| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sharara AI et al. | Letter: clarithromycin dose for H. pylori therapy remains unresolved--authors' reply. | 2015 | Aliment. Pharmacol. Ther. | pmid:26238584 |
| Cardenas VM et al. | Rabeprazole containing triple therapy to eradicate Helicobacter pylori infection on the Texas-Mexican border. | 2006 | Aliment. Pharmacol. Ther. | pmid:16393310 |
| Kamada T et al. | The long-term effect of Helicobacter pylori eradication therapy on symptoms in dyspeptic patients with fundic atrophic gastritis. | 2003 | Aliment. Pharmacol. Ther. | pmid:12869086 |
| Miehlke S et al. | Esomeprazole-based one-week triple therapy with clarithromycin and metronidazole is effective in eradicating Helicobacter pylori in the absence of antimicrobial resistance. | 2003 | Aliment. Pharmacol. Ther. | pmid:14535873 |
| Neri M et al. | Role of antibiotic sensitivity testing before first-line Helicobacter pylori eradication treatments. | 2003 | Aliment. Pharmacol. Ther. | pmid:14535876 |
| Lai KC et al. | Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in nonsteroidal anti-inflammatory drug users--a randomized trial. | 2003 | Aliment. Pharmacol. Ther. | pmid:14535877 |
| Sasaki A et al. | Long-term observation of reflux oesophagitis developing after Helicobacter pylori eradication therapy. | 2003 | Aliment. Pharmacol. Ther. | pmid:12823156 |
| Khurana R et al. | Meta-analysis: Helicobacter pylori eradication treatment efficacy in children. | 2007 | Aliment. Pharmacol. Ther. | pmid:17305754 |
| Yousfi MM et al. | One-week triple therapy with omeprazole, amoxycillin and clarithromycin for treatment of Helicobacter pylori infection. | 1996 | Aliment. Pharmacol. Ther. | pmid:8853767 |
| Gisbert JP and Calvet X | Review article: non-bismuth quadruple (concomitant) therapy for eradication of Helicobater pylori. | 2011 | Aliment. Pharmacol. Ther. | pmid:21745241 |
| Hawkey CJ et al. | Safety and efficacy of 7-day rabeprazole- and omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with documented peptic ulcer disease. | 2003 | Aliment. Pharmacol. Ther. | pmid:12694089 |
| Leiper K et al. | Clinical trial: randomized study of clarithromycin versus placebo in active Crohn's disease. | 2008 | Aliment. Pharmacol. Ther. | pmid:18315579 |
| Zullo A et al. | Primary antibiotic resistance in Helicobacter pylori strains isolated in northern and central Italy. | 2007 | Aliment. Pharmacol. Ther. | pmid:17539982 |
| Nista EC et al. | Bacillus clausii therapy to reduce side-effects of anti-Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial. | 2004 | Aliment. Pharmacol. Ther. | pmid:15569121 |
| Savarino V et al. | The impact of antibiotic resistance on the efficacy of three 7-day regimens against Helicobacter pylori. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886045 |
| Wang WH et al. | High prevalence of Helicobacter pylori infection with dual resistance to metronidazole and clarithromycin in Hong Kong. | 2000 | Aliment. Pharmacol. Ther. | pmid:10886046 |
| Chen PY et al. | Letter: levofloxacin resistance - a challenge for treatment of Helicobacter pylori infection. Authors' reply. | 2017 | Aliment. Pharmacol. Ther. | pmid:28074519 |
| Zamani M et al. | Letter: levofloxacin resistance - a challenge for the treatment of Helicobacter pylori infection. | 2017 | Aliment. Pharmacol. Ther. | pmid:28074507 |
| Drouet M et al. | [Unusual clinical form of amoxicillin allergy]. | 1996 | Allerg Immunol (Paris) | pmid:9011169 |
| Can C et al. | Symmetrical drug-related intertriginous and flexural exanthema induced by two different antibiotics. | Allergol Immunopathol (Madr) | pmid:23253684 | |
| Gangemi S et al. | Immediate reaction to clarithromycin. | 2001 Jan-Feb | Allergol Immunopathol (Madr) | pmid:11449533 |
| Gaig P et al. | Efficacy of the eradication of Helicobacter pylori infection in patients with chronic urticaria. A placebo-controlled double blind study. | 2002 Sep-Oct | Allergol Immunopathol (Madr) | pmid:12396958 |
