| MeSH term | MeSH ID | Detail |
|---|---|---|
| Empyema, Tuberculous | D004654 | 1 associated lipids |
| Tuberculosis, Ocular | D014392 | 1 associated lipids |
| Encephalomyelitis, Acute Disseminated | D004673 | 1 associated lipids |
| Serositis | D012700 | 1 associated lipids |
| Euthyroid Sick Syndromes | D005067 | 1 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Glossitis, Benign Migratory | D005929 | 1 associated lipids |
| Parotid Diseases | D010305 | 1 associated lipids |
| Sacroiliitis | D058566 | 1 associated lipids |
| Achlorhydria | D000126 | 1 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cindoruk M et al. | Influence of H pylori on plasma ghrelin in patients without atrophic gastritis. | 2007 | World J. Gastroenterol. | pmid:17461454 |
| Mesquita MA et al. | One-week dual therapy with ranitidine bismuth citrate and clarithromycin for the treatment of Helicobacter pylori infection in Brazilian patients with peptic ulcer. | 2005 | World J. Gastroenterol. | pmid:15962376 |
| Cosme A et al. | Antimicrobial susceptibility testing before first-line treatment for infection in patients with dual or triple antibiotic resistance. | 2017 | World J. Gastroenterol. | pmid:28566898 |
| Keshavarz AA et al. | Omeprazole-based triple therapy with low-versus high-dose of clarithromycin plus amoxicillin for H pylori eradication in Iranian population. | 2007 | World J. Gastroenterol. | pmid:17352026 |
| Losurdo G et al. | Role of concomitant therapy for eradication: A technical note. | 2016 | World J. Gastroenterol. | pmid:27784977 |
| Robles-Jara C et al. | Is a 7-day Helicobater pylori treatment enough for eradication and inactivation of gastric inflammatory activity? | 2008 | World J. Gastroenterol. | pmid:18473407 |
| Koussoulas V et al. | Evidence for the role of gastric mucosa at the secretion of soluble triggering receptor expressed on myeloid cells (strem-1) in peptic ulcer disease. | 2007 | World J. Gastroenterol. | pmid:17729416 |
| Hwang JJ et al. | Efficacy of moxifloxacin-based sequential therapy for first-line eradication of Helicobacter pylori infection in gastrointestinal disease. | 2015 | World J. Gastroenterol. | pmid:25945019 |
| Lin LC et al. | Nonbismuth concomitant quadruple therapy for Helicobacter pylori eradication in Chinese regions: A meta-analysis of randomized controlled trials. | 2016 | World J. Gastroenterol. | pmid:27340362 |
| Miehlke S et al. | Helicobacter pylori and gastric cancer:current status of the Austrain Czech German gastric cancer prevention trial (PRISMA Study). | 2001 | World J. Gastroenterol. | pmid:11819768 |
| Iannone A et al. | New fecal test for non-invasive detection: A diagnostic accuracy study. | 2018 | World J. Gastroenterol. | pmid:30038469 |
| Matta AJ et al. | Punctual mutations in gene of clarithromycin-resistant in Colombian populations. | 2018 | World J. Gastroenterol. | pmid:29662291 |
| Lee HJ et al. | Concomitant therapy achieved the best eradication rate for Helicobacter pylori among various treatment strategies. | 2015 | World J. Gastroenterol. | pmid:25574111 |
| Brennan DE et al. | Can bacterial virulence factors predict antibiotic resistant infection? | 2018 | World J. Gastroenterol. | pmid:29531461 |
| Mamori S et al. | Age-dependent eradication of Helicobacter pylori in Japanese patients. | 2010 | World J. Gastroenterol. | pmid:20806435 |
| Yoon JH et al. | Trends in the eradication rates of Helicobacter pylori infection for eleven years. | 2012 | World J. Gastroenterol. | pmid:23236238 |
| Campuzano-Maya G | Cure of alopecia areata after eradication of Helicobacter pylori: a new association? | 2011 | World J. Gastroenterol. | pmid:21912461 |
| Hao Q et al. | New mutation points in 23S rRNA gene associated with Helicobacter pylori resistance to clarithromycin in northeast China. | 2004 | World J. Gastroenterol. | pmid:15052698 |
| Sargýn M et al. | Type 2 diabetes mellitus affects eradication rate of Helicobacter pylori. | 2003 | World J. Gastroenterol. | pmid:12717872 |
| Lai YC et al. | Pre-treatment urea breath test results predict the efficacy of Helicobacter pylori eradication therapy in patients with active duodenal ulcers. | 2004 | World J. Gastroenterol. | pmid:15052680 |
| Cianci R et al. | Third-line rescue therapy for Helicobacter pylori infection. | 2006 | World J. Gastroenterol. | pmid:16688818 |
