clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
pmid:
Dubé MP et al. Successful short-term suppression of clarithromycin-resistant Mycobacterium avium complex bacteremia in AIDS. California Collaborative Treatment Group. 1999 Clin. Infect. Dis. pmid:10028084
Goh KL et al. Optimal treatment for duodenal ulcer disease: a cost-decision analysis in Malaysian patients. 1999 J. Gastroenterol. Hepatol. pmid:10029275
Horgen L et al. Postantibiotic effects of rifampin, amikacin, clarithromycin and ethambutol used alone or in various two-, three- and four-drug combinations against Mycobacterium avium. 1999 FEMS Immunol. Med. Microbiol. pmid:10030545
Sakurai K et al. [Importance of drug selection and the use of sensitivity tests for the eradication therapy for Helicobacter pylori]. 1999 Nippon Rinsho pmid:10036938
Fukazawa K et al. [Antimicrobial resistance testing of H. pylori epsilometer test and disk diffusion test]. 1999 Nippon Rinsho pmid:10036939
Murakami K and Kimoto M [Antibiotic-resistant H. pylori strains in the last ten years in Japan]. 1999 Nippon Rinsho pmid:10036940
Maeda S and Yoshida H [Detection of Helicobacter pylori 23S rRNA gene mutation associated with clarithromycin resistance and its clinical applicability]. 1999 Nippon Rinsho pmid:10036941
Sekine H et al. [Recurrence rate of H. pylori after successful eradication and second eradication therapy after initial failure of treatment]. 1999 Nippon Rinsho pmid:10036947
Iwasaki A [Eradication rate and side effect from a point of view of Helicobacter pylori eradication of peptic ulcer disease in dual therapy or new triple therapy]. 1999 Nippon Rinsho pmid:10036949
Habu Y et al. [Evaluation of the efficacy and the cost-effectiveness of proton pump inhibitor-based dual and triple therapy regimens for H. pylori eradication in peptic ulcer disease]. 1999 Nippon Rinsho pmid:10036950
Shirai T et al. [Four kinds of new triple therapy regiments for Helicobacter pylori eradication in patients with peptic ulcer]. 1999 Nippon Rinsho pmid:10036951
Nakagawa M et al. [A comparative study; one week treatment versus two weeks treatment with lansoprazol, amoxycillin and clarythromycin for the eradication of Helicobacter pylori in patient with gastric and duodenal ulcer]. 1999 Nippon Rinsho pmid:10036952
Kihira K et al. [Triple therapy regimens involving H2 blockaders for therapy of Helicobacter pylori infections]. 1999 Nippon Rinsho pmid:10036953
Goto T et al. [Erosive duodenitis after eradication therapy for Helicobacter pylori]. 1999 Nihon Shokakibyo Gakkai Zasshi pmid:10047687
Wang G et al. Multiplex sequence analysis demonstrates the competitive growth advantage of the A-to-G mutants of clarithromycin-resistant Helicobacter pylori. 1999 Antimicrob. Agents Chemother. pmid:10049289
Woo PC et al. Clarithromycin attenuates the inflammatory response induced by surgical trauma in a guinea pig model. 1999 Pharmacol. Res. pmid:10051377
Kistler A et al. Therapeutic dilemma: crescentic mesangiocapillary glomerulonephritis type 1 in a patient on antituberculous therapy with rifampicin. 1999 Nephrol. Dial. Transplant. pmid:10052525
Yan JJ et al. Disseminated Mycobacterium genavense infection in a patient with acquired immunodeficiency syndrome: first case report in Taiwan. 1999 J. Formos. Med. Assoc. pmid:10063276
Keto Y et al. Healing of Helicobacter pylori-induced gastric ulcers in Mongolian gerbils: combined treatment with omeprazole and clarithromycin. 1999 Dig. Dis. Sci. pmid:10063909
