clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Prosthesis-Related Infections D016459 7 associated lipids
Fibrosis D005355 23 associated lipids
Tooth Discoloration D014075 7 associated lipids
Sinusitis D012852 9 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with clarithromycin

Download all related citations
Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Grunden JW and Fisher KA Lovastatin-induced rhabdomyolysis possibly associated with clarithromycin and azithromycin. 1997 Jul-Aug Ann Pharmacother pmid:9220046
Tartaglione T Treatment of nontuberculous mycobacterial infections: role of clarithromycin and azithromycin. 1997 Jul-Aug Clin Ther pmid:9377608
Nawarskas JJ et al. Digoxin toxicity secondary to clarithromycin therapy. 1997 Jul-Aug Ann Pharmacother pmid:9220047
al-Humayyd MS Pharmacokinetic interactions between erythromycin, clarithromycin, roxithromycin and phenytoin in the rat. 1997 Mar-Apr Chemotherapy pmid:9084915
Svoboda P et al. Pantoprazole-based dual and triple therapy for the eradication of Helicobacter pylori infection: a randomized controlled trial. 1997 May-Jun Hepatogastroenterology pmid:9222709
Best LM et al. Helicobacter pylori: primary susceptibility to clarithromycin in vitro in Nova Scotia. 1997 May-Jun Can. J. Gastroenterol. pmid:9218854
O'Brien B et al. Cost effectiveness of alternative Helicobacter pylori eradication strategies in the management of duodenal ulcer. 1997 May-Jun Can. J. Gastroenterol. pmid:9218858
Guerriero SE et al. Two cases of clarithromycin-induced digoxin toxicity. 1997 Sep-Oct Pharmacotherapy pmid:9324195
Anzueto A et al. Efficacy of ciprofloxacin and clarithromycin in acute bacterial exacerbations of complicated chronic bronchitis: interim analysis. Bronchitis Study Group. 1997 Sep-Oct Clin Ther pmid:9385486
Kruppa A et al. Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. 1998 Dermatology (Basel) pmid:9621142
Ishii K et al. Comparative study of pharmacokinetic parameters between clarithromycin and erythromycin stearate in relation to their physicochemical properties. 1998 Drug Dev Ind Pharm pmid:15605442
Rosário M et al. [Profile of the resistance to macrolides and imidazoles of Helicobacter pylori in a sample of the Portuguese population]. 1998 Acta Med Port pmid:10192979
Highleyman L FDA issues Hismanal warning. Food and Drug Administration. 1998 BETA pmid:11365263
Kondoh K and Hashiba M [Inhibitory effect of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. 1998 Nippon Jibiinkoka Gakkai Kaiho pmid:9493436
Matsushima T and Miyashita N [Basic and clinical study of Chlamydia pneumoniae infections]. 1998 Nippon Naika Gakkai Zasshi pmid:9922675
Stefansson P et al. Cefuroxime axetil versus clarithromycin in the treatment of acute maxillary sinusitis. 1998 Rhinology pmid:9923060
Huang WH et al. New one-week, low-dose triple therapy for the treatment of duodenal ulcer with Helicobacter pylori infection. 1998 Zhonghua Yi Xue Za Zhi (Taipei) pmid:9745160
Sádaba B et al. Concurrent clarithromycin and cyclosporin A treatment. 1998 J. Antimicrob. Chemother. pmid:9786481
Finkenbine RD and Frye MD Case of psychosis due to prednisone-clarithromycin interaction. 1998 Gen Hosp Psychiatry pmid:9788033
Borody TJ Helicobacter pylori eradication failure--'salvage' therapies needed. 1998 Ital J Gastroenterol Hepatol pmid:9789131
Coudron PE and Stratton CW The bactericidal activity of clarithromycin versus ampicillin alone and in combination with omeprazole and/or bismuth against clarithromycin-susceptible and clarithromycin-resistant strains of Helicobacter pylori. 1998 Diagn. Microbiol. Infect. Dis. pmid:9791756
Niang M et al. [Painful nodular lesions]. 1998 Rev Med Interne pmid:9793156
Saika T et al. [A mechanism of clarithromycin resistance in Helicobacter pylori]. 1998 Kansenshogaku Zasshi pmid:9796191
Hoppe JE and Bryskier A In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). 1998 Antimicrob. Agents Chemother. pmid:9559823
