clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Granda MartÃn MJ et al. | [Mycoplasma-associated acute hepatitis in an adult patient without pulmonary involvement]. | Gastroenterol Hepatol | pmid:24569138 | |
Alsohaibani F et al. | Prospective trial in Saudi Arabia comparing the 14-day standard triple therapy with the 10-day sequential therapy for treatment of Helicobacter pylori infection. | Saudi J Gastroenterol | pmid:26228365 | |
Zullo A et al. | Furazolidone-based therapies for Helicobacter pylori infection: a pooled-data analysis. | Saudi J Gastroenterol | pmid:22249086 | |
Monego F et al. | Molecular identification and typing of Mycobacterium massiliense isolated from postsurgical infections in Brazil. | Braz J Infect Dis | pmid:22230849 | |
Kim MD et al. | Ergotamine-induced upper extremity ischemia: a case report. | Korean J Radiol | pmid:15968153 | |
Dharmalingam S et al. | Relationship of plasmid profile with the antibiotic sensitivity pattern of Helicobacter pylori isolates from peptic ulcer disease patients in Chennai. | Indian J Med Microbiol | pmid:17643038 | |
Kekilli M et al. | Inefficacy of triple therapy and comparison of two different bismuth-containing quadruple regimens as a firstline treatment option for helicobacter pylori. | Saudi J Gastroenterol | pmid:27748322 | |
Ikeda H et al. | Severe Disseminated Mycobacterium avium Infection in a Patient with a Positive Serum Autoantibody to Interferon-γ. | Intern. Med. | pmid:27746449 | |
Siemens J et al. | Transport of pharmaceuticals in columns of a wastewater-irrigated Mexican clay soil. | J. Environ. Qual. | pmid:20830907 | |
Ubhayawardana NL et al. | Detection of clarithromycin-resistant Helicobacter pylori strains in a dyspeptic patient population in Sri Lanka by polymerase chain reaction-restriction fragment length polymorphism. | Indian J Med Microbiol | pmid:26068338 | |
Dzieciatkowski T et al. | Comparison of two methods used for monitoring low-copy cytomegalovirus infection in a patient with chronic myeloid leukemia after unrelated umbilical cord blood transplantation. | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:17557148 | |
Baylor P and Larson R | Mycobacterium avium septicemia with ARDS in a patient with diabetes mellitus and no other known immune-compromising condition. | J Intensive Care Med | pmid:19188269 | |
Kim HY et al. | Allele-specific duplex polymerase chain reaction to differentiate Mycobacterium abscessus subspecies and to detect highly clarithromycin-resistant isolates. | Indian J Med Microbiol | pmid:27514964 | |
Colomina RodrÃguez J et al. | [Impact of Integrated Model for Rational Use of Antibiotics in a health area (project MIURA)]. | Rev. Esp. Salud Publica | pmid:20661527 | |
Yang X et al. | Comparison Between Sequential Therapy and Modified Bismuth-Included Quadruple Therapy for Helicobacter pylori Eradication in Chinese Patients. | Am J Ther | pmid:25923229 | |
Karakaya G et al. | Determining safe antibiotics for drug hypersensitive patients with the alternative method of double-triple test. | Allergol Immunopathol (Madr) | pmid:19080798 | |
Araújo-Filho I et al. | Prevalence of Helicobacter pylori infection in advanced gastric carcinoma. | Arq Gastroenterol | pmid:17406757 | |
Martins GM et al. | MOLECULAR DETECTION OF CLARITHROMYCIN AND FLUOROQUINOLONES RESISTANCE IN HELICOBACTER PYLORI INFECTION, DIRECTLY APPLIED TO GASTRIC BIOPSIES, IN AN URBAN BRAZILIAN POPULATION. | Arq Gastroenterol | pmid:27305419 | |
Pombo Romero J et al. | [Evaluation of the pilot program of medicine dispensation in customized doses in Galicia [Spain]]. | Gac Sanit | pmid:17306181 | |
Rech TF et al. | Helicobacter pylori eradication: influence of interleukin-1beta -31 C/T polymorphism. | Braz J Infect Dis | pmid:30048609 | |
Wang B et al. | In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates. | Swiss Med Wkly | pmid:30044468 | |
Lage R et al. | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease. | An Bras Dermatol | pmid:25672306 | |
Melo-Cristino J et al. | [Antimicrobial susceptibility of Streptococcus pyogenes, Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis from community acquired respiratory infections in 2000]. | Acta Med Port | pmid:11878155 | |
