clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with clarithromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nagore E et al. | Cutaneous infection with Mycobacterium fortuitum after localized microinjections (mesotherapy) treated successfully with a triple drug regimen. | 2001 Aug-Sep | Acta Derm. Venereol. | pmid:11720180 |
Woznicová V et al. | Clarithromycin treatment failure due to macrolide resistance in Treponema pallidum in a patient with primary syphilis. | 2010 | Acta Derm. Venereol. | pmid:20169316 |
Valsecchi R and Pigatto P | Chronic urticaria and Helicobacter pylori. | 1998 | Acta Derm. Venereol. | pmid:9833044 |
Chung WK et al. | Cutaneous Mycobacterium chelonae infection presenting as symmetrical plaques on both shins in an immunocompetent patient. | 2009 | Acta Derm. Venereol. | pmid:19997711 |
Pranteda G et al. | Vegetating iododerma and pulmonary eosinophilic infiltration. A simple co-occurrence? | 2004 | Acta Derm. Venereol. | pmid:15844644 |
Ezzedine K et al. | Painful Buruli ulcer in a Malian visitor to France. | 2010 | Acta Derm. Venereol. | pmid:20574617 |
Belić M et al. | Sporotrichoid presentation of Mycobacterium marinum infection of the upper extremity. A case report. | 2006 | Acta Dermatovenerol Alp Pannonica Adriat | pmid:17053849 |
De Punzio C et al. | Isolation of Chlamydia trachomatis during IVF-ET. | 1991 Jul-Aug | Acta Eur. Fertil. | pmid:1844324 |
Kaboli SA et al. | Effect of addition of vitamin C to clarithromycin-amoxicillin-omeprazol triple regimen on Helicobacter pylori eradication. | 2009 Apr-Jun | Acta Gastroenterol. Belg. | pmid:19637777 |
Aguemon B et al. | Primary antibiotic resistance and effectiveness of Helicobacter pylori triple therapy in ulcero-inflammatory pathologies of the upper digestive tract. | 2005 Jul-Sep | Acta Gastroenterol. Belg. | pmid:16268413 |
Karatapanis S et al. | "7, 10 and 14-days rabeprazole-based standard triple therapies for H. pylori eradication: are they still effective? A randomized trial". | 2011 | Acta Gastroenterol. Belg. | pmid:22103045 |
Konturek PC et al. | Gastric MALT-lymphoma, gastrin and cyclooxygenases. | 2002 Jan-Mar | Acta Gastroenterol. Belg. | pmid:12014312 |
Gonzalez Cueto D et al. | [Gastric solitary plasmacytoma associated with +Helicobacter pylori infection]. | 1999 | Acta Gastroenterol. Latinoam. | pmid:10533659 |
Ramirez Mayans JA et al. | [Elimination of Helicobacter pylori in patients with recurrent abdominal pain with simultaneous administration of ranitidine, bismuth subsalicylate and clarithromycin]. | 1996 | Acta Gastroenterol. Latinoam. | pmid:9363265 |
Améndola R et al. | [Is dental plaque a normal Helicobacter pylori reservoir?]. | 1998 | Acta Gastroenterol. Latinoam. | pmid:9713656 |
Sayan O et al. | The Efficacy of Helicobacter pylori eradication in the treatment of idiopathic thrombocytopenic purpura--the first study in Turkey. | 2006 | Acta Haematol. | pmid:16914913 |
Mark TM and Coleman M | It's Time to Take Clarithromycin Seriously in Multiple Myeloma. | 2016 | Acta Haematol. | pmid:26505907 |
Qiu XH et al. | Clarithromycin Synergistically Enhances Thalidomide Cytotoxicity in Myeloma Cells. | 2016 | Acta Haematol. | pmid:26505646 |
Holmberg LA et al. | Results from Two Consecutive Studies of Consolidation Therapy after Autologous Transplant for Multiple Myeloma: Thalidomide, Dexamethasone, and Clarithromycin or Lenalidomide, Dexamethasone, and Clarithromycin. | 2017 | Acta Haematol. | pmid:28355602 |
Decazes JM | [What shall we make of the arrival of "generalized" antibiotics to anti-Hansen's therapy?]. | 2001-2002 | Acta Leprol | pmid:12136737 |