clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Vlachogianni P et al. | Mycobacterium avium Auricular Infection in an Apparent Immunocompetent Patient: A Case Report. | Folia Med (Plovdiv) | pmid:27552790 | |
Aoki D et al. | Roxithromycin inhibits angiogenesis of human hepatoma cells in vivo by suppressing VEGF production. | Anticancer Res. | pmid:15816530 | |
Koh WJ et al. | Nontuberculous mycobacterial pulmonary diseases in immunocompetent patients. | Korean J Radiol | pmid:12271159 | |
Mégraud F | [Helicobacter pylori infection: Review and practice]. | Presse Med | pmid:20627443 | |
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Yoon HJ et al. | Nontuberculous mycobacterial tenosynovitis in the hand: two case reports with the MR imaging findings. | Korean J Radiol | pmid:22043158 | |
Mégraud F | Failed Eradication for Helicobacter pylori. What Should Be Done? | Dig Dis | pmid:27332826 | |
Wani FA et al. | Antibiotic resistance in : A mutational analysis from a tertiary care hospital in Kashmir, India. | Indian J Med Microbiol | pmid:30084422 | |
Jeon JS et al. | Detection of clarithromycin-resistant by polymerase chain reaction using residual samples from rapid urease test. | Indian J Med Microbiol | pmid:29063887 | |
Hu JL et al. | Optimized high-dose amoxicillin-proton-pump inhibitor dual therapies fail to achieve high cure rates in China. | Saudi J Gastroenterol | pmid:28937021 | |
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Horiguchi T et al. | Antibacterial activity and clinical efficacy of sparfloxacin in Mycobacterium avium-intracellulare complex infection. | J. Int. Med. Res. | pmid:15458286 | |
Zhang SH et al. | The effect of virulence genotypes of on eradication therapy in children. | Saudi J Gastroenterol | pmid:29652033 | |
Christodoulou C et al. | Quetiapine and clarithromycin-induced neuroleptic malignant syndrome. | Clin Neuropharmacol | pmid:25580921 | |
Al Majid FM | Peritonitis due to Mycobacterium fortuitum following gastric banding. | Saudi J Gastroenterol | pmid:20339182 | |
Shokrzadeh L et al. | Antibiotic susceptibility profile of Helicobacter pylori isolated from the dyspepsia patients in Tehran, Iran. | Saudi J Gastroenterol | pmid:21727733 | |
Solé López J et al. | [Consumption of antibiotics and their possible relationship with bacterial resistance in the "Costa de Ponent" health region: analysis of evolution through the initial and end periods of the last decade]. | Aten Primaria | pmid:15274900 | |
Issa H et al. | Bleeding duodenal ulcer after Roux-en-Y gastric bypass surgery: the value of laparoscopic gastroduodenoscopy. | Ann Saudi Med | pmid:20103961 | |
Hasan SR et al. | Short-duration furazolidone therapy in combination with amoxicillin, bismuth subcitrate, and omeprazole for eradication of Helicobacter pylori. | Saudi J Gastroenterol | pmid:20065568 | |
Lew EA | Clarithromycin, lansoprazole, and metronidazole eradicated Helicobacter pylori infection in chronic renal insufficiency. | ACP J. Club | pmid:15122860 | |
Lindeboom JA | Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria. | Pediatr Dermatol | pmid:26823205 | |
Beck J | Efficacy of esomeprazole in patients with acid-peptic disorders. | Gastroenterol Nurs | pmid:15082946 | |
pmid: | ||||
Ling TK et al. | In vitro activity and post-antibiotic effect of quinupristin/dalfopristin (Synercid). | Chemotherapy | pmid:11399860 | |
Gokhale NS | Medical management approach to infectious keratitis. | Indian J Ophthalmol | pmid:18417822 | |
Varghese B et al. | First case report of chronic pulmonary lung disease caused by Mycobacterium abscessus in two immunocompetent patients in Saudi Arabia. | Ann Saudi Med | pmid:22588446 | |
Bernstein JM and Bacheller CD | It's on the tip of my tongue. | Skinmed | pmid:16687984 | |
Alboraie M et al. | Quadruple therapy versus standard triple therapy for eradication of Helicobacter pylori in Kuwait. | Arab J Gastroenterol | pmid:26611765 | |
Chang NL et al. | Clarithromycin-Induced Torsades de Pointes. | Am J Ther | pmid:25057773 | |
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Alkim H et al. | Role of Bismuth in the Eradication of Helicobacter pylori. | Am J Ther | pmid:26808355 | |
Gościniak G et al. | Frequency of infection with Helicobacter pylori isolates of different antimicrobial profiles in children and adolescents: A preliminary study. | Adv Clin Exp Med | pmid:28791844 | |
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Seitz CS et al. | Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. | Allergol Immunopathol (Madr) | pmid:21269750 | |
Moreira A et al. | Is Helicobacter pylori infection associated with chronic idiopathic urticaria? | Allergol Immunopathol (Madr) | pmid:12890412 | |
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Chen YI and Fallone CA | A 14-day course of triple therapy is superior to a 10-day course for the eradication of Helicobacter pylori: A Canadian study conducted in a 'real world' setting. | Can J Gastroenterol Hepatol | pmid:26301332 |