clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- J. Antimicrob. Chemother. (1)
- Clin. Diagn. Lab. Immunol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fan Y et al. | High and low doses of clarithromycin treatment are associated with different clinical efficacies and immunomodulatory properties in chronic rhinosinusitis. | 2014 | J Laryngol Otol | pmid:24555753 |
| Hanson KE et al. | Rapid molecular detection of inducible macrolide resistance in Mycobacterium chelonae and M. abscessus strains: a replacement for 14-day susceptibility testing? | 2014 | J. Clin. Microbiol. | pmid:24554745 |
| Almeida N et al. | Triple therapy with high-dose proton-pump inhibitor, amoxicillin, and doxycycline is useless for Helicobacter pylori eradication: a proof-of-concept study. | 2014 | Helicobacter | pmid:24506175 |
| Lara-MartÃn PA et al. | Occurrence, distribution and partitioning of nonionic surfactants and pharmaceuticals in the urbanized Long Island Sound Estuary (NY). | 2014 | Mar. Pollut. Bull. | pmid:24467856 |
| Markert C et al. | Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers. | 2014 | Br J Clin Pharmacol | pmid:23738582 |
| Furuta T et al. | Effect of dosing schemes of amoxicillin on eradication rates of Helicobacter pylori with amoxicillin-based triple therapy. | 2014 | J Clin Pharmacol | pmid:24122836 |
| Ratzinger F et al. | Azithromycin suppresses CD4(+) T-cell activation by direct modulation of mTOR activity. | 2014 | Sci Rep | pmid:25500904 |
| Trotti LM et al. | Improvement in daytime sleepiness with clarithromycin in patients with GABA-related hypersomnia: Clinical experience. | 2014 | J. Psychopharmacol. (Oxford) | pmid:24306133 |
| Nie W et al. | [The analysis of species identification and susceptibility testing of Mycobacterium abscessus]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262693 |
| Iwanaga K and Carter ER | Mycobacterium abscessus complex lung infection in a toddler with a tracheostomy. | 2014 | Pediatr. Pulmonol. | pmid:23460506 |
| Campanale M et al. | Nickel free-diet enhances the Helicobacter pylori eradication rate: a pilot study. | 2014 | Dig. Dis. Sci. | pmid:24595654 |
| Schuhfried G et al. | Gilles de la Tourette Syndrome caused by Mycoplasma pneumoniae successfully treated with macrolides. | 2014 | Klin Padiatr | pmid:25153913 |
| Svanström H et al. | Use of clarithromycin and roxithromycin and risk of cardiac death: cohort study. | 2014 | BMJ | pmid:25139799 |
| Giamarellos-Bourboulis EJ et al. | Effect of clarithromycin in patients with suspected Gram-negative sepsis: results of a randomized controlled trial. | 2014 | J. Antimicrob. Chemother. | pmid:24292991 |
| Zhao Y and Hu ZY | Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate. | 2014 | Br. J. Pharmacol. | pmid:24283665 |
| Harvey E and Varatharaj A | Round pneumonia. | 2014 | QJM | pmid:23708793 |
| Oztürk K et al. | Diagnosis of helicobacter pylori infection. | 2014 | Turk J Gastroenterol | pmid:25141328 |
| Lee SH et al. | The drug resistance profile of Mycobacterium abscessus group strains from Korea. | 2014 | Ann Lab Med | pmid:24422193 |
| Pathak V et al. | Macrolide use leads to clinical and radiological improvement in patients with cryptogenic organizing pneumonia. | 2014 | Ann Am Thorac Soc | pmid:24460438 |
| Jesus FP et al. | In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum. | 2014 | Antimicrob. Agents Chemother. | pmid:25001300 |
| Wu JY et al. | Evidence-based recommendations for successful Helicobacter pylori treatment. | 2014 | Expert Rev Gastroenterol Hepatol | pmid:24410470 |
| Sugamata R et al. | Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. | 2014 | J. Antibiot. | pmid:24496145 |
| DÃaz Cuevas Z et al. | [Nodular skin lesions in a patient with rheumatoid arthritis under therapy with anti-tumor necrosis factor-α]. | 2014 | Med Clin (Barc) | pmid:23877097 |
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| Ke AB et al. | Itraconazole and clarithromycin as ketoconazole alternatives for clinical CYP3A inhibition studies. | 2014 | Clin. Pharmacol. Ther. | pmid:24747234 |
| Ghosh N et al. | Clarithromycin overcomes resistance to lenalidomide and dexamethasone in multiple myeloma. | 2014 | Am. J. Hematol. | pmid:24723438 |
| Maurer FP et al. | Erm(41)-dependent inducible resistance to azithromycin and clarithromycin in clinical isolates of Mycobacterium abscessus. | 2014 | J. Antimicrob. Chemother. | pmid:24500188 |
