clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lara-MartÃn PA et al. | Occurrence, distribution and partitioning of nonionic surfactants and pharmaceuticals in the urbanized Long Island Sound Estuary (NY). | 2014 | Mar. Pollut. Bull. | pmid:24467856 |
| Saadat A et al. | The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler. | 2014 | J. Pharm. Pharmacol. | pmid:24329164 |
| Rajput P et al. | Bifunctional capsular dosage form: novel fanicular cylindrical gastroretentive system of clarithromycin and immediate release granules of ranitidine HCl for simultaneous delivery. | 2014 | Int J Pharm | pmid:24309435 |
| Katayama M et al. | Preliminary study of effects of multiple oral dosing of clarithromycin on the pharmacokinetics of cyclosporine in dogs. | 2014 | J. Vet. Med. Sci. | pmid:24189617 |
| Furuta T et al. | Effect of dosing schemes of amoxicillin on eradication rates of Helicobacter pylori with amoxicillin-based triple therapy. | 2014 | J Clin Pharmacol | pmid:24122836 |
| Ratzinger F et al. | Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity. | 2014 | Sci Rep | pmid:25500904 |
| Shahbazi Niaz M et al. | Investigation into physical-chemical variables affecting the manufacture and dissolution of wet-milled clarithromycin nanoparticles. | 2014 | Pharm Dev Technol | pmid:24093825 |
| Maev IV et al. | [Eradication therapy for Helicobacter pylori infection: review of world trends]. | 2014 | Ter. Arkh. | pmid:24779078 |
| Katagiri S et al. | [Case report; Disseminated Mycobacterium abscessus infection with hemophagocytic syndrome during treatment of chronic lymphocytic leukemia]. | 2014 | Nippon Naika Gakkai Zasshi | pmid:24796145 |
| Trotti LM et al. | Improvement in daytime sleepiness with clarithromycin in patients with GABA-related hypersomnia: Clinical experience. | 2014 | J. Psychopharmacol. (Oxford) | pmid:24306133 |
| Nie W et al. | [The analysis of species identification and susceptibility testing of Mycobacterium abscessus]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262693 |
| Campanale M et al. | Nickel free-diet enhances the Helicobacter pylori eradication rate: a pilot study. | 2014 | Dig. Dis. Sci. | pmid:24595654 |
| Schuhfried G et al. | Gilles de la Tourette Syndrome caused by Mycoplasma pneumoniae successfully treated with macrolides. | 2014 | Klin Padiatr | pmid:25153913 |
| Svanström H et al. | Use of clarithromycin and roxithromycin and risk of cardiac death: cohort study. | 2014 | BMJ | pmid:25139799 |
| Giamarellos-Bourboulis EJ et al. | Effect of clarithromycin in patients with suspected Gram-negative sepsis: results of a randomized controlled trial. | 2014 | J. Antimicrob. Chemother. | pmid:24292991 |
| Zhao Y and Hu ZY | Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate. | 2014 | Br. J. Pharmacol. | pmid:24283665 |
| Harvey E and Varatharaj A | Round pneumonia. | 2014 | QJM | pmid:23708793 |
| Tsovolou EC et al. | Effect of clarithromycin in experimental empyema by multidrug-resistant Pseudomonas aeruginosa. | 2014 | APMIS | pmid:23656439 |
| Altman E et al. | Lipopolysaccharide glycotyping of clarithromycin-resistant and clarithromycin-susceptible Canadian isolates of Helicobacter pylori. | 2014 | Can. J. Microbiol. | pmid:24392924 |
| Oztürk K et al. | Diagnosis of helicobacter pylori infection. | 2014 | Turk J Gastroenterol | pmid:25141328 |
| Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
| Jung YS et al. | [Trends in the eradication rates of Helicobacter pylori infection in Daegu and Gyeongsangbuk-do, Korea: multicenter study over 13 years]. | 2014 | Korean J Gastroenterol | pmid:24561694 |
| Vanderpas J et al. | Follow-up of Helicobacter pylori infection in children over two decades (1988-2007): persistence, relapse and acquisition rates. | 2014 | Epidemiol. Infect. | pmid:23809783 |
| Koh S et al. | Visualization of the meibomian glands by means of noncontact mobile-type meibography (Meibopen) in a 16-year-old girl with unilateral marginal staphylococcal keratitis. | 2014 | J AAPOS | pmid:24568999 |
| Ke AB et al. | Itraconazole and clarithromycin as ketoconazole alternatives for clinical CYP3A inhibition studies. | 2014 | Clin. Pharmacol. Ther. | pmid:24747234 |
| Oğuz M and Mihçiokur H | Environmental risk assessment of selected pharmaceuticals in Turkey. | 2014 | Environ. Toxicol. Pharmacol. | pmid:24929476 |
