clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hyperemesis Gravidarum D006939 2 associated lipids
Empyema, Pleural D016724 2 associated lipids
Mastoiditis D008417 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Scrub Typhus D012612 3 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Typhoid Fever D014435 2 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Splenic Diseases D013158 5 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Leprosy, Lepromatous D015440 2 associated lipids
Gastritis, Hypertrophic D005758 1 associated lipids
Hypoproteinemia D007019 1 associated lipids
Cutaneous Fistula D017577 1 associated lipids
Tuberculosis, Ocular D014392 1 associated lipids
Euthyroid Sick Syndromes D005067 1 associated lipids
Parotid Diseases D010305 1 associated lipids
Achlorhydria D000126 1 associated lipids
Eye Infections D015817 1 associated lipids
Buruli Ulcer D054312 1 associated lipids
Leprosy, Paucibacillary D056005 2 associated lipids
Granuloma, Plasma Cell D006104 1 associated lipids
Encephalomyelitis, Acute Disseminated D004673 1 associated lipids
Immune Reconstitution Inflammatory Syndrome D054019 1 associated lipids
Parotid Neoplasms D010307 2 associated lipids
Extensively Drug-Resistant Tuberculosis D054908 1 associated lipids
Upper Extremity Deep Vein Thrombosis D056824 1 associated lipids
Immunoproliferative Small Intestinal Disease D007161 2 associated lipids
Tuberculosis, Spinal D014399 1 associated lipids
Epilepsy, Partial, Motor D020938 1 associated lipids
Empyema, Tuberculous D004654 1 associated lipids
Serositis D012700 1 associated lipids
Glossitis, Benign Migratory D005929 1 associated lipids
Sacroiliitis D058566 1 associated lipids
Pseudomyxoma Peritonei D011553 1 associated lipids
Tooth, Nonvital D019553 2 associated lipids
Myxoma D009232 1 associated lipids
Kleine-Levin Syndrome D017593 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Cadranel S et al. Improvement of the eradication rate of Helicobacter pylori gastritis in children is by adjunction of omeprazole to a dual antibiotherapy. 2007 Acta Paediatr. pmid:17187610
Main KM et al. Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient. 2002 Acta Paediatr. pmid:12412882
Hurduc V et al. A randomized, open trial evaluating the effect of Saccharomyces boulardii on the eradication rate of Helicobacter pylori infection in children. 2009 Acta Paediatr. pmid:18681892
Forslöw U et al. Early chemotherapy for non-tuberculous mycobacterial infections in patients with cystic fibrosis. 2003 Acta Paediatr. pmid:12948065
Tirén U et al. Helicobacter pylori gastritis in children: efficacy of 2 weeks of treatment with clarithromycin, amoxicillin and omeprazole. 1999 Acta Paediatr. pmid:10102149
König C et al. Legionella waltersii--a novel cause of pneumonia? 2005 Acta Paediatr. pmid:16299887
Luo X et al. Evaluation of CYP3A activity in humans using three different parameters based on endogenous cortisol metabolism. 2009 Acta Pharmacol. Sin. pmid:19701237
Cao S et al. Pharmacokinetic interactions between ilaprazole and clarithromycin following ilaprazole, clarithromycin and amoxicillin triple therapy. 2012 Acta Pharmacol. Sin. pmid:22820908
Qiao AM et al. Involvement of mitochondria and caspase pathways in N-demethyl-clarithromycin-induced apoptosis in human cervical cancer HeLa cell. 2006 Acta Pharmacol. Sin. pmid:17112418
Zhang L et al. P-glycoprotein restricted transport of nimodipine across blood-brain barrier. 2003 Acta Pharmacol. Sin. pmid:12956939
UÄŸurlu T et al. Optimization and evaluation of clarithromycin floating tablets using experimental mixture design. 2014 Mar-Apr Acta Pol Pharm pmid:25272652
Ozkan Y et al. Clarithromycin targeting to lung: optimization of the size, morphology and release characteristics of albumin microspheres. 2000 Sep-Oct Acta Pol Pharm pmid:11126029
Patel SS et al. Formualtion and evaluation of floating drug delivery system containing clarithromycin for Helicobacter pylori. 2006 Jan-Feb Acta Pol Pharm pmid:17515330
Baranowski WJ Clarithromycin-induced hypomania in a child - a case report. 2010 Acta Psychiatr Scand pmid:20491717
Cameselle D et al. [Sporotrichoid cutaneous infection by Mycobacterium haemophilum in an AIDS patient]. 2007 Actas Dermosifiliogr pmid:17504704
Gutiérrez-de la Peña J et al. [Three cases of panniculitis due to Mycobacterium abscessus after mesotherapy]. 2010 Actas Dermosifiliogr pmid:20223169
Iwańczak BM et al. Assessment of Sequential and Standard Triple Therapy in Treatment of Helicobacter pylori Infection in Children Dependent on Bacteria Sensitivity to Antibiotics. Adv Clin Exp Med pmid:27629844
Gościniak G et al. Frequency of infection with Helicobacter pylori isolates of different antimicrobial profiles in children and adolescents: A preliminary study. Adv Clin Exp Med pmid:28791844
Radzikowska E et al. Clarithromycin Decreases IL-6 Concentration in Serum and BAL Fluid in Patients with Cryptogenic Organizing Pneumonia. Adv Clin Exp Med pmid:28028949
Tuchman SA et al. Lenalidomide before and after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma. 2012 Adv Hematol pmid:22690220