clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Wound Infection D014946 12 associated lipids
Bacteriuria D001437 7 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Periodontal Pocket D010514 9 associated lipids
Ischemia D007511 18 associated lipids
Neuromuscular Diseases D009468 10 associated lipids
Peptic Ulcer D010437 19 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Periodontitis D010518 22 associated lipids
Nasal Polyps D009298 26 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Griffith DE Nontuberculous mycobacteria. 1997 Curr Opin Pulm Med pmid:9193860
Villanueva A et al. Report on an outbreak of postinjection abscesses due to Mycobacterium abscessus, including management with surgery and clarithromycin therapy and comparison of strains by random amplified polymorphic DNA polymerase chain reaction. 1997 Clin. Infect. Dis. pmid:9195073
Gabl M et al. Flexor tenosynovitis in the hand caused by Mycobacterium malmoense: a case report. 1997 J Hand Surg Am pmid:9195437
Rubin BK et al. Effect of clarithromycin on nasal mucus properties in healthy subjects and in patients with purulent rhinitis. 1997 Am. J. Respir. Crit. Care Med. pmid:9196110
Rodvold KA et al. Intrapulmonary steady-state concentrations of clarithromycin and azithromycin in healthy adult volunteers. 1997 Antimicrob. Agents Chemother. pmid:9174209
Lo WC et al. Clarithromycin in the combination therapy for the eradication of Helicobacter pylori in peptic ulcer disease. 1997 Zhonghua Yi Xue Za Zhi (Taipei) pmid:9198292
Fréhel C et al. The phagosomal environment protects virulent Mycobacterium avium from killing and destruction by clarithromycin. 1997 Infect. Immun. pmid:9199452
Katari SR et al. Clinical features of acute reversible tacrolimus (FK 506) nephrotoxicity in kidney transplant recipients. 1997 Clin Transplant pmid:9193849
Waites K et al. In vitro activities of oral antimicrobial agents against penicillin-resistant Streptococcus pneumoniae: implications for outpatient treatment. 1997 South. Med. J. pmid:9191739
Tarlow MJ et al. Future indications for macrolides. 1997 Pediatr. Infect. Dis. J. pmid:9109159
Reed PI and Johnston BJ Treatment of Helicobacter pylori infection. 1997 Biomed. Pharmacother. pmid:9084725
Plemmons RM et al. Osteomyelitis due to Mycobacterium haemophilum in a cardiac transplant patient: case report and analysis of interactions among clarithromycin, rifampin, and cyclosporine. 1997 Clin. Infect. Dis. pmid:9142810
Khan AA et al. Activity of trovafloxacin in combination with other drugs for treatment of acute murine toxoplasmosis. 1997 Antimicrob. Agents Chemother. pmid:9145840
Collins L and Franzblau SG Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium. 1997 Antimicrob. Agents Chemother. pmid:9145860
Lounis N et al. Comparative activities of amikacin against Mycobacterium avium complex in nude and beige mice. 1997 Antimicrob. Agents Chemother. pmid:9145892
Spinzi G et al. Randomized study comparing omeprazole plus amoxycillin versus omeprazole plus clarithromycin for eradication of Helicobacter pylori. 1997 Aliment. Pharmacol. Ther. pmid:9146769
Denys A [Theoretical basis for the antibiotic therapy of the upper part of the respiratory system]. 1997 Otolaryngol Pol pmid:9757681
Kubas G and Gospodarek T [The use of clarithromycin and amoxycillin in pediatric acute otitis media]. 1997 Otolaryngol Pol pmid:9757683
Banerjee DK et al. Experimental evaluation of possible new short-term drug regimens for treatment of multibacillary leprosy. 1997 Antimicrob. Agents Chemother. pmid:9021187
Paar D et al. Life-threatening interaction between clarithromycin and disopyramide. 1997 Lancet pmid:9024381
Wang XM et al. [Time course of disappearance of Helicobacter pylori after topical therapy and new triple therapy]. 1997 Nihon Shokakibyo Gakkai Zasshi pmid:9028149
Macías J et al. Rhodococcus or mycobacterium? An example of misdiagnosis in HIV infection. 1997 AIDS pmid:9030376