| Ghosh N et al. | Clarithromycin overcomes resistance to lenalidomide and dexamethasone in multiple myeloma. | 2014 | Am. J. Hematol. | pmid:24723438 |
| Gisbert JP et al. | Third-line rescue therapy with bismuth-containing quadruple regimen after failure of two treatments (with clarithromycin and levofloxacin) for H. pylori infection. | 2014 | Dig. Dis. Sci. | pmid:24126798 |
| Tranos P et al. | Bilateral diffuse iris atrophy after the use of oral clarithromycin. | 2014 | Cutan Ocul Toxicol | pmid:23763291 |
| Kuroda H et al. | [Three cases of lenalidomide-resistant IgA myeloma for which a response was regained after the addition of clarithromycin]. | 2014 | Gan To Kagaku Ryoho | pmid:25248908 |
| Bouricha M et al. | Mycobacterium marinum infection following contact with reptiles: vivarium granuloma. | 2014 | Int. J. Infect. Dis. | pmid:24530276 |
| Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
| Homma S et al. | The successful management of respiratory complications with long-term, low-dose macrolide administration in pediatric heart transplant recipients. | 2014 | Int Heart J | pmid:25297501 |
| Renvoisé A et al. | Significant difference in drug susceptibility distribution between Mycobacterium avium and Mycobacterium intracellulare. | 2014 | J. Clin. Microbiol. | pmid:25274991 |
| Tu S and Yang H | [Progress in the treatment of Helicobacter pylori infection]. | 2014 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:25269503 |
| Malfertheiner P and Selgrad M | Helicobacter pylori. | 2014 | Curr. Opin. Gastroenterol. | pmid:25268839 |
| Ito Y et al. | The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease. | 2014 | BMC Infect. Dis. | pmid:25266993 |
| de Miguel-Martinez I et al. | [Bacteriemia due to Mycobacterium canariasense in an oncohematological patient with a long-term central device]. | 2014 | Enferm. Infecc. Microbiol. Clin. | pmid:25262854 |
| Gui J et al. | [Subspecies identification for Mycobacterium abscessus group]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262692 |
| Ghrew MH et al. | Successful renal transplant in patient with controlled pulmonary non-tuberculous mycobacterium infection. | 2014 | Libyan J Med | pmid:25249307 |
| Yoon KH et al. | Clarithromycin-based standard triple therapy can still be effective for Helicobacter pylori eradication in some parts of the Korea. | 2014 | J. Korean Med. Sci. | pmid:25246742 |
| Higgins JW et al. | Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1. | 2014 | Drug Metab. Dispos. | pmid:25106415 |
| Matongo F and Nwodo UU | In vitro assessment of Helicobacter pylori ureases inhibition by honey fractions. | 2014 | Arch. Med. Res. | pmid:25240315 |
| Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
| Nilsson MF and Webster WS | Effects of macrolide antibiotics on rat embryonic heart function in vitro. | 2014 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:24753334 |
| Peng YC et al. | Clarithromycin modulates Helicobacter pylori-induced activation of nuclear factor-κB through classical and alternative pathways in gastric epithelial cells. | 2014 | Clin. Exp. Med. | pmid:23129507 |
| Wallace RJ et al. | Macrolide/Azalide therapy for nodular/bronchiectatic mycobacterium avium complex lung disease. | 2014 | Chest | pmid:24457542 |
| Molina-Infante J and Gisbert JP | Optimizing clarithromycin-containing therapy for Helicobacter pylori in the era of antibiotic resistance. | 2014 | World J. Gastroenterol. | pmid:25132750 |
| Heo J et al. | A randomised clinical trial of 10-day concomitant therapy and standard triple therapy for Helicobacter pylori eradication. | 2014 | Dig Liver Dis | pmid:25132282 |
| Lebedeva MV et al. | Clarithromycin as a chiral selector for enantioseparation of basic compounds in nonaqueous capillary electrophoresis. | 2014 | Electrophoresis | pmid:25100556 |
| Katayama M et al. | Preliminary study of interaction of clarithromycin with tacrolimus in cats. | 2014 | J. Vet. Med. Sci. | pmid:25099737 |
| Park CS et al. | Pretreatment antimicrobial susceptibility-guided vs. clarithromycin-based triple therapy for Helicobacter pylori eradication in a region with high rates of multiple drug resistance. | 2014 | Am. J. Gastroenterol. | pmid:25091062 |
