clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Auw-Hädrich C et al. | [Clarithromycin for monotherapy of B-cell MALT lymphoma?]. | 2013 | Ophthalmologe | pmid:24231914 |
| Rezvanian E and Watson NF | Kleine-levin syndrome treated with clarithromycin. | 2013 | J Clin Sleep Med | pmid:24235906 |
| Cosme A et al. | Usefulness of antimicrobial susceptibility in the eradication of Helicobacter pylori. | 2013 | Clin. Microbiol. Infect. | pmid:22512623 |
| Srivastava S et al. | Therapeutic drug management: is it the future of multidrug-resistant tuberculosis treatment? | 2013 | Eur. Respir. J. | pmid:24293417 |
| Gui J et al. | [Drug sensitivity analysis of Mycobacterium chelonae and Mycobacterium abscessus and evaluation of Etest for susceptibility testing]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24252731 |
| Berghaus LJ et al. | Mutant prevention concentration and mutant selection window for 10 antimicrobial agents against Rhodococcus equi. | 2013 | Vet. Microbiol. | pmid:23915992 |
| Pedersen JM et al. | Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). | 2013 | Toxicol. Sci. | pmid:24014644 |
| Chen K et al. | Low dose macrolide administration for long term is effective for otitis media with effusion in children. | 2013 | Auris Nasus Larynx | pmid:22673738 |
| Drago F et al. | Acute autoimmune thrombocytopenia and worsening of dermatomyositis after administration of clarithromycin. | 2013 | J. Am. Acad. Dermatol. | pmid:24124859 |
| Herath SC and Poole P | Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). | 2013 | Cochrane Database Syst Rev | pmid:24288145 |
| Zhu D et al. | Synthesis of 4″-O-desosaminyl clarithromycin derivatives and their anti-bacterial activities. | 2013 | Bioorg. Med. Chem. Lett. | pmid:24139585 |
| Nasa M et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a randomized study. | 2013 | Indian J Gastroenterol | pmid:24158898 |
| Kim SY et al. | Comparative study of Helicobacter pylori eradication rates with 5-day quadruple "concomitant" therapy and 7-day standard triple therapy. | 2013 | J. Clin. Gastroenterol. | pmid:22647826 |
| Fagoonee S et al. | Efficacy of cefixime-based triple therapy for Helicobacter pylori eradication: a retrospective study. | 2013 | Panminerva Med | pmid:24088806 |
| Gisbert JP et al. | Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients. | 2013 | J. Clin. Gastroenterol. | pmid:22647827 |
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| Schafranek L et al. | Clarithromycin enhances dasatinib-induced cell death in chronic myeloid leukemia cells, by inhibition of late stage autophagy. | 2013 | Leuk. Lymphoma | pmid:22656271 |
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| Megraud F et al. | Helicobacter pylori resistance to antibiotics in Europe and its relationship to antibiotic consumption. | 2013 | Gut | pmid:22580412 |
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| Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
| Morse AL et al. | A randomized controlled trial comparing sequential with triple therapy for Helicobacter pylori in an Aboriginal community in the Canadian North. | 2013 | Can. J. Gastroenterol. | pmid:24340314 |
| Pan W et al. | Effects of clopidogrel and clarithromycin on the disposition of sibutramine and its active metabolites M1 and M2 in relation to CYP2B6*6 polymorphism. | 2013 | Xenobiotica | pmid:22830954 |
| Avci O et al. | A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. | 2013 | J Dermatolog Treat | pmid:21923567 |
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| Otsuka SH | Severe hypoglycemia from Helicobacter pylori triple-drug therapy and insulin detemir drug interaction. | 2013 | Pharmacotherapy | pmid:23471710 |
| Jiang JW et al. | Synthesis and antibacterial evaluation of a novel series of 10-hydroxyl ketolide derivatives. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23591116 |
| Odagiri T et al. | Design, synthesis, and biological evaluations of novel 7-[7-amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-8-methoxyquinolines with potent antibacterial activity against respiratory pathogens. | 2013 | J. Med. Chem. | pmid:23409972 |
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| Sasaki H et al. | Ten-year trend of the cumulative Helicobacter pylori eradication rate for the 'Japanese eradication strategy'. | 2013 | Digestion | pmid:24356705 |
| Yakoob J et al. | Low rate of recurrence of Helicobacter pylori infection in spite of high clarithromycin resistance in Pakistan. | 2013 | BMC Gastroenterol | pmid:23433429 |
| Yuan Y et al. | Optimum duration of regimens for Helicobacter pylori eradication. | 2013 | Cochrane Database Syst Rev | pmid:24338763 |
| Amin M et al. | Anti-Helicobacter pylori and urease inhibition activities of some traditional medicinal plants. | 2013 | Molecules | pmid:23434867 |
| Ogata SK et al. | High Helicobacter pylori resistance to metronidazole and clarithromycin in Brazilian children and adolescents. | 2013 | J. Pediatr. Gastroenterol. Nutr. | pmid:23403439 |
| Morgan DR et al. | Risk of recurrent Helicobacter pylori infection 1 year after initial eradication therapy in 7 Latin American communities. | 2013 | JAMA | pmid:23403682 |
| Shallom SJ et al. | New rapid scheme for distinguishing the subspecies of the Mycobacterium abscessus group and identifying Mycobacterium massiliense isolates with inducible clarithromycin resistance. | 2013 | J. Clin. Microbiol. | pmid:23804391 |
| Greupink R et al. | Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions. | 2013 | Eur J Pharm Sci | pmid:23806476 |