Nilsson F and Walder M [Antibiotic resistance of Helicobacter pylori in Malmö. Therapeutic success in spite of antibiotic resistance]. 1999 Lakartidningen pmid:10064930
Sato K and Tomioka H [In vitro antimicrobial activities of quinolones, rifamycins and macrolides against Mycobacterium tuberculosis and M.avium complex: attempt to establish new assay methods which accurately reflect therapeutic effects of test agents in vivo]. 1999 Kekkaku pmid:10067057
Schultz-Süchting F et al. Treatment of Helicobacter heilmannii-associated gastritis in a 14-year-old boy. 1999 J. Pediatr. Gastroenterol. Nutr. pmid:10067743
Vásconez C et al. Helicobacter pylori, hyperammonemia and subclinical portosystemic encephalopathy: effects of eradication. 1999 J. Hepatol. pmid:10068106
Dehesa M et al. [Comparison of 2 schedules based on pantoprazole for eradication of Helicobacter pylori in patients with active duodenal ulcer]. 1998 Apr-Jun Rev Gastroenterol Mex pmid:10068730
Yajima T et al. Optimum spray congealing conditions for masking the bitter taste of clarithromycin in wax matrix. 1999 Chem. Pharm. Bull. pmid:10071855
Owen RJ Helicobacter pylori resists arrest. 1999 Gut pmid:10075942
Marais A et al. Direct detection of Helicobacter pylori resistance to macrolides by a polymerase chain reaction/DNA enzyme immunoassay in gastric biopsy specimens. 1999 Gut pmid:10075951
Shirtliff ME et al. Oral rifampin plus azithromycin or clarithromycin to treat osteomyelitis in rabbits. 1999 Clin. Orthop. Relat. Res. pmid:10078148
Periti P and Mazzei T Clarithromycin: pharmacokinetic and pharmacodynamic interrelationships and dosage regimen. 1999 J Chemother pmid:10078776
de Jong JJ et al. Atypical mycobacterium infection with dermatological manifestation in a renal transplant recipient. 1999 Transpl. Int. pmid:10080410
Woo MS et al. Pediatric transplant grand rounds. A case presentation: skin lesions in a post-lung transplant patient. 1997 Pediatr Transplant pmid:10084776
Moreau P et al. Lack of efficacy of clarithromycin in advanced multiple myeloma. Intergroupe Français du Myélome (IFM) 1999 Leukemia pmid:10086745
Unge P Antibiotic treatment of Helicobacter pylori infection. 1999 Curr. Top. Microbiol. Immunol. pmid:10087665
Wreiber K et al. [Development of resistant Helicobacter pylori in Sweden. Tendency toward increasing resistance to clarithromycin]. 1999 Lakartidningen pmid:10087796
Sakatani M [Multi-drug resistant mycobacterial infection]. 1999 Ryoikibetsu Shokogun Shirizu pmid:10088372
García-Romero E et al. [Treatment with omeprazole, clarithromycin and amoxicillin over 6 days in patients with Helicobacter pylori-infected duodenal ulcer]. 1999 Gastroenterol Hepatol pmid:10089703
Ramirez J et al. Sparfloxacin versus clarithromycin in the treatment of community-acquired pneumonia. 1999 Clin Ther pmid:10090428
Ong EL Prophylaxis against disseminated Mycobacterium avium complex in AIDS. 1999 J. Infect. pmid:10090497
Sunazuka T et al. Effects of erythromycin and its derivatives on interleukin-8 release by human bronchial epithelial cell line BEAS-2B cells. 1999 J. Antibiot. pmid:10092202
Talley NJ et al. Eradication of Helicobacter pylori in functional dyspepsia: randomised double blind placebo controlled trial with 12 months' follow up. The Optimal Regimen Cures Helicobacter Induced Dyspepsia (ORCHID) Study Group. 1999 BMJ pmid:10092259
Khoo KH et al. Altered expression profile of the surface glycopeptidolipids in drug-resistant clinical isolates of Mycobacterium avium complex. 1999 J. Biol. Chem. pmid:10092667
