| MeSH term | MeSH ID | Detail |
|---|---|---|
| Chlamydial Pneumonia | D061387 | 2 associated lipids |
| Sacroiliitis | D058566 | 1 associated lipids |
| Plaque, Atherosclerotic | D058226 | 7 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Upper Extremity Deep Vein Thrombosis | D056824 | 1 associated lipids |
| Leprosy, Paucibacillary | D056005 | 2 associated lipids |
| Extensively Drug-Resistant Tuberculosis | D054908 | 1 associated lipids |
| Buruli Ulcer | D054312 | 1 associated lipids |
| Immune Reconstitution Inflammatory Syndrome | D054019 | 1 associated lipids |
| Renal Insufficiency | D051437 | 8 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bates JH | Mycobacterium avium disease: progress at last. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665029 |
| Wallace RJ et al. | Clarithromycin regimens for pulmonary Mycobacterium avium complex. The first 50 patients. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665032 |
| Frothingham R | Clarithromycin treatment for Mycobacterium avium-intracellulare complex lung disease. | 1996 | Am. J. Respir. Crit. Care Med. | pmid:8665069 |
| Treille S et al. | Kidney graft dysfunction after drug interaction between clarithromycin and cyclosporin. | 1996 | Nephrol. Dial. Transplant. | pmid:8672003 |
| Araki J et al. | [A case of Mounier-Kuhn syndrome]. | 1996 | Nippon Naika Gakkai Zasshi | pmid:8708483 |
| Lowe SH et al. | Uveitis during treatment of disseminated Mycobacterium avium-intracellulare complex infection with the combination of rifabutin, clarithromycin and ethambutol. | 1996 | Neth J Med | pmid:8710040 |
| Vasquez A et al. | Metronidazole and clarithromycin resistance in Helicobacter pylori determined by measuring MICs of antimicrobial agents in color indicator egg yolk agar in a miniwell format. The Gastrointestinal Physiology Working Group of Universidad Peruana Cayetano Heredia and the Johns Hopkins University. | 1996 | J. Clin. Microbiol. | pmid:8727909 |
| Darouiche RO et al. | Recurrent disseminated infection with Mycobacterium avium complex identified in tissues by molecular analysis. | 1996 | Clin. Infect. Dis. | pmid:8729215 |
| Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
| Hultén K et al. | New pharmacokinetic in vitro model for studies of antibiotic activity against intracellular microorganisms. | 1996 | Antimicrob. Agents Chemother. | pmid:9124830 |
| Xu G et al. | Effect of macrolide antibiotics on macrophage functions. | 1996 | Microbiol. Immunol. | pmid:8865152 |
| van der Hulst RW et al. | Therapeutic options after failed Helicobacter pylori eradication therapy. | 1996 | Am. J. Gastroenterol. | pmid:8931413 |
| Alder JD et al. | Relevance of the ferret model of Helicobacter-induced gastritis to evaluation of antibacterial therapies. | 1996 | Am. J. Gastroenterol. | pmid:8931416 |
| Young LS | Treatment and prophylaxis of Mycobacterium avium complex. | 1996 | Int J STD AIDS | pmid:8652724 |
| Vilmà nyi E et al. | Clarithromycin pharmacokinetics after oral administration with or without fasting in crossbred beagles. | 1996 | J Small Anim Pract | pmid:8934426 |
| Yago K et al. | [Protein binding of clarithromycin in patients with chronic renal failure]. | 1996 | Jpn J Antibiot | pmid:8935121 |
| McCutchan JA | Azithromycin in the prophylaxis of opportunistic infections in AIDS. | 1996 | Int J STD AIDS | pmid:8652726 |
| Koguchi M et al. | [Antimicrobial activities of clarithromycin against clinical isolates]. | 1996 | Jpn J Antibiot | pmid:8935125 |
| Tomioka H et al. | [Preclinical study of therapeutic agents used against Mycobacterium avium complex infections--with special reference to new macrolides and new quinolones]. | 1996 | Kekkaku | pmid:8999135 |
| Tsuyuguchi K | [In vitro anti-MAC activities of new quinolones in focus (1)]. | 1996 | Kekkaku | pmid:8999136 |
| Sakatani M | [Pilot studies on the treatment of Mycobacterium avium complex lung disease--new macrolides and new quinolones. (1) Continuous positive cases (failure of the initial chemotherapy)]. | 1996 | Kekkaku | pmid:8999139 |
| Tanaka E | [Pilot studies on the treatment of Mycobacterium avium complex lung disease--new macrolides and new quinolones. (2) Multi-drug chemotherapy for initial cases on trial]. | 1996 | Kekkaku | pmid:8999140 |
| Koeck JL et al. | Disseminated Mycobacterium simiae infection in a patient with AIDS: clinical features and treatment. | 1996 | Clin. Infect. Dis. | pmid:8909856 |
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| Hackelsberger A and Malfertheiner P | A risk-benefit assessment of drugs used in the eradication of Helicobacter pylori infection. | 1996 | Drug Saf | pmid:8862962 |
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| Cone LA et al. | Mania due to clarithromycin therapy in a patient who was not infected with human immunodeficiency virus. | 1996 | Clin. Infect. Dis. | pmid:8853002 |
| Yousfi MM et al. | One-week triple therapy with omeprazole, amoxycillin and clarithromycin for treatment of Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8853767 |
| Schimkat M et al. | Rifabutin-associated anterior uveitis in patients infected with human immunodeficiency virus. | 1996 | Ger J Ophthalmol | pmid:8854102 |