| Lee G et al. | Nodular bronchiectatic Mycobacterium avium complex pulmonary disease. Natural course on serial computed tomographic scans. | 2013 | Ann Am Thorac Soc | pmid:23952847 |
| Park CW et al. | Advanced spray-dried design, physicochemical characterization, and aerosol dispersion performance of vancomycin and clarithromycin multifunctional controlled release particles for targeted respiratory delivery as dry powder inhalation aerosols. | 2013 | Int J Pharm | pmid:23820131 |
| Yu Q et al. | Treatment of pulmonary mucosa-associated lymphoid tissue lymphoma with clarithromycin. | 2013 | Chin. Med. J. | pmid:23786961 |
| Dabirmoghaddam P et al. | The efficacy of clarithromycin in patients with severe nasal polyposis. | 2013 | Acta Med Iran | pmid:23852839 |
| Chen PR and Tan SY | [The treatment outcomes of 21 cases of rapidly growing mycobacteria related pulmonary disease]. | 2013 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:23856140 |
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| Kate V et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a systematic review of recent evidence. | 2013 | Drugs | pmid:23625272 |
| Kato H et al. | Addition of clarithromycin to lenalidomide/low-dose dexamethasone was effective in a case of relapsed myeloma after long-term use of lenalidomide. | 2013 | Ann. Hematol. | pmid:23625297 |
| Bolhuis MS et al. | Clinical validation of the analysis of linezolid and clarithromycin in oral fluid of patients with multidrug-resistant tuberculosis. | 2013 | Antimicrob. Agents Chemother. | pmid:23689722 |
| Seddik H et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: a prospective randomized study. | 2013 | Eur. J. Clin. Pharmacol. | pmid:23695545 |
| Liang JH et al. | Synthesis, antibacterial activity and docking of 14-membered 9-O-(3-arylalkyl) oxime 11,12-cyclic carbonate ketolides. | 2013 | Eur J Med Chem | pmid:23202851 |
| Togami K et al. | Subcellular distribution of azithromycin and clarithromycin in rat alveolar macrophages (NR8383) in vitro. | 2013 | Biol. Pharm. Bull. | pmid:23995662 |
| Delavenne X et al. | A semi-mechanistic absorption model to evaluate drug-drug interaction with dabigatran: application with clarithromycin. | 2013 | Br J Clin Pharmacol | pmid:23210726 |
| Duman DG et al. | Saccharomyces boulardii ameliorates clarithromycin- and methotrexate-induced intestinal and hepatic injury in rats. | 2013 | Br. J. Nutr. | pmid:23279717 |
| Bessa LJ et al. | Helicobacter pylori free-living and biofilm modes of growth: behavior in response to different culture media. | 2013 | APMIS | pmid:23237527 |
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| Kute VB et al. | Bronchiolitis obliterans organizing pneumonia (BOOP) after renal transplantation. | 2013 | Int Urol Nephrol | pmid:22547135 |
| Vu DH et al. | Troubleshooting carry-over of LC-MS/MS method for rifampicin, clarithromycin and metabolites in human plasma. | 2013 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:23353809 |
| Kim SG et al. | Helicobacter pylori eradication on iatrogenic ulcer by endoscopic resection of gastric tumour: a prospective, randomized, placebo-controlled multi-centre trial. | 2013 | Dig Liver Dis | pmid:23333104 |
| Lim JH et al. | Clinical outcomes of two-week sequential and concomitant therapies for Helicobacter pylori eradication: a randomized pilot study. | 2013 | Helicobacter | pmid:23305083 |
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| Huang CW et al. | Synergistic activities of tigecycline with clarithromycin or amikacin against rapidly growing mycobacteria in Taiwan. | 2013 | Int. J. Antimicrob. Agents | pmid:23312605 |
| Thomas M et al. | Periprosthetic atypical mycobacterial infection in breast implants: a new kid on the block! | 2013 | J Plast Reconstr Aesthet Surg | pmid:23122691 |
| Pandey SK et al. | Antimalarial interaction of quinine and quinidine with clarithromycin. | 2013 | Parasitology | pmid:23137860 |
| Lahbabi M et al. | Sequential therapy versus standard triple-drug therapy for Helicobacter pylori eradication: result of the HPFEZ randomised study. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23168228 |
| Darwish KM et al. | RP-HPLC/pre-column derivatization for analysis of omeprazole, tinidazole, doxycycline and clarithromycin. | 2013 | J Chromatogr Sci | pmid:23081968 |
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| Lin KJ et al. | Safety of macrolides during pregnancy. | 2013 | Am. J. Obstet. Gynecol. | pmid:23254249 |
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| Matsumoto T et al. | Education and imaging. Gastrointestinal: colonic mucosa-associated lymphoid tissue lymphoma regressed by levofloxacin. | 2013 | J. Gastroenterol. Hepatol. | pmid:23527757 |
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| Pilcer G et al. | New co-spray-dried tobramycin nanoparticles-clarithromycin inhaled powder systems for lung infection therapy in cystic fibrosis patients. | 2013 | J Pharm Sci | pmid:23568616 |
| Feng Z et al. | Dissociative disorder induced by clarithromycin combined with rabeprazole in a patient with gastritis. | 2013 | J. Int. Med. Res. | pmid:23569151 |
| Gokmen T et al. | Clarithromycin treatment in preterm infants: a pilot study for prevention of feeding intolerance. | 2013 | J. Matern. Fetal. Neonatal. Med. | pmid:23570248 |
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| Gandhi S et al. | Calcium-channel blocker-clarithromycin drug interactions and acute kidney injury. | 2013 | JAMA | pmid:24346990 |
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