clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Fibrosis D005355 23 associated lipids
Fistula D005402 8 associated lipids
Foot Diseases D005534 4 associated lipids
Fractures, Open D005597 3 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Gastritis D005756 27 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Gastritis, Hypertrophic D005758 1 associated lipids
Gastroesophageal Reflux D005764 10 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Liu KS et al. Ten day sequential versus 10 day modified bismuth quadruple therapy as empirical firstline and secondline treatment for Helicobacter pylori in Chinese patients: an open label, randomised, crossover trial. 2014 Gut pmid:24295850
Miwa S et al. Efficacy of clarithromycin and ethambutol for Mycobacterium avium complex pulmonary disease. A preliminary study. 2014 Ann Am Thorac Soc pmid:24298907
Tan X and Song Z Human saliva-based quantitative monitoring of clarithromycin by flow injection chemiluminescence analysis: a pharmacokinetic study. 2014 Appl. Biochem. Biotechnol. pmid:24166104
Kakuda TN et al. Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies. 2014 J. Antimicrob. Chemother. pmid:24155058
Seung KJ et al. Salvage therapy for multidrug-resistant tuberculosis. 2014 Clin. Microbiol. Infect. pmid:23991934
Kathariya R et al. Evaluation of subgingivally delivered 0.5% clarithromycin as an adjunct to nonsurgical mechanotherapy in the management of chronic periodontitis: a short-term double blinded randomized control trial. 2014 J Investig Clin Dent pmid:23097216
Bjerre M et al. Osteoprotegerin independently predicts mortality in patients with stable coronary artery disease: the CLARICOR trial. 2014 Scand. J. Clin. Lab. Invest. pmid:25026506
Noh TK et al. Infection with Mycobacterium fortuitum during acupoint embedding therapy. 2014 J. Am. Acad. Dermatol. pmid:24831334
Loreto ES et al. New insights into the in vitro susceptibility of Pythium insidiosum. 2014 Antimicrob. Agents Chemother. pmid:25223997
Kim SY et al. Changes in serum immunomolecules during antibiotic therapy for Mycobacterium avium complex lung disease. 2014 Clin. Exp. Immunol. pmid:24354934
De Francesco V et al. Change of point mutations in Helicobacter pylori rRNA associated with clarithromycin resistance in Italy. 2014 J. Med. Microbiol. pmid:24344205
Yamada K et al. Azithromycin inhibits MUC5AC induction via multidrug-resistant Acinetobacter baumannii in human airway epithelial cells. 2014 Pulm Pharmacol Ther pmid:24910464
Lee JY et al. Factors affecting first-line triple therapy of Helicobacter pylori including CYP2C19 genotype and antibiotic resistance. 2014 Dig. Dis. Sci. pmid:24599773
Zhao HM et al. [Clinical effect of triple therapy combined with Saccharomyces boulardii in the treatment of Helicobacter pylori infection in children]. 2014 Zhongguo Dang Dai Er Ke Za Zhi pmid:24661511
Ohe M and Hashino S Successful treatment of primary immune thrombocytopenia in aged patients using clarithromycin. 2014 J. Formos. Med. Assoc. pmid:24630039
Peedikayil MC et al. Levofloxacin-based first-line therapy versus standard first-line therapy for Helicobacter pylori eradication: meta-analysis of randomized controlled trials. 2014 PLoS ONE pmid:24465624
Yoshida N et al. A cross-sectional investigation of the quality of selected medicines in Cambodia in 2010. 2014 BMC Pharmacol Toxicol pmid:24593851
Vu DH et al. Simultaneous determination of rifampicin, clarithromycin and their metabolites in dried blood spots using LC-MS/MS. 2014 Talanta pmid:24607103
Zaiem A et al. Clarithromycin induced psoriasis in a 37-year old man. 2014 Curr Drug Saf pmid:24410388
de Masson A et al. Cavitary pulmonary disease in a patient treated with natalizumab. 2014 Presse Med pmid:24742610
Methaneethorn J et al. A pharmacokinetic drug-drug interaction model of simvastatin and clarithromycin in humans. 2014 Conf Proc IEEE Eng Med Biol Soc pmid:25571290
Kim SY et al. [Ten day concomitant therapy is superior to ten day sequential therapy for Helicobacter pylori eradication]. 2014 Korean J Gastroenterol pmid:25420735
Mustafa G and Necati B Clarithromycin-associated rhabdomyolysis in an infant. 2014 J Clin Rheumatol pmid:25417692
