clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Saadat A et al. | The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler. | 2014 | J. Pharm. Pharmacol. | pmid:24329164 |
| Rajput P et al. | Bifunctional capsular dosage form: novel fanicular cylindrical gastroretentive system of clarithromycin and immediate release granules of ranitidine HCl for simultaneous delivery. | 2014 | Int J Pharm | pmid:24309435 |
| Katayama M et al. | Preliminary study of effects of multiple oral dosing of clarithromycin on the pharmacokinetics of cyclosporine in dogs. | 2014 | J. Vet. Med. Sci. | pmid:24189617 |
| Papastergiou V et al. | Current and future insights in H. pylori eradication regimens: the need of tailoring therapy. | 2014 | Curr. Pharm. Des. | pmid:24180408 |
| Tan X and Song Z | Human saliva-based quantitative monitoring of clarithromycin by flow injection chemiluminescence analysis: a pharmacokinetic study. | 2014 | Appl. Biochem. Biotechnol. | pmid:24166104 |
| Kakuda TN et al. | Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies. | 2014 | J. Antimicrob. Chemother. | pmid:24155058 |
| Seung KJ et al. | Salvage therapy for multidrug-resistant tuberculosis. | 2014 | Clin. Microbiol. Infect. | pmid:23991934 |
| Kathariya R et al. | Evaluation of subgingivally delivered 0.5% clarithromycin as an adjunct to nonsurgical mechanotherapy in the management of chronic periodontitis: a short-term double blinded randomized control trial. | 2014 | J Investig Clin Dent | pmid:23097216 |
| Bjerre M et al. | Osteoprotegerin independently predicts mortality in patients with stable coronary artery disease: the CLARICOR trial. | 2014 | Scand. J. Clin. Lab. Invest. | pmid:25026506 |
| Trotti LM et al. | Improvement in daytime sleepiness with clarithromycin in patients with GABA-related hypersomnia: Clinical experience. | 2014 | J. Psychopharmacol. (Oxford) | pmid:24306133 |
| Fowler J and Mahlen SD | Localized cutaneous infections in immunocompetent individuals due to rapidly growing mycobacteria. | 2014 | Arch. Pathol. Lab. Med. | pmid:25076301 |
| Ueda Y et al. | [Obstructive pneumonia and brain abscess due to Nocardia elegans in a patient with systemic lupus erythematosus]. | 2014 | Kansenshogaku Zasshi | pmid:24974451 |
| NegrÃn-González J et al. | Psychiatric adverse reaction induced by clarithromycin. | 2014 | Eur Ann Allergy Clin Immunol | pmid:24853570 |
| Kurosaki Y et al. | [Two cases of pulmonary Mycobacterium avium complex disease with resistance to clarithromycin]. | 2014 | Kekkaku | pmid:24979948 |
| Iwanaga K and Carter ER | Mycobacterium abscessus complex lung infection in a toddler with a tracheostomy. | 2014 | Pediatr. Pulmonol. | pmid:23460506 |
| Campanale M et al. | Nickel free-diet enhances the Helicobacter pylori eradication rate: a pilot study. | 2014 | Dig. Dis. Sci. | pmid:24595654 |
| Svanström H et al. | Use of clarithromycin and roxithromycin and risk of cardiac death: cohort study. | 2014 | BMJ | pmid:25139799 |
| Loreto ES et al. | New insights into the in vitro susceptibility of Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25223997 |
| Yamada K et al. | Azithromycin inhibits MUC5AC induction via multidrug-resistant Acinetobacter baumannii in human airway epithelial cells. | 2014 | Pulm Pharmacol Ther | pmid:24910464 |
| Ohe M and Hashino S | Successful treatment of primary immune thrombocytopenia in aged patients using clarithromycin. | 2014 | J. Formos. Med. Assoc. | pmid:24630039 |
| Zhou L et al. | A comparative study of sequential therapy and standard triple therapy for Helicobacter pylori infection: a randomized multicenter trial. | 2014 | Am. J. Gastroenterol. | pmid:24642580 |
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| Lee SH et al. | The drug resistance profile of Mycobacterium abscessus group strains from Korea. | 2014 | Ann Lab Med | pmid:24422193 |
| Pathak V et al. | Macrolide use leads to clinical and radiological improvement in patients with cryptogenic organizing pneumonia. | 2014 | Ann Am Thorac Soc | pmid:24460438 |
