| MeSH term | MeSH ID | Detail |
|---|---|---|
| Wound Infection | D014946 | 12 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Gram-Negative Bacterial Infections | D016905 | 16 associated lipids |
| Periodontal Pocket | D010514 | 9 associated lipids |
| Ischemia | D007511 | 18 associated lipids |
| Neuromuscular Diseases | D009468 | 10 associated lipids |
| Peptic Ulcer | D010437 | 19 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Periodontitis | D010518 | 22 associated lipids |
| Nasal Polyps | D009298 | 26 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vernet Vernet M et al. | [Analysis of indications and diagnosis of the gastroscopies requested by primary care physicians]. | 2000 | Aten Primaria | pmid:10795440 |
| Boyanova L et al. | Primary and combined resistance to four antimicrobial agents in Helicobacter pylori in Sofia, Bulgaria. | 2000 | J. Med. Microbiol. | pmid:10798553 |
| Boruchoff SE et al. | The steady-state disposition of indinavir is not altered by the concomitant administration of clarithromycin. | 2000 | Clin. Pharmacol. Ther. | pmid:10801243 |
| Azuma T et al. | Pharmacokinetics of clarithromycin in Helicobacter pylori eradication therapy in patients with liver cirrhosis. | 2000 | Aliment. Pharmacol. Ther. | pmid:10807427 |
| Suzuki H et al. | Prognostic factors of chronic rhinosinusitis under long-term low-dose macrolide therapy. | 2000 May-Jun | ORL J. Otorhinolaryngol. Relat. Spec. | pmid:10810255 |
| Rhee CS et al. | Effects of clarithromycin on rheological properties of nasal mucus in patients with chronic sinusitis. | 2000 | Ann. Otol. Rhinol. Laryngol. | pmid:10823478 |
| Zuckerman JM | The newer macrolides: azithromycin and clarithromycin. | 2000 | Infect. Dis. Clin. North Am. | pmid:10829265 |
| Flockhart DA et al. | Studies on the mechanism of a fatal clarithromycin-pimozide interaction in a patient with Tourette syndrome. | 2000 | J Clin Psychopharmacol | pmid:10831018 |
| Spiegel JR et al. | Prolonged ulcerative laryngitis. | 2000 | Ear Nose Throat J | pmid:10832196 |
| Miyashita N et al. | In vitro susceptibility of 7.5-kb common plasmid-free Chlamydia trachomatis strains. | 2000 | Microbiol. Immunol. | pmid:10832970 |
| Gisbert JP et al. | One-week therapy with pantoprazole versus ranitidine bismuth citrate plus two antibiotics for Helicobacter pylori eradication. | 2000 | Eur J Gastroenterol Hepatol | pmid:10833090 |
| Kaushik SP and Vu C | Helicobacter pylori eradication with lansoprazole, amoxycillin and clarithromycin: testing an ideal regimen in a multicultural south east Asian population and examining factors potentially influencing eradication. | 2000 | Aust N Z J Med | pmid:10833116 |
| Laine L et al. | Endoscopic biopsy requirements for post-treatment diagnosis of Helicobacter pylori. | 2000 | Gastrointest. Endosc. | pmid:10840297 |
| Romero Gómez M et al. | [Usefulness of Helicobacter pylori antigen detection in stools in the diagnosis of infection and confirming eradication after treatment]. | 2000 | Med Clin (Barc) | pmid:10846675 |
| Baños F et al. | [Effectiveness of omeprazole, clarithromycin and amoxycillin therapy to eradicate Helicobacter pylori in patients with active peptic ulcer. Preliminary results of GENPY study]. | 2000 | Med Clin (Barc) | pmid:10846695 |
| Zullo A et al. | A new highly effective short-term therapy schedule for Helicobacter pylori eradication. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848654 |
| Moayyedi P et al. | The effectiveness of omeprazole, clarithromycin and tinidazole in eradicating Helicobacter pylori in a community screen and treat programme. Leeds Help Study Group. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848655 |
| Katelaris PH et al. | Randomized trial of omeprazole and metronidazole with amoxycillin or clarithromycin for Helicobacter pylori eradication, in a region of high primary metronidazole resistance: the HERO study. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848659 |
| Ammon S et al. | Influence of age on the steady state disposition of drugs commonly used for the eradication of Helicobacter pylori. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848660 |
| Leiper K et al. | Open label trial of oral clarithromycin in active Crohn's disease. | 2000 | Aliment. Pharmacol. Ther. | pmid:10848665 |
| Bhasin DK et al. | Comparison of seven and fourteen days of lansoprazole, clarithromycin, and amoxicillin therapy for eradication of Helicobacter pylori: a report from India. | 2000 | Helicobacter | pmid:10849056 |
| Nagahara A et al. | Addition of metronidazole to rabeprazole-amoxicillin-clarithromycin regimen for Helicobacter pylori infection provides an excellent cure rate with five-day therapy. | 2000 | Helicobacter | pmid:10849057 |
| Hammerschlag MR and Roblin PM | Microbiologic efficacy of moxifloxacin for the treatment of community-acquired pneumonia due to Chlamydia pneumoniae. | 2000 | Int. J. Antimicrob. Agents | pmid:10854812 |