| Cicek-Senturk G et al. | Acute mercury poisoning presenting as fever of unknown origin in an adult woman: a case report. | 2014 | J Med Case Rep | pmid:25084829 |
| Bilgin M et al. | Acute coronary syndrome secondary to clarithromycin: the first case and review of the literature. | 2014 | Turk Kardiyol Dern Ars | pmid:25080953 |
| Hsu PI et al. | Randomized controlled trial comparing 7-day triple, 10-day sequential, and 7-day concomitant therapies for Helicobacter pylori infection. | 2014 | Antimicrob. Agents Chemother. | pmid:25070099 |
| Acosta CP et al. | [Determination of single nucleotide mutations in the 23S rRNA gene of Helicobacter pylori related to clarithromycin resistance in a population from Cauca, Colombia]. | 2014 | Biomedica | pmid:24968047 |
| Lee JW et al. | GenoType HelicoDR test in the determination of antimicrobial resistance of Helicobacter pylori in Korea. | 2014 | Scand. J. Gastroenterol. | pmid:24957849 |
| Raffaldi I et al. | An atypical deep neck infection in a two-year-old child. | 2014 | Infez Med | pmid:24955801 |
| Oh DH et al. | Efficacy of hybrid therapy as first-line regimen for Helicobacter pylori infection compared with sequential therapy. | 2014 | J. Gastroenterol. Hepatol. | pmid:24955448 |
| Patel K et al. | Oral delivery of paclitaxel nanocrystal (PNC) with a dual Pgp-CYP3A4 inhibitor: preparation, characterization and antitumor activity. | 2014 | Int J Pharm | pmid:24954663 |
| Vafaeimanesh J et al. | Expression comparison of azithromycin and clarithromycin in triple-therapy regimens for eradication of Helicobacter pylori in hemodialysis patients. | 2014 | Saudi J Kidney Dis Transpl | pmid:24434382 |
| Bonferoni MC et al. | Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid. | 2014 | Eur J Pharm Biopharm | pmid:24384070 |
| Liu CP et al. | NO-releasing xanthine KMUP-1 bonded by simvastatin attenuates bleomycin-induced lung inflammation and delayed fibrosis. | 2014 | Pulm Pharmacol Ther | pmid:23518214 |
| Philips RC et al. | Mycobacterium fortuitum infection arising in a new tattoo. | 2014 | Dermatol. Online J. | pmid:24945647 |
| Klesiewicz K et al. | PCR-RFLP detection of point mutations A2143G and A2142G in 23S rRNA gene conferring resistance to clarithromycin in Helicobacter pylori strains. | 2014 | Acta Biochim. Pol. | pmid:24927236 |
| Sugimoto M and Furuta T | Efficacy of tailored Helicobacter pylori eradication therapy based on antibiotic susceptibility and CYP2C19 genotype. | 2014 | World J. Gastroenterol. | pmid:24914361 |
| Heo J and Jeon SW | Optimal treatment strategy for Helicobacter pylori: era of antibiotic resistance. | 2014 | World J. Gastroenterol. | pmid:24914324 |
| Jarand J and Field SK | Embrace simplicity when treating lady windermere. | 2014 | Chest | pmid:25091749 |
| Zhao LJ et al. | Helicobacter pylori isolates from ethnic minority patients in Guangxi: resistance rates, mechanisms, and genotype. | 2014 | World J. Gastroenterol. | pmid:24782630 |
| Peretz A et al. | Resistance of Helicobacter pylori to tetracycline, amoxicillin, clarithromycin and metronidazole in Israeli children and adults. | 2014 | J. Antibiot. | pmid:24781955 |
| Nishida T et al. | Comparative study of esomeprazole and lansoprazole in triple therapy for eradication of Helicobacter pylori in Japan. | 2014 | World J. Gastroenterol. | pmid:24764674 |
| Zhou L et al. | Relationship of Helicobacter pylori eradication with gastric cancer and gastric mucosal histological changes: a 10-year follow-up study. | 2014 | Chin. Med. J. | pmid:24762588 |
| Luo Q et al. | [Clinical effect of clarithromycin therapy in patients with chronic rhinosinusitis]. | 2014 | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:24742507 |
| Trotti LM et al. | Further experience using clarithromycin in patients with Kleine-Levin syndrome. | 2014 | J Clin Sleep Med | pmid:24733995 |
| Khalili N | Sunny hypomania associated with clarithromycin: a case report. | 2014 | J Clin Psychopharmacol | pmid:24717249 |
| Onyekwere CA et al. | Rabeprazole, clarithromycin, and amoxicillin Helicobacter pylori eradication therapy: report of an efficacy study. | 2014 | World J. Gastroenterol. | pmid:24707145 |
| Wu JY et al. | Detection of genotypic clarithromycin-resistant Helicobacter pylori by string tests. | 2014 | World J. Gastroenterol. | pmid:24695835 |