| Wu JY et al. | Evidence-based recommendations for successful Helicobacter pylori treatment. | 2014 | Expert Rev Gastroenterol Hepatol | pmid:24410470 |
| DÃaz Cuevas Z et al. | [Nodular skin lesions in a patient with rheumatoid arthritis under therapy with anti-tumor necrosis factor-α]. | 2014 | Med Clin (Barc) | pmid:23877097 |
| Jung YS et al. | [Trends in the eradication rates of Helicobacter pylori infection in Daegu and Gyeongsangbuk-do, Korea: multicenter study over 13 years]. | 2014 | Korean J Gastroenterol | pmid:24561694 |
| Vanderpas J et al. | Follow-up of Helicobacter pylori infection in children over two decades (1988-2007): persistence, relapse and acquisition rates. | 2014 | Epidemiol. Infect. | pmid:23809783 |
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| de Masson A et al. | Cavitary pulmonary disease in a patient treated with natalizumab. | 2014 | Presse Med | pmid:24742610 |
| Furuta T et al. | Sitafloxacin-based third-line rescue regimens for Helicobacter pylori infection in Japan. | 2014 | J. Gastroenterol. Hepatol. | pmid:24224808 |
| Page SR and Yee KC | Rhabdomyolysis in association with simvastatin and dosage increment in clarithromycin. | 2014 | Intern Med J | pmid:25041770 |
| Noguchi S et al. | Polymorphic transformation of antibiotic clarithromycin under acidic condition. | 2014 | J Pharm Sci | pmid:24375227 |
| Methaneethorn J et al. | A pharmacokinetic drug-drug interaction model of simvastatin and clarithromycin in humans. | 2014 | Conf Proc IEEE Eng Med Biol Soc | pmid:25571290 |
| Phillips RO et al. | Clinical and bacteriological efficacy of rifampin-streptomycin combination for two weeks followed by rifampin and clarithromycin for six weeks for treatment of Mycobacterium ulcerans disease. | 2014 | Antimicrob. Agents Chemother. | pmid:24323473 |
| McNicholl AG et al. | Randomised clinical trial comparing sequential and concomitant therapies for Helicobacter pylori eradication in routine clinical practice. | 2014 | Gut | pmid:23665990 |
| El-Garem Y et al. | Seminal Helicobacter pylori treatment improves sperm motility in infertile asthenozoospermic men. | 2014 | Urology | pmid:25432826 |
| Kim SY et al. | [Ten day concomitant therapy is superior to ten day sequential therapy for Helicobacter pylori eradication]. | 2014 | Korean J Gastroenterol | pmid:25420735 |
| Mustafa G and Necati B | Clarithromycin-associated rhabdomyolysis in an infant. | 2014 | J Clin Rheumatol | pmid:25417692 |
| Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
| Gui J et al. | [Subspecies identification for Mycobacterium abscessus group]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262692 |
| Ghrew MH et al. | Successful renal transplant in patient with controlled pulmonary non-tuberculous mycobacterium infection. | 2014 | Libyan J Med | pmid:25249307 |
| Yoon KH et al. | Clarithromycin-based standard triple therapy can still be effective for Helicobacter pylori eradication in some parts of the Korea. | 2014 | J. Korean Med. Sci. | pmid:25246742 |
| Matongo F and Nwodo UU | In vitro assessment of Helicobacter pylori ureases inhibition by honey fractions. | 2014 | Arch. Med. Res. | pmid:25240315 |
| Martos M et al. | Clarithromycin for first-line treatment of Helicobacter pylori infection after culture in high-resistance regions. | 2014 | Eur J Gastroenterol Hepatol | pmid:25229983 |
| Veraldi S et al. | Treatment of sporotrichoid fish tank granuloma with pulsed clarithromycin. | 2014 | Dermatology (Basel) | pmid:25228273 |
| Phillips RO et al. | Reply to "compliance with antimicrobial therapy for buruli ulcer". | 2014 | Antimicrob. Agents Chemother. | pmid:25225343 |
| Klis S et al. | Compliance with antimicrobial therapy for buruli ulcer. | 2014 | Antimicrob. Agents Chemother. | pmid:25225342 |
| Katayama M et al. | Preliminary study of interaction of clarithromycin with tacrolimus in cats. | 2014 | J. Vet. Med. Sci. | pmid:25099737 |
| Park CS et al. | Pretreatment antimicrobial susceptibility-guided vs. clarithromycin-based triple therapy for Helicobacter pylori eradication in a region with high rates of multiple drug resistance. | 2014 | Am. J. Gastroenterol. | pmid:25091062 |
