| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Saviola G et al. | Clarithromycin in rheumatoid arthritis patients not responsive to disease-modifying antirheumatic drugs: an open, uncontrolled pilot study. | 2002 May-Jun | Clin. Exp. Rheumatol. | pmid:12102474 |
| Gómez Gil E et al. | [Three new cases of severe affective disorders induced by clarithromycin]. | 2002 | Med Clin (Barc) | pmid:12106545 |
| Satoh K | Indications for Helicobacter pylori eradication therapy and first-line therapy regimen in Japan: recommendation by the Japanese Society for Helicobacter Research. | 2002 | J. Gastroenterol. | pmid:12109663 |
| Kumazawa J and Yagisawa M | The history of antibiotics: the Japanese story. | 2002 | J. Infect. Chemother. | pmid:12111564 |
| Matute AJ et al. | Double-blind, placebo-controlled study comparing the effect of azithromycin with clarithromycin on oropharyngeal and bowel microflora in volunteers. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:12111597 |
| Tagaya E et al. | Effect of a short course of clarithromycin therapy on sputum production in patients with chronic airway hypersecretion. | 2002 | Chest | pmid:12114361 |
| Todisco T et al. | An open, comparative pilot study of thiamphenicol glycinate hydrochloride vs clarithromycin in the treatment of acute lower respiratory tract infections due to Chlamydia pneumoniae. | 2002 | J Chemother | pmid:12120881 |
| Inaba T et al. | Randomized open trial for comparison of proton pump inhibitors in triple therapy for Helicobacter pylori infection in relation to CYP2C19 genotype. | 2002 | J. Gastroenterol. Hepatol. | pmid:12121503 |
| Fong IW et al. | Influence of clarithromycin on early atherosclerotic lesions after Chlamydia pneumoniae infection in a rabbit model. | 2002 | Antimicrob. Agents Chemother. | pmid:12121899 |
| Schilling D et al. | [Eradication of helicobacter pylori: symptomatic treatment of reflux disease?]. | 2002 | Z Gastroenterol | pmid:12122605 |
| Eltahawy AT | Prevalence of primary Helicobacter pylori resistance to several antimicrobials in a Saudi Teaching Hospital. | 2002 Apr-Jun | Med Princ Pract | pmid:12123105 |
| Williams JA et al. | Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7. | 2002 | Drug Metab. Dispos. | pmid:12124305 |
| Fukai T et al. | Anti-Helicobacter pylori flavonoids from licorice extract. | 2002 | Life Sci. | pmid:12127165 |
| Fulcher SF et al. | Delayed-onset mycobacterial keratitis after LASIK. | 2002 | Cornea | pmid:12131028 |
| Antibiotics for heart health? | 2002 | Health News | pmid:12132417 | |
| Ito I et al. | Familial cases of psittacosis: possible person-to-person transmission. | 2002 | Intern. Med. | pmid:12132529 |
| Johnson TJ and Hedge DD | Esomeprazole: a clinical review. | 2002 | Am J Health Syst Pharm | pmid:12132559 |
| Halpern MT et al. | Cost-effectiveness of gemifloxacin: results from the GLOBE study. | 2002 | Am J Health Syst Pharm | pmid:12132563 |
| Wallace Jr RJ et al. | Repeat positive cultures in Mycobacterium intracellulare lung disease after macrolide therapy represent new infections in patients with nodular bronchiectasis. | 2002 | J. Infect. Dis. | pmid:12134265 |
| Scholte GH et al. | Genotyping of Helicobacter pylori in paraffin-embedded gastric biopsy specimens: relation to histological parameters and effects on therapy. | 2002 | Am. J. Gastroenterol. | pmid:12135019 |
| Sugiyama T et al. | Improvement of long-standing iron-deficiency anemia in adults after eradication of Helicobacter pylori infection. | 2002 | Intern. Med. | pmid:12135186 |
| Kobashi Y et al. | [Effect of combined chemotherapy following the guidelines on treatment for Mycobacterium avium complex pulmonary disease]. | 2002 | Kekkaku | pmid:12136597 |
| Decazes JM | [What shall we make of the arrival of "generalized" antibiotics to anti-Hansen's therapy?]. | 2001-2002 | Acta Leprol | pmid:12136737 |
| Kohda K et al. | Effect of Helicobacter pylori eradication on platelet recovery in Japanese patients with chronic idiopathic thrombocytopenic purpura and secondary autoimmune thrombocytopenic purpura. | 2002 | Br. J. Haematol. | pmid:12139750 |
| Vicente R et al. | [Helicobacter pylori eradication in patients with peptic ulcer after two treatment failures: a prospective culture-guided study]. | Gastroenterol Hepatol | pmid:12139836 | |
