clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Adamek RJ et al. | Primary and acquired Helicobacter pylori resistance to clarithromycin, metronidazole, and amoxicillin--influence on treatment outcome. | 1998 | Am. J. Gastroenterol. | pmid:9517645 |
Bardhan KD et al. | Ranitidine bismuth citrate with clarithromycin given twice daily effectively eradicates Helicobacter pylori and heals duodenal ulcers. | 1998 | Am. J. Gastroenterol. | pmid:9517644 |
Williamson R et al. | New options in Helicobacter pylori eradication: efficacy, resistance and synergy. | 1998 | Scand. J. Gastroenterol. Suppl. | pmid:9515751 |
Moayyedi P | Amoxycillin dual therapy against Helicobacter pylori--the final nail in the coffin? | 1997 | Ital J Gastroenterol Hepatol | pmid:9513823 |
Sato K et al. | Antimicrobial activities of benzoxazinorifamycin KRM-1648, clarithromycin and levofloxacin against intracellular Mycobacterium avium complex phagocytosed by murine peritoneal macrophages. | 1998 | J. Antimicrob. Chemother. | pmid:9511040 |
Carlson LD et al. | Standardized BACTEC method to measure clarithromycin susceptibility of Mycobacterium genavense. | 1998 | J. Clin. Microbiol. | pmid:9508306 |
Rosina P et al. | Fixed drug eruption from clarithromycin. | 1998 | Contact Derm. | pmid:9506224 |
Ziering W and McElvaine P | Randomized comparison of once-daily ceftibuten and twice-daily clarithromycin in the treatment of acute exacerbation of chronic bronchitis. | 1998 Jan-Feb | Infection | pmid:9505188 |
Hocqueloux L et al. | Pulmonary Mycobacterium avium complex disease without dissemination in HIV-infected patients. | 1998 | Chest | pmid:9498982 |
Dubois A et al. | Cure of Helicobacter pylori infection by omeprazole-clarithromycin-based therapy in non-human primates. | 1998 | J. Gastroenterol. | pmid:9497216 |
Kusuhara H et al. | Evaluation of combined antibiotic-omeprazole therapies in Helicobacter pylori-infected Mongolian gerbils. | 1998 | J. Gastroenterol. | pmid:9497215 |
Payen MC et al. | [Manifestations, diagnosis and treatment of non-tuberculous mycobacterial infections in patients with HIV infection]. | 1997 | Rev Mal Respir | pmid:9496599 |
Pérez Mota A et al. | Helicobacter pylori, efficacy of the new triple therapy in six and twelve-day schedules. | 1997 | Rev Esp Enferm Dig | pmid:9494375 |
Boixeda de Miquel D | [Efficacy of the triple therapy in the eradication of H. pylori in peptic ulcer]. | 1997 | Rev Esp Enferm Dig | pmid:9494374 |
Kondoh K and Hashiba M | [Inhibitory effect of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. | 1998 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9493436 |
Hermon-Taylor J et al. | Mycobacterium paratuberculosis cervical lymphadenitis, followed five years later by terminal ileitis similar to Crohn's disease. | 1998 | BMJ | pmid:9492675 |
Igea JM and Lázaro M | Hypersensitivity reaction to clarithromycin. | 1998 | Allergy | pmid:9491242 |
Ridgway GL et al. | The in-vitro activity of grepafloxacin against Chlamydia spp., Mycoplasma spp., Ureaplasma urealyticum and Legionella spp. | 1997 | J. Antimicrob. Chemother. | pmid:9484871 |
Hotz J | [Reflux disease of the gastrointestinal tract. Acute therapy and long-term care in daily practice. 2. Therapeutic procedure--diagnosis--therapy-diagram]. | 1997 | Fortschr. Med. | pmid:9480263 |
Cammarota G et al. | Regression of a primary gastric MALT lymphoma with extensive antrum lesions by Helicobacter pylori eradication. | 1997 | Ital J Gastroenterol Hepatol | pmid:9476192 |