| Cicek-Senturk G et al. | Acute mercury poisoning presenting as fever of unknown origin in an adult woman: a case report. | 2014 | J Med Case Rep | pmid:25084829 |
| Bilgin M et al. | Acute coronary syndrome secondary to clarithromycin: the first case and review of the literature. | 2014 | Turk Kardiyol Dern Ars | pmid:25080953 |
| Hsu PI et al. | Randomized controlled trial comparing 7-day triple, 10-day sequential, and 7-day concomitant therapies for Helicobacter pylori infection. | 2014 | Antimicrob. Agents Chemother. | pmid:25070099 |
| Patel SK et al. | Helicobacter pylori is not eradicated after triple therapy: a nested PCR based study. | 2014 | Biomed Res Int | pmid:25054141 |
| Elkhatib W and Noreddin A | Efficacy of ciprofloxacin-clarithromycin combination against drug-resistant Pseudomonas aeruginosa mature biofilm using in vitro experimental model. | 2014 | Microb. Drug Resist. | pmid:25050970 |
| Ohe M and Bohgaki T | Successful treatment with clarithromycin for patients with polymyalgia rheumatica. | 2014 | Korean J. Intern. Med. | pmid:25045305 |
| Martin JH and Coombes I | Mortality from common drug interactions systems, knowledge and clinical reasoning to optimise prescribing. | 2014 | Intern Med J | pmid:25041768 |
| Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
| Bonferoni MC et al. | Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid. | 2014 | Eur J Pharm Biopharm | pmid:24384070 |
| Philips RC et al. | Mycobacterium fortuitum infection arising in a new tattoo. | 2014 | Dermatol. Online J. | pmid:24945647 |
| Klesiewicz K et al. | PCR-RFLP detection of point mutations A2143G and A2142G in 23S rRNA gene conferring resistance to clarithromycin in Helicobacter pylori strains. | 2014 | Acta Biochim. Pol. | pmid:24927236 |
| Sugimoto M and Furuta T | Efficacy of tailored Helicobacter pylori eradication therapy based on antibiotic susceptibility and CYP2C19 genotype. | 2014 | World J. Gastroenterol. | pmid:24914361 |
| Heo J and Jeon SW | Optimal treatment strategy for Helicobacter pylori: era of antibiotic resistance. | 2014 | World J. Gastroenterol. | pmid:24914324 |
| Glatz M and Muellegger RR | Drug-associated aquagenic wrinkling of the palms in an atopic male patient. | 2014 | BMJ Case Rep | pmid:24903725 |
| DiCicco M et al. | In vitro synergism of fosfomycin and clarithromycin antimicrobials against methicillin-resistant Staphylococcus pseudintermedius. | 2014 | BMC Microbiol. | pmid:24886369 |
| Noonan KA et al. | Targeting immune suppression with PDE5 inhibition in end-stage multiple myeloma. | 2014 | Cancer Immunol Res | pmid:24878583 |
| Gong EJ et al. | Meta-analysis of first-line triple therapy for helicobacter pylori eradication in Korea: is it time to change? | 2014 | J. Korean Med. Sci. | pmid:24851029 |
| Jeon HK and Kim GH | Does standard triple therapy still have a role in first-line Helicobacter pylori eradication in Korea? | 2014 | J. Korean Med. Sci. | pmid:24851014 |
| Jarand J and Field SK | Embrace simplicity when treating lady windermere. | 2014 | Chest | pmid:25091749 |
| Khalili N | Sunny hypomania associated with clarithromycin: a case report. | 2014 | J Clin Psychopharmacol | pmid:24717249 |
| Onyekwere CA et al. | Rabeprazole, clarithromycin, and amoxicillin Helicobacter pylori eradication therapy: report of an efficacy study. | 2014 | World J. Gastroenterol. | pmid:24707145 |
| Wu JY et al. | Detection of genotypic clarithromycin-resistant Helicobacter pylori by string tests. | 2014 | World J. Gastroenterol. | pmid:24695835 |
| Sugimoto M et al. | Efficacy of tailored Helicobacter pylori eradication treatment based on clarithromycin susceptibility and maintenance of acid secretion. | 2014 | Helicobacter | pmid:24690010 |
| Liu KY et al. | Efficacy and pharmacological mechanism of pronase-enhanced low-dose antibiotics for Helicobacter pylori eradication. | 2014 | Antimicrob. Agents Chemother. | pmid:24687504 |
| Ikawa K et al. | Pharmacokinetic modelling of serum and bronchial concentrations for clarithromycin and telithromycin, and site-specific pharmacodynamic simulation for their dosages. | 2014 | J Clin Pharm Ther | pmid:24661290 |