Torgano G et al. Treatment of Helicobacter pylori and Chlamydia pneumoniae infections decreases fibrinogen plasma level in patients with ischemic heart disease. 1999 Circulation pmid:10096930
Navuluri R and Yue S Understanding peptic ulcer disease pharmacotherapeutics. 1999 Nurse Pract pmid:10100245
Tirén U et al. Helicobacter pylori gastritis in children: efficacy of 2 weeks of treatment with clarithromycin, amoxicillin and omeprazole. 1999 Acta Paediatr. pmid:10102149
Graham DY et al. Ranitidine bismuth citrate, tetracycline, clarithromycin twice-a-day triple therapy for clarithromycin susceptible Helicobacter pylori infection. 1999 Aliment. Pharmacol. Ther. pmid:10102946
Zanten SJ et al. The DU-MACH study: eradication of Helicobacter pylori and ulcer healing in patients with acute duodenal ulcer using omeprazole based triple therapy. 1999 Aliment. Pharmacol. Ther. pmid:10102960
Van der Wouden EJ et al. The influence of metronidazole resistance on the efficacy of ranitidine bismuth citrate triple therapy regimens for Helicobacter pylori infection. 1999 Aliment. Pharmacol. Ther. pmid:10102961
Wong BC et al. Triple therapy for Helicobacter pylori eradication is more effective than long-term maintenance antisecretory treatment in the prevention of recurrence of duodenal ulcer: a prospective long-term follow-up study. 1999 Aliment. Pharmacol. Ther. pmid:10102962
Xiao SD et al. High cure rate of Helicobacter pylori infection using tripotassium dicitrato bismuthate, furazolidone and clarithromycin triple therapy for 1 week. 1999 Aliment. Pharmacol. Ther. pmid:10102963
Liu WZ et al. Furazolidone-containing short-term triple therapies are effective in the treatment of Helicobacter pylori infection. 1999 Aliment. Pharmacol. Ther. pmid:10102964
Huang J and Hunt RH Clarithromycin-based triple therapies. 1999 Aliment. Pharmacol. Ther. pmid:10102978
Kohyama T et al. Fourteen-member macrolides inhibit interleukin-8 release by human eosinophils from atopic donors. 1999 Antimicrob. Agents Chemother. pmid:10103198
Dempsey CL et al. Drug usage evaluation: clarithromycin as sequential therapy. 1993 Hosp Formul pmid:10130382
Craig AM et al. Decision analysis of Helicobacter pylori eradication therapy using omeprazole with either clarithromycin or amoxicillin. 1996 Pharmacoeconomics pmid:10160472
Gimenez Garcia R et al. Fish tank granuloma: response to treatment with clarithromycin. 1999 J Eur Acad Dermatol Venereol pmid:10188167
Fournier S et al. Effect of adding clofazimine to combined clarithromycin-ethambutol therapy for Mycobacterium avium complex septicemia in AIDS patients. 1999 Eur. J. Clin. Microbiol. Infect. Dis. pmid:10192709
Gómez-Gil E et al. Clarithromycin-induced acute psychoses in peptic ulcer disease. 1999 Eur. J. Clin. Microbiol. Infect. Dis. pmid:10192720
Rosário M et al. [Profile of the resistance to macrolides and imidazoles of Helicobacter pylori in a sample of the Portuguese population]. 1998 Acta Med Port pmid:10192979
Lee CK et al. Immunization with recombinant Helicobacter pylori urease decreases colonization levels following experimental infection of rhesus monkeys. 1999 Vaccine pmid:10195786
Verbanck JJ et al. Campylobacter jejuni II peritonitis in a CCPD patient: cure by oral clarithromycin. 1999 Jan-Feb Perit Dial Int pmid:10201350
Sonnenberg A et al. The effect of antibiotic therapy on bleeding from duodenal ulcer. 1999 Am. J. Gastroenterol. pmid:10201462