| Zhang L et al. | Eradication of H pylori infection in a rural population: one-day quadruple therapy versus 7-day triple therapy. | 2006 | World J. Gastroenterol. | pmid:16804982 |
| Chang CC et al. | Anti-Helicobacter pylori therapy significantly reduces Helicobacter pylori -induced gastric mucosal damage in Mongolian gerbils. | 2005 | World J. Gastroenterol. | pmid:15742400 |
| Feng LY et al. | Effects of killing Helicobacter pylori quadruple therapy on peptic ulcer: a randomized double-blind clinical trial. | 2005 | World J. Gastroenterol. | pmid:15742421 |
| Zhou Q et al. | Drug utilization of clarithromycin for gastrointestinal disease treatment. | 2008 | World J. Gastroenterol. | pmid:18932287 |
| Shimbo I et al. | Effect of Clostridium butyricum on fecal flora in Helicobacter pylori eradication therapy. | 2005 | World J. Gastroenterol. | pmid:16437727 |
| Sugimoto M and Furuta T | Efficacy of tailored Helicobacter pylori eradication therapy based on antibiotic susceptibility and CYP2C19 genotype. | 2014 | World J. Gastroenterol. | pmid:24914361 |
| Heo J and Jeon SW | Optimal treatment strategy for Helicobacter pylori: era of antibiotic resistance. | 2014 | World J. Gastroenterol. | pmid:24914324 |
| Bustamante-Rengifo JA et al. | Effect of treatment failure on the CagA EPIYA motif in strains from Colombian subjects. | 2017 | World J. Gastroenterol. | pmid:28373764 |
| Chen KY et al. | Hybrid vs sequential therapy for eradication of Helicobacter pylori in Taiwan: A prospective randomized trial. | 2015 | World J. Gastroenterol. | pmid:26420970 |
| Hwang JJ et al. | Efficacy of moxifloxacin-based sequential and hybrid therapy for first-line Helicobacter pylori eradication. | 2015 | World J. Gastroenterol. | pmid:26401089 |
| Mohammadi M et al. | Helicobacter pylori antibiotic resistance in Iran. | 2005 | World J. Gastroenterol. | pmid:16273615 |
| Wu JY et al. | Detection of genotypic clarithromycin-resistant Helicobacter pylori by string tests. | 2014 | World J. Gastroenterol. | pmid:24695835 |
| Garza-González E et al. | A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication. | 2014 | World J. Gastroenterol. | pmid:24587620 |
| Farshad S et al. | Antimicrobial susceptibility of Helicobacter pylori strains isolated from patients in Shiraz, Southern Iran. | 2010 | World J. Gastroenterol. | pmid:21128326 |
| Salimi A et al. | Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. | 2016 | Xenobiotica | pmid:26068526 |
| Pan W et al. | Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. | 2013 | Xenobiotica | pmid:22830954 |
| Kanayama N et al. | Drug-drug interactions in the metabolism of imidafenacin: role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes. | 2007 | Xenobiotica | pmid:17484517 |
| Burt HJ et al. | IC50-based approaches as an alternative method for assessment of time-dependent inhibition of CYP3A4. | 2010 | Xenobiotica | pmid:20230210 |
| Kubo JI et al. | Pharmacokinetic evaluation of high pulmonary disposition of clarithromycin after systemic administration. | 2002 | Xenobiotica | pmid:12419017 |
| Yamamoto T et al. | Prediction of oral clearance from in vitro metabolic data using recombinant CYPs: comparison among well-stirred, parallel-tube, distributed and dispersion models. | 2005 | Xenobiotica | pmid:16192112 |
| Niioka T | Clinical usefulness of limited sampling strategies for estimating AUC of proton pump inhibitors. | 2011 | Yakugaku Zasshi | pmid:21372537 |
| Suzuki A et al. | [Clinical efficacy of kanamycin for Mycobacterium avium complex disease]. | 2008 | Yakugaku Zasshi | pmid:18311066 |
| Matsuo R et al. | [Bitterness of the mixture of clarithromycin dry syrup and carbocisteine preparation--difference between brand name and generic drugs]. | 2008 | Yakugaku Zasshi | pmid:18311069 |
| Omura S et al. | [Research and development of clarithromycin]. | 1992 | Yakugaku Zasshi | pmid:1469609 |
| Vakil N | Treatment of H. pylori infection: the reality. | 1998 Mar-Apr | Yale J Biol Med | pmid:10378357 |
| Wang J et al. | [Different concentrations of clarithromycin ophthalmic gel for rabbits corneal ulcers induced by Staphylococcus aureus]. | 2008 | Yan Ke Xue Bao | pmid:18709951 |
| Qin LH and Tang X | [Preparation and evaluation of clarithromycin emulsion for injection]. | 2006 | Yao Xue Xue Bao | pmid:17184111 |
| Zhang T et al. | [Preparation and evaluation of enteric-coated and taste masking clarithromycin granules]. | 2011 | Yao Xue Xue Bao | pmid:22375429 |