| Tranos P et al. | Bilateral diffuse iris atrophy after the use of oral clarithromycin. | 2014 | Cutan Ocul Toxicol | pmid:23763291 |
| Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
| Page SR and Yee KC | Rhabdomyolysis in association with simvastatin and dosage increment in clarithromycin. | 2014 | Intern Med J | pmid:25041770 |
| Phillips RO et al. | Clinical and bacteriological efficacy of rifampin-streptomycin combination for two weeks followed by rifampin and clarithromycin for six weeks for treatment of Mycobacterium ulcerans disease. | 2014 | Antimicrob. Agents Chemother. | pmid:24323473 |
| McNicholl AG et al. | Randomised clinical trial comparing sequential and concomitant therapies for Helicobacter pylori eradication in routine clinical practice. | 2014 | Gut | pmid:23665990 |
| Karamanolis GP et al. | The evolution of Helicobacter pylori antibiotics resistance over 10 years in Greece. | 2014 | Digestion | pmid:25531953 |
| Hemphill A et al. | Treatment of echinococcosis: albendazole and mebendazole--what else? | 2014 | Parasite | pmid:25526545 |
| Kawai T et al. | Changes in the first line Helicobacter pylori eradication rates using the triple therapy-a multicenter study in the Tokyo metropolitan area (Tokyo Helicobacter pylori study group). | 2014 | J. Gastroenterol. Hepatol. | pmid:25521730 |
| Srinarong C et al. | Improved eradication rate of standard triple therapy by adding bismuth and probiotic supplement for Helicobacter pylori treatment in Thailand. | 2014 | Asian Pac. J. Cancer Prev. | pmid:25520127 |
| Wang B et al. | Standard triple therapy for Helicobacter pylori infection in China: a meta-analysis. | 2014 | World J. Gastroenterol. | pmid:25356059 |
| Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
| Homma S et al. | The successful management of respiratory complications with long-term, low-dose macrolide administration in pediatric heart transplant recipients. | 2014 | Int Heart J | pmid:25297501 |
| Renvoisé A et al. | Significant difference in drug susceptibility distribution between Mycobacterium avium and Mycobacterium intracellulare. | 2014 | J. Clin. Microbiol. | pmid:25274991 |
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| Malfertheiner P and Selgrad M | Helicobacter pylori. | 2014 | Curr. Opin. Gastroenterol. | pmid:25268839 |
| Ito Y et al. | The influence of environmental exposure on the response to antimicrobial treatment in pulmonary Mycobacterial avium complex disease. | 2014 | BMC Infect. Dis. | pmid:25266993 |
| de Miguel-Martinez I et al. | [Bacteriemia due to Mycobacterium canariasense in an oncohematological patient with a long-term central device]. | 2014 | Enferm. Infecc. Microbiol. Clin. | pmid:25262854 |
| Gui J et al. | [Subspecies identification for Mycobacterium abscessus group]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:25262692 |
| Higgins JW et al. | Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1. | 2014 | Drug Metab. Dispos. | pmid:25106415 |
| Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
| Nilsson MF and Webster WS | Effects of macrolide antibiotics on rat embryonic heart function in vitro. | 2014 | Birth Defects Res. B Dev. Reprod. Toxicol. | pmid:24753334 |
| Peng YC et al. | Clarithromycin modulates Helicobacter pylori-induced activation of nuclear factor-κB through classical and alternative pathways in gastric epithelial cells. | 2014 | Clin. Exp. Med. | pmid:23129507 |
| Kutluk G et al. | Sequential therapy versus standard triple therapy for Helicobacter pylori eradication in children: any advantage in clarithromycin-resistant strains? | 2014 | Eur J Gastroenterol Hepatol | pmid:25171023 |
| Higashi F et al. | Additional treatment with clarithromycin reduces fever duration in patients with influenza. | 2014 | Respir Investig | pmid:25169846 |
| de Boer EM et al. | [Antibiotic resistance of Helicobacter pylori: prevalence in one region in the southern Netherlands and implications for treatment]. | 2014 | Ned Tijdschr Geneeskd | pmid:25159698 |
| Wallace RJ et al. | Macrolide/Azalide therapy for nodular/bronchiectatic mycobacterium avium complex lung disease. | 2014 | Chest | pmid:24457542 |
| Molina-Infante J and Gisbert JP | Optimizing clarithromycin-containing therapy for Helicobacter pylori in the era of antibiotic resistance. | 2014 | World J. Gastroenterol. | pmid:25132750 |
| Heo J et al. | A randomised clinical trial of 10-day concomitant therapy and standard triple therapy for Helicobacter pylori eradication. | 2014 | Dig Liver Dis | pmid:25132282 |