Hashim H et al. Eradication of Helicobacter pylori infection improves levodopa action, clinical symptoms and quality of life in patients with Parkinson's disease. 2014 PLoS ONE pmid:25411976
Yangco BG et al. Is primary mycobacterium avium complex prophylaxis necessary in patients with CD4 <50 cells/μL who are virologically suppressed on cART? 2014 AIDS Patient Care STDS pmid:24833016
Martos M et al. Clarithromycin for first-line treatment of Helicobacter pylori infection after culture in high-resistance regions. 2014 Eur J Gastroenterol Hepatol pmid:25229983
Veraldi S et al. Treatment of sporotrichoid fish tank granuloma with pulsed clarithromycin. 2014 Dermatology (Basel) pmid:25228273
Phillips RO et al. Reply to "compliance with antimicrobial therapy for buruli ulcer". 2014 Antimicrob. Agents Chemother. pmid:25225343
Klis S et al. Compliance with antimicrobial therapy for buruli ulcer. 2014 Antimicrob. Agents Chemother. pmid:25225342
Mitui M et al. Novel Helicobacter pylori sequencing test identifies high rate of clarithromycin resistance. 2014 J. Pediatr. Gastroenterol. Nutr. pmid:25222804
Patel SK et al. Helicobacter pylori is not eradicated after triple therapy: a nested PCR based study. 2014 Biomed Res Int pmid:25054141
Elkhatib W and Noreddin A Efficacy of ciprofloxacin-clarithromycin combination against drug-resistant Pseudomonas aeruginosa mature biofilm using in vitro experimental model. 2014 Microb. Drug Resist. pmid:25050970
Ohe M and Bohgaki T Successful treatment with clarithromycin for patients with polymyalgia rheumatica. 2014 Korean J. Intern. Med. pmid:25045305
Martin JH and Coombes I Mortality from common drug interactions systems, knowledge and clinical reasoning to optimise prescribing. 2014 Intern Med J pmid:25041768
Bansal S and Chhibber S Phytochemical-induced reduction of pulmonary inflammation during Klebsiella pneumoniae lung infection in mice. 2014 J Infect Dev Ctries pmid:25022293
Fouka E et al. Low-dose clarithromycin therapy modulates Th17 response in non-cystic fibrosis bronchiectasis patients. 2014 Lung pmid:25016929
Dalbøge CS et al. Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. 2014 J. Cyst. Fibros. pmid:24035278
Glatz M and Muellegger RR Drug-associated aquagenic wrinkling of the palms in an atopic male patient. 2014 BMJ Case Rep pmid:24903725
DiCicco M et al. In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermedius. 2014 BMC Microbiol. pmid:24886369
Noonan KA et al. Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma. 2014 Cancer Immunol Res pmid:24878583
Gong EJ et al. Meta-analysis of first-line triple therapy for helicobacter pylori eradication in Korea: is it time to change? 2014 J. Korean Med. Sci. pmid:24851029
Jeon HK and Kim GH Does standard triple therapy still have a role in first-line Helicobacter pylori eradication in Korea? 2014 J. Korean Med. Sci. pmid:24851014
Graham DY et al. Rational Helicobacter pylori therapy: evidence-based medicine rather than medicine-based evidence. 2014 Clin. Gastroenterol. Hepatol. pmid:23751282
Lee SH et al. Detection and assessment of clarithromycin inducible resistant strains among Korean Mycobacterium abscessus clinical strains: PCR methods. 2014 J. Clin. Lab. Anal. pmid:24652818
Binh TT et al. Discovery of novel mutations for clarithromycin resistance in Helicobacter pylori by using next-generation sequencing. 2014 J. Antimicrob. Chemother. pmid:24648504
Tursi A et al. Decreasing efficacy of the standard seven-day triple therapy containing amoxycillin and clarithromycin in curing Helicobacter pylori infection in clinical setting in Italy: a 10-year follow-up study. 2014 Panminerva Med pmid:24637473
Wei Z et al. Rome III criteria cannot distinguish patients with chronic gastritis from those functional dyspepsia patients. 2014 Helicobacter pmid:24617669
Wu JY et al. Feasibility of shortening 14-day hybrid therapy while maintaining an excellent Helicobacter pylori eradication rate. 2014 Helicobacter pmid:24612093
Settin A et al. Cure rate of Helicobacter pylori infection in Egyptian children related to CYP2C19 gene polymorphism. 2014 Indian J Gastroenterol pmid:24610583
Garza-González E et al. A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication. 2014 World J. Gastroenterol. pmid:24587620