Bazzoli F et al. Efficacy of lansoprazole in eradicating Helicobacter pylori: a meta-analysis. 1998 Helicobacter pmid:9731991
Lanza FL et al. Ranitidine bismuth citrate plus clarithromycin: a dual therapy regimen for patients with duodenal ulcer. 1998 Helicobacter pmid:9731994
Vakil N et al. Clarithromycin-resistant Helicobacter pylori in patients with duodenal ulcer in the United States. 1998 Am. J. Gastroenterol. pmid:9732920
Chu KM et al. A prospective randomized trial comparing the use of omeprazole-based dual and triple therapy for eradication of Helicobacter pylori. 1998 Am. J. Gastroenterol. pmid:9732921
Lamouliatte H et al. Dual therapy using a double dose of lansoprazole with amoxicillin versus triple therapy using a double dose of lansoprazole, amoxicillin, and clarithromycin to eradicate Helicobacter pylori infection: results of a prospective randomized open study. 1998 Am. J. Gastroenterol. pmid:9732938
Coudron PE and Stratton CW In-vitro evaluation of nitrofurantoin as an alternative agent for metronidazole in combination antimicrobial therapy against Helicobacter pylori. 1998 J. Antimicrob. Chemother. pmid:9848452
Cadwgan AM et al. Neisseria meningitidis W135 pneumonia with sepicaemia in a nonogenarian. 1998 Scott Med J pmid:9854302
Ouellet D et al. Pharmacokinetic interaction between ritonavir and clarithromycin. 1998 Clin. Pharmacol. Ther. pmid:9797791
Shimoyama T et al. Healing of cimetidine-resistant Ménétrier's disease by eradication of Helicobacter pylori infection. 1998 J. Clin. Gastroenterol. pmid:9855268
Chodosh S et al. Efficacy of oral ciprofloxacin vs. clarithromycin for treatment of acute bacterial exacerbations of chronic bronchitis. The Bronchitis Study Group. 1998 Clin. Infect. Dis. pmid:9798025
Craft JC et al. Clarithromycin resistance and susceptibility patterns of Mycobacterium avium strains isolated during prophylaxis for disseminated infection in patients with AIDS. 1998 Clin. Infect. Dis. pmid:9798037
Shafran SD Clarithromycin prophylaxis for disseminated Mycobacterium avium complex infection--efficacy and acquired resistance. 1998 Clin. Infect. Dis. pmid:9798038
Siu LK et al. Evaluation of a selective transport medium for gastric biopsy specimens to be cultured for Helicobacter pylori. 1998 J. Clin. Microbiol. pmid:9738066
Cestari R Ranitidine bismuth citrate (RBC) based triple therapy for 7 days is more effective than RBC plus clarithromycin for 14 days in dyspeptic patients with Helicobacter pylori infection. H. Pylori Lombardy Group. 1998 Aliment. Pharmacol. Ther. pmid:9798804
Spadaccini A et al. Triple regimens using lansoprazole or ranitidine bismuth citrate for Helicobacter pylori eradication. 1998 Aliment. Pharmacol. Ther. pmid:9798805
Sevin E et al. Co-detection of Helicobacter pylori and of its resistance to clarithromycin by PCR. 1998 FEMS Microbiol. Lett. pmid:9742711
Bortolotti M et al. Effects of oral clarithromycin and amoxycillin on interdigestive gastrointestinal motility of patients with functional dyspepsia and Helicobacter pylori gastritis. 1998 Aliment. Pharmacol. Ther. pmid:9798808
Hynes B Contact granulomas. 1998 J Otolaryngol pmid:9800633
Fischer BP et al. [Tsutsugamushi fever. Rare rickettsiosis after a stay in the Philippines]. 1998 Dtsch. Med. Wochenschr. pmid:9615696
Torresani C Clarithromycin: a new perspective in rosacea treatment. 1998 Int. J. Dermatol. pmid:9620480
Kashuba AD and Amsden GW Bronchopulmonary pharmacokinetics of clarithromycin and azithromycin. 1998 Antimicrob. Agents Chemother. pmid:9527816
Tsuneoka H et al. [Sensitivity of Helicobacter pylori to amoxicillin and clarythromycin with special reference to eradication therapy]. 1998 Kansenshogaku Zasshi pmid:9621560
Hahn DL et al. Evidence for Chlamydia pneumoniae infection in steroid-dependent asthma. 1998 Ann. Allergy Asthma Immunol. pmid:9475566
Butt AA Cervical adenitis due to Mycobacterium fortuitum in patients with acquired immunodeficiency syndrome. 1998 Am. J. Med. Sci. pmid:9427575
