clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Adamek RJ et al. Modified short-term triple therapy--ranitidine, clarithromycin, and metronidazole--for cure of Helicobacter pylori infection. 1995 Am. J. Gastroenterol. pmid:7801936
Savarino V et al. Helicobacter pylori eradication and reinfection. 1995 Lancet pmid:7783564
Comley JC and Sterling AM Effect of atovaquone and atovaquone drug combinations on prophylaxis of Pneumocystis carinii pneumonia in SCID mice. 1995 Antimicrob. Agents Chemother. pmid:7785975
Struillou L et al. Activities of roxithromycin against Mycobacterium avium infections in human macrophages and C57BL/6 mice. 1995 Antimicrob. Agents Chemother. pmid:7785988
Fong IW et al. Clarithromycin versus cefaclor in lower respiratory tract infections. The Canadian Bronchitis Study Group. 1995 Clin Invest Med pmid:7788958
Goddard A and Logan R One-week low-dose triple therapy: new standards for Helicobacter pylori treatment. 1995 Eur J Gastroenterol Hepatol pmid:7866804
Labenz J et al. One-week low-dose triple therapy for the eradication of Helicobacter pylori infection. 1995 Eur J Gastroenterol Hepatol pmid:7866820
Weits J and Sprenger HG [Surgical treatment of lymphadenitis caused by non-tuberculous mycobacteria in children]. 1995 Ned Tijdschr Geneeskd pmid:8524431
Nash KA and Inderlied CB Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease. 1995 Antimicrob. Agents Chemother. pmid:8592991
Gill CJ et al. In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin. 1995 J. Antibiot. pmid:7490222
Gelber RH Successful treatment of a lepromatous patient with clarithromycin. 1995 Int. J. Lepr. Other Mycobact. Dis. pmid:7730711
Adamek RJ et al. [Short-term triple therapy with pantoprazole, clarithromycin and metronidazole for the healing of Helicobacter pylori infection]. 1995 Dtsch. Med. Wochenschr. pmid:7889816
Midoneck SR and Etingin OR Clarithromycin-related toxic effects of digoxin. 1995 N. Engl. J. Med. pmid:7477159
Forslund T et al. Disseminated cutaneous infection due to Mycobacterium chelonae in a patient with rheumatoid arthritis, amyloidosis, and renal failure. 1995 Nephrol. Dial. Transplant. pmid:7478131
Fabry W et al. Comparison of the E test and a proportion dilution method for susceptibility testing of Mycobacterium tuberculosis. 1995 Zentralbl. Bakteriol. pmid:9810662
Katelaris PH et al. A randomized prospective comparison of clarithromycin versus amoxycillin in combination with omeprazole for eradication of Helicobacter pylori. 1995 Aliment. Pharmacol. Ther. pmid:7605864
Yousfi MM et al. Metronidazole, omeprazole and clarithromycin: an effective combination therapy for Helicobacter pylori infection. 1995 Aliment. Pharmacol. Ther. pmid:7605865
Chevalley GF et al. [Uveitis associated with rifabutin treatment. Apropos of 3 patients]. 1995 Klin Monbl Augenheilkd pmid:7609395
Blum AL et al. [Functional dyspepsia: approaches to Helicobacter pylori eradication therapy]. 1995 Leber Magen Darm pmid:7609589
Labenz J et al. [Short-term triple therapy with pantoprazole, clarithromycin and metronidazole in eradication of Helicobacter pylori]. 1995 Leber Magen Darm pmid:7609590
Reppun JI From prontolyn to biaxin: the half-century of antibiotics. 1995 Hawaii Med J pmid:7628918
Chin DP and Hopewell PC How to treat bacteraemic Mycobacterium avium complex disease. 1995 Lancet pmid:7564723
Kuhn SM et al. Treatment of Mycobacterium marinum facial abscess using clarithromycin. 1995 Pediatr. Infect. Dis. J. pmid:7567299
Lacassin F et al. Clarithromycin-minocycline combination as salvage therapy for toxoplasmosis in patients infected with human immunodeficiency virus. 1995 Antimicrob. Agents Chemother. pmid:7695324
Labenz J and Börsch G Toward an optimal treatment of Helicobacter pylori-positive peptic ulcers. 1995 Am. J. Gastroenterol. pmid:7733070