Bartnik W | Clinical aspects of Helicobacter pylori infection. | Pol. Arch. Med. Wewn. | pmid:18714738 | |
Kempen JH | Medical management of human immunodeficiency virus infection. | Indian J Ophthalmol | pmid:18711266 | |
Roig J et al. | 13--Antibiotic therapy of community-acquired pneumonia (CAP) caused by atypical agents. | Med Mal Infect | pmid:17095177 | |
Fernández JA et al. | [The hospital faced with a prolonged Legionella outbreak]. | Gac Sanit | pmid:15324645 | |
Bachir M et al. | Primary antibiotic resistance and its relationship with cagA and vacA genes in Helicobacter pylori isolates from Algerian patients. | Braz. J. Microbiol. | pmid:29452847 | |
Buzás GM et al. | Six regimens for the eradication of Helicobacter pylori (Hp) in duodenal ulcer patients: three consecutive trials (1995-1999). | J. Physiol. Paris | pmid:11595472 | |
Mishra A et al. | A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin. | Indian J Pharmacol | pmid:25298587 | |
Lew EA | Clarithromycin, lansoprazole, and metronidazole eradicated Helicobacter pylori infection in chronic renal insufficiency. | ACP J. Club | pmid:15122860 | |
pmid:11817788 | ||||
Torpiano P and Pace D | Clinically-diagnosed Mediterranean Spotted Fever in Malta. | Travel Med Infect Dis | pmid:29462726 | |
Bermejo Vicedo T et al. | [A pharmacoeconomic study of in-hospital treatment against community-acquired pneumonia]. | Farm Hosp | pmid:15012176 | |
Cohen ND et al. | Use of Liposomal Gentamicin for Treatment of 5 Foals with Experimentally Induced Rhodococcus equi Pneumonia. | J. Vet. Intern. Med. | pmid:26692327 | |
Liang CM et al. | Levofloxacin-containing second-line anti-Helicobacter pylori eradication in Taiwanese real-world practice. | Biomed J | pmid:25163495 | |
Zhu C et al. | Prevalence and antimicrobial susceptibility of Ureaplasma urealyticum and Mycoplasma hominis in Chinese women with genital infectious diseases. | Indian J Dermatol Venereol Leprol | pmid:22565456 | |
Wang J et al. | Two-week triple therapy has a higher Helicobacter pylori eradication rate than 1-week therapy: A single-center randomized study. | Saudi J Gastroenterol | pmid:26655129 | |
Pellicano R and Fagoonee S | One or two weeks of treatment with Helicobacter Pylori ''standard'' triple therapy in the year 2015? | Saudi J Gastroenterol | pmid:26655127 | |
Atukorale V et al. | An unusual antibiotic susceptibility pattern in a strain isolated from the chesapeake bay. | Int J Mycobacteriol | pmid:28317803 | |
Moreira C et al. | Symmetrical drug-related intertriginous and flexural exanthema induced by clarithromycin. | An Bras Dermatol | pmid:28954125 | |
Cavkaytar O et al. | Testing for clarithromycin hypersensitivity: A diagnostic challenge in childhood. | J Allergy Clin Immunol Pract | pmid:26489714 | |
Dajani A et al. | Importance of Helicobacter pylori eradcation for maintenance of remission of drug associated peptic ulcer disease. | Saudi J Gastroenterol | pmid:19858579 | |
Doorakkers E et al. | Helicobacter pylori eradication in the Swedish population. | Scand. J. Gastroenterol. | pmid:28323552 | |
Moreira A et al. | Is Helicobacter pylori infection associated with chronic idiopathic urticaria? | Allergol Immunopathol (Madr) | pmid:12890412 | |
Clark SE et al. | Identification of a multidrug efflux pump in Flavobacterium johnsoniae. | Vet. Res. | pmid:19558960 | |
Yamazhan T et al. | In vitro activities of various antimicrobials against Brucella melitensis strains in the Aegean region in Turkey. | Med Princ Pract | pmid:16220015 | |
Pachot JI et al. | Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model. | J Pharm Pharm Sci | pmid:12753725 | |
Lin TY et al. | An open-label, randomized comparison of levofloxacin and amoxicillin/clavulanate plus clarithromycin for the treatment of hospitalized patients with community-acquired pneumonia. | Chang Gung Med J | pmid:17939262 | |
Radzikowska E et al. | Clarithromycin Decreases IL-6 Concentration in Serum and BAL Fluid in Patients with Cryptogenic Organizing Pneumonia. | Adv Clin Exp Med | pmid:28028949 |