| Tursi A et al. | Efficacy and tolerability of ranitidine bismuth citrate plus amoxycillin and clarithromycin as first- or second-line therapy to cure Helicobacter pylori infection. | 2002 Jul-Aug | Hepatogastroenterology | pmid:12143188 |
| Calvet X et al. | One-week triple vs. quadruple therapy for Helicobacter pylori infection - a randomized trial. | 2002 | Aliment. Pharmacol. Ther. | pmid:12144575 |
| Wallace MR | Risk factors for Helicobacter pylori resistance. | 2002 | Curr Gastroenterol Rep | pmid:12149170 |
| Blondeau JM | The evolution and role of macrolides in infectious diseases. | 2002 | Expert Opin Pharmacother | pmid:12150692 |
| Ushiama H et al. | Dose-dependent inhibition of CYP3A activity by clarithromycin during Helicobacter pylori eradication therapy assessed by changes in plasma lansoprazole levels and partial cortisol clearance to 6beta-hydroxycortisol. | 2002 | Clin. Pharmacol. Ther. | pmid:12152002 |
| Aubry A et al. | Sixty-three cases of Mycobacterium marinum infection: clinical features, treatment, and antibiotic susceptibility of causative isolates. | 2002 Aug 12-26 | Arch. Intern. Med. | pmid:12153378 |
| Endo H et al. | Localization of [14C]clarithromycin in rat gastric tissue when administered with lansoprazole and amoxicillin. | 2002 | J. Antimicrob. Chemother. | pmid:12161414 |
| Küçükgüzel SG and Rollas S | Synthesis, characterization of novel coupling products and 4-arylhydrazono-2-pyrazoline-5-ones as potential antimycobacterial agents. | 2002 | Farmaco | pmid:12164219 |
| Miwa H et al. | Improvement of reflux symptoms 3 years after cure of Helicobacter pylori infection: a case-controlled study in the Japanese population. | 2002 | Helicobacter | pmid:12165028 |
| Ishibashi S et al. | Normalization of phospholipids concentration of the gastric mucosa was observed in patients with peptic ulcer after eradication of Helicobacter pylori. | 2002 | Helicobacter | pmid:12165032 |
| Bettoni L et al. | Chronic urticaria induced by eradication therapy of Helicobacter pylori: a case report. | 2002 | Helicobacter | pmid:12165036 |
| Cuhadaroglu C et al. | Respiratory distress with acitretin, reversal by corticosteroid. | 2001 | Dermatol. Online J. | pmid:12165221 |
| Kaneko T et al. | [A case of rapid exacerbation of a pulmonary infection with Mycobacterium intracellulare in an immunocompetent pregnant woman]. | 2002 | Nihon Kokyuki Gakkai Zasshi | pmid:12166262 |
| Enomoto F et al. | Effect of new macrolides on the expression of adhesion molecules on neutrophils in chronic sinusitis. | 2002 | Auris Nasus Larynx | pmid:12167449 |
| Bayes M et al. | Gateways to Clinical Trials. June 2002. | 2002 | Methods Find Exp Clin Pharmacol | pmid:12168506 |
| Wolle K et al. | Antibiotic susceptibility of Helicobacter pylori in Germany: stable primary resistance from 1995 to 2000. | 2002 | J. Med. Microbiol. | pmid:12171304 |
| Labenz J et al. | Primary prevention of diclofenac associated ulcers and dyspepsia by omeprazole or triple therapy in Helicobacter pylori positive patients: a randomised, double blind, placebo controlled, clinical trial. | 2002 | Gut | pmid:12171952 |
| Johnson RC et al. | Disseminated Mycobacterium ulcerans disease in an HIV-positive patient: a case study. | 2002 | AIDS | pmid:12172103 |
| Boon YH et al. | One week regimen of esomeprazole based triple therapy is sufficient for duodenal ulcer healing and Helicobacter pylori eradication in patients with duodenal ulcer disease. | 2002 | Eur J Gastroenterol Hepatol | pmid:12172417 |
| Glupczynski Y et al. | Comparison of the E test and agar dilution method for antimicrobial suceptibility testing of Helicobacter pylori. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:12172749 |
| Al-Mobeireek AF | Rapidly growing mycobacterial pulmonary infection in association with severe gastroesophageal reflux disease. | 2002 | Saudi Med J | pmid:12174240 |
| Rivory LP et al. | Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response. | 2002 | Br. J. Cancer | pmid:12177794 |
| Rebora A | The management of rosacea. | 2002 | Am J Clin Dermatol | pmid:12180896 |
| Niazi S et al. | Atypical mycobacterial osteomyelitis in a non-AIDS patient. | 2002 | Conn Med | pmid:12181861 |
