| MeSH term | MeSH ID | Detail |
|---|---|---|
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Sacroiliitis | D058566 | 1 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Upper Extremity Deep Vein Thrombosis | D056824 | 1 associated lipids |
| Leprosy, Paucibacillary | D056005 | 2 associated lipids |
| Extensively Drug-Resistant Tuberculosis | D054908 | 1 associated lipids |
| Buruli Ulcer | D054312 | 1 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Renal Insufficiency | D051437 | 8 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Matsumoto T et al. | Regression of mucosa-associated lymphoid-tissue lymphoma of rectum after eradication of Helicobacter pylori. | 1997 | Lancet | pmid:9228971 |
| DÃaz F et al. | [Cat-scratch disease. A report of 4 cases and a review of the literature]. | 1997 | Rev Clin Esp | pmid:9102668 |
| Horgen L et al. | Postantibiotic effect of amikacin, rifampin, sparfloxacin, clofazimine and clarithromycin against Mycobacterium avium. | 1997 | Res. Microbiol. | pmid:9765852 |
| Axon AT et al. | Ranitidine bismuth citrate and clarithromycin twice daily in the eradication of Helicobacter pylori. | 1997 | Aliment. Pharmacol. Ther. | pmid:9042977 |
| Gotoh A et al. | Interaction of drugs for eradication therapy against antibiotic-resistant strains of Helicobacter pylori. | 1997 | Microbiol. Immunol. | pmid:9444328 |
| Labenz J et al. | One-week low-dose triple therapy for Helicobacter pylori is sufficient for relief from symptoms and healing of duodenal ulcers. | 1997 | Aliment. Pharmacol. Ther. | pmid:9042978 |
| Labenz J et al. | Efficacy and tolerability of a one-week triple therapy consisting of pantoprazole, clarithromycin and amoxycillin for cure of Helicobacter pylori infection in patients with duodenal ulcer. | 1997 | Aliment. Pharmacol. Ther. | pmid:9042979 |
| Goh KL et al. | Comparison of two 1-week low-dose omeprazole triple therapies--optimal treatment for Helicobacter pylori infection? | 1997 | Aliment. Pharmacol. Ther. | pmid:9663838 |
| Buckley MJ et al. | Metronidazole resistance reduces efficacy of triple therapy and leads to secondary clarithromycin resistance. | 1997 | Dig. Dis. Sci. | pmid:9365144 |
| Misiewicz JJ et al. | One week triple therapy for Helicobacter pylori: a multicentre comparative study. Lansoprazole Helicobacter Study Group. | 1997 | Gut | pmid:9462204 |
| Loo VG et al. | In-vitro susceptibility of Helicobacter pylori to ampicillin, clarithromycin, metronidazole and omeprazole. | 1997 | J. Antimicrob. Chemother. | pmid:9462442 |
| Hotz J | [Reflux disease of the gastrointestinal tract. Acute therapy and long-term care in daily practice. 2. Therapeutic procedure--diagnosis--therapy-diagram]. | 1997 | Fortschr. Med. | pmid:9480263 |
| Klein JO | History of macrolide use in pediatrics. | 1997 | Pediatr. Infect. Dis. J. | pmid:9109154 |
| Kato A | [Effect of erythromycin and clarithromycin on ion transport across dissected canine tracheal epithelium]. | 1997 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9103848 |
| Meyer JM et al. | In vitro synergy testing of clarithromycin and 14-hydroxyclarithromycin with amoxicillin or bismuth subsalicylate against Helicobacter pylori. | 1997 | Antimicrob. Agents Chemother. | pmid:9210696 |
| Chimura T | [Measurement of antibody titers to chlamydial infection and effects of levofloxacin in cystic cervicitis and chlamydial infection]. | 1997 | Jpn J Antibiot | pmid:9212369 |
| Phull PS et al. | Lansoprazole plus clarithromycin: evaluation of a new dual therapy for Helicobacter pylori eradication. | 1996 Oct-Nov | Br J Clin Pract | pmid:9015906 |
| Peeling RW and Brunham RC | Chlamydiae as pathogens: new species and new issues. | 1996 Oct-Dec | Emerging Infect. Dis. | pmid:8969247 |
| Prescott LM | Clarithromycin for MAC prevention offers additional benefits. | 1996 May-Jun | Posit Aware | pmid:11363431 |
| Mertl SL | The role of clarithromycin in the prophylaxis of disseminated Mycobacterium avium-intracellulare infection in patients with AIDS. | 1996 May-Jun | Pharmacotherapy | pmid:8726597 |
| Ono T et al. | In vitro and in vivo antibacterial activities of clarithromycin. | 1996 May-Jun | Chemotherapy | pmid:8983882 |
| Nightingale SL | From the Food and Drug Administration. | 1996 May 22-29 | JAMA | pmid:8622234 |
| Sketris IS et al. | Possible role of the intestinal P-450 enzyme system in a cyclosporine-clarithromycin interaction. | 1996 Mar-Apr | Pharmacotherapy | pmid:8820476 |
