| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Granda MartÃn MJ et al. | [Mycoplasma-associated acute hepatitis in an adult patient without pulmonary involvement]. | Gastroenterol Hepatol | pmid:24569138 | |
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| Monego F et al. | Molecular identification and typing of Mycobacterium massiliense isolated from postsurgical infections in Brazil. | Braz J Infect Dis | pmid:22230849 | |
| Kim MD et al. | Ergotamine-induced upper extremity ischemia: a case report. | Korean J Radiol | pmid:15968153 | |
| Dharmalingam S et al. | Relationship of plasmid profile with the antibiotic sensitivity pattern of Helicobacter pylori isolates from peptic ulcer disease patients in Chennai. | Indian J Med Microbiol | pmid:17643038 | |
| Kekilli M et al. | Inefficacy of triple therapy and comparison of two different bismuth-containing quadruple regimens as a firstline treatment option for helicobacter pylori. | Saudi J Gastroenterol | pmid:27748322 | |
| Ikeda H et al. | Severe Disseminated Mycobacterium avium Infection in a Patient with a Positive Serum Autoantibody to Interferon-γ. | Intern. Med. | pmid:27746449 | |
| Siemens J et al. | Transport of pharmaceuticals in columns of a wastewater-irrigated Mexican clay soil. | J. Environ. Qual. | pmid:20830907 | |
| Walrave TR et al. | [Mania induced by antibiotic therapy]. | Tijdschr Psychiatr | pmid:27527887 | |
| Ubhayawardana NL et al. | Detection of clarithromycin-resistant Helicobacter pylori strains in a dyspeptic patient population in Sri Lanka by polymerase chain reaction-restriction fragment length polymorphism. | Indian J Med Microbiol | pmid:26068338 | |
| Baylor P and Larson R | Mycobacterium avium septicemia with ARDS in a patient with diabetes mellitus and no other known immune-compromising condition. | J Intensive Care Med | pmid:19188269 | |
| Set R and Shastri J | Laboratory aspects of clinically significant rapidly growing mycobacteria. | Indian J Med Microbiol | pmid:22120792 | |
| Kim HY et al. | Allele-specific duplex polymerase chain reaction to differentiate Mycobacterium abscessus subspecies and to detect highly clarithromycin-resistant isolates. | Indian J Med Microbiol | pmid:27514964 | |
| Colomina RodrÃguez J et al. | [Impact of Integrated Model for Rational Use of Antibiotics in a health area (project MIURA)]. | Rev. Esp. Salud Publica | pmid:20661527 | |
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| Vicente R et al. | [Helicobacter pylori eradication in patients with peptic ulcer after two treatment failures: a prospective culture-guided study]. | Gastroenterol Hepatol | pmid:12139836 | |
| Yoon HJ et al. | Nontuberculous mycobacterial tenosynovitis in the hand: two case reports with the MR imaging findings. | Korean J Radiol | pmid:22043158 | |
| Lage R et al. | Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease. | An Bras Dermatol | pmid:25672306 | |
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| Horiguchi T et al. | Antibacterial activity and clinical efficacy of sparfloxacin in Mycobacterium avium-intracellulare complex infection. | J. Int. Med. Res. | pmid:15458286 | |
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| Mishra A et al. | A rare debilitating neurological adverse effect of ranolazine due to drug interaction with clarithromycin. | Indian J Pharmacol | pmid:25298587 | |
| Lew EA | Clarithromycin, lansoprazole, and metronidazole eradicated Helicobacter pylori infection in chronic renal insufficiency. | ACP J. Club | pmid:15122860 | |
| Lindeboom JA | Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria. | Pediatr Dermatol | pmid:26823205 | |
| pmid:11817788 | ||||
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| Liang CM et al. | Levofloxacin-containing second-line anti-Helicobacter pylori eradication in Taiwanese real-world practice. | Biomed J | pmid:25163495 | |
| Wang J et al. | Two-week triple therapy has a higher Helicobacter pylori eradication rate than 1-week therapy: A single-center randomized study. | Saudi J Gastroenterol | pmid:26655129 | |
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| Moreira C et al. | Symmetrical drug-related intertriginous and flexural exanthema induced by clarithromycin. | An Bras Dermatol | pmid:28954125 | |
| Gościniak G et al. | Frequency of infection with Helicobacter pylori isolates of different antimicrobial profiles in children and adolescents: A preliminary study. | Adv Clin Exp Med | pmid:28791844 | |
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| Cavkaytar O et al. | Testing for clarithromycin hypersensitivity: A diagnostic challenge in childhood. | J Allergy Clin Immunol Pract | pmid:26489714 | |
| Seitz CS et al. | Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. | Allergol Immunopathol (Madr) | pmid:21269750 | |
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| Moreira A et al. | Is Helicobacter pylori infection associated with chronic idiopathic urticaria? | Allergol Immunopathol (Madr) | pmid:12890412 | |
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| Pachot JI et al. | Experimental estimation of the role of P-Glycoprotein in the pharmacokinetic behaviour of telithromycin, a novel ketolide, in comparison with roxithromycin and other macrolides using the Caco-2 cell model. | J Pharm Pharm Sci | pmid:12753725 | |
| Lin TY et al. | An open-label, randomized comparison of levofloxacin and amoxicillin/clavulanate plus clarithromycin for the treatment of hospitalized patients with community-acquired pneumonia. | Chang Gung Med J | pmid:17939262 | |
| Radzikowska E et al. | Clarithromycin Decreases IL-6 Concentration in Serum and BAL Fluid in Patients with Cryptogenic Organizing Pneumonia. | Adv Clin Exp Med | pmid:28028949 |