| Boixeda D et al. | Efficacy of quadruple therapy with pantoprazole, bismuth, tetracycline and metronidazole as rescue treatment for Helicobacter pylori infection. | 2002 | Aliment. Pharmacol. Ther. | pmid:12182745 |
| Clark C et al. | In vitro selection of resistance in Haemophilus influenzae by amoxicillin-clavulanate, cefpodoxime, cefprozil, azithromycin, and clarithromycin. | 2002 | Antimicrob. Agents Chemother. | pmid:12183253 |
| Watanabe T and Chiba T | [Clinical features of peptic ulcer disease in the elderly]. | 2002 | Nippon Rinsho | pmid:12187741 |
| Nakamura T and Terano A | [Eradication therapy of Helicobacter pylori for elderly patients in Japan]. | 2002 | Nippon Rinsho | pmid:12187752 |
| Iwabuchi H and Matsuzaki K | [The treatment of peptic ulcer in elderly CRF patients]. | 2002 | Nippon Rinsho | pmid:12187758 |
| Kurata Y et al. | Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein. | 2002 | Clin. Pharmacol. Ther. | pmid:12189368 |
| MorfÃn Maciel BM and Castillo Ramos HA | [Reactive polyarthritis and painful dermatographism caused by Helicobacter pylori]. | 2002 May-Jun | Rev Alerg Mex | pmid:12190006 |
| Bégué RE et al. | Effect of Helicobacter pylori eradication in the glycemia of children with type 1 diabetes: a preliminary study. | 2002 | South. Med. J. | pmid:12190218 |
| Tozuka Y et al. | Characterization and quantitation of clarithromycin polymorphs by powder X-ray diffractometry and solid-state NMR spectroscopy. | 2002 | Chem. Pharm. Bull. | pmid:12192153 |
| Bussing R and Gende A | Severe hypoglycemia from clarithromycin-sulfonylurea drug interaction. | 2002 | Diabetes Care | pmid:12196446 |
| Sheu BS et al. | Impact of supplement with Lactobacillus- and Bifidobacterium-containing yogurt on triple therapy for Helicobacter pylori eradication. | 2002 | Aliment. Pharmacol. Ther. | pmid:12197847 |
| Pilotto A and Salles N | Helicobacter pylori infection in geriatrics. | 2002 | Helicobacter | pmid:12197911 |
| Boyanova L et al. | The status of antimicrobial resistance of Helicobacter pylori in eastern Europe. | 2002 | Clin. Microbiol. Infect. | pmid:12199848 |
| Murcia J et al. | [Acute myocardial failure in a young man: Q-fever myocarditis]. | 2002 | Rev Esp Cardiol | pmid:12199986 |
| Vallejo Camazón N et al. | [Ventricular tachycardia and long QT associated with clarithromycin administration in a patient with HIV infection]. | 2002 | Rev Esp Cardiol | pmid:12199987 |
| Mak SK et al. | Efficacy of a 1-week course of proton-pump inhibitor-based triple therapy for eradicating Helicobacter pylori in patients with and without chronic renal failure. | 2002 | Am. J. Kidney Dis. | pmid:12200810 |
| Maizumi N et al. | Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts. | 2002 | J. Periodont. Res. | pmid:12200967 |
| Weber W et al. | Macrolide-based transgene control in mammalian cells and mice. | 2002 | Nat. Biotechnol. | pmid:12205509 |
| Henrion E et al. | [Severe multiorgan psittacosis in a 10-year-old boy]. | 2002 | Arch Pediatr | pmid:12205791 |
| Avery RK et al. | The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization. | 2002 | Bone Marrow Transplant. | pmid:12209353 |
| Kühler TC et al. | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 1. | 2002 | J. Med. Chem. | pmid:12213070 |
| Carcanague D et al. | Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 2. | 2002 | J. Med. Chem. | pmid:12213071 |
| Pilloni AP et al. | Antimicrobial action of Nitens mouthwash (cetyltrimethylammonium naproxenate) on multiple isolates of pharyngeal microbes: a controlled study against chlorhexidine, benzydamine, hexetidine, amoxicillin, amoxicillin-clavulanate, clarithromycin, and cefaclor. | 2002 | Chemotherapy | pmid:12218263 |
| Yan X et al. | Antibacterial effect of Kampo herbal formulation Hochu-ekki-to (Bu-Zhong-Yi-Qi-Tang) on Helicobacter pylori infection in mice. | 2002 | Microbiol. Immunol. | pmid:12222933 |
| Szlachcic A | The link between Helicobacter pylori infection and rosacea. | 2002 | J Eur Acad Dermatol Venereol | pmid:12224687 |
| Lamping DL et al. | The community-acquired pneumonia symptom questionnaire: a new, patient-based outcome measure to evaluate symptoms in patients with community-acquired pneumonia. | 2002 | Chest | pmid:12226033 |