| Karakaya G et al. | Determining safe antibiotics for drug hypersensitive patients with the alternative method of double-triple test. | Allergol Immunopathol (Madr) | pmid:19080798 | |
| Malheiro D et al. | Nimesulide-induced fixed drug eruption. | 2005 Sep-Oct | Allergol Immunopathol (Madr) | pmid:16287549 |
| Seitz CS et al. | Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. | Allergol Immunopathol (Madr) | pmid:21269750 | |
| Moreira A et al. | Is Helicobacter pylori infection associated with chronic idiopathic urticaria? | Allergol Immunopathol (Madr) | pmid:12890412 | |
| Brož P et al. | Nonirritant intradermal skin test concentrations of ciprofloxacin, clarithromycin, and rifampicin. | 2012 | Allergy | pmid:22435670 |
| Igea JM and Lázaro M | Hypersensitivity reaction to clarithromycin. | 1998 | Allergy | pmid:9491242 |
| Ben-Shoshan M et al. | Anaphylactic reaction to clarithromycin in a child. | 2009 | Allergy | pmid:19222423 |
| Siddiqui S and Brightling CE | Airways disease: phenotyping heterogeneity using measures of airway inflammation. | 2007 | Allergy Asthma Clin Immunol | pmid:20525145 |
| Xepapadaki P et al. | Atypical bacteria and macrolides in asthma. | 2008 | Allergy Asthma Clin Immunol | pmid:20525132 |
| Desrosiers M et al. | Canadian clinical practice guidelines for acute and chronic rhinosinusitis. | 2011 | Allergy Asthma Clin Immunol | pmid:21310056 |
| Wedi B et al. | Urticaria and infections. | 2009 | Allergy Asthma Clin Immunol | pmid:20066173 |
| Thong BY | Update on the management of antibiotic allergy. | 2010 | Allergy Asthma Immunol Res | pmid:20358021 |
| Park SJ et al. | Fulminant and Fatal Multiple Organ Failure in a 12-Year-Old Boy With Mycoplasma pneumoniae Infection. | 2012 | Allergy Asthma Immunol Res | pmid:22211173 |
| Kim MH et al. | A case of chlorpheniramine maleate-induced hypersensitivity with aspirin intolerance. | 2011 | Allergy Asthma Immunol Res | pmid:21217928 |
| Hong SJ | The Role of Mycoplasma pneumoniae Infection in Asthma. | 2012 | Allergy Asthma Immunol Res | pmid:22379599 |
| Kariyawasam HH and Scadding GK | Chronic rhinosinusitis: therapeutic efficacy of anti-inflammatory and antibiotic approaches. | 2011 | Allergy Asthma Immunol Res | pmid:21966602 |
| Damianos AJ and McGarrity TJ | Treatment strategies for Helicobacter pylori infection. | 1997 | Am Fam Physician | pmid:9191460 |
| Karlstadt RG and Walker K | Update on prescribing information for pantoprazole. | 2003 | Am Fam Physician | pmid:12674447 |
| Gregory DS | Pertussis: a disease affecting all ages. | 2006 | Am Fam Physician | pmid:16913160 |
| Chaisson R | Clarithromycin is effective against M. avium complex in AIDS. | 1992 | Am Fam Physician | pmid:1456199 |
| Elston D | Nontuberculous mycobacterial skin infections: recognition and management. | 2009 | Am J Clin Dermatol | pmid:19658440 |
| Rebora A | The management of rosacea. | 2002 | Am J Clin Dermatol | pmid:12180896 |
| Scheinfeld N | Confluent and reticulated papillomatosis : a review of the literature. | 2006 | Am J Clin Dermatol | pmid:17007541 |
| Zeegelaar JE and Faber WR | Imported tropical infectious ulcers in travelers. | 2008 | Am J Clin Dermatol | pmid:18572973 |
| Chang SL et al. | Bilateral sporotrichoid lymphocutaneous dermatosis in a drug abuser: case report and review of the literature. | 2008 | Am J Clin Dermatol | pmid:18973406 |
| Wedi B and Kapp A | Helicobacter pylori infection in skin diseases: a critical appraisal. | 2002 | Am J Clin Dermatol | pmid:12010072 |
| Curth HM et al. | Effects of Helicobacter pylori Eradication in Chronic Spontaneous Urticaria: Results from a Retrospective Cohort Study. | 2015 | Am J Clin Dermatol | pmid:26334425 |
| Parsad D et al. | A guide to selection and appropriate use of macrolides in skin infections. | 2003 | Am J Clin Dermatol | pmid:12762831 |
