clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Bradycardia D001919 13 associated lipids
Endometriosis D004715 29 associated lipids
Myocardial Infarction D009203 21 associated lipids
Proteinuria D011507 30 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Arteriosclerosis D001161 86 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Fractures, Open D005597 3 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Drugs for treatment of peptic ulcers. 1997 Med Lett Drugs Ther pmid:8996458
Taylor JL et al. Pharmacoeconomic comparison of treatments for the eradication of Helicobacter pylori. 1997 Arch. Intern. Med. pmid:8996045
Torresin A et al. Vinca alkaloids and macrolides in human immunodeficiency virus-related malignancies: a safe association. 1996 Cancer Chemother. Pharmacol. pmid:8995518
Raasveld MH et al. Cat-scratch disease mimicking pancreatic malignancy: case report. 1997 Clin. Infect. Dis. pmid:8994767
de'Clari F Ciprofloxacin was the culprit--not itraconazole. 1997 Clin. Infect. Dis. pmid:8994764
Brown BA et al. Clarithromycin-associated digoxin toxicity in the elderly. 1997 Clin. Infect. Dis. pmid:8994761
Hachem CY et al. Antimicrobial susceptibility testing of Helicobacter pylori. Comparison of E-test, broth microdilution, and disk diffusion for ampicillin, clarithromycin, and metronidazole. 1996 Diagn. Microbiol. Infect. Dis. pmid:8988762
Fischbach W et al. Regression of immunoproliferative small intestinal disease after eradication of Helicobacter pylori. 1997 Lancet pmid:8988128
Ono T et al. In vitro and in vivo antibacterial activities of clarithromycin. 1996 May-Jun Chemotherapy pmid:8983882
MacFarlane JT et al. Comparison of amoxycillin and clarithromycin as initial treatment of community-acquired lower respiratory tract infections. 1996 Br J Gen Pract pmid:8983255
Brenciaglia MI et al. Inhibitory and bactericidal activity of rokitamycin against Helicobacter pylori and morphological alterations. 1996 J Chemother pmid:8981182
Adachi T et al. Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. 1996 J. Allergy Clin. Immunol. pmid:8977529
Pozniak A and Nelson MR Against the proposition: all patients with advanced HIV disease should be offered rifabutin prophylaxis. 1996 Genitourin Med pmid:8976832
Iwata M et al. [Bronchiolitis obliterans preceding rheumatoid arthritis: effect of clarithromycin]. 1996 Nihon Kyobu Shikkan Gakkai Zasshi pmid:8976086
Naoki K et al. [Two cases of pulmonary disease caused by Mycobacterium chelonae subsp. abscessus]. 1996 Nihon Kyobu Shikkan Gakkai Zasshi pmid:8976085
Laine L et al. Randomized comparison of differing periods of twice-a-day triple therapy for the eradication of Helicobacter pylori. 1996 Aliment. Pharmacol. Ther. pmid:8971306
Pilotto A et al. Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. 1996 Aliment. Pharmacol. Ther. pmid:8971305
Moshkowitz M et al. One week triple therapy with omeprazole, clarithromycin and tinidazole for Helicobacter pylori: differing efficacy in previously treated and untreated patients. 1996 Aliment. Pharmacol. Ther. pmid:8971304
Harris AW et al. Lansoprazole, clarithromycin and metronidazole for seven days in Helicobacter pylori infection. 1996 Aliment. Pharmacol. Ther. pmid:8971302
Cammarota G et al. Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. 1996 Aliment. Pharmacol. Ther. pmid:8971300
Peeling RW and Brunham RC Chlamydiae as pathogens: new species and new issues. 1996 Oct-Dec Emerging Infect. Dis. pmid:8969247
Grau E et al. Interaction between clarithromycin and oral anticoagulants. 1996 Ann Pharmacother pmid:8968465
Labenz J [Current developments in Helicobacter pylori therapy]. 1996 Leber Magen Darm pmid:8965606
Diemer PR et al. [Rifabutin-induced hypopyon iritis in HIV infection]. 1996 Klin Monbl Augenheilkd pmid:8965476
