| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
clarithromycin
clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.
Cross Reference
Introduction
To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with clarithromycin?
clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (63)
- J. Antimicrob. Chemother. (56)
- J. Clin. Microbiol. (39)
- Others (258)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with clarithromycin
PubChem Associated disorders and diseases
What pathways are associated with clarithromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with clarithromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- J. Antimicrob. Chemother. (25)
- Antimicrob. Agents Chemother. (20)
- J. Clin. Microbiol. (9)
- Others (66)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with clarithromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with clarithromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with clarithromycin?
Related references are published most in these journals:
- J. Antimicrob. Chemother. (20)
- Antimicrob. Agents Chemother. (17)
- J. Clin. Microbiol. (13)
- Others (57)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with clarithromycin?
Mouse Model
Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).
Knock-out
Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).
Experimental Pneumococcal Meningitis
Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (2)
- Clin. Infect. Dis. (1)
- FEMS Immunol. Med. Microbiol. (1)
- Others (2)
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with clarithromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sung JJ et al. | One-week use of ranitidine bismuth citrate, amoxycillin and clarithromycin for the treatment of Helicobacter pylori-related duodenal ulcer. | 1998 | Aliment. Pharmacol. Ther. | pmid:9726384 |
| Pazzi P et al. | Short-term low-dose pantoprazole-based triple therapy for cure of Helicobacter pylori infection in duodenal ulcer patients. | 1998 | Aliment. Pharmacol. Ther. | pmid:9726385 |
| Harris AW et al. | Incidence of duodenal ulcer healing after 1 week of proton pump inhibitor triple therapy for eradication of Helicobacter pylori. The Lansoprazole Helicobacter Study Group. | 1998 | Aliment. Pharmacol. Ther. | pmid:9726387 |
| Bayoumi AM and Redelmeier DA | Preventing Mycobacterium avium complex in patients who are using protease inhibitors: a cost-effectiveness analysis. | 1998 | AIDS | pmid:9727572 |
| Bermudez LE et al. | Clarithromycin significantly improves interleukin-12-mediated anti-Mycobacterium avium activity and abolishes toxicity in mice. | 1998 | J. Infect. Dis. | pmid:9728568 |
| Gorski JC et al. | The contribution of intestinal and hepatic CYP3A to the interaction between midazolam and clarithromycin. | 1998 | Clin. Pharmacol. Ther. | pmid:9728893 |
| Barzilai A et al. | Successful treatment of disseminated Mycobacterium simiae infection in AIDS patients. | 1998 | Scand. J. Infect. Dis. | pmid:9730300 |
| Graham DY et al. | Effect of H. pylori infection and CagA status on leukocyte counts and liver function tests: extra-gastric manifestations of H. pylori infection. | 1998 | Helicobacter | pmid:9731987 |
| Bazzoli F et al. | Efficacy of lansoprazole in eradicating Helicobacter pylori: a meta-analysis. | 1998 | Helicobacter | pmid:9731991 |
| Lanza FL et al. | Ranitidine bismuth citrate plus clarithromycin: a dual therapy regimen for patients with duodenal ulcer. | 1998 | Helicobacter | pmid:9731994 |
| Vakil N et al. | Clarithromycin-resistant Helicobacter pylori in patients with duodenal ulcer in the United States. | 1998 | Am. J. Gastroenterol. | pmid:9732920 |
| Chu KM et al. | A prospective randomized trial comparing the use of omeprazole-based dual and triple therapy for eradication of Helicobacter pylori. | 1998 | Am. J. Gastroenterol. | pmid:9732921 |
| Lamouliatte H et al. | Dual therapy using a double dose of lansoprazole with amoxicillin versus triple therapy using a double dose of lansoprazole, amoxicillin, and clarithromycin to eradicate Helicobacter pylori infection: results of a prospective randomized open study. | 1998 | Am. J. Gastroenterol. | pmid:9732938 |
| Alder JD et al. | Dynamics of clarithromycin and azithromycin efficacies against experimental Haemophilus influenzae pulmonary infection. | 1998 | Antimicrob. Agents Chemother. | pmid:9736568 |
| Siu LK et al. | Evaluation of a selective transport medium for gastric biopsy specimens to be cultured for Helicobacter pylori. | 1998 | J. Clin. Microbiol. | pmid:9738066 |
| Sevin E et al. | Co-detection of Helicobacter pylori and of its resistance to clarithromycin by PCR. | 1998 | FEMS Microbiol. Lett. | pmid:9742711 |
| Hiratsuka T et al. | [Severe bronchorrhea accompanying alveolar cell carcinoma: treatment with clarithromycin and inhaled beclomethasone]. | 1998 | Nihon Kokyuki Gakkai Zasshi | pmid:9742869 |