| Lebedeva MV et al. | Clarithromycin as a chiral selector for enantioseparation of basic compounds in nonaqueous capillary electrophoresis. | 2014 | Electrophoresis | pmid:25100556 |
| Katayama M et al. | Preliminary study of interaction of clarithromycin with tacrolimus in cats. | 2014 | J. Vet. Med. Sci. | pmid:25099737 |
| Teh X et al. | Functional and molecular surveillance of Helicobacter pylori antibiotic resistance in Kuala Lumpur. | 2014 | PLoS ONE | pmid:25003707 |
| Lyons J et al. | An unusual lung mass post stem cell transplantation. | 2014 | Transpl Infect Dis | pmid:24995624 |
| Lee JW et al. | A comparison between 15-day sequential, 10-day sequential and proton pump inhibitor-based triple therapy for Helicobacter pylori infection in Korea. | 2014 | Scand. J. Gastroenterol. | pmid:24988873 |
| Rakici H et al. | Comparison of standard triple therapy, sequential therapy and moxifloxacin-based triple therapy for Helicobacter pylori infection: Patients' compliance and bacterial eradication rates. | 2014 | J Dig Dis | pmid:24980811 |
| Acosta CP et al. | [Determination of single nucleotide mutations in the 23S rRNA gene of Helicobacter pylori related to clarithromycin resistance in a population from Cauca, Colombia]. | 2014 | Biomedica | pmid:24968047 |
| Lee JW et al. | GenoType HelicoDR test in the determination of antimicrobial resistance of Helicobacter pylori in Korea. | 2014 | Scand. J. Gastroenterol. | pmid:24957849 |
| Raffaldi I et al. | An atypical deep neck infection in a two-year-old child. | 2014 | Infez Med | pmid:24955801 |
| Oh DH et al. | Efficacy of hybrid therapy as first-line regimen for Helicobacter pylori infection compared with sequential therapy. | 2014 | J. Gastroenterol. Hepatol. | pmid:24955448 |
| Patel K et al. | Oral delivery of paclitaxel nanocrystal (PNC) with a dual Pgp-CYP3A4 inhibitor: preparation, characterization and antitumor activity. | 2014 | Int J Pharm | pmid:24954663 |
| Vafaeimanesh J et al. | Expression comparison of azithromycin and clarithromycin in triple-therapy regimens for eradication of Helicobacter pylori in hemodialysis patients. | 2014 | Saudi J Kidney Dis Transpl | pmid:24434382 |
| Bonferoni MC et al. | Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid. | 2014 | Eur J Pharm Biopharm | pmid:24384070 |
| Liu CP et al. | NO-releasing xanthine KMUP-1 bonded by simvastatin attenuates bleomycin-induced lung inflammation and delayed fibrosis. | 2014 | Pulm Pharmacol Ther | pmid:23518214 |
| Philips RC et al. | Mycobacterium fortuitum infection arising in a new tattoo. | 2014 | Dermatol. Online J. | pmid:24945647 |
| Togami K et al. | Involvement of intestinal permeability in the oral absorption of clarithromycin and telithromycin. | 2014 | Biopharm Drug Dispos | pmid:24801141 |
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| Bolhuis MS et al. | In vitro synergy between linezolid and clarithromycin against Mycobacterium tuberculosis. | 2014 | Eur. Respir. J. | pmid:24791826 |
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| Trotti LM et al. | Further experience using clarithromycin in patients with Kleine-Levin syndrome. | 2014 | J Clin Sleep Med | pmid:24733995 |
| Khalili N | Sunny hypomania associated with clarithromycin: a case report. | 2014 | J Clin Psychopharmacol | pmid:24717249 |
| Karaolia P et al. | Reduction of clarithromycin and sulfamethoxazole-resistant Enterococcus by pilot-scale solar-driven Fenton oxidation. | 2014 | Sci. Total Environ. | pmid:24012892 |
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| Suzaki I et al. | Enhancement of thioredoxin production from nasal epithelial cells by the macrolide antibiotic, clarithromycin in vitro. | 2013 May-Jun | In Vivo | pmid:23606690 |
| Dajani AI et al. | Do probiotics improve eradication response to Helicobacter pylori on standard triple or sequential therapy? | 2013 May-Jun | Saudi J Gastroenterol | pmid:23680708 |
| Petitto J et al. | Successful clarithromycin desensitization in a macrolide-sensitive pediatric patient. | 2013 May-Jun | J Allergy Clin Immunol Pract | pmid:24565493 |
| Cottle LE et al. | A multinational outbreak of histoplasmosis following a biology field trip in the Ugandan rainforest. | 2013 Mar-Apr | J Travel Med | pmid:23464714 |
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| Bolhuis MS et al. | Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients. | 2013 | Eur. Respir. J. | pmid:23520311 |
| Schembri S et al. | Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies. | 2013 | BMJ | pmid:23525864 |