| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphoma, T-Cell, Cutaneous | D016410 | 4 associated lipids |
| Eye Infections, Bacterial | D015818 | 3 associated lipids |
| Eye Infections | D015817 | 1 associated lipids |
| Eye Injuries, Penetrating | D015807 | 2 associated lipids |
| Leprosy, Lepromatous | D015440 | 2 associated lipids |
| Leprosy, Borderline | D015439 | 3 associated lipids |
| Discitis | D015299 | 2 associated lipids |
| Mycobacterium avium-intracellulare Infection | D015270 | 4 associated lipids |
| Sexually Transmitted Diseases, Bacterial | D015231 | 5 associated lipids |
| Wound Infection | D014946 | 12 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Morikawa K et al. | Modulatory effect of antibiotics on cytokine production by human monocytes in vitro. | 1996 | Antimicrob. Agents Chemother. | pmid:8726002 |
| Arain TM et al. | Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery. | 1996 | Antimicrob. Agents Chemother. | pmid:8726034 |
| Shafran SD et al. | A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group. | 1996 | N. Engl. J. Med. | pmid:8676931 |
| Shimoyama T et al. | Validity of various diagnostic tests to evaluate cure of Helicobacter pylori infection. | 1996 | J. Gastroenterol. | pmid:8680535 |
| Berg-Candolfi M and Candolfi E | Depression of the N-demethylation of erythromycin, azithromycin, clarithromycin and clindamycin in murine Toxoplasma infection. | 1996 | Int. J. Parasitol. | pmid:9024879 |
| Griffith DE et al. | Varying dosages of rifabutin affect white blood cell and platelet counts in human immunodeficiency virus--negative patients who are receiving multidrug regimens for pulmonary Mycobacterium avium complex disease. | 1996 | Clin. Infect. Dis. | pmid:8953085 |
| Pellegrin I et al. | Activity of rifabutin, clarithromycin, ethambutol, sparfloxacin and amikacin, alone and in combination, against Mycobacterium avium complex in human macrophages. | 1996 | J. Antimicrob. Chemother. | pmid:9182107 |
| Hultén K et al. | New pharmacokinetic in vitro model for studies of antibiotic activity against intracellular microorganisms. | 1996 | Antimicrob. Agents Chemother. | pmid:9124830 |
| Matsuoka N et al. | Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells. | 1996 | Clin. Exp. Immunol. | pmid:9099936 |
| Young LS | Treatment and prophylaxis of Mycobacterium avium complex. | 1996 | Int J STD AIDS | pmid:8652724 |
| Kuo CC et al. | In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8913488 |
| Aoyama T et al. | Efficacy of short-term treatment of pertussis with clarithromycin and azithromycin. | 1996 | J. Pediatr. | pmid:8917247 |
| Alarcón T et al. | In vitro activity of omeprazole in combination with several antimicrobial agents against clinical isolates of Helicobacter pylori. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9031877 |
| Burucoa C et al. | Western blot monitoring of disseminated Nocardia nova infection treated with clarithromycin, imipenem, and surgical drainage. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9031879 |
| Ramirez Mayans JA et al. | [Elimination of Helicobacter pylori in patients with recurrent abdominal pain with simultaneous administration of ranitidine, bismuth subsalicylate and clarithromycin]. | 1996 | Acta Gastroenterol. Latinoam. | pmid:9363265 |
| Cammarota G et al. | Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971300 |
| Pilotto A et al. | Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971305 |
| Adachi T et al. | Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. | 1996 | J. Allergy Clin. Immunol. | pmid:8977529 |
| Dammann HG | Therapy with omeprazole and clarithromycin increases serum carbamazepine levels in patients with H. pylori gastritis. | 1996 | Dig. Dis. Sci. | pmid:8617126 |
| Meyboom RH et al. | [Possible potentiation of phenprocoumon by clarithromycin and roxithromycin]. | 1996 | Ned Tijdschr Geneeskd | pmid:8628425 |
| Hunt RH | Eradication of Helicobacter pylori infection. | 1996 | Am. J. Med. | pmid:8644782 |
| Tonokatsu Y et al. | Eradication of Helicobacter pylori followed by reinfection. | 1996 | J. Gastroenterol. | pmid:8959526 |
