clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Petersen AM et al. | [Resistance of Helicobacter pylori to clarithomycin]. | 1998 | Ugeskr. Laeg. | pmid:9627511 |
| Archimandritis A et al. | Clostridium difficile colitis associated with a 'triple' regimen, containing clarithromycin and metronidazole, to eradicate Helicobacter pylori. | 1998 | J. Intern. Med. | pmid:9627163 |
| Roussel G and Igual J | Clarithromycin with minocycline and clofazimine for Mycobacterium avium intracellulare complex lung disease in patients without the acquired immune deficiency syndrome. GETIM. Groupe d'Etude et de Traitement des Infections à Mycobactéries. | 1998 | Int. J. Tuberc. Lung Dis. | pmid:9626603 |
| Tsuneoka H et al. | [Sensitivity of Helicobacter pylori to amoxicillin and clarythromycin with special reference to eradication therapy]. | 1998 | Kansenshogaku Zasshi | pmid:9621560 |
| Kruppa A et al. | Immediate reaction to roxithromycin and prick test cross-sensitization to erythromycin and clarithromycin. | 1998 | Dermatology (Basel) | pmid:9621142 |
| Torresani C | Clarithromycin: a new perspective in rosacea treatment. | 1998 | Int. J. Dermatol. | pmid:9620480 |
| Fischer BP et al. | [Tsutsugamushi fever. Rare rickettsiosis after a stay in the Philippines]. | 1998 | Dtsch. Med. Wochenschr. | pmid:9615696 |
| Lilley LL and Guanci R | A dangerous combination. | 1998 | Am J Nurs | pmid:9612423 |
| Ramon PM et al. | [Uveitis, arthralgia and pseudo-jaundice in a HIV seronegative patient due to rifabutin]. | 1998 | Rev Mal Respir | pmid:9608993 |
| Gavura SR and Nusinowitz S | Leukocytoclastic vasculitis associated with clarithromycin. | 1998 | Ann Pharmacother | pmid:9606474 |
| Moayyedi P et al. | Relevance of antibiotic sensitivities in predicting failure of omeprazole, clarithromycin, and tinidazole to eradicate Helicobacter pylori. | 1998 | J. Gastroenterol. | pmid:9605943 |
| Doherty TM and Sher A | IL-12 promotes drug-induced clearance of Mycobacterium avium infection in mice. | 1998 | J. Immunol. | pmid:9605144 |
| Harris A | Current regimens for treatment of Helicobacter pylori infection. | 1998 | Br. Med. Bull. | pmid:9604443 |
| Fujita K et al. | [Neutrophil count and IL-8 level of nasal secretion of patients with chronic paranasal sinusitis and the effects of macrolide antibiotics]. | 1998 | Jpn J Antibiot | pmid:9597505 |
| Miyamoto N et al. | [Test to set dosages for long-term administration of clarithromycin to treat chronic paranasal sinusitis]. | 1998 | Jpn J Antibiot | pmid:9597498 |
| Sasa K et al. | [Antineoplastic therapeutic effect of clarithromycin in rats]. | 1998 | Jpn J Antibiot | pmid:9597492 |
| Yano S et al. | [Significance of therapeutic efficacy of clarithromycin in a model for human lung cancer metastasis and a mouse tumor system]. | 1998 | Jpn J Antibiot | pmid:9597491 |
| Kokubo Y et al. | [Effect of clarithromycin on experimental pulmonary metastasis]. | 1998 | Jpn J Antibiot | pmid:9597488 |
| Ueta K et al. | [Evaluation of BRM (biological response modifier) action of clarithromycin (CAM)--effect on cytokine expression in a mouse lung cancer model]. | 1998 | Jpn J Antibiot | pmid:9597487 |
| Teramoto S et al. | [Effect of clarithromycin administration on interferon-gamma and interleukin 12 mRNA expression in the tumor tissue of non-small-cell lung cancer]. | 1998 | Jpn J Antibiot | pmid:9597486 |