| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sawada A | [Gastroduodenal ulcer in childhood]. | 2002 | Nippon Rinsho | pmid:11979854 |
| Watanabe T and Chiba T | [Peptic ulcer in the elderly]. | 2002 | Nippon Rinsho | pmid:11979855 |
| Sugano K | [Role of proton pump inhibitors in the eradication therapy for Helicobacter pylori (overviews)]. | 2002 | Nippon Rinsho | pmid:11979859 |
| Iwasaki A | [Proton pump inhibitors: Omeprazole]. | 2002 | Nippon Rinsho | pmid:11979860 |
| Kawata H and Satoh K | [Proton pump inhibitors: Efficacy of lansoprazole in eradicating Helicobacter pylori]. | 2002 | Nippon Rinsho | pmid:11979862 |
| Yoshino J | [Proton pump inhibitors: Rabeprazole]. | 2002 | Nippon Rinsho | pmid:11979863 |
| Murakami K and Nasu M | [Clarithromycin (CAM)]. | 2002 | Nippon Rinsho | pmid:11979867 |
| Yakabi K and Nakamura T | [The role of H2RA in the eradication therapy of Helicobacter pylori]. | 2002 | Nippon Rinsho | pmid:11979869 |
| Hiraishi H et al. | [Sucralfate]. | 2002 | Nippon Rinsho | pmid:11979871 |
| Ito S et al. | [Plaunotol]. | 2002 | Nippon Rinsho | pmid:11979873 |
| Fukuda Y and Shimoyama T | [Sofalcone]. | 2002 | Nippon Rinsho | pmid:11979875 |
| Kuwayama H et al. | [Polaprezinc]. | 2002 | Nippon Rinsho | pmid:11979877 |
| Kamada T et al. | [Non-ulcer dyspepsia and H. pylori]. | 2002 | Nippon Rinsho | pmid:11979887 |
| Yamamoto T et al. | [CRHP (clarithromycin-resistant H. pylori) infection in children]. | 2002 | Nippon Rinsho | pmid:11979889 |
| Isomoto H and Kohno S | [Helicobacter heilmannii-associated gastritis]. | 2002 | Nippon Rinsho | pmid:11979890 |
| Gioulekas J and Hall A | Uveitis associated with rifabutin therapy. | 1995 | Aust N Z J Ophthalmol | pmid:11980079 |
| Critchley IA et al. | Antimicrobial resistance in respiratory pathogens isolated in Brazil during 1999-2000. | 2001 | Braz J Infect Dis | pmid:11980591 |
| Wermeille J et al. | Failure of Helicobacter pylori eradication: is poor compliance the main cause? | 2002 | Gastroenterol. Clin. Biol. | pmid:11981460 |
| Goh KL | Update on the management of Helicobacter pylori infection, including drug-resistant organisms. | 2002 | J. Gastroenterol. Hepatol. | pmid:11982731 |
| Scott LJ et al. | Esomeprazole: a review of its use in the management of acid-related disorders in the US. | 2002 | Drugs | pmid:11985491 |
| Taylor RH et al. | Possible cat scratch disease causing neuroretinitis and CRVO in a child. | 2002 | Eye (Lond) | pmid:11988821 |
| Sugano K | [Practice guidelines for diagnosis and treatment of Helicobacter pylori infections and their application in clinical practice]. | 2002 | Nippon Naika Gakkai Zasshi | pmid:11989260 |
| Marchisio P et al. | Nasopharyngeal carriage of Streptococcus pneumoniae in healthy children: implications for the use of heptavalent pneumococcal conjugate vaccine. | 2002 | Emerging Infect. Dis. | pmid:11996682 |
| Cuchà Burgos E et al. | [Evolution of the sensitivity of 235 strains of Helicobacter pylori from 1995 to 1998 and impact of antibiotic treatment]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:11996701 |
| Champney WS and Miller M | Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin. | 2002 | Curr. Microbiol. | pmid:12000992 |
| Grignon B et al. | Validation of diffusion methods for macrolide susceptibility testing of Helicobacter pylori. | 2002 | Microb. Drug Resist. | pmid:12002651 |
| Kikuchi T et al. | Clarithromycin suppresses lipopolysaccharide-induced interleukin-8 production by human monocytes through AP-1 and NF-kappa B transcription factors. | 2002 | J. Antimicrob. Chemother. | pmid:12003967 |
| Yanagihara K et al. | Effect of clarithromycin on chronic respiratory infection caused by Pseudomonas aeruginosa with biofilm formation in an experimental murine model. | 2002 | J. Antimicrob. Chemother. | pmid:12003986 |
| Wedi B and Kapp A | Helicobacter pylori infection in skin diseases: a critical appraisal. | 2002 | Am J Clin Dermatol | pmid:12010072 |
| Holdiness MR | Management of cutaneous erythrasma. | 2002 | Drugs | pmid:12010076 |