Sonnenberg A et al. Cost savings in duodenal ulcer therapy through Helicobacter pylori eradication compared with conventional therapies: results of a randomized, double-blind, multicenter trial. Gastrointestinal Utilization Trial Study Group. 1998 Arch. Intern. Med. pmid:9570170
Dal Bo' N et al. Low dose of clarithromycin in triple therapy for the eradication of Helicobacter pylori: one or two weeks? 1998 J. Gastroenterol. Hepatol. pmid:9570242
Blum AL et al. Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin Effect One Year after Treatment (OCAY) Study Group. 1998 N. Engl. J. Med. pmid:9862942
Maeda S et al. Helicobacter pylori specific nested PCR assay for the detection of 23S rRNA mutation associated with clarithromycin resistance. 1998 Gut pmid:9863474
Dhawan VK et al. Vancomycin-resistant enterococcal colonization in nonhospitalized HIV-infected patients. 1998 West. J. Med. pmid:9830355
Lasko B et al. Efficacy and safety of oral levofloxacin compared with clarithromycin in the treatment of acute sinusitis in adults: a multicentre, double-blind, randomized study. The Canadian Sinusitis Study Group. 1998 J. Int. Med. Res. pmid:10399110
Valsecchi R and Pigatto P Chronic urticaria and Helicobacter pylori. 1998 Acta Derm. Venereol. pmid:9833044
van Haarst AD et al. The influence of cisapride and clarithromycin on QT intervals in healthy volunteers. 1998 Clin. Pharmacol. Ther. pmid:9834046
Xia HH et al. Metronidazole- and clarithromycin-resistant Helicobacter pylori in dyspeptic patients in western Sydney as determined by testing multiple isolates from different gastric sites. 1998 J. Gastroenterol. Hepatol. pmid:9835322
Borody TJ et al. Eradication therapies for Helicobacter pylori. 1998 J. Gastroenterol. pmid:9840019
Moayyedi P et al. Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. 1998 J. Gastroenterol. pmid:9840021
Ohkusa T et al. Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial. 1998 Ann. Intern. Med. pmid:9841603
Kato S et al. Safety and efficacy of one-week triple therapy for eradicating Helicobacter pylori in children. 1998 Helicobacter pmid:9844069
Iino Y et al. [Immunohistochemical study of the paranasal sinus mucosa of patients being treated with macrolide antibiotics--effects of antigen-presenting cells on the expression of a costimulator]. 1998 Jpn J Antibiot pmid:9597477
Salgado CG et al. [Study on the effects of macrolide antibiotics on the expression of B7-1, B7-2, and CD40 on epidermal Langerhans cells]. 1998 Jpn J Antibiot pmid:9597478
Isono K et al. [Effects of macrolide antibiotics on neutrophil infiltration into the airway mucosa and ICAM-1 expression]. 1998 Jpn J Antibiot pmid:9597480
Enomoto F et al. [Changes in adhesion molecule expressions in neutrophils caused by new macrolide administration]. 1998 Jpn J Antibiot pmid:9597482
Ieshiro R et al. [Effect of clarithromycin in extending the life expectancy of patients with non-small-cell lung cancer--the second report]. 1998 Jpn J Antibiot pmid:9597484
Sakamoto M et al. [Efficacy of clarithromycin (CAM) in patients with inoperable non-small-cell lung cancer]. 1998 Jpn J Antibiot pmid:9597485
Kusuhara H et al. Evaluation of combined antibiotic-omeprazole therapies in Helicobacter pylori-infected Mongolian gerbils. 1998 J. Gastroenterol. pmid:9497215
Dubois A et al. Cure of Helicobacter pylori infection by omeprazole-clarithromycin-based therapy in non-human primates. 1998 J. Gastroenterol. pmid:9497216
Hocqueloux L et al. Pulmonary Mycobacterium avium complex disease without dissemination in HIV-infected patients. 1998 Chest pmid:9498982
Malfertheiner P and Blum AL [Helicobacter pylori infection and ulcer]. 1998 Chirurg pmid:9576033
Lee KL et al. QT prolongation and Torsades de Pointes associated with clarithromycin. 1998 Am. J. Med. pmid:9576415
Schwartz H et al. Triple versus dual therapy for eradicating Helicobacter pylori and preventing ulcer recurrence: a randomized, double-blind, multicenter study of lansoprazole, clarithromycin, and/or amoxicillin in different dosing regimens. 1998 Am. J. Gastroenterol. pmid:9576452