| Yeh I et al. | Cutaneous mycobacterial spindle cell pseudotumor: a potential mimic of soft tissue neoplasms. | 2011 | Am J Dermatopathol | pmid:21712686 |
| Song H et al. | Cutaneous nontuberculous mycobacterial infection: a clinicopathological study of 7 cases. | 2009 | Am J Dermatopathol | pmid:19384062 |
| Lai J et al. | Epithelioid histiocytic infiltrate caused by Mycobacterium scrofulaceum infection: a potential mimic of various neoplastic entities. | 2013 | Am J Dermatopathol | pmid:22935892 |
| Sketris IS et al. | Comparison of anti-infective drug use in elderly persons in Manitoba, Nova Scotia, and Saskatchewan, Canada: relationship to drug insurance reimbursement policies. | 2004 | Am J Geriatr Pharmacother | pmid:15555476 |
| Hsu O et al. | Decreased plasma efavirenz concentrations in a patient receiving rifabutin. | 2010 | Am J Health Syst Pharm | pmid:20852162 |
| Johnson TJ and Hedge DD | Esomeprazole: a clinical review. | 2002 | Am J Health Syst Pharm | pmid:12132559 |
| Halpern MT et al. | Cost-effectiveness of gemifloxacin: results from the GLOBE study. | 2002 | Am J Health Syst Pharm | pmid:12132563 |
| Chahine C et al. | Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori. | 2001 | Am J Health Syst Pharm | pmid:11596697 |
| Henneman A and Thornby KA | Risk of hypotension with concomitant use of calcium-channel blockers and macrolide antibiotics. | 2012 | Am J Health Syst Pharm | pmid:22644980 |
| Kaeser YA et al. | Severe hypotension and bradycardia associated with verapamil and clarithromycin. | 1998 | Am J Health Syst Pharm | pmid:9825040 |
| Three new studies expand understanding of MAC therapy. | 1996 | Am J Health Syst Pharm | pmid:8899122 | |
| Peloquin CA and Berning SE | Advice on treatment of Mycobacterium avium complex infection. | 1997 | Am J Health Syst Pharm | pmid:9161632 |
| H. pylori treatment recognized by FDA. | 1996 | Am J Health Syst Pharm | pmid:8725200 | |
| Sonnenberg A et al. | Antibiotic therapy of Helicobacter pylori infection reduces healthcare expenditures related to duodenal ulcer. | 1999 | Am J Manag Care | pmid:10345967 |
| Lilley LL and Guanci R | A dangerous combination. | 1998 | Am J Nurs | pmid:9612423 |
| Antibiotic gets FDA nod for MAC treatment. | 1994 | Am J Nurs | pmid:8304386 | |
| Evans AK and Cunningham MJ | Atypical mycobacterial cervicofacial lymphadenitis in children: a disease as old as mankind, yet a persistent challenge. | 2005 Sep-Oct | Am J Otolaryngol | pmid:16137534 |
| Hashisaki GT | Update on macrolide antibiotics. | 1995 May-Jun | Am J Otolaryngol | pmid:7661309 |
| Einarson A et al. | A prospective controlled multicentre study of clarithromycin in pregnancy. | 1998 | Am J Perinatol | pmid:9890248 |
| Jacoby EB and Porter KB | Helicobacter pylori infection and persistent hyperemesis gravidarum. | 1999 | Am J Perinatol | pmid:10355915 |
| Abouesh A and Hobbs WR | Clarithromycin-induced mania. | 1998 | Am J Psychiatry | pmid:9812131 |
| Brooks JO and Hoblyn JC | Secondary mania in older adults. | 2005 | Am J Psychiatry | pmid:16263839 |
| Keicho N and Kudoh S | Diffuse panbronchiolitis: role of macrolides in therapy. | 2002 | Am J Respir Med | pmid:14720066 |
| Darkes MJ and Perry CM | Clarithromycin extended-release tablet: a review of its use in the management of respiratory tract infections. | 2003 | Am J Respir Med | pmid:14720016 |
| Tohnai A et al. | Clarithromycin suppresses proliferation of rat nasal epithelium exposed to endotoxin. | 1998 Nov-Dec | Am J Rhinol | pmid:9883303 |
| Zeng M et al. | Comparison of efficacy of mometasone furoate versus clarithromycin in the treatment of chronic rhinosinusitis without nasal polyps in Chinese adults. | 2011 Nov-Dec | Am J Rhinol Allergy | pmid:22185725 |
| Gupta AK and Moorman CT | Nocardia nova infection after primary anterior cruciate ligament reconstruction with tibialis anterior allograft. | 2010 | Am J Sports Med | pmid:20375367 |