Forné M et al. Impact of colloidal bismuth subnitrate in the eradication rates of Helicobacter pylori infection-associated duodenal ulcer using a short treatment regimen with omeprazole and clarithromycin: a randomized study. 1995 Am. J. Gastroenterol. pmid:7733075
Schlossberg D Azithromycin and clarithromycin. 1995 Med. Clin. North Am. pmid:7791424
Schütze K and Hentschel E Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. 1995 Z Gastroenterol pmid:8600661
Tseng AL and Walmsley SL Rifabutin-associated uveitis. 1995 Ann Pharmacother pmid:8573961
Moayyedi P et al. Efficacy and optimum dose of omeprazole in a new 1-week triple therapy regimen to eradicate Helicobacter pylori. 1995 Eur J Gastroenterol Hepatol pmid:8574714
Fujioka T et al. Peptic ulcer recurrence after Helicobacter pylori eradication: a 5-year follow-up study. 1995 Eur J Gastroenterol Hepatol pmid:8574733
Deltenre M et al. Omeprazole-based antimicrobial therapies: results in 198 Helicobacter pylori-positive patients. 1995 Eur J Gastroenterol Hepatol pmid:8574734
Fukuda Y et al. Combination therapy with mucosal protective agent for the eradication of Helicobacter pylori. 1995 Eur J Gastroenterol Hepatol pmid:8574735
Graham DY Clarithromycin for treatment of Helicobacter pylori infections. 1995 Eur J Gastroenterol Hepatol pmid:8574737
Takimoto T et al. Dual therapy with lansoprazole and clarithromycin for eradication of Helicobacter pylori. 1995 Eur J Gastroenterol Hepatol pmid:8574739
Uemura N et al. Effect of Helicobacter pylori eradication on the healing and recurrence of peptic ulcer: combination therapy with low-dose omeprazole and clarithromycin. 1995 Eur J Gastroenterol Hepatol pmid:8574740
Pavlopoulou J et al. Randomized controlled study of clarithromycin versus cefaclor suspensions in the treatment of acute otitis media in children. 1995 J Chemother pmid:8904139
Gioulekas J and Hall A Uveitis associated with rifabutin therapy. 1995 Aust N Z J Ophthalmol pmid:11980079
Nishi K et al. [Effect of clarithromycin on symptoms and mucociliary transport in patients with sino-bronchial syndrome]. 1995 Nihon Kyobu Shikkan Gakkai Zasshi pmid:8821993
Van Asselt GJ et al. Susceptibility of Streptococcus pyogenes to azithromycin, clarithromycin, erythromycin and roxithromycin in vitro. 1995 J. Med. Microbiol. pmid:7563004
Wallace RJ et al. Reduced serum levels of clarithromycin in patients treated with multidrug regimens including rifampin or rifabutin for Mycobacterium avium-M. intracellulare infection. 1995 J. Infect. Dis. pmid:7876634
Moorthy RS and Rao NA Atypical mycobacterial wound infection after blepharoplasty. 1995 Br J Ophthalmol pmid:7880802
Yoshizawa A et al. [Legionella pneumonia diagnosed by urinary antigen detection]. 1995 Nihon Kyobu Shikkan Gakkai Zasshi pmid:7791279
Lounis N et al. Selection of clarithromycin-resistant Mycobacterium avium complex during combined therapy using the beige mouse model. 1995 Antimicrob. Agents Chemother. pmid:7793860
Fattorini L et al. In vitro and ex vivo activities of antimicrobial agents used in combination with clarithromycin, with or without amikacin, against Mycobacterium avium. 1995 Antimicrob. Agents Chemother. pmid:7793873
Cohen Y et al. Use of normal C57BL/6 mice with established Mycobacterium avium infections as an alternative model for evaluation of antibiotic activity. 1995 Antimicrob. Agents Chemother. pmid:7793882
Furney SK et al. Activities of rifabutin, clarithromycin, and ethambutol against two virulent strains of Mycobacterium avium in a mouse model. 1995 Antimicrob. Agents Chemother. pmid:7793895
Brown BA et al. Clarithromycin-induced hepatotoxicity. 1995 Clin. Infect. Dis. pmid:7795060
Raffi F et al. Breakthrough cerebral toxoplasmosis in patients with AIDS who are being treated with clarithromycin. 1995 Clin. Infect. Dis. pmid:7795062
Sharma PK and Tami TA AIDS: lessons from the last decade and prospects for the future. 1995 Ear Nose Throat J pmid:7796740