| Bannwarth B et al. | Influence of Helicobacter pylori eradication therapy on the occurrence of gastrointestinal events in patients treated with conventional nonsteroidal antiinflammatory drugs combined with omeprazole. | 2002 | J. Rheumatol. | pmid:12233895 |
| Celik H and Ayar A | Clarithromycin inhibits myometrial contractions in isolated human myometrium independent of stimulus. | 2002 | Physiol Res | pmid:12234115 |
| Dega H et al. | Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice. | 2002 | Antimicrob. Agents Chemother. | pmid:12234844 |
| Endo H et al. | Effects of clarithromycin and amoxicillin on gastric emptying in rats. | 2002 | Antimicrob. Agents Chemother. | pmid:12234874 |
| Sherwood PV et al. | Impact of acid secretion, gastritis, and mucus thickness on gastric transfer of antibiotics in rats. | 2002 | Gut | pmid:12235069 |
| Milberg P et al. | Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12235254 |
| Gulten T et al. | The role of triple therapy, age, gender and smoking on the genotoxic effects of Helicobacter pylori infection. | 2002 Jul-Aug | J. Int. Med. Res. | pmid:12235919 |
| Nobata K et al. | Lower concentrations of clarithromycin suppress urease activity, motility, and binding to gastric epithelial cells in Helicobacter pylori isolates. | 2002 | Dig Liver Dis | pmid:12236482 |
| Felmingham D et al. | Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study, and compatative in vitro activity of the ketolide, telithromycin. | 2002 | J. Antimicrob. Chemother. | pmid:12239226 |
| Gruschke A et al. | [Osteomyelitis of the tibial head caused by Mycobacterium haemophilium in a patient with AIDS]. | 2002 | Dtsch. Med. Wochenschr. | pmid:12239654 |
| Fischbach W et al. | Minimal residual low-grade gastric MALT-type lymphoma after eradication of Helicobacter pylori. | 2002 | Lancet | pmid:12241663 |
| Davidson R and Péloquin L | Anti-inflammatory effects of the macrolides. | 2002 | J Otolaryngol | pmid:12243242 |
| Souza R et al. | Diffuse panbronchiolitis: an underdiagnosed disease? Study of 4 cases in Brazil. | 2002 Jul-Aug | Rev Hosp Clin Fac Med Sao Paulo | pmid:12244337 |
| Hurst M et al. | Levofloxacin: an updated review of its use in the treatment of bacterial infections. | 2002 | Drugs | pmid:12269858 |
| Koh WJ et al. | Nontuberculous mycobacterial pulmonary diseases in immunocompetent patients. | Korean J Radiol | pmid:12271159 | |
| Hisabe T et al. | Regression of CD5-positive and Helicobacter pylori-negative mucosa-associated lymphoid tissue lymphoma of the rectum after administration of antibiotics: report of a case. | 2002 | Dis. Colon Rectum | pmid:12352248 |
| Queiroz DM et al. | Factors associated with treatment failure of Helicobacter pylori infection in a developing country. | 2002 | J. Clin. Gastroenterol. | pmid:12352294 |
| Vasil'ev IuV and Kas'ianenko VI | [Seven-day antihelicobacter therapy of duodenal ulcer associated with Helicobacter pylori and prospects for treating patients]. | 2002 | Eksp Klin Gastroenterol | pmid:12353382 |
| Celis MR et al. | [Diagnostic methods and treatment of community-acquired pneumonia in Spain: NACE study]. | 2002 | Med Clin (Barc) | pmid:12356360 |
| Zapater P et al. | A prospective study of the clarithromycin-digoxin interaction in elderly patients. | 2002 | J. Antimicrob. Chemother. | pmid:12356809 |
| Kolkman W et al. | [Ototoxicity induced by clarithromycin]. | 2002 | Ned Tijdschr Geneeskd | pmid:12357877 |
| Boyanova L et al. | Prevalence of resistant Helicobacter pylori isolates in Bulgarian children. | 2002 | J. Med. Microbiol. | pmid:12358070 |
| Vasil'ev IuV et al. | [Fromilid (clarithromycin) in eradication patients in patients with duodenal ulcer associated with Helicobacter pylori (comparison of two treatment variations)]. | 2002 | Ter. Arkh. | pmid:12360599 |
| Tsutsumi K et al. | The effect of erythromycin and clarithromycin on the pharmacokinetics of intravenous digoxin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:12362931 |
| Vasil'ev IuV and Zvenigorodskaia LA | [Fromilide (clarithromycin) in eradication of Helicobacter pylori in patients with duodenal ulcer]. | 2002 | Antibiot. Khimioter. | pmid:12365323 |