Smoot DT et al. Effectiveness of ranitidine bismuth citrate, clarithromycin, and metronidazole therapy for treating Helicobacter pylori. 1999 Am. J. Gastroenterol. pmid:10201463
Laine L et al. Once-daily therapy for H. pylori infection: a randomized comparison of four regimens. 1999 Am. J. Gastroenterol. pmid:10201465
Zhou Q et al. CYP2C19 genotypes and omeprazole metabolism after single and repeated dosing when combined with clarithromycin. 1999 Eur. J. Clin. Pharmacol. pmid:10206083
Miwa H et al. Efficacy of 1 week omeprazole or lansoprazole-amoxycillin-clarithromycin therapy for Helicobacter pylori infection in the Japanese population. 1999 J. Gastroenterol. Hepatol. pmid:10207779
Henry DC et al. Comparison of sparfloxacin and clarithromycin in the treatment of acute bacterial maxillary sinusitis. Sparfloxacin Multicenter AMS Study Group. 1999 Clin Ther pmid:10211537
McConnell SA and Amsden GW Review and comparison of advanced-generation macrolides clarithromycin and dirithromycin. 1999 Pharmacotherapy pmid:10212011
Dubois J and St-Pierre C In vitro activity of gatifloxacin, compared with ciprofloxacin, clarithromycin, erythromycin, and rifampin, against Legionella species. 1999 Diagn. Microbiol. Infect. Dis. pmid:10212753
Clifford K et al. Double-blind comparative trial of ciprofloxacin versus clarithromycin in the treatment of acute bacterial sinusitis. Sinusitis Infection Study Group. 1999 Ann. Otol. Rhinol. Laryngol. pmid:10214783
Kashimura H et al. Polaprezinc, a mucosal protective agent, in combination with lansoprazole, amoxycillin and clarithromycin increases the cure rate of Helicobacter pylori infection. 1999 Aliment. Pharmacol. Ther. pmid:10215732
Lee JM et al. Treatment options for Helicobacter pylori infection when proton pump inhibitor-based triple therapy fails in clinical practice. 1999 Aliment. Pharmacol. Ther. pmid:10215733
Neville PM et al. The optimal antibiotic combination in a 5-day Helicobacter pylori eradication regimen. 1999 Aliment. Pharmacol. Ther. pmid:10215734
Hoffman JS et al. Efficacy of a 1-week regimen of ranitidine bismuth citrate in combination with metronidazole and clarithromycin for Helicobacter pylori eradication. 1999 Aliment. Pharmacol. Ther. pmid:10215735
Abbott GW et al. MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia. 1999 Cell pmid:10219239
van der Hulst RW et al. [Treatment of Helicobacter pylori infections]. 1999 Ned Tijdschr Geneeskd pmid:10221109
Khan AA et al. Effect of clarithromycin and azithromycin on production of cytokines by human monocytes. 1999 Int. J. Antimicrob. Agents pmid:10221415
Sato K and Tomioka H Antimicrobial activities of benzoxazinorifamycin (KRM-1648) and clarithromycin against Mycobacterium avium-intracellulare complex within murine peritoneal macrophages, human macrophage-like cells and human alveolar epithelial cells. 1999 J. Antimicrob. Chemother. pmid:10223590
Garey KW et al. Lack of effect of zafirlukast on the pharmacokinetics of azithromycin, clarithromycin, and 14-hydroxyclarithromycin in healthy volunteers. 1999 Antimicrob. Agents Chemother. pmid:10223928
Fish DN and Abraham E Pharmacokinetics of a clarithromycin suspension administered via nasogastric tube to seriously ill patients. 1999 Antimicrob. Agents Chemother. pmid:10223952
Bergman KL et al. Antimicrobial activities and postantibiotic effects of clarithromycin, 14-hydroxy-clarithromycin, and azithromycin in epithelial cell lining fluid against clinical isolates of haemophilus influenzae and Streptococcus pneumoniae. 1999 Antimicrob. Agents Chemother. pmid:10223956