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| Stone GG et al. | Identification of a 23S rRNA gene mutation in clarithromycin-resistant Helicobacter pylori. | 1996 | Helicobacter | pmid:9432314 |
| Sjöström JE and Larsson H | Factors affecting growth and antibiotic susceptibility of Helicobacter pylori: effect of pH and urea on the survival of a wild-type strain and a urease-deficient mutant. | 1996 | J. Med. Microbiol. | pmid:8636959 |
| Cammarota G et al. | Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971300 |
| Clarithromycin and omeprazole for Helicobacter pylori. | 1996 | Med Lett Drugs Ther | pmid:8637481 | |
| Pilotto A et al. | Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971305 |
| Asnis DS et al. | Mycobacterium avium-intracellulare complex pneumonia in a non-HIV-infected individual: an increasingly recognized disease. | 1996 | South. Med. J. | pmid:8638183 |
| Adachi T et al. | Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. | 1996 | J. Allergy Clin. Immunol. | pmid:8977529 |
| Labenz J et al. | [Ulcer healing through the elimination of Helicobacter pylori: is a week of therapy enough?]. | 1996 | Dtsch. Med. Wochenschr. | pmid:8565802 |
| Goh KL et al. | Helicobacter pylori eradication with short-term therapy leads to duodenal ulcer healing without the need for continued acid suppression therapy. | 1996 | Eur J Gastroenterol Hepatol | pmid:8804868 |
| Berger C et al. | Treatment of nontuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin. | 1996 | J. Pediatr. | pmid:8774511 |
| Sito E et al. | One week treatment with omeprazole, clarithromycin and tinidazole or lansoprazole, amoxicillin and metronidazole for cure of Helicobacter pylori infection in duodenal ulcer patients. | 1996 | J. Physiol. Pharmacol. | pmid:8777303 |
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| Plemmons RM et al. | Otitis media and mastoiditis due to Mycobacterium fortuitum: case report, review of four cases, and a cautionary note. | 1996 | Clin. Infect. Dis. | pmid:8783722 |
| Bagarazzi ML et al. | Pulmonary Mycobacterium gordonae infection in a two-year-old child: case report. | 1996 | Clin. Infect. Dis. | pmid:8783736 |
| Flamm RK et al. | Kill kinetics of antimicrobial agents against Helicobacter pylori. | 1996 | J. Antimicrob. Chemother. | pmid:8937967 |
| Bermudez LE et al. | Effect of ethambutol on emergence of clarithromycin-resistant Mycobacterium avium complex in the beige mouse model. | 1996 | J. Infect. Dis. | pmid:8940212 |
| Nagashima R et al. | Regression of duodenal mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori. | 1996 | Gastroenterology | pmid:8942749 |
| Ferguson PJ and Saulsbury FT | Successful treatment of chronic Mycobacterium abscessus otitis media with clarithromycin. | 1996 | Pediatr. Infect. Dis. J. | pmid:8866816 |
| Giacometti A et al. | In-vitro activity of macrolides alone and in combination with artemisin, atovaquone, dapsone, minocycline or pyrimethamine against Cryptosporidium parvum. | 1996 | J. Antimicrob. Chemother. | pmid:8889715 |
| Tracy TS and Johns M | Comment: delirium probably induced by clarithromycin in a patient receiving fluoxetine. | 1996 | Ann Pharmacother | pmid:8893135 |
| Ghebremichael S et al. | Antimycobacterial synergism of clarithromycin and rifabutin. | 1996 | Scand. J. Infect. Dis. | pmid:8893404 |
| Yousfi MM et al. | Metronidazole, ranitidine and clarithromycin combination for treatment of Helicobacter pylori infection (modified Bazzoli's triple therapy). | 1996 | Aliment. Pharmacol. Ther. | pmid:8871452 |
| Fisher M et al. | The management of mycobacterial infections in HIV seropositive individuals. Jefferiss Wing Therapeutics and Protocols Group. | 1996 | Int J STD AIDS | pmid:8876354 |
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| Delchier JC et al. | Omeprazole-amoxycillin versus omeprazole-amoxycillin-clarithromycin in the eradication of Helicobacter pylori. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791948 |
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| Weldon MJ et al. | A seven-day Helicobacter pylori treatment regimen using clarithromycin, omeprazole and tripotassium dicitrato bismuthate. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791951 |
| Tursi A et al. | Low-dose omeprazole plus clarithromycin and either tinidazole or amoxycillin for Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791952 |
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| Welsh L et al. | In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8787907 |
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| NIAID study rules out high-dose clarithromycin for AIDS-related MAC. | 1996 | AIDS Patient Care STDS | pmid:11361534 | |
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| New data suggest antibiotic clarithromycin is effective in prolonging life of AIDS patients. | 1996 | AIDS Patient Care STDS | pmid:11361575 | |
| Clarithromycin and MAC. | 1996 | AIDS Patient Care STDS | pmid:11361673 | |
| Harris AW et al. | Lansoprazole, clarithromycin and metronidazole for seven days in Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971302 |
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| Abbott files SNDA for MAC prophylaxis. | 1995 | J Int Assoc Physicians AIDS Care | pmid:11362606 | |
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