| MeSH term | MeSH ID | Detail |
|---|---|---|
| Prosthesis-Related Infections | D016459 | 7 associated lipids |
| Fibrosis | D005355 | 23 associated lipids |
| Tooth Discoloration | D014075 | 7 associated lipids |
| Sinusitis | D012852 | 9 associated lipids |
| Fusobacterium Infections | D005674 | 3 associated lipids |
| Enterocolitis, Pseudomembranous | D004761 | 8 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Urinary Tract Infections | D014552 | 11 associated lipids |
| Cross Infection | D003428 | 9 associated lipids |
| Pseudomonas Infections | D011552 | 25 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yazdanbakhsh AR et al. | Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. | 2016 | Water Environ. Res. | pmid:28661328 |
| Sancak S et al. | Intestinal blood flow by Doppler ultrasound: the impact of clarithromycin treatment for feeding intolerance in preterm neonates. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26135789 |
| Uehara H et al. | Comparison of the Anti-angiogenic and Anti-inflammatory Effects of Two Antibiotics: Clarithromycin Versus Moxifloxacin. | 2016 | Curr. Eye Res. | pmid:26125497 |
| Ohe M et al. | A case of lupus nephritis treated with clarithromycin, tacrolimus, and glucocorticoids. | 2016 | Kaohsiung J. Med. Sci. | pmid:27638410 |
| Campillo A et al. | [Cuadruple concomitant non-bismuth therapy vs. classical triple therapy as first line therapy for Helicobacter pylori infection]. | 2016 | Med Clin (Barc) | pmid:27374029 |
| Khashei R et al. | High rate of A2142G point mutation associated with clarithromycin resistance among Iranian Helicobacter pylori clinical isolates. | 2016 | APMIS | pmid:27357065 |
| Alarcón-Millán J et al. | Clarithromycin resistance and prevalence of Helicobacter pylori virulent genotypes in patients from Southern México with chronic gastritis. | 2016 | Infect. Genet. Evol. | pmid:27355861 |
| Oberhofer E | [Quadruple therapy is more effective against H. pylori]. | 2016 | MMW Fortschr Med | pmid:27155683 |
| Mayor S | Short term increase in neuropsychiatric events is seen with H pylori treatment containing clarithromycin. | 2016 | BMJ | pmid:27143325 |
| Shokri-Shirvani J et al. | Letter: global emergence of Helicobacter pylori antibiotic resistance - unanswered questions. | 2016 | Aliment. Pharmacol. Ther. | pmid:27137738 |
| Wong IC | Author's reply to Blake. | 2016 | BMJ | pmid:26957514 |
| Todo K et al. | Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female. | 2016 | Ann. Hematol. | pmid:26957356 |
| Iyer G and Alexander GC | Editorialists' reply to Blake. | 2016 | BMJ | pmid:26957321 |
| Miglietta F et al. | A rare case of Saprochaete capitata fungemia in a critical ill patient without hematologic and oncological disorders. | 2016 | Rev Esp Quimioter | pmid:26785226 |
| Raymond J et al. | Diagnosis of Helicobacter pylori recurrence: relapse or reinfection? Usefulness of molecular tools. | 2016 | Scand. J. Gastroenterol. | pmid:26784882 |
| Eszik I et al. | High dynamic range detection of Chlamydia trachomatis growth by direct quantitative PCR of the infected cells. | 2016 | J. Microbiol. Methods | pmid:26578244 |
| Jain SK et al. | Lectin-Conjugated Clarithromycin and Acetohydroxamic Acid-Loaded PLGA Nanoparticles: a Novel Approach for Effective Treatment of H. pylori. | 2016 | AAPS PharmSciTech | pmid:26566630 |
| Di Giulio M et al. | In vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in Central Italy. | 2016 | Scand. J. Gastroenterol. | pmid:26554617 |
| Chen CH et al. | Mycobacterium abscessus complex bacteremia due to prostatitis after prostate biopsy. | 2016 | Indian J Tuberc | pmid:27998503 |
| Gehlot V et al. | Low prevalence of clarithromycin-resistant Helicobacter pylori isolates with A2143G point mutation in the 23S rRNA gene in North India. | 2016 | J Glob Antimicrob Resist | pmid:27530837 |
| Xuan SH et al. | Detection of clarithromycin-resistant Helicobacter pylori in clinical specimens by molecular methods: A review. | 2016 | J Glob Antimicrob Resist | pmid:27436390 |
| Lee J et al. | A new antibiotic regimen treats and prevents intra-amniotic inflammation/infection in patients with preterm PROM. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26441216 |
| Shimizu T and Suzaki H | Past, present and future of macrolide therapy for chronic rhinosinusitis in Japan. | 2016 | Auris Nasus Larynx | pmid:26441370 |
| Braden B | The best and worst treatments for Helicobacter pylori. | 2015 | BMJ | pmid:26290321 |