| Cuffini AM et al. | Clarithromycin mediated the expression of polymorphonuclear granulocyte response against streptococcus pneumoniae strains with different patterns of susceptibility and resistance to penicillin and clarithromycin. | 2002 | Int J Tissue React | pmid:12013153 |
| Stein GE and Schooley S | Serum bactericidal activity of extended-release clarithromycin against macrolide-resistant strains of Streptococcus pneumoniae. | 2002 | Pharmacotherapy | pmid:12013358 |
| Yamane N et al. | [Multicenter evaluation of a newly developed microdilution test, brothMIC NTM to determine minimum inhibitory concentrations of antimicrobial agents for nontuberculous mycobacteria]. | 2002 | Rinsho Byori | pmid:12014018 |
| Konturek PC et al. | Gastric MALT-lymphoma, gastrin and cyclooxygenases. | 2002 Jan-Mar | Acta Gastroenterol. Belg. | pmid:12014312 |
| Braga PC | Rokitamycin: bacterial resistance to a 16-membered ring macrolide differs from that to 14- and 15-membered ring macrolides. | 2002 | J Chemother | pmid:12017366 |
| Critchley IA et al. | Antimicrobial resistance among respiratory pathogens collected in Thailand during 1999-2000. | 2002 | J Chemother | pmid:12017369 |
| Moore KH et al. | The pharmacokinetics of sumatriptan when administered with clarithromycin in healthy volunteers. | 2002 | Clin Ther | pmid:12017403 |
| Sokol WN et al. | A prospective, double-blind, multicenter study comparing clarithromycin extended-release with trovafloxacin in patients with community-acquired pneumonia. | 2002 | Clin Ther | pmid:12017405 |
| Wilson R et al. | A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes. | 2002 | Clin Ther | pmid:12017408 |
| Karczewska E et al. | Oral cavity as a potential source of gastric reinfection by Helicobacter pylori. | 2002 | Dig. Dis. Sci. | pmid:12018924 |
| Finch R et al. | Randomized controlled trial of sequential intravenous (i.v.) and oral moxifloxacin compared with sequential i.v. and oral co-amoxiclav with or without clarithromycin in patients with community-acquired pneumonia requiring initial parenteral treatment. | 2002 | Antimicrob. Agents Chemother. | pmid:12019085 |
| Prazeres Magalhães P et al. | Helicobacter pylori primary resistance to metronidazole and clarithromycin in Brazil. | 2002 | Antimicrob. Agents Chemother. | pmid:12019131 |
| Piana A et al. | Genotypic characterization of clarithromycin-resistant Helicobacter pylori strains. | 2002 | New Microbiol. | pmid:12019717 |
| Jang SS and Hirsh DC | Rapidly growing members of the genus Mycobacterium affecting dogs and cats. | 2002 May-Jun | J Am Anim Hosp Assoc | pmid:12022405 |
| Uriarte SM et al. | Effect of macrolide antibiotics on human endothelial cells activated by Chlamydia pneumoniae infection and tumor necrosis factor-alpha. | 2002 | J. Infect. Dis. | pmid:12023769 |
| Greub G and Raoult D | Parachlamydiaceae: potential emerging pathogens. | 2002 | Emerging Infect. Dis. | pmid:12023921 |
| KorotkyÄ VM and Kolosovych IV | [Pharmacotherapeutic aspects of early postoperative period in patients with complicated gastroduodenal ulcer]. | 2002 | Klin Khir | pmid:12024723 |
| Trübel HK et al. | Complicated nosocomial pneumonia due to Legionella pneumophila in an immunocompromised child. | 2002 | Scand. J. Infect. Dis. | pmid:12030402 |
| Pauwels O | Factors contributing to carbamazepine-macrolide interactions. | 2002 | Pharmacol. Res. | pmid:12030792 |
| Gisbert JP and Pajares JM | Review article: Helicobacter pylori "rescue" regimen when proton pump inhibitor-based triple therapies fail. | 2002 | Aliment. Pharmacol. Ther. | pmid:12030945 |
| Laine L and Dhir V | Helicobacter pylori eradication does not worsen quality of life related to reflux symptoms: a prospective trial. | 2002 | Aliment. Pharmacol. Ther. | pmid:12030957 |
| Vallve M et al. | Single vs. double dose of a proton pump inhibitor in triple therapy for Helicobacter pylori eradication: a meta-analysis. | 2002 | Aliment. Pharmacol. Ther. | pmid:12030958 |