Gisbert JP et al. [Antral biopsy is sufficient to confirm Helicobacter pylori eradication with the "new" one-week long triple treatments]. 1999 Med Clin (Barc) pmid:10227015
Gisbert JP [Lansoprazole: a review of its role in Helicobacter pylori eradication therapy]. 1999 Rev Esp Enferm Dig pmid:10231305
Goddard AF et al. Randomized controlled comparison of nitroimidazoles for the eradication of Helicobacter pylori and relief of ulcer-associated and non-ulcer dyspepsia. 1999 Aliment. Pharmacol. Ther. pmid:10233187
Pilotto A et al. The effect of antibiotic resistance on the outcome of three 1-week triple therapies against Helicobacter pylori. 1999 Aliment. Pharmacol. Ther. pmid:10233191
Hayashi Y et al. Torsades de pointes ventricular tachycardia induced by clarithromycin and disopyramide in the presence of hypokalemia. 1999 Pacing Clin Electrophysiol pmid:10234723
Vakil N and Cutler A Ten-day triple therapy with ranitidine bismuth citrate, amoxicillin, and clarithromycin in eradicating Helicobacter pylori. 1999 Am. J. Gastroenterol. pmid:10235192
Woods GL et al. Multisite reproducibility of results obtained by the broth microdilution method for susceptibility testing of Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum. 1999 J. Clin. Microbiol. pmid:10325306
Warheker PT et al. Successful treatment of saccular endophthalmitis with clarithromycin. 1998 Eye (Lond) pmid:10326009
Carbon C and Poole MD The role of newer macrolides in the treatment of community-acquired respiratory tract infection. A review of experimental and clinical data. 1999 J Chemother pmid:10326741
Le Gars L et al. Polyarthralgia-arthritis syndrome induced by low doses of rifabutin. 1999 J. Rheumatol. pmid:10332992
Bocheńska-Marciniak M et al. [Clinical efficacy and safety of spiramycin and clarithromycin in the treatment of outpatients with lower respiratory tract infections]. 1998 Pol. Arch. Med. Wewn. pmid:10335027
Champney WS and Tober CL Superiority of 11,12 carbonate macrolide antibiotics as inhibitors of translation and 50S ribosomal subunit formation in Staphylococcus aureus cells. 1999 Curr. Microbiol. pmid:10341075
Nitu IC et al. Management of liver failure in a haemophilic patient co-infected with human immunodeficiency and hepatitis C viruses. 1999 Clin Lab Haematol pmid:10342075
Abdul Aal GM et al. Resolution of gastritis induced by Helicobacter pylori 4-5 weeks after successful eradication of infection using a triple therapy regimen of pantoprazole, amoxycillin and clarithromycin for one week. 1999 Digestion pmid:10343145
Dajani AI et al. One-week triple regime therapy consisting of pantoprazole, amoxicillin and clarithromycin for cure of Helicobacter pylori-associated upper gastrointestinal diseases. 1999 Digestion pmid:10343146
Sonnenberg A et al. Antibiotic therapy of Helicobacter pylori infection reduces healthcare expenditures related to duodenal ulcer. 1999 Am J Manag Care pmid:10345967
Champney WS and Tober CL Molecular investigation of the postantibiotic effects of clarithromycin and erythromycin on Staphylococcus aureus cells. 1999 Antimicrob. Agents Chemother. pmid:10348746
Debets-Ossenkopp YJ et al. Prevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxycillin, tetracycline and trovafloxacin in The Netherlands. 1999 J. Antimicrob. Chemother. pmid:10350380
Son SW et al. The response of rosacea to eradication of Helicobacter pylori. 1999 Br. J. Dermatol. pmid:10354058