| Varvyanskaya A and Lopatin A | Efficacy of long-term low-dose macrolide therapy in preventing early recurrence of nasal polyps after endoscopic sinus surgery. | 2014 | Int Forum Allergy Rhinol | pmid:24659566 |
| Lee SH et al. | Detection and assessment of clarithromycin inducible resistant strains among Korean Mycobacterium abscessus clinical strains: PCR methods. | 2014 | J. Clin. Lab. Anal. | pmid:24652818 |
| Binh TT et al. | Discovery of novel mutations for clarithromycin resistance in Helicobacter pylori by using next-generation sequencing. | 2014 | J. Antimicrob. Chemother. | pmid:24648504 |
| Tursi A et al. | Decreasing efficacy of the standard seven-day triple therapy containing amoxycillin and clarithromycin in curing Helicobacter pylori infection in clinical setting in Italy: a 10-year follow-up study. | 2014 | Panminerva Med | pmid:24637473 |
| Wei Z et al. | Rome III criteria cannot distinguish patients with chronic gastritis from those functional dyspepsia patients. | 2014 | Helicobacter | pmid:24617669 |
| Wu JY et al. | Feasibility of shortening 14-day hybrid therapy while maintaining an excellent Helicobacter pylori eradication rate. | 2014 | Helicobacter | pmid:24612093 |
| Settin A et al. | Cure rate of Helicobacter pylori infection in Egyptian children related to CYP2C19 gene polymorphism. | 2014 | Indian J Gastroenterol | pmid:24610583 |
| Ali Habib HS et al. | Effect of sequential versus standard Helicobacter pylori eradication therapy on the associated iron deficiency anemia in children. | 2013 Sep-Oct | Indian J Pharmacol | pmid:24130381 |
| Mégraud F | Current recommendations for Helicobacter pylori therapies in a world of evolving resistance. | 2013 Nov-Dec | Gut Microbes | pmid:23929066 |
| Suzaki I et al. | Enhancement of thioredoxin production from nasal epithelial cells by the macrolide antibiotic, clarithromycin in vitro. | 2013 May-Jun | In Vivo | pmid:23606690 |
| Dajani AI et al. | Do probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy? | 2013 May-Jun | Saudi J Gastroenterol | pmid:23680708 |
| Petitto J et al. | Successful clarithromycin desensitization in a macrolide-sensitive pediatric patient. | 2013 May-Jun | J Allergy Clin Immunol Pract | pmid:24565493 |
| Cottle LE et al. | A multinational outbreak of histoplasmosis following a biology field trip in the Ugandan rainforest. | 2013 Mar-Apr | J Travel Med | pmid:23464714 |
| Molina-Infante J and Gisbert JP | [Update on the efficacy of triple therapy for Helicobacter pylori infection and clarithromycin resistance rates in Spain (2007-2012)]. | 2013 Jun-Jul | Gastroenterol Hepatol | pmid:23623461 |
| Razafimahefa SH et al. | [Helicobacter pylori: what eradication regimen in a tropical area after the failure of two separate lines of eradication including metronidazole and clarithromycin?]. | 2013 Jan-Mar | Med Sante Trop | pmid:23360589 |
| Mandras N et al. | Antibacterial efficacy and drug-induced tooth discolouration of antibiotic combinations for endodontic regenerative procedures. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755774 |
| Avci O et al. | A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. | 2013 | J Dermatolog Treat | pmid:21923567 |
| Lee HJ et al. | Eradication of Helicobacter pylori according to 23S ribosomal RNA point mutations associated with clarithromycin resistance. | 2013 | J. Infect. Dis. | pmid:23801607 |
| Shallom SJ et al. | New rapid scheme for distinguishing the subspecies of the Mycobacterium abscessus group and identifying Mycobacterium massiliense isolates with inducible clarithromycin resistance. | 2013 | J. Clin. Microbiol. | pmid:23804391 |
| Lee G et al. | Nodular bronchiectatic Mycobacterium avium complex pulmonary disease. Natural course on serial computed tomographic scans. | 2013 | Ann Am Thorac Soc | pmid:23952847 |
| Liou JM et al. | Sequential versus triple therapy for the first-line treatment of Helicobacter pylori: a multicentre, open-label, randomised trial. | 2013 | Lancet | pmid:23158886 |
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