| Ma HL et al. | [Polarographic catalytic wave of clarithromycin and its applications]. | 2004 | Yao Xue Xue Bao | pmid:15700824 |
| Lee SH et al. | Sequential bilateral lung resection in a patient with Mycobacterium abscessus lung disease refractory to medical treatment. | 2010 | Yonsei Med. J. | pmid:20046529 |
| Jun HJ et al. | Successful treatment of Mycobacterium celatum pulmonary disease in an immunocompetent patient using antimicobacterial chemotherapy and combined pulmonary resection. | 2010 | Yonsei Med. J. | pmid:20879072 |
| Chang JH et al. | A case of acute hepatitis with Mycoplasma pneumoniae infection and transient depression of multiple coagulation factors. | 2008 | Yonsei Med. J. | pmid:19108034 |
| Koh H et al. | Nodular gastritis and pathologic findings in children and young adults with Helicobacter pylori infection. | 2007 | Yonsei Med. J. | pmid:17461522 |
| Tsai SH et al. | Hypoglycemia revisited in the acute care setting. | 2011 | Yonsei Med. J. | pmid:22028152 |
| Kwon YS et al. | Solitary pulmonary nodule due to Mycobacterium intracellulare: the first case in Korea. | 2007 | Yonsei Med. J. | pmid:17326256 |
| Park HK et al. | Clinical characteristics and treatment outcomes of Mycobacterium kansasii lung disease in Korea. | 2010 | Yonsei Med. J. | pmid:20499421 |
| Hatipoglu ON and Tasan Y | A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. | 2000 | Yonsei Med. J. | pmid:10957888 |
| Sim YS et al. | Standardized combination antibiotic treatment of Mycobacterium avium complex lung disease. | 2010 | Yonsei Med. J. | pmid:20879056 |
| Jeen YT et al. | Differentiation between reinfection and recrudescence of helicobacter pylori strains using PCR-based restriction fragment length polymorphism analysis. | 2001 | Yonsei Med. J. | pmid:11293500 |
| Lee KY et al. | Two cases of acute leukopenia induced by colchicine with concurrent immunosuppressants use in Behçet's disease. | 2008 | Yonsei Med. J. | pmid:18306487 |
| Chin BS et al. | The characteristics of metallo-β-lactamase-producing gram-negative bacilli isolated from sputum and urine: a single center experience in Korea. | 2011 | Yonsei Med. J. | pmid:21319358 |
| Park HY et al. | Pulmonary disease caused by Mycobacterium xenopi: the first case in Korea. | 2007 | Yonsei Med. J. | pmid:17963348 |
| Knippig C et al. | Prevalence of H. pylori-infection in family members of H. pylori positive and its influence on the reinfection rate after successful eradication therapy: a two-year follow-up. | 2002 | Z Gastroenterol | pmid:12055660 |
| Lüth S et al. | 4-day triple therapy with rabeprazole, amoxicillin and clarithromycin in the eradication of Helicobacter pylori in patients with peptic ulcer disease--A pilot study. | 2001 | Z Gastroenterol | pmid:11367976 |
| Fritzsch J et al. | [Eosinophilic gastritis after helicobacter pylori eradication]. | 2008 | Z Gastroenterol | pmid:19053006 |
| Bayerdörffer E | [The MACH2 Study: value of inhibiting gastric acid secretion in eradication of Helicobacter pylori with a one week triple therapy protocol]. | 2000 | Z Gastroenterol | pmid:10689750 |
| Schepp W | [Omeprazole + clarithromycin + metronidazole--a new standard for eradication of Helicobacter pylori]. | 1995 | Z Gastroenterol | pmid:7502558 |
| Regnath T et al. | [Real-time PCR assay for rapid detection of clarithromycin-resistant helicobacter pylori in gastric biopsy specimens]. | 2004 | Z Gastroenterol | pmid:15592960 |
| Stolte M et al. | Cure of autoimmune gastritis by Helicobacter pylori eradication in a 21-year-old male. | 1998 | Z Gastroenterol | pmid:9773482 |
| Labenz J and Stolte M | [Is lack of stomach carcinoma prevention by Helicobacter pylori eradication unethical?]. | 1999 | Z Gastroenterol | pmid:10458014 |
| Schilling D et al. | [Eradication of helicobacter pylori: symptomatic treatment of reflux disease?]. | 2002 | Z Gastroenterol | pmid:12122605 |
| Krasz S et al. | [Current value of quinolones in Helicobacter pylori therapy]. | 2011 | Z Gastroenterol | pmid:21811951 |
| Bojarski C et al. | Patients with dyspepsia benefit from eradication of Helicobacter pylori if other organic causes for dyspepsia were carefully ruled out. | 2000 | Z Gastroenterol | pmid:10768243 |
| Schütze K and Hentschel E | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. | 1995 | Z Gastroenterol | pmid:8600661 |
| Tillenburg B et al. | [Helicobacter pylori: pretherapeutic resistance status in Germany (Ruhr area)]. | 1997 | Z Gastroenterol | pmid:9173687 |