| Murakami K et al. | Atopic dermatitis successfully treated by eradication of Helicobacter pylori. | 1996 | J. Gastroenterol. | pmid:8959527 |
| Diemer PR et al. | [Rifabutin-induced hypopyon iritis in HIV infection]. | 1996 | Klin Monbl Augenheilkd | pmid:8965476 |
| Labenz J | [Current developments in Helicobacter pylori therapy]. | 1996 | Leber Magen Darm | pmid:8965606 |
| Grau E et al. | Interaction between clarithromycin and oral anticoagulants. | 1996 | Ann Pharmacother | pmid:8968465 |
| Muñoz N et al. | Chemoprevention trial on precancerous lesions of the stomach in Venezuela: summary of study design and baseline data. | 1996 | IARC Sci. Publ. | pmid:8923024 |
| Dhaenens L et al. | In-vitro activities of clarithromycin and other antimicrobial agents against Helicobacter pylori isolated from children. | 1996 | J. Antimicrob. Chemother. | pmid:8877551 |
| Tursi A et al. | Helicobacter pylori eradication helps resolve pyloric and duodenal stenosis. | 1996 | J. Clin. Gastroenterol. | pmid:8877648 |
| Chen S et al. | [Omeprazole, clarithromycin and amoxicillin therapy for Helicobacter pylori infection]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9592303 |
| Liu W et al. | [Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection]. | 1996 | Zhonghua Nei Ke Za Zhi | pmid:9592304 |
| Xu G et al. | [Effect of clarithromycin on cytocidal activity against Pseudomonas aeruginosa in mice peritoneal cavity]. | 1996 | Kansenshogaku Zasshi | pmid:8822058 |
| Pijpers E et al. | A clarithromycin-induced myasthenic syndrome. | 1996 | Clin. Infect. Dis. | pmid:8824993 |
| Webb DD | Practice guidelines for treatment of peptic ulcer disease. | 1996 | JAMA | pmid:8827959 |
| Erah PO et al. | Ion-pair high-performance liquid chromatographic assay method for the assessment of clarithromycin stability in aqueous solution and in gastric juice. | 1996 | J. Chromatogr. B, Biomed. Appl. | pmid:8832427 |
| Vangala R and Cernek PK | Hypersensitivity reaction to clarithromycin. | 1996 | Ann Pharmacother | pmid:8833572 |
| Ji B et al. | Bactericidal activities of combinations of new drugs against Mycobacterium leprae in nude mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834886 |
| Yamamoto T et al. | Activity of KRM-1648 alone or in combination with both ethambutol and kanamycin or clarithromycin against Mycobacterium intracellulare infections in beige mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834892 |
| Ji B et al. | How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice? | 1996 | Antimicrob. Agents Chemother. | pmid:8834894 |
| Riff DS et al. | Triple therapy with lansoprazole, clarithromycin, and amoxicillin for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398874 |
| Harford W et al. | Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection. | 1996 | Helicobacter | pmid:9398875 |
| Schwartz H et al. | Seven-day triple therapy with lansoprazole, clarithromycin, and metronidazole for the cure of Helicobacter pylori infection: a short report. | 1996 | Helicobacter | pmid:9398876 |
| Jaup BK | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin, and clarithromycin. | 1996 | Helicobacter | pmid:9398878 |
| Moayyedi P et al. | Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori. | 1996 | Helicobacter | pmid:9398880 |
| Brenciaglia MI et al. | Inhibitory and bactericidal activity of rokitamycin against Helicobacter pylori and morphological alterations. | 1996 | J Chemother | pmid:8981182 |
| Unge P | Review of Helicobacter pylori eradication regimens. | 1996 | Scand. J. Gastroenterol. Suppl. | pmid:8722388 |
| Bazzoli F | Italian omeprazole triple therapy--a 1-week regimen. | 1996 | Scand. J. Gastroenterol. Suppl. | pmid:8722395 |
| Goddard AF and Logan RP | Antimicrobial resistance and Helicobacter pylori. | 1996 | J. Antimicrob. Chemother. | pmid:8722530 |
| Barry AL et al. | Reassessment of methods for testing the susceptibility of Haemophilus influenzae to clarithromycin. | 1996 | J. Antimicrob. Chemother. | pmid:8722555 |
| H. pylori treatment recognized by FDA. | 1996 | Am J Health Syst Pharm | pmid:8725200 |