| MeSH term | MeSH ID | Detail |
|---|---|---|
| Wound Infection | D014946 | 12 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Gram-Negative Bacterial Infections | D016905 | 16 associated lipids |
| Periodontal Pocket | D010514 | 9 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Neuromuscular Diseases | D009468 | 10 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Nasal Polyps | D009298 | 26 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Miftahussurur M et al. | Emerging Helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal. | 2016 | BMC Microbiol. | pmid:27809767 |
| Plate A | [Not Available]. | 2016 | Praxis (Bern 1994) | pmid:27606919 |
| Huh CW et al. | Early Attempts to Eradicate Helicobacter pylori after Endoscopic Resection of Gastric Neoplasm Significantly Improve Eradication Success Rates. | 2016 | PLoS ONE | pmid:27588679 |
| Watanabe M et al. | Saturated fatty acids and fatty acid esters promote the polymorphic transition of clarithromycin metastable form I crystal. | 2016 | Int J Pharm | pmid:27553780 |
| Nagashima A et al. | Clarithromycin Suppresses Chloride Channel Accessory 1 and Inhibits Interleukin-13-Induced Goblet Cell Hyperplasia in Human Bronchial Epithelial Cells. | 2016 | Antimicrob. Agents Chemother. | pmid:27550358 |
| Büchsel M et al. | A case of septic arthritis caused by a Mycoplasma salivarium strain resistant towards Ciprofloxacin and Clarithromycin in a patient with chronic lymphatic leukemia. | 2016 | Diagn. Microbiol. Infect. Dis. | pmid:27342785 |
| Lin LC et al. | Nonbismuth concomitant quadruple therapy for Helicobacter pylori eradication in Chinese regions: A meta-analysis of randomized controlled trials. | 2016 | World J. Gastroenterol. | pmid:27340362 |
| Abd-Elsalam S et al. | A 2-week Nitazoxanide-based quadruple treatment as a rescue therapy for Helicobacter pylori eradication: A single center experience. | 2016 | Medicine (Baltimore) | pmid:27310977 |
| De Francesco V et al. | Two-week Triple Therapy with either Standard or High-dose Esomeprazole for First-line H. pylori Eradication. | 2016 | J Gastrointestin Liver Dis | pmid:27308644 |
| Zollner-Schwetz I et al. | Primary resistance of Helicobacter pylori is still low in Southern Austria. | 2016 | Int. J. Med. Microbiol. | pmid:27134190 |
| Georgopoulos SD et al. | Randomized clinical trial comparing ten day concomitant and sequential therapies for Helicobacter pylori eradication in a high clarithromycin resistance area. | 2016 | Eur. J. Intern. Med. | pmid:27134145 |
| Kim JS et al. | Sequential Therapy versus Triple Therapy for the First Line Treatment of Helicobacter pylori in Korea: A Nationwide Randomized Trial. | 2016 | Gut Liver | pmid:27114421 |
| Manniello MD et al. | Aerodynamic properties, solubility and in vitro antibacterial efficacy of dry powders prepared by spray drying: Clarithromycin versus its hydrochloride salt. | 2016 | Eur J Pharm Biopharm | pmid:27106605 |
| Seyama S et al. | Clarithromycin Resistance Mechanisms of Epidemic β-Lactamase-Nonproducing Ampicillin-Resistant Haemophilus influenzae Strains in Japan. | 2016 | Antimicrob. Agents Chemother. | pmid:26953210 |
| Ji Z et al. | The Association of Age and Antibiotic Resistance of Helicobacter Pylori: A Study in Jiaxing City, Zhejiang Province, China. | 2016 | Medicine (Baltimore) | pmid:26937912 |
| Murakami K et al. | Vonoprazan, a novel potassium-competitive acid blocker, as a component of first-line and second-line triple therapy for Helicobacter pylori eradication: a phase III, randomised, double-blind study. | 2016 | Gut | pmid:26935876 |
| Park JY et al. | Helicobacter pylori Clarithromycin Resistance and Treatment Failure Are Common in the USA. | 2016 | Dig. Dis. Sci. | pmid:26923948 |
| Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
| Iyer G and Alexander GC | Cardiovascular risks associated with clarithromycin. | 2016 | BMJ | pmid:26769796 |
| Wong AY et al. | Cardiovascular outcomes associated with use of clarithromycin: population based study. | 2016 | BMJ | pmid:26768836 |
| Hirama T et al. | PCR-Based Rapid Identification System Using Bridged Nucleic Acids for Detection of Clarithromycin-Resistant Mycobacterium avium-M. intracellulare Complex Isolates. | 2016 | J. Clin. Microbiol. | pmid:26739154 |
| Radheshi E et al. | Postmortem diagnosis of anaphylaxis in presence of decompositional changes. | 2016 | J Forensic Leg Med | pmid:26735898 |
| Hollitt A et al. | Cat scratch disease of the parotid gland. | 2016 | Arch. Dis. Child. | pmid:26403943 |
| Sprague J et al. | Cutaneous infection with Mycobacterium kansasii in a patient with myelodysplastic syndrome and Sweet syndrome. | 2015 | Cutis | pmid:26244358 |