| Hirschl AM et al. | In vitro activities of linezolid alone and in combination with amoxicillin, clarithromycin, and metronidazole against Helicobacter pylori. | 2000 | Antimicrob. Agents Chemother. | pmid:10858365 |
| Miltner EC and Bermudez LE | Mycobacterium avium grown in Acanthamoeba castellanii is protected from the effects of antimicrobials. | 2000 | Antimicrob. Agents Chemother. | pmid:10858369 |
| Drago L et al. | Comparative effect of thiamphenicol glycinate, thiamphenicol glycinate N-acetylcysteinate, amoxicillin plus clavulanic acid, ceftriaxone and clarithromycin on pulmonary clearance of Haemophilus influenzae in an animal model. | 2000 Jul-Aug | Chemotherapy | pmid:10859433 |
| Mikasa K | [Study of effects and mechanisms of macrolide as biological response modifier for lung cancer treatment]. | 2000 | Jpn J Antibiot | pmid:10868303 |
| Fraser AG et al. | Helicobacter pylori treatment and antibiotic susceptibility: results of a five-year audit. | 1999 | Aust N Z J Med | pmid:10868529 |
| Amayasu H et al. | Clarithromycin suppresses bronchial hyperresponsiveness associated with eosinophilic inflammation in patients with asthma. | 2000 | Ann. Allergy Asthma Immunol. | pmid:10875487 |
| Maggiolo F et al. | In-vitro activity of moxifloxacin combined with other antibacterials against methicillin-resistant Staphylococcus aureus. | 2000 | J Chemother | pmid:10877512 |
| Suzuki K et al. | [Fibrosing alveolitis following Legionella pneumonia]. | 2000 | Nihon Kokyuki Gakkai Zasshi | pmid:10879037 |
| Erel F et al. | Impact of Helicobacter pylori and Giardia lamblia infections on chronic urticaria. | 2000 Mar-Apr | J Investig Allergol Clin Immunol | pmid:10879997 |
| Delchier JC | [How to eradicate Helicobacter pylori?]. | 1999 | Gastroenterol. Clin. Biol. | pmid:10880913 |
| Yanagihara K et al. | Combination therapy for chronic Pseudomonas aeruginosa respiratory infection associated with biofilm formation. | 2000 | J. Antimicrob. Chemother. | pmid:10882691 |
| Saito K et al. | Effect of Helicobacter pylori eradication on malignant transformation of gastric adenoma. | 2000 | Gastrointest. Endosc. | pmid:10882958 |
| Savarino V et al. | The impact of antibiotic resistance on the efficacy of three 7-day regimens against Helicobacter pylori. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886045 |
| Wang WH et al. | High prevalence of Helicobacter pylori infection with dual resistance to metronidazole and clarithromycin in Hong Kong. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886046 |
| Sung JJ et al. | Atrophy and intestinal metaplasia one year after cure of H. pylori infection: a prospective, randomized study. | 2000 | Gastroenterology | pmid:10889149 |
| Lamouliatte H et al. | [Treatment of Helicobacter pylori infection with lansoprazole 30 mg or 60 mg combined with two antibiotics for duodenal ulcers]. | 2000 | Gastroenterol. Clin. Biol. | pmid:10891736 |
| Toutous-Trellu L et al. | Three cases of cutaneous sarcoidosis: search for bacterial agent by the 16S RNA gene analysis and treatment with antibiotics. | 2000 | Dermatology (Basel) | pmid:10894973 |
| Konno M et al. | Iron-deficiency anemia associated with Helicobacter pylori gastritis. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10896071 |
| Jamal MA et al. | Molecular basis of clarithromycin-resistance in Mycobacterium avium intracellulare complex. | 2000 | Tuber. Lung Dis. | pmid:10897378 |
| Jordan MK et al. | Effects of fluconazole and clarithromycin on rifabutin and 25-O-desacetylrifabutin pharmacokinetics. | 2000 | Antimicrob. Agents Chemother. | pmid:10898693 |
| Kato M et al. | Regional differences in metronidazole resistance and increasing clarithromycin resistance among Helicobacter pylori isolates from Japan. | 2000 | Antimicrob. Agents Chemother. | pmid:10898707 |
| Bortolotti M et al. | Dose-related stimulatory effect of clarithromycin on interdigestive gastroduodenal motility. | 2000 | Digestion | pmid:10899723 |
| Moayyedi P et al. | Effect of population screening and treatment for Helicobacter pylori on dyspepsia and quality of life in the community: a randomised controlled trial. Leeds HELP Study Group. | 2000 | Lancet | pmid:10905240 |
| Miwi H et al. | Comparison of the efficacy of 400mg and 800mg of clarithromycin used with lansoprazole and amoxicillin in eradication regimens for Helicobacter pylori infection in a Japanese population. | 2000 | J. Gastroenterol. | pmid:10905362 |
| McCarty J et al. | Clarithromycin suspension vs penicillin V suspension in children with streptococcal pharyngitis. | 2000 Jan-Feb | Adv Ther | pmid:10915400 |
| Lerner FE et al. | Clarithromycin bioequivalence study of two oral formulations in healthy human volunteers. | 2000 | Int J Clin Pharmacol Ther | pmid:10919343 |
| Frueh BE et al. | Mycobacterium szulgai keratitis. | 2000 | Arch. Ophthalmol. | pmid:10922211 |