| Hellmeyer L et al. | [Q Fever in pregnancy: a case report and review of the literature]. | 2002 Sep-Oct | Z Geburtshilfe Neonatol | pmid:12395293 |
| Knothe H | [Short-term therapy of acute respiratory and ORL infections with Clarithromycin]. | 1992 | Z Gesamte Inn Med | pmid:9022402 |
| Alter P et al. | [Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis]. | 2000 | Z Kardiol | pmid:11013974 |
| Fabry W et al. | Comparison of the E test and a proportion dilution method for susceptibility testing of Mycobacterium tuberculosis. | 1995 | Zentralbl. Bakteriol. | pmid:9810662 |
| Gamova NA | [Drug sensitivity of Ureaplasma urealyticum, persisting in patients with chronic inflammatory diseases of the urogenital tract]. | 2003 Jul-Aug | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:12966887 |
| Wang F et al. | [Five-day rabeprazole-based triple therapy for helicobacter pylori infection]. | 2004 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:16137055 |
| Li Y et al. | [Efficacy of 4 kinds of triple strategy for Helicobacter pylori eradication]. | 2008 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:19141980 |
| Wu S et al. | [Anti-Helicobacter pylori treatment in patients with idiopathic thrombocytopenic purpura]. | 2009 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:20045922 |
| Wang F et al. | [Antibiotic resistance of Helicobacter pylori]. | 2007 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:17611323 |
| Li F et al. | [Effect of prokinetic agents on the electrical activity of stomach and duodenum in rats]. | 2009 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:19648670 |
| Tang D et al. | [Efficacy of bismuth containing quadruple therapies on Helicobacter pylori eradication in patients with history of antibiotic treatment]. | 2018 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:30124214 |
| Tu S and Yang H | [Progress in the treatment of Helicobacter pylori infection]. | 2014 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:25269503 |
| Zhao HM et al. | [Clinical effect of triple therapy combined with Saccharomyces boulardii in the treatment of Helicobacter pylori infection in children]. | 2014 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:24661511 |
| Huang LP et al. | [Antimicrobial resistance of 36 strains of Helicobacter pylori in adolescents]. | 2009 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:19292962 |
| Xiang L et al. | [Different courses of esomeprazole-based triple therapy for Helicobactor pylori infection in children]. | 2007 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:17582255 |
| Yang CS et al. | [Study of correlation between Helicobacter pylori infection and hyperammonemia and hepatic encephalopathy in cirrhotic patients]. | 2007 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:17631712 |
| Guo SB et al. | [Preparation and identification of the oligonucleotide chip for detecting the virulence-associated genotypes and drug resistance of Helicobacter pylori]. | 2007 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:17380677 |
| Luo Q et al. | [Clinical effect of clarithromycin therapy in patients with chronic rhinosinusitis]. | 2014 | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:24742507 |
| Yan WH et al. | [Rapid detection of clarithromycin resistant Helicobacter pylori from children's gastric biopsy specimens by polymerase chain reaction-restriction fragment length polymorphism]. | 2009 | Zhonghua Er Ke Za Zhi | pmid:20078998 |
| Yan WH et al. | [Preliminary study on in-vitro induction of antibiotic resistance in Helicobacter pylori strains isolated from children]. | 2007 | Zhonghua Er Ke Za Zhi | pmid:18021568 |
| Hua CZ et al. | [Serotypes and antibiotics-resistance patterns of 247 strains of Haemophilus Influenzae isolated from children in Hangzhou]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:15631716 |
| Chen J et al. | [Prevalence of Helicobacter pylori resistant to clarithromycin, amoxicillin and metronidazole in children]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:16221349 |
| Huang J et al. | [A 10-day sequential therapy for eradication of Helicobacter pylori infection in children]. | 2012 | Zhonghua Er Ke Za Zhi | pmid:23158730 |
| Yang H et al. | [Macrolide-resistant Streptococcus pneumoniae in the pediatric population in Beijing]. | 2004 | Zhonghua Er Ke Za Zhi | pmid:15733368 |