| Sharara AI et al. | Letter: clarithromycin dose for H. pylori therapy remains unresolved--authors' reply. | 2015 | Aliment. Pharmacol. Ther. | pmid:26238584 |
| Graham DY and Gisbert JP | Letter: clarithromycin dose for H. pylori therapy remains unresolved. | 2015 | Aliment. Pharmacol. Ther. | pmid:26238583 |
| Chou HW et al. | Risks of cardiac arrhythmia and mortality among patients using new-generation macrolides, fluoroquinolones, and β-lactam/β-lactamase inhibitors: a Taiwanese nationwide study. | 2015 | Clin. Infect. Dis. | pmid:25409476 |
| Jeong BH et al. | Intermittent antibiotic therapy for nodular bronchiectatic Mycobacterium avium complex lung disease. | 2015 | Am. J. Respir. Crit. Care Med. | pmid:25393520 |
| Hill FJ et al. | From a fish tank injury to hospital haemodialysis: the serious consequences of drug interactions. | 2015 | BMJ Case Rep | pmid:26106178 |
| Yu T et al. | Study on clarithromycin lactobionate based dual selector systems for the enantioseparation of basic drugs in capillary electrophoresis. | 2015 | J Sep Sci | pmid:26097042 |
| Trotti LM et al. | Clarithromycin in γ-aminobutyric acid-Related hypersomnolence: A randomized, crossover trial. | 2015 | Ann. Neurol. | pmid:26094838 |
| AktaÅŸ B et al. | The impact of amalgam dental fillings on the frequency of Helicobacter pylori infection and H. pylori eradication rates in patients treated with concomitant, quadruple, and levofloxacin-based therapies. | 2015 | Eur J Gastroenterol Hepatol | pmid:25919773 |
| Mitsui Y et al. | Gastric inflammatory fibroid polyp morphologically changed by Helicobacter pylori eradication. | 2015 | Clin J Gastroenterol | pmid:25733031 |
| Ben Chaabane N and Al-Adhba HS | Ciprofloxacin-containing versus clarithromycin-containing sequential therapy for Helicobacter pylori eradication: A randomized trial. | 2015 | Indian J Gastroenterol | pmid:25721770 |
| Townsell MY et al. | Pathology in practice. Canine distemper virus disease in a dog. | 2015 | J. Am. Vet. Med. Assoc. | pmid:25719842 |
| Scherübl H et al. | [What is new in treating Helicobacter pylori infection?]. | 2015 | Dtsch. Med. Wochenschr. | pmid:25704525 |
| Blix HS et al. | Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance? | 2015 | Epidemiol. Infect. | pmid:25388750 |
| Brown-Elliott BA et al. | Absence of a functional erm gene in isolates of Mycobacterium immunogenum and the Mycobacterium mucogenicum group, based on in vitro clarithromycin susceptibility. | 2015 | J. Clin. Microbiol. | pmid:25568437 |
| Amiri M | Impact of Helicobacter pylori Eradication Therapy on Platelet Counts in Patients With Chronic Idiopathic Thrombocytopenic Purpura. | 2015 | Glob J Health Sci | pmid:26925898 |
| Zhang L et al. | [Minocycline quadruple versus tailored therapy in retreatment of Helicobacter pylori infection]. | 2015 | Zhonghua Nei Ke Za Zhi | pmid:26887366 |
| Park JB et al. | Modulation of microenvironmental pH and utilization of alkalizers in crystalline solid dispersion for enhanced solubility and stability of clarithromicin. | 2015 | Arch. Pharm. Res. | pmid:25213008 |
| Anton E et al. | Randomized Trial of Clarithromycin for Mediterranean Spotted Fever. | 2015 | Antimicrob. Agents Chemother. | pmid:26711765 |
| Winters N et al. | Efficacy and safety of World Health Organization group 5 drugs for multidrug-resistant tuberculosis treatment. | 2015 | Eur. Respir. J. | pmid:26381514 |
| John A et al. | Does emerging Clarithromycin resistance signal an obituary to empirical standard triple therapy for Helicobacter pylori infection? | 2015 | Indian J Gastroenterol | pmid:26541342 |
| Mel-Hennawi D and Ahmed MR | Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion. | 2015 | J Laryngol Otol | pmid:26521817 |
| Parra D et al. | In vitro efficacy of daptomycin and teicoplanin combined with ethanol, clarithromycin or gentamicin as catheter lock solutions. | 2015 | BMC Microbiol. | pmid:26518881 |
| Xing J et al. | The application of high-resolution mass spectrometry-based data-mining tools in tandem to metabolite profiling of a triple drug combination in humans. | 2015 | Anal. Chim. Acta | pmid:26515003 |
| Weiss S et al. | Efficacy of Single and Combined Antibiotic Treatments of Anthrax in Rabbits. | 2015 | Antimicrob. Agents Chemother. | pmid:26392505 |
| Agrawal V et al. | A Case of Hypotension and Bradycardia Precipitated by Drug Interaction of Clarithromycin and Calcium-Channel Blocker. | 2015 | J Am Geriatr Soc | pmid:26389998 |
| Hauser G et al. | Probiotics for standard triple Helicobacter pylori eradication: a randomized, double-blind, placebo-controlled trial. | 2015 | Medicine (Baltimore) | pmid:25929897 |