| Li BZ et al. | Comparative effectiveness and tolerance of treatments for Helicobacter pylori: systematic review and network meta-analysis. | 2015 | BMJ | pmid:26290044 |
| Zhang T | Physiologically based pharmacokinetic modeling of disposition and drug-drug interactions for atorvastatin and its metabolites. | 2015 | Eur J Pharm Sci | pmid:26116278 |
| Fraser LA et al. | Calcium channel blocker-clarithromycin drug interaction did not increase the risk of nonvertebral fracture: a population-based study. | 2015 | Ann Pharmacother | pmid:25429094 |
| Lee SJ et al. | Clarithromycin Attenuates Radiation-Induced Lung Injury in Mice. | 2015 | PLoS ONE | pmid:26114656 |
| Dimer F et al. | Inhalable Clarithromycin Microparticles for Treatment of Respiratory Infections. | 2015 | Pharm. Res. | pmid:26113237 |
| Mahmoudi A et al. | Microbiological assay for the analysis of certain macrolides in pharmaceutical dosage forms. | 2015 | Int J Pharm | pmid:26112961 |
| Nonaka L et al. | Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. | 2015 | Lett. Appl. Microbiol. | pmid:25765542 |
| Thellin O et al. | In vitro approach to study the synergistic effects of tobramycin and clarithromycin against Pseudomonas aeruginosa biofilms using prokaryotic or eukaryotic culture media. | 2015 | Int. J. Antimicrob. Agents | pmid:25963337 |
| Hwang JJ et al. | Efficacy of moxifloxacin-based sequential therapy for first-line eradication of Helicobacter pylori infection in gastrointestinal disease. | 2015 | World J. Gastroenterol. | pmid:25945019 |
| Liou JM et al. | The Primary Resistance of Helicobacter pylori in Taiwan after the National Policy to Restrict Antibiotic Consumption and Its Relation to Virulence Factors-A Nationwide Study. | 2015 | PLoS ONE | pmid:25942450 |
| Ferreri AJ et al. | High-dose clarithromycin is an active monotherapy for patients with relapsed/refractory extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT): the HD-K phase II trial. | 2015 | Ann. Oncol. | pmid:25935794 |
| Takahashi C et al. | Observation of antibacterial effect of biodegradable polymeric nanoparticles on Staphylococcus epidermidis biofilm using FE-SEM with an ionic liquid. | 2015 | Microscopy (Oxf) | pmid:25757698 |
| Metanat HA et al. | Comparison Between 10- and 14-Day Hybrid Regimens for Helicobacter pylori Eradication: A Randomized Clinical Trial. | 2015 | Helicobacter | pmid:25752357 |
| Spaniol V et al. | Moraxella catarrhalis AcrAB-OprM efflux pump contributes to antimicrobial resistance and is enhanced during cold shock response. | 2015 | Antimicrob. Agents Chemother. | pmid:25583725 |
| Chu HS et al. | Nontuberculous mycobacterial ocular infections--comparing the clinical and microbiological characteristics between Mycobacterium abscessus and Mycobacterium massiliense. | 2015 | PLoS ONE | pmid:25581038 |
| Lee HJ et al. | Concomitant therapy achieved the best eradication rate for Helicobacter pylori among various treatment strategies. | 2015 | World J. Gastroenterol. | pmid:25574111 |
| Boltin D et al. | Trends in secondary antibiotic resistance of Helicobacter pylori from 2007 to 2014: has the tide turned? | 2015 | J. Clin. Microbiol. | pmid:25428158 |
| Ersal T et al. | Fatal disseminated infection with Fusarium petroliphilum. | 2015 | Mycopathologia | pmid:25234793 |
| Baumann M et al. | Aquatic toxicity of the macrolide antibiotic clarithromycin and its metabolites. | 2015 | Chemosphere | pmid:25051235 |
| Kakked GA et al. | Pneumobilia with gastric outlet obstruction. | 2015 | BMJ Case Rep | pmid:26552878 |
| Kim SE et al. | Trends in Helicobacter pylori eradication rates by first-line triple therapy and related factors in eradication therapy. | 2015 | Korean J. Intern. Med. | pmid:26552455 |
| Bang CS and Baik GH | Time to learn from the past and prepare for the future in Helicobacter pylori eradication. | 2015 | Korean J. Intern. Med. | pmid:26552453 |
| Blair PW et al. | DRESS syndrome presenting after initiation of mycobacterium avium complex osteomyelitis treatment. | 2015 | BMJ Case Rep | pmid:26438676 |
| Chen KY et al. | Hybrid vs sequential therapy for eradication of Helicobacter pylori in Taiwan: A prospective randomized trial. | 2015 | World J. Gastroenterol. | pmid:26420970 |
| Apiwattankul N et al. | Infections Caused by Rapidly Growing Mycobacteria spp in Children and Adolescents With Cancer. | 2015 | J Pediatric Infect Dis Soc | pmid:26407409 |
| Pea F et al. | Everolimus overexposure in a heart transplant patient receiving clarithromycin for the treatment of pneumonia. | 2015 | Transpl Infect Dis | pmid:26296391 |