clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Starostin BD | [Modern means of anti-Helicobacter therapy]. | 2001 | Voen Med Zh | pmid:11764485 |
Vichev E et al. | [Gastroduodenitis and ulcers--statistical study for 1998]. | 2000 | Vutr Boles | pmid:11688321 |
Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
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Abegglen C et al. | The fate of selected micropollutants in a single-house MBR. | 2009 | Water Res. | pmid:19269669 |
Vione D et al. | Phototransformation of selected human-used macrolides in surface water: kinetics, model predictions and degradation pathways. | 2009 | Water Res. | pmid:19249811 |
Wang S et al. | Enhanced adsorption of ionizable antibiotics on activated carbon fiber under electrochemical assistance in continuous-flow modes. | 2018 | Water Res. | pmid:29426033 |
Siemens J et al. | Concentrations and mobility of human pharmaceuticals in the world's largest wastewater irrigation system, Mexico City-Mezquital Valley. | 2008 | Water Res. | pmid:18083208 |
Forrez I et al. | Biogenic metals for the oxidative and reductive removal of pharmaceuticals, biocides and iodinated contrast media in a polishing membrane bioreactor. | 2011 | Water Res. | pmid:21163512 |
Yamashita N et al. | Effects of antibacterial agents, levofloxacin and clarithromycin, on aquatic organisms. | 2006 | Water Sci. Technol. | pmid:16862775 |
Sahar E et al. | Comparison of two treatments for the removal of selected organic micropollutants and bulk organic matter: conventional activated sludge followed by ultrafiltration versus membrane bioreactor. | 2011 | Water Sci. Technol. | pmid:21330721 |
Lin AY et al. | Fate of selected pharmaceuticals and personal care products after secondary wastewater treatment processes in Taiwan. | 2010 | Water Sci. Technol. | pmid:21076233 |
Ghosh GC et al. | Occurrence and elimination of antibiotics at four sewage treatment plants in Japan and their effects on bacterial ammonia oxidation. | 2009 | Water Sci. Technol. | pmid:19237773 |
Harada A et al. | Biological effects of PPCPs on aquatic lives and evaluation of river waters affected by different wastewater treatment levels. | 2008 | Water Sci. Technol. | pmid:19001705 |
Nakada N et al. | Occurrence of 70 pharmaceutical and personal care products in Tone River basin in Japan. | 2007 | Water Sci. Technol. | pmid:18075189 |
Sein MM et al. | Oxidation of some typical wastewater contaminants (tributyltin, clarithromycin, metoprolol and diclofenac) by ozone. | 2009 | Water Sci. Technol. | pmid:19403960 |
Feng X et al. | [Interaction between biofilm formed by Pseudomonas aeruginosa and antibacterial agents]. | 2000 | Wei Sheng Wu Xue Bao | pmid:12548947 |
Dhawan VK et al. | Vancomycin-resistant enterococcal colonization in nonhospitalized HIV-infected patients. | 1998 | West. J. Med. | pmid:9830355 |
Kanatani MS and Guglielmo BJ | The new macrolides. Azithromycin and clarithromycin. | 1994 | West. J. Med. | pmid:8128699 |
Kardas P and Muras M | [A blinded comparison of palatability of 13 common pediatric antibiotic suspensions]. | 2005 | Wiad. Lek. | pmid:15991547 |