clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Araujo FG et al. Activity of clarithromycin alone or in combination with other drugs for treatment of murine toxoplasmosis. 1992 Antimicrob. Agents Chemother. pmid:1489188
Gan VN et al. Pharmacokinetics of a clarithromycin suspension in infants and children. 1992 Antimicrob. Agents Chemother. pmid:1489191
Denny FW Current management of streptococcal pharyngitis. 1992 J Fam Pract pmid:1453145
Schrock CG Clarithromycin vs penicillin in the treatment of streptococcal pharyngitis. 1992 J Fam Pract pmid:1453146
Chaisson R Clarithromycin is effective against M. avium complex in AIDS. 1992 Am Fam Physician pmid:1456199
Ji B et al. Selection of resistant mutants of Mycobacterium avium in beige mice by clarithromycin monotherapy. 1992 Antimicrob. Agents Chemother. pmid:1482155
Rastogi N and Goh KS Effect of pH on radiometric MICs of clarithromycin against 18 species of mycobacteria. 1992 Antimicrob. Agents Chemother. pmid:1482156
Rastogi N et al. Activity of clarithromycin compared with those of other drugs against Mycobacterium paratuberculosis and further enhancement of its extracellular and intracellular activities by ethambutol. 1992 Antimicrob. Agents Chemother. pmid:1482157
Derouin F et al. Synergistic activity of clarithromycin and minocycline in an animal model of acute experimental toxoplasmosis. 1992 Antimicrob. Agents Chemother. pmid:1482160
Chapelsky MC et al. Renal tubular enzyme effects of clarithromycin in comparison with gentamicin and placebo in volunteers. 1992 Jul-Aug Drug Saf pmid:1355971
Hoover WW et al. Clarithromycin in vitro activity enhanced by its major metabolite, 14-hydroxyclarithromycin. 1992 Mar-Apr Diagn. Microbiol. Infect. Dis. pmid:1533827
de Campora E et al. Comparative efficacy and safety of roxithromycin and clarithromycin in upper respiratory tract infections. 1992 May-Jun Diagn. Microbiol. Infect. Dis. pmid:1535578
Nilsen OG et al. Macrolide pharmacokinetics and dose scheduling of roxithromycin. 1992 May-Jun Diagn. Microbiol. Infect. Dis. pmid:1535579
Friend DR Polyacrylate resin microcapsules for taste masking of antibiotics. 1992 Oct-Dec J Microencapsul pmid:1403495
Ruf B et al. Effectiveness of the macrolide clarithromycin in the treatment of Mycobacterium avium complex infection in HIV-infected patients. 1992 Sep-Oct Infection pmid:1428183
Humphreys JE et al. A clarithromycin sensitivity survey in the United Kingdom using Stokes' method. 1993 J. Antimicrob. Chemother. pmid:8226438
Scaglione F et al. Immunostimulation by clarithromycin in healthy volunteers and chronic bronchitis patients. 1993 J Chemother pmid:8229150
MacGowan AR et al. Synergy testing of macrolide combinations using the chequerboard technique. 1993 J. Antimicrob. Chemother. pmid:8144439
Ximenes E et al. [Ciprofloxacin, clarithromycin, rifampin: in vitro bactericidal activity of double and triple drug combinations against strains of atypical mycobacteria]. 1993 Pathol. Biol. pmid:8233629
Peterson WL et al. Clarithromycin as monotherapy for eradication of Helicobacter pylori: a randomized, double-blind trial. 1993 Am. J. Gastroenterol. pmid:8237933