| Colin R | Duodenal ulcer healing with 1-week eradication triple therapy followed, or not, by anti-secretory treatment: a multicentre double-blind placebo-controlled trial. | 2002 | Aliment. Pharmacol. Ther. | pmid:12030959 |
| Suzuki T et al. | Localization of antigen-presenting cells in Helicobacter pylori-infected gastric mucosa. | 2002 | Pathol. Int. | pmid:12031081 |
| Gené E et al. | [Management of dyspepsia, gastroduodenal ulcer and Helicobacter pylori infection in primary care]. | 2002 | Aten Primaria | pmid:12031222 |
| Musto P et al. | Inefficacy of clarithromycin in advanced multiple myeloma: a definitive report. | 2002 | Haematologica | pmid:12031924 |
| Fahey JW et al. | Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12032331 |
| Palmas F et al. | Eradication of Helicobacter pylori infection with proton pump inhibitor-based triple therapy. A randomised study. | 2002 | Panminerva Med | pmid:12032434 |
| Scarpellini P et al. | Direct detection of Helicobacter pylori mutations associated with macrolide resistance in gastric biopsy material taken from human immunodeficiency virus-infected subjects. | 2002 | J. Clin. Microbiol. | pmid:12037095 |
| Kountouras J et al. | Eradication of Helicobacter pylori may be beneficial in the management of chronic open-angle glaucoma. | 2002 | Arch. Intern. Med. | pmid:12038941 |
| Samra Z et al. | Resistance of Helicobacter pylori isolated in Israel to metronidazole, clarithromycin, tetracycline, amoxicillin and cefixime. | 2002 | J. Antimicrob. Chemother. | pmid:12039897 |
| Gościmski A et al. | [Microflora of gastric juice in patients after eradication of Helicobacter pylori and treatment with a proton pump inhibitor]. | 2002 | Wiad. Lek. | pmid:12043311 |
| Teh CL et al. | Mycobacterium haemophilum infection in an SLE patient on mycophenolate mofetil. | 2002 | Lupus | pmid:12043889 |
| Fox JC et al. | Progressive cholestatic liver disease associated with clarithromycin treatment. | 2002 | J Clin Pharmacol | pmid:12043957 |
| Vasil'ev IuV and Kolomiets EV | [Treatment of patients with ulcer associated with Helicobacter pylori (experience with a triple therapy regimen]. | 2002 | Eksp Klin Gastroenterol | pmid:12046383 |
| Vasil'ev IuV and Kas'ianenko VI | [Efficacy of the one week treatment with esomeprazole (nexium), clarythromycin, and amoxycillin of duodenal ulcer associated with Helicobacter pylori]. | 2002 | Eksp Klin Gastroenterol | pmid:12046387 |
| Laine L | Review article: esomeprazole in the treatment of Helicobacter pylori. | 2002 | Aliment. Pharmacol. Ther. | pmid:12047270 |
| Critchley IA et al. | In vitro activity of levofloxacin against contemporary clinical isolates of Legionella pneumophila, Mycoplasma pneumoniae and Chlamydia pneumoniae from North America and Europe. | 2002 | Clin. Microbiol. Infect. | pmid:12047413 |
| Sridhar MS et al. | Nocardia asteroides sclerokeratitis in a contact lens wearer. | 2002 | CLAO J | pmid:12054371 |
| Knippig C et al. | Prevalence of H. pylori-infection in family members of H. pylori positive and its influence on the reinfection rate after successful eradication therapy: a two-year follow-up. | 2002 | Z Gastroenterol | pmid:12055660 |
| Lane JA et al. | A placebo-controlled randomized trial of eradication of Helicobacter pylori in the general population: study design and response rates of the Bristol Helicobacter Project. | 2002 | Control Clin Trials | pmid:12057883 |
| Archer JS and Archer DF | Oral contraceptive efficacy and antibiotic interaction: a myth debunked. | 2002 | J. Am. Acad. Dermatol. | pmid:12063491 |
| Kraft M et al. | Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin. | 2002 | Chest | pmid:12065339 |
| Volberg WA et al. | Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12065733 |
| Ozdemir A et al. | Detection of Helicobacter pylori colonization in dental plaques and tongue scrapings of patients with chronic gastritis. | 2001 | Quintessence Int | pmid:12066673 |
| Nicholson SC et al. | Antimicrobial-associated acute hepatitis. | 2002 | Pharmacotherapy | pmid:12066973 |