Felmingham D et al. Antimicrobial susceptibility of community-acquired lower respiratory tract bacterial pathogens isolated in the UK during the 1995-1996 cold season. 1998 J. Antimicrob. Chemother. pmid:9578171
Tatsis G et al. Efficacy and tolerance of roxithromycin versus clarithromycin in the treatment of lower respiratory tract infections. 1998 J. Antimicrob. Chemother. pmid:9579716
Perng CL et al. One-week triple therapy with lansoprazole, clarithromycin, and metronidazole to cure Helicobacter pylori infection in peptic ulcer disease in Korea. 1998 Dig. Dis. Sci. pmid:9539638
Dobrilla G et al. Ranitidine bismuth citrate with either clarithromycin 1 g/day or 1.5 g/day is equally effective in the eradication of H. pylori and healing of duodenal ulcer. 1998 Aliment. Pharmacol. Ther. pmid:9692703
Harris A Current regimens for treatment of Helicobacter pylori infection. 1998 Br. Med. Bull. pmid:9604443
Doherty TM and Sher A IL-12 promotes drug-induced clearance of Mycobacterium avium infection in mice. 1998 J. Immunol. pmid:9605144
Moayyedi P et al. Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. 1998 J. Gastroenterol. pmid:9605943
Gavura SR and Nusinowitz S Leukocytoclastic vasculitis associated with clarithromycin. 1998 Ann Pharmacother pmid:9606474
Ramon PM et al. [Uveitis, arthralgia and pseudo-jaundice in a HIV seronegative patient due to rifabutin]. 1998 Rev Mal Respir pmid:9608993
Lilley LL and Guanci R A dangerous combination. 1998 Am J Nurs pmid:9612423
Sheu BS et al. One-week proton pump inhibitor-based triple therapy eradicates residual Helicobacter pylori after failed dual therapy. 1998 J. Formos. Med. Assoc. pmid:9585678
Lacy MK et al. Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae. 1998 Int. J. Antimicrob. Agents pmid:9916901
Fera MT et al. Bactericidal activity of lansoprazole and three macrolides against Helicobacter pylori strains tested by the time-kill kinetic method. 1998 Int. J. Antimicrob. Agents pmid:9916902
Holmberg SD et al. Possible effectiveness of clarithromycin and rifabutin for cryptosporidiosis chemoprophylaxis in HIV disease. HIV Outpatient Study (HOPS) Investigators. 1998 JAMA pmid:9459473
Shimoyama T et al. [Antibiotic therapy in eradicating Helicobacter pylori infections]. 1998 Nippon Naika Gakkai Zasshi pmid:9648426
Cecchi R and Torelli E Schönlein-Henoch purpura in association with duodenal ulcer and gastric Helicobacter pylori infection. 1998 J. Dermatol. pmid:9714985
Kimura K and Sato K [Recent topics on Helicobacter pylori--Historic background and problems caused by bacteria]. 1998 Nippon Naika Gakkai Zasshi pmid:9648427
Dore MP et al. Demonstration of unexpected antibiotic resistance of genotypically identical Helicobacter pylori isolates. 1998 Clin. Infect. Dis. pmid:9675458
Aoyama N [Efficacy of antibiotic therapy in eradicating Helicobacter pylori]. 1998 Nippon Naika Gakkai Zasshi pmid:9648439
Sato R et al. [Problems following antibiotic therapy for eradication of Helicobacter pylori]. 1998 Nippon Naika Gakkai Zasshi pmid:9648440
Nakamura T et al. [Topics on Helicobacter pylori (discussion)]. 1998 Nippon Naika Gakkai Zasshi pmid:9648442
Parente F et al. Effects of Helicobacter pylori eradication on gastric function indices in functional dyspepsia. A prospective controlled study. 1998 Scand. J. Gastroenterol. pmid:9648983
Moshkowitz M et al. One-week triple therapy with omeprazole, clarithromycin, and nitroimidazole for Helicobacter pylori infection in children and adolescents. 1998 Pediatrics pmid:9651466
Wiedermann BL Macrolides: clarithromycin and azithromycin. 1998 Pediatr Rev pmid:9654947
Tanahashi T et al. Analysis of the 13C-urea breath test for detection of Helicobacter pylori infection based on the kinetics of delta-13CO2 using laser spectroscopy. 1998 J. Gastroenterol. Hepatol. pmid:9715426
Hashimoto Y [Eradication therapies for Helicobacter pylori]. 1998 Kansenshogaku Zasshi pmid:9695480
Wakasugi H et al. Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein. 1998 Clin. Pharmacol. Ther. pmid:9695727