clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (5)
- Drug Metab. Dispos. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (5)
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gysel M et al. | Torsades de pointes following clarithromycin treatment. | 2013 | Expert Rev Cardiovasc Ther | pmid:24147515 |
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| Jiang JW et al. | Synthesis and antibacterial evaluation of a novel series of 10-hydroxyl ketolide derivatives. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23591116 |
| Odagiri T et al. | Design, synthesis, and biological evaluations of novel 7-[7-amino-7-methyl-5-azaspiro[2.4]heptan-5-yl]-8-methoxyquinolines with potent antibacterial activity against respiratory pathogens. | 2013 | J. Med. Chem. | pmid:23409972 |
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| Bessa LJ et al. | Helicobacter pylori free-living and biofilm modes of growth: behavior in response to different culture media. | 2013 | APMIS | pmid:23237527 |
| Qvist T et al. | First report of lung transplantation in a patient with active pulmonary Mycobacterium simiae infection. | 2013 | Transplant. Proc. | pmid:23267789 |
| Secka O et al. | Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa. | 2013 | Antimicrob. Agents Chemother. | pmid:23263004 |
| Mueck W et al. | Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. | 2013 | Br J Clin Pharmacol | pmid:23305158 |
| Joosten M et al. | Case report: Helicobacter suis infection in a pig veterinarian. | 2013 | Helicobacter | pmid:23551953 |
| Unai S et al. | Sternal wound infection caused by Mycobacterium chelonae. | 2013 | J Card Surg | pmid:23941599 |
| Faraji F et al. | The effect of Helicobacter pylori eradication on migraine: a randomized, double blind, controlled trial. | 2012 Nov-Dec | Pain Physician | pmid:23159967 |
| Eremenko AA et al. | [Effect of clarithromycin on the systemic inflammatory response syndrome severity in patients after myocardial revascularization surgery]. | 2012 May-Jun | Anesteziol Reanimatol | pmid:22993930 |
| Singh V et al. | Vesicular palmoplantar pityriasis rosea. | 2012 Mar-Apr | Skinmed | pmid:22545332 |
| Gutiérrez-Castrellón P et al. | Efficacy and safety of clarithromycin in pediatric patients with upper respiratory infections: a systematic review with meta-analysis. | 2012 Mar-Apr | Rev. Invest. Clin. | pmid:22991774 |
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| Dhillon GS et al. | Clarithromycin for prevention of bronchiolitis obliterans syndrome in lung allograft recipients. | 2012 Jan-Feb | Clin Transplant | pmid:21352378 |
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| Hegazy SK et al. | Effect of clarithromycin and fluconazole on the pharmacokinetics of montelukast in human volunteers. | 2012 | Eur. J. Clin. Pharmacol. | pmid:22392555 |
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| Sezikli M et al. | Supplementing vitamins C and E to standard triple therapy for the eradication of Helicobacter pylori. | 2012 | J Clin Pharm Ther | pmid:21740452 |
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| Kwan BY and Rabheru K | Manic episode associated with clarithromycin in a patient with medically treated depression. | 2012 | Prim Care Companion CNS Disord | pmid:22943025 |
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