| Yang X et al. | Comparison Between Sequential Therapy and Modified Bismuth-Included Quadruple Therapy for Helicobacter pylori Eradication in Chinese Patients. | Am J Ther | pmid:25923229 | |
| Feng L et al. | Sequential Therapy or Standard Triple Therapy for Helicobacter pylori Infection: An Updated Systematic Review. | Am J Ther | pmid:25569598 | |
| McCarthy DM et al. | Impact of cotherapy with some proton pump inhibitors on medical claims among HMO patients already using other common drugs also cleared by cytochrome P450. | 2003 Sep-Oct | Am J Ther | pmid:12975717 |
| Chang NL et al. | Clarithromycin-Induced Torsades de Pointes. | Am J Ther | pmid:25057773 | |
| Kurowski K et al. | Clarithromycin-induced alterations in vaginal flora. | 2000 | Am J Ther | pmid:11317173 |
| Alkim H et al. | Role of Bismuth in the Eradication of Helicobacter pylori. | Am J Ther | pmid:26808355 | |
| Jacobson TA | Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors. | 2004 | Am. J. Cardiol. | pmid:15518608 |
| Hsu CH et al. | The lesson of supplementary treatment with Chinese medicine on severe laboratory-confirmed SARS patients. | 2006 | Am. J. Chin. Med. | pmid:17163582 |
| Wang YC et al. | In vitro activity of Impatiens balsamina L. against multiple antibiotic-resistant Helicobacter pylori. | 2009 | Am. J. Chin. Med. | pmid:19655409 |
| Sauter C and Blum S | Regression of lung lesions in Hodgkin's disease by antibiotics: case report and hypothesis on the etiology of Hodgkin's disease. | 2003 | Am. J. Clin. Oncol. | pmid:12576932 |
| Kapadia M et al. | Invasive Streptomyces infections: six cases and literature review. | 2007 | Am. J. Clin. Pathol. | pmid:17369139 |
| Buchanan Keller K and Lemberg L | Torsade. | 2008 | Am. J. Crit. Care | pmid:18158394 |
| Laine L et al. | Bismuth-based quadruple therapy using a single capsule of bismuth biskalcitrate, metronidazole, and tetracycline given with omeprazole versus omeprazole, amoxicillin, and clarithromycin for eradication of Helicobacter pylori in duodenal ulcer patients: a prospective, randomized, multicenter, North American trial. | 2003 | Am. J. Gastroenterol. | pmid:12650788 |
| al-Assi MT et al. | Clarithromycin, tetracycline, and bismuth: a new non-metronidazole therapy for Helicobacter pylori infection. | 1994 | Am. J. Gastroenterol. | pmid:8053435 |
| Ali' A et al. | A second-line anti-Helicobacter pylori therapy in patients with previously failed treatment. | 1999 | Am. J. Gastroenterol. | pmid:10445583 |
| Chiba N | Omeprazole and clarithromycin with and without metronidazole for the eradication of Helicobacter pylori. | 1996 | Am. J. Gastroenterol. | pmid:8855737 |
| Odaka T et al. | Evaluation of the Helicobacter pylori stool antigen test for monitoring eradication therapy. | 2002 | Am. J. Gastroenterol. | pmid:11922552 |
| Sirimontaporn N et al. | Ten-day sequential therapy of Helicobacter pylori infection in Thailand. | 2010 | Am. J. Gastroenterol. | pmid:20010919 |
| Basu PP et al. | A randomized study comparing levofloxacin, omeprazole, nitazoxanide, and doxycycline versus triple therapy for the eradication of Helicobacter pylori. | 2011 | Am. J. Gastroenterol. | pmid:21989146 |
| Hasegawa T et al. | Image of the month: Disseminated Nontuberculous Mycobacteriosis. | 2015 | Am. J. Gastroenterol. | pmid:26673493 |
| de Boer WA et al. | Optimal treatment of Helicobacter pylori with ranitidine bismuth citrate (RBC): a randomized comparison between two 7-day triple therapies and a 14-day dual therapy. | 1998 | Am. J. Gastroenterol. | pmid:9672338 |
| van der Wouden EJ et al. | One-week triple therapy with ranitidine bismuth citrate, clarithromycin and metronidazole versus two-week dual therapy with ranitidine bismuth citrate and clarithromycin for Helicobacter pylori infection: a randomized, clinical trial. | 1998 | Am. J. Gastroenterol. | pmid:9707042 |
| Chey WD et al. | ACG Clinical Guideline: Treatment of Helicobacter pylori Infection. | 2017 | Am. J. Gastroenterol. | pmid:28071659 |