Hoppe JE and Tschirner T Comparison of Etest and agar dilution for testing the activity of three macrolides against Bordetella parapertussis. 1997 Diagn. Microbiol. Infect. Dis. pmid:9218920
Pipkin GA et al. Clarithromycin dual therapy regimens for eradication of Helicobacter pylori: a review. 1997 Helicobacter pmid:9421117
Tompkins DS et al. Failed treatment of Helicobacter pylori infection associated with resistance to clarithromycin. 1997 Helicobacter pmid:9421121
Hultén K et al. Combination treatment with ranitidine is highly efficient against Helicobacter pylori despite negative impact of macrolide resistance. 1997 Helicobacter pmid:9421122
Drugs for treatment of peptic ulcers. 1997 Med Lett Drugs Ther pmid:8996458
O'Connor HJ et al. One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit? 1997 Helicobacter pmid:9421124
Matsunaga K et al. [Successful eradication of H. pylori in an elderly patient with gastric cancer after effective UFT-E therapy]. 1997 Gan To Kagaku Ryoho pmid:9422074
Greco S et al. Glossitis, stomatitis, and black tongue with lansoprazole plus clarithromycin and other antibiotics. 1997 Ann Pharmacother pmid:9416400
Stone GG et al. A PCR-oligonucleotide ligation assay to determine the prevalence of 23S rRNA gene mutations in clarithromycin-resistant Helicobacter pylori. 1997 Antimicrob. Agents Chemother. pmid:9056021
Moayyedi P et al. Patient factors that predict failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. 1997 J. Gastroenterol. pmid:9058291
Marone P et al. Rapid drug susceptibility of Mycobacterium avium complex using a fluorescence quenching method. 1997 J Chemother pmid:9269603
Nilius AM et al. Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. 1997 J. Clin. Microbiol. pmid:9163435
Thornsberry C et al. Surveillance of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States in 1996-1997 respiratory season. The Laboratory Investigator Group. 1997 Diagn. Microbiol. Infect. Dis. pmid:9458982
Briant C et al. Pericarditis as a manifestation of Lyme disease. 1997 J Emerg Nurs pmid:9460386
Sánchez-Nuñez ML et al. Clarithromycin in the treatment of cyclosporin-associated gingival hyperplasia. 1997 Nephrol. Dial. Transplant. pmid:9306384
Finkenbine R and Gill HS Case of mania due to prednisone-clarithromycin interaction. 1997 Can J Psychiatry pmid:9307841
Gisbert JP et al. Unhealed duodenal ulcers despite Helicobacter pylori eradication. 1997 Scand. J. Gastroenterol. pmid:9246702
Fuursted K Evaluation of the post-antibiotic effect of six anti-mycobacterial agents against Mycobacterium avium by the Bactec radiometric method. 1997 J. Antimicrob. Chemother. pmid:9249202
Böttger EC et al. Prophylaxis of mycobacterial infection and acquired drug resistance. 1997 J. Antimicrob. Chemother. pmid:9249224
Peloquin CA and Berning SE Advice on treatment of Mycobacterium avium complex infection. 1997 Am J Health Syst Pharm pmid:9161632
OÄŸuz O et al. Conjunctival involvement in familial chronic benign pemphigus (Hailey-Hailey disease). 1997 Int. J. Dermatol. pmid:9169328
Alfandari S et al. Isolated cutaneous Mycobacterium avium complex infection in AIDS. 1997 Int. J. Dermatol. pmid:9169332
Tillenburg B et al. [Helicobacter pylori: pretherapeutic resistance status in Germany (Ruhr area)]. 1997 Z Gastroenterol pmid:9173687
Veldhuyzen van Zanten SJ et al. Helicobacter pylori: new developments and treatments. 1997 CMAJ pmid:9176424
Nakao K et al. Relation of lactoferrin levels in gastric mucosa with Helicobacter pylori infection and with the degree of gastric inflammation. 1997 Am. J. Gastroenterol. pmid:9177520
Langtry HD and Brogden RN Clarithromycin. A review of its efficacy in the treatment of respiratory tract infections in immunocompetent patients. 1997 Drugs pmid:9179528
Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group. 1997 Gut pmid:9274464
Kundu S et al. Clarithromycin-induced ventricular tachycardia. 1997 Ann Emerg Med pmid:9326871