| Sugimoto M et al. | Efficacy of tailored Helicobacter pylori eradication treatment based on clarithromycin susceptibility and maintenance of acid secretion. | 2014 | Helicobacter | pmid:24690010 |
| Liu KY et al. | Efficacy and pharmacological mechanism of pronase-enhanced low-dose antibiotics for Helicobacter pylori eradication. | 2014 | Antimicrob. Agents Chemother. | pmid:24687504 |
| Ikawa K et al. | Pharmacokinetic modelling of serum and bronchial concentrations for clarithromycin and telithromycin, and site-specific pharmacodynamic simulation for their dosages. | 2014 | J Clin Pharm Ther | pmid:24661290 |
| Varvyanskaya A and Lopatin A | Efficacy of long-term low-dose macrolide therapy in preventing early recurrence of nasal polyps after endoscopic sinus surgery. | 2014 | Int Forum Allergy Rhinol | pmid:24659566 |
| Karaolia P et al. | Reduction of clarithromycin and sulfamethoxazole-resistant Enterococcus by pilot-scale solar-driven Fenton oxidation. | 2014 | Sci. Total Environ. | pmid:24012892 |
| Rizzo A et al. | Antimicrobial effect of natural polyphenols with or without antibiotics on Chlamydia pneumoniae infection in vitro. | 2014 | Microb. Drug Resist. | pmid:23952319 |
| Zhang J et al. | Ocular penetration and pharmacokinetics of topical clarithromycin eye drops to rabbits. | 2014 | J Ocul Pharmacol Ther | pmid:24199739 |
| Ali Habib HS et al. | Effect of sequential versus standard Helicobacter pylori eradication therapy on the associated iron deficiency anemia in children. | 2013 Sep-Oct | Indian J Pharmacol | pmid:24130381 |
| Mégraud F | Current recommendations for Helicobacter pylori therapies in a world of evolving resistance. | 2013 Nov-Dec | Gut Microbes | pmid:23929066 |
| Suzaki I et al. | Enhancement of thioredoxin production from nasal epithelial cells by the macrolide antibiotic, clarithromycin in vitro. | 2013 May-Jun | In Vivo | pmid:23606690 |
| Dajani AI et al. | Do probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy? | 2013 May-Jun | Saudi J Gastroenterol | pmid:23680708 |
| Petitto J et al. | Successful clarithromycin desensitization in a macrolide-sensitive pediatric patient. | 2013 May-Jun | J Allergy Clin Immunol Pract | pmid:24565493 |
| Cottle LE et al. | A multinational outbreak of histoplasmosis following a biology field trip in the Ugandan rainforest. | 2013 Mar-Apr | J Travel Med | pmid:23464714 |
| Molina-Infante J and Gisbert JP | [Update on the efficacy of triple therapy for Helicobacter pylori infection and clarithromycin resistance rates in Spain (2007-2012)]. | 2013 Jun-Jul | Gastroenterol Hepatol | pmid:23623461 |
| Razafimahefa SH et al. | [Helicobacter pylori: what eradication regimen in a tropical area after the failure of two separate lines of eradication including metronidazole and clarithromycin?]. | 2013 Jan-Mar | Med Sante Trop | pmid:23360589 |
| Mandras N et al. | Antibacterial efficacy and drug-induced tooth discolouration of antibiotic combinations for endodontic regenerative procedures. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755774 |
| Srivastava S et al. | Therapeutic drug management: is it the future of multidrug-resistant tuberculosis treatment? | 2013 | Eur. Respir. J. | pmid:24293417 |
| Yakoob J et al. | Low rate of recurrence of Helicobacter pylori infection in spite of high clarithromycin resistance in Pakistan. | 2013 | BMC Gastroenterol | pmid:23433429 |
| Kato H et al. | Addition of clarithromycin to lenalidomide/low-dose dexamethasone was effective in a case of relapsed myeloma after long-term use of lenalidomide. | 2013 | Ann. Hematol. | pmid:23625297 |
| Kim SG et al. | Helicobacter pylori eradication on iatrogenic ulcer by endoscopic resection of gastric tumour: a prospective, randomized, placebo-controlled multi-centre trial. | 2013 | Dig Liver Dis | pmid:23333104 |
| Lim JH et al. | Clinical outcomes of two-week sequential and concomitant therapies for Helicobacter pylori eradication: a randomized pilot study. | 2013 | Helicobacter | pmid:23305083 |
| Feng Z et al. | Dissociative disorder induced by clarithromycin combined with rabeprazole in a patient with gastritis. | 2013 | J. Int. Med. Res. | pmid:23569151 |
| Cai M et al. | Macrolides inhibit cytokine production by alveolar macrophages in bronchiolitis obliterans organizing pneumonia. | 2013 | Immunobiology | pmid:23199585 |