Murakami K et al. Atopic dermatitis successfully treated by eradication of Helicobacter pylori. 1996 J. Gastroenterol. pmid:8959527
Tonokatsu Y et al. Eradication of Helicobacter pylori followed by reinfection. 1996 J. Gastroenterol. pmid:8959526
Shimoyama T et al. Ecabet sodium eradicates Helicobacter pylori infection in gastric ulcer patients. 1996 J. Gastroenterol. pmid:8959522
Satoh K et al. Efficacy of clarithromycin in eradicating Helicobacter pylori. 1996 J. Gastroenterol. pmid:8959520
Moreno JA et al. Significant increase in eradication rates of Helicobacter pylori infection with two consecutive dual therapies (omeprazole and amoxycillin or omeprazole and clarithromycin). A randomized study in 450 Spanish patients. 1996 J. Gastroenterol. pmid:8959519
Griffith DE et al. Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. 1996 Clin. Infect. Dis. pmid:8953085
Nagashima R et al. Regression of duodenal mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori. 1996 Gastroenterology pmid:8942749
Bermudez LE et al. Effect of ethambutol on emergence of clarithromycin-resistant Mycobacterium avium complex in the beige mouse model. 1996 J. Infect. Dis. pmid:8940212
Flamm RK et al. Kill kinetics of antimicrobial agents against Helicobacter pylori. 1996 J. Antimicrob. Chemother. pmid:8937967
Koguchi M et al. [Antimicrobial activities of clarithromycin against clinical isolates]. 1996 Jpn J Antibiot pmid:8935125
Yago K et al. [Protein binding of clarithromycin in patients with chronic renal failure]. 1996 Jpn J Antibiot pmid:8935121
Vilmànyi E et al. Clarithromycin pharmacokinetics after oral administration with or without fasting in crossbred beagles. 1996 J Small Anim Pract pmid:8934426
Alder JD et al. Relevance of the ferret model of Helicobacter-induced gastritis to evaluation of antibacterial therapies. 1996 Am. J. Gastroenterol. pmid:8931416
van der Hulst RW et al. Therapeutic options after failed Helicobacter pylori eradication therapy. 1996 Am. J. Gastroenterol. pmid:8931413
Muñoz N et al. Chemoprevention trial on precancerous lesions of the stomach in Venezuela: summary of study design and baseline data. 1996 IARC Sci. Publ. pmid:8923024
Aoyama T et al. Efficacy of short-term treatment of pertussis with clarithromycin and azithromycin. 1996 J. Pediatr. pmid:8917247
Kuo CC et al. In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae. 1996 Antimicrob. Agents Chemother. pmid:8913488
Koeck JL et al. Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment. 1996 Clin. Infect. Dis. pmid:8909856
Kondoh K et al. Inhibitory activity of clarithromycin on biofilm synthesis with Pseudomonas aeruginosa. 1996 Acta Otolaryngol Suppl pmid:8908271
Pavlopoulou J et al. Randomized controlled study of clarithromycin versus cefaclor suspensions in the treatment of acute otitis media in children. 1995 J Chemother pmid:8904139
Segreti J et al. In vitro activity of macrolides against intracellular Legionella pneumophila. 1996 Diagn. Microbiol. Infect. Dis. pmid:8902407
Flurer CL Analysis of macrolide antibiotics by capillary electrophoresis. 1996 Electrophoresis pmid:8900943
Schütze K et al. Clarithromycin or amoxycillin plus high-dose ranitidine in the treatment of Helicobacter pylori-positive functional dyspepsia. 1996 Eur J Gastroenterol Hepatol pmid:8900907
Three new studies expand understanding of MAC therapy. 1996 Am J Health Syst Pharm pmid:8899122
Spadaccini A et al. Omeprazole versus ranitidine: short-term triple-therapy in patients with Helicobacter pylori-positive duodenal ulcers. 1996 Aliment. Pharmacol. Ther. pmid:8899094
Ghebremichael S et al. Antimycobacterial synergism of clarithromycin and rifabutin. 1996 Scand. J. Infect. Dis. pmid:8893404