| Li Y et al. | [Attenuated mRNA induction of molecules associated with neutrophil migration by 14-membered ring macrolides inhibits bleomycin induced acute lung injury in mice]. | 2002 | J Nippon Med Sch | pmid:12068316 |
| Svensson M et al. | Pharmacodynamic effects of nitroimidazoles alone and in combination with clarithromycin on Helicobacter pylori. | 2002 | Antimicrob. Agents Chemother. | pmid:12069981 |
| Treiber G and Malfertheiner P | [Helicobacter pylori--2002]. | 2002 | Praxis (Bern 1994) | pmid:12071078 |
| Daxböck F et al. | A case of lung transplantation following Mycoplasma pneumoniae infection. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:12072947 |
| Bózsik BP | [Comment on Borrelia burgdorferi Group infections]. | 2002 | Orv Hetil | pmid:12073543 |
| Cervin A et al. | One-year low-dose erythromycin treatment of persistent chronic sinusitis after sinus surgery: clinical outcome and effects on mucociliary parameters and nasal nitric oxide. | 2002 | Otolaryngol Head Neck Surg | pmid:12075221 |
| Gotfried MH et al. | A controlled, double-blind, multicenter study comparing clarithromycin extended-release tablets and levofloxacin tablets in the treatment of community-acquired pneumonia. | 2002 | Clin Ther | pmid:12075942 |
| Schito GC et al. | Antibacterial activity of oral antibiotics against community-acquired respiratory pathogens from three European countries. | 2002 | J. Antimicrob. Chemother. | pmid:12077154 |
| Giacometti A et al. | In vitro effect of short-term exposure to two synthetic peptides, alone or in combination with clarithromycin or rifabutin, on Cryptosporidium parvum infectivity. | 2002 | Peptides | pmid:12084535 |
| An infection-fighting drug appears to protect heart patients. | 2002 | Heart Advis | pmid:12085834 | |
| Blaser MJ | The genetic gymnastics of our indigenous microbes. | 2002 | N. Engl. J. Med. | pmid:12087147 |
| Beghi G et al. | [Clarithromycin switch therapy in adult patients suffering from community-acquired lower respiratory tract infections (LRTIs) requiring hospitalisation]. | 2001 | Infez Med | pmid:12087209 |
| Shaffer D et al. | Concomitant risk factors in reports of torsades de pointes associated with macrolide use: review of the United States Food and Drug Administration Adverse Event Reporting System. | 2002 | Clin. Infect. Dis. | pmid:12087527 |
| Bayes M et al. | Gateways to Clinical Trials. | 2002 | Methods Find Exp Clin Pharmacol | pmid:12087878 |
| Stricker RB et al. | Longterm decrease in the CD57 lymphocyte subset in a patient with chronic Lyme disease. | 2002 | Ann Agric Environ Med | pmid:12088407 |
| Bayes M et al. | Gateways to clinical trials. | 2002 | Methods Find Exp Clin Pharmacol | pmid:12092009 |
| Scott LJ et al. | Esomeprazole: a review of its use in the management of acid-related disorders. | 2002 | Drugs | pmid:12093317 |
| Richter E et al. | Mycobacterium avium subsp. paratuberculosis infection in a patient with HIV, Germany. | 2002 | Emerging Infect. Dis. | pmid:12095444 |
| Kobayashi T et al. | Macrolide-treated Pseudomonas aeruginosa induces paradoxical host responses in the lungs of mice and a high mortality rate. | 2002 | J. Antimicrob. Chemother. | pmid:12096007 |
| Kobayashi I et al. | In vitro anti-Helicobacter pylori activity of BAS-118, a new benzamide derivative. | 2002 | J. Antimicrob. Chemother. | pmid:12096019 |
| Koga T et al. | Effect of plaunotol in combination with clarithromycin or amoxicillin on Helicobacter pylori in vitro and in vivo. | 2002 | J. Antimicrob. Chemother. | pmid:12096020 |
| Velasco BenÃtez CA and Amorocho Pérez RD | [Treatment of gastritis-associated Helicobacter pylori infection in children]. | 2002 Apr-Jun | Rev Gastroenterol Peru | pmid:12098744 |
| Nannini EC et al. | Successful treatment of refractory disseminated Mycobacterium avium complex infection with the addition of linezolid and mefloquine. | 2002 | J. Infect. | pmid:12099753 |
| Lin YC et al. | Cutaneous Mycobacterium fortuitum infection mimicking lupus vulgaris. | 2002 | Br. J. Dermatol. | pmid:12100204 |