| Akamatsu H et al. | Enhanced effect of clarithromycin on neutrophil function in vitro. | 1996 Mar-Apr | J. Int. Med. Res. | pmid:8737228 |
| Papp J et al. | Efficacy of nizatidine, clarithromycin and bismuth subcitrate therapy for Helicobacter pylori eradication in duodenal ulcer patients--a preliminary report. | 1996 Jul-Aug | Br J Clin Pract | pmid:8794601 |
| Tursi A et al. | One-week low-dose triple therapy vs. two-week medium-dose double therapy for H.pylori infection. | 1996 Jul-Aug | Hepatogastroenterology | pmid:8884304 |
| Amsden GW | Erythromycin, clarithromycin, and azithromycin: are the differences real? | 1996 Jan-Feb | Clin Ther | pmid:8851453 |
| Sander P et al. | Ribosomal drug resistance in mycobacteria. | 1996 Jan-Feb | Res. Microbiol. | pmid:8761724 |
| Shafran SD et al. | A comparison of two regimens for the treatment of Mycobacterium avium complex bacteremia in AIDS: rifabutin, ethambutol, and clarithromycin versus rifampin, ethambutol, clofazimine, and ciprofloxacin. Canadian HIV Trials Network Protocol 010 Study Group. | 1996 | N. Engl. J. Med. | pmid:8676931 |
| Shimoyama T et al. | Validity of various diagnostic tests to evaluate cure of Helicobacter pylori infection. | 1996 | J. Gastroenterol. | pmid:8680535 |
| MacConnachie AM | Clarithromycin (klaricid, Abbott). | 1996 | Intensive Crit Care Nurs | pmid:8696027 |
| Meier A et al. | Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population. | 1996 | J. Infect. Dis. | pmid:8699066 |
| O'Hara K and Yamamoto K | Reaction of roxithromycin and clarithromycin with macrolide-inactivating enzymes from highly erythromycin-resistant Escherichia coli. | 1996 | Antimicrob. Agents Chemother. | pmid:8849224 |
| Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
| Vermot D et al. | Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. | 1996 | Antimicrob. Agents Chemother. | pmid:8851620 |
| van der Hulst RW et al. | Therapeutic options after failed Helicobacter pylori eradication therapy. | 1996 | Am. J. Gastroenterol. | pmid:8931413 |
| Alder JD et al. | Relevance of the ferret model of Helicobacter-induced gastritis to evaluation of antibacterial therapies. | 1996 | Am. J. Gastroenterol. | pmid:8931416 |
| Koeck JL et al. | Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment. | 1996 | Clin. Infect. Dis. | pmid:8909856 |
| Hunt RH | Eradication of Helicobacter pylori infection. | 1996 | Am. J. Med. | pmid:8644782 |
| Dhaenens L et al. | In-vitro activities of clarithromycin and other antimicrobial agents against Helicobacter pylori isolated from children. | 1996 | J. Antimicrob. Chemother. | pmid:8877551 |
| Tursi A et al. | Helicobacter pylori eradication helps resolve pyloric and duodenal stenosis. | 1996 | J. Clin. Gastroenterol. | pmid:8877648 |
| Thor P et al. | Dysfunction in gastric myoelectric and motor activity in Helicobacter pylori positive gastritis patients with non-ulcer dyspesia. | 1996 | J. Physiol. Pharmacol. | pmid:8877902 |
| Ji B et al. | Bactericidal activity of single dose of clarithromycin plus minocycline, with or without ofloxacin, against Mycobacterium leprae in patients. | 1996 | Antimicrob. Agents Chemother. | pmid:8878595 |
| Ji B et al. | Bactericidal activities of combinations of new drugs against Mycobacterium leprae in nude mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834886 |
| Yamamoto T et al. | Activity of KRM-1648 alone or in combination with both ethambutol and kanamycin or clarithromycin against Mycobacterium intracellulare infections in beige mice. | 1996 | Antimicrob. Agents Chemother. | pmid:8834892 |
| Ji B et al. | How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice? | 1996 | Antimicrob. Agents Chemother. | pmid:8834894 |
| Dattwyler RJ et al. | Clarithromycin in treatment of early Lyme disease: a pilot study. | 1996 | Antimicrob. Agents Chemother. | pmid:8834900 |
| Jaup BK | Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin, and clarithromycin. | 1996 | Helicobacter | pmid:9398878 |
| Moayyedi P et al. | Comparison of one or two weeks of lansoprazole, amoxicillin, and clarithromycin in the treatment of Helicobacter pylori. | 1996 | Helicobacter | pmid:9398880 |
| Mégraud F and Malfertheiner P | Treatment of Helicobacter pylori infection: summary of a meeting at the Fourth United European Gastroenterology Week, September 20, 1995. | 1996 | Helicobacter | pmid:9398889 |