |
| Grosset J and Ji B | Prevention of the selection of clarithromycin-resistant Mycobacterium avium-intracellulare complex. | 1997 | Drugs | pmid:9358197 |
| Dubé MP et al. | A randomized evaluation of ethambutol for prevention of relapse and drug resistance during treatment of Mycobacterium avium complex bacteremia with clarithromycin-based combination therapy. California Collaborative Treatment Group. | 1997 | J. Infect. Dis. | pmid:9359722 |
| Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group. | 1997 | Gut | pmid:9274464 | |
| Lam SK et al. | Does treatment of Helicobacter pylori with antibiotics alone heal duodenal ulcer? A randomised double blind placebo controlled study. | 1997 | Gut | pmid:9274470 |
| Kato A | [Effect of erythromycin and clarithromycin on ion transport across dissected canine tracheal epithelium]. | 1997 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9103848 |
| Hirakawa T | [Diagnosis and treatment of Helicobacter pylori]. | 1997 | Nippon Ika Daigaku Zasshi | pmid:9283206 |
| Meyer JM et al. | In vitro synergy testing of clarithromycin and 14-hydroxyclarithromycin with amoxicillin or bismuth subsalicylate against Helicobacter pylori. | 1997 | Antimicrob. Agents Chemother. | pmid:9210696 |
| Chimura T | [Measurement of antibody titers to chlamydial infection and effects of levofloxacin in cystic cervicitis and chlamydial infection]. | 1997 | Jpn J Antibiot | pmid:9212369 |
| Lim AG et al. | Helicobacter pylori eradication using a 7-day regimen of low-dose clarithromycin, lansoprazole and amoxycillin. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218079 |
| Laine L et al. | Randomized comparison of ranitidine bismuth citrate-based triple therapies for Helicobacter pylori. | 1997 | Am. J. Gastroenterol. | pmid:9399755 |
| Srinivasan R and Minocha A | Cure of Helicobacter pylori: a hidden curse? | 1997 | Am. J. Gastroenterol. | pmid:9399784 |
| Different clarithromycin doses affect mortality. | 1997 | AIDS Patient Care STDS | pmid:11361754 | |
| Sekkarie MA | Torsades de pointes in two chronic renal failure patients treated with cisapride and clarithromycin. | 1997 | Am. J. Kidney Dis. | pmid:9292575 |
| Akaki T et al. | [In vivo activities of benzoxazinorifamycin KRM-1648, clarithromycin, and levofloxacin, or combination of KRM-1648 with diclofenac sodium against Mycobacterium avium infection induced in mice]. | 1997 | Kekkaku | pmid:9293712 |
| Recker MW and Kier KL | Potential interaction between clarithromycin and warfarin. | 1997 | Ann Pharmacother | pmid:9296238 |
| Laberge P and Martineau P | Clarithromycin-induced digoxin intoxication. | 1997 | Ann Pharmacother | pmid:9296239 |
| Matsukura N | [Two step therapy for education of Helicobacter pylori]. | 1997 | Nihon Shokakibyo Gakkai Zasshi | pmid:9284449 |
| Bardhan KD et al. | Ranitidine bismuth citrate with clarithromycin for the treatment of duodenal ulcer. | 1997 | Gut | pmid:9301496 |
| Tan WC et al. | Helicobacter pylori eradication--comparison of three drug regimens and symptomatic assessment in duodenitis and antral gastritis. | 1997 | Int. J. Clin. Pract. | pmid:9287260 |
| Kobler E et al. | [Effectiveness of short-term triple therapy for healing Helicobacter pylori infection in ulcer disease]. | 1997 | Schweiz Med Wochenschr Suppl | pmid:9289833 |