| Huang WH et al. | New one-week, low-dose triple therapy for the treatment of duodenal ulcer with Helicobacter pylori infection. | 1998 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:9745160 |
| Apseloff G et al. | Comparison of azithromycin and clarithromycin in their interactions with rifabutin in healthy volunteers. | 1998 | J Clin Pharmacol | pmid:9753212 |
| Gikas A et al. | In vitro susceptibility of Coxiella burnetii to trovafloxacin in comparison with susceptibilities to pefloxacin, ciprofloxacin, ofloxacin, doxycycline, and clarithromycin. | 1998 | Antimicrob. Agents Chemother. | pmid:9756789 |
| Debets-Ossenkopp YJ et al. | Explaining the bias in the 23S rRNA gene mutations associated with clarithromycin resistance in clinical isolates of Helicobacter pylori. | 1998 | Antimicrob. Agents Chemother. | pmid:9756790 |
| Greenblatt DJ et al. | Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences. | 1998 | Clin. Pharmacol. Ther. | pmid:9757151 |
| Denys A | [Theoretical basis for the antibiotic therapy of the upper part of the respiratory system]. | 1997 | Otolaryngol Pol | pmid:9757681 |
| Kubas G and Gospodarek T | [The use of clarithromycin and amoxycillin in pediatric acute otitis media]. | 1997 | Otolaryngol Pol | pmid:9757683 |
| Pontani D et al. | Susceptibility of European respiratory tract isolates to trovafloxacin, ciprofloxacin, clarithromycin, azithromycin and ampicillin. | 1998 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9758284 |
| Hawkey CJ et al. | Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study. Helicobacter Eradication for Lesion Prevention. | 1998 | Lancet | pmid:9759744 |
| Mégraud F and Doermann HP | Clinical relevance of resistant strains of Helicobacter pylori: a review of current data. | 1998 | Gut | pmid:9764043 |
| Heald AE et al. | Taste and smell complaints in HIV-infected patients. | 1998 | AIDS | pmid:9764787 |
| Horgen L et al. | Postantibiotic effect of amikacin, rifampin, sparfloxacin, clofazimine and clarithromycin against Mycobacterium avium. | 1997 | Res. Microbiol. | pmid:9765852 |
| Pipkin GA et al. | Review article: one-week clarithromycin triple therapy regimens for eradication of Helicobacter pylori. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768524 |
| Louw JA et al. | Helicobacter pylori eradication and ulcer healing with daily lansoprazole, plus 1 or 2 weeks co-therapy with amoxycillin and clarithromycin. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768531 |
| Laine L et al. | Low rate of emergence of clarithromycin-resistant Helicobacter pylori with amoxycillin co-therapy. | 1998 | Aliment. Pharmacol. Ther. | pmid:9768532 |
| Mukunda BN et al. | Clarithromycin therapy for bacillary peliosis did not prevent bacillary angiomatosis. | 1998 | Clin. Infect. Dis. | pmid:9770180 |
| Stack WA et al. | Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. | 1998 | Am. J. Gastroenterol. | pmid:9772054 |
| Adamek RJ and Bethke TD | Cure of Helicobacter pylori infection and healing of duodenal ulcer: comparison of pantoprazole-based one-week modified triple therapy versus two-week dual therapy. The International Pantoprazole HP Study Group. | 1998 | Am. J. Gastroenterol. | pmid:9772056 |
| Stolte M et al. | Cure of autoimmune gastritis by Helicobacter pylori eradication in a 21-year-old male. | 1998 | Z Gastroenterol | pmid:9773482 |
| Pina M et al. | Detection of point mutations associated with resistance of Helicobacter pylori to clarithromycin by hybridization in liquid phase. | 1998 | J. Clin. Microbiol. | pmid:9774580 |
| Griffith DE | Mycobacteria as pathogens of respiratory infection. | 1998 | Infect. Dis. Clin. North Am. | pmid:9779380 |
| Casswall TH et al. | One-week treatment with omeprazole, clarithromycin, and metronidazole in children with Helicobacter pylori infection. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9779970 |
| Aberg JA et al. | Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy. | 1998 | J. Infect. Dis. | pmid:9780266 |
| González Carro P et al. | [Efficacy of an ultrashort protocol in the eradication of Helicobacter pylori]. | 1998 | Rev Esp Enferm Dig | pmid:9780793 |
| Gangadharam PR | Clarithromycin for non-mycobacterial diseases? | 1998 | Int. J. Tuberc. Lung Dis. | pmid:9783536 |
| Hua J et al. | Characterization of clinical isolates of Helicobacter pylori in Singapore. | 1998 | Microbios | pmid:9785486 |
| Sádaba B et al. | Concurrent clarithromycin and cyclosporin A treatment. | 1998 | J. Antimicrob. Chemother. | pmid:9786481 |
| Finkenbine RD and Frye MD | Case of psychosis due to prednisone-clarithromycin interaction. | 1998 | Gen Hosp Psychiatry | pmid:9788033 |
| Borody TJ | Helicobacter pylori eradication failure--'salvage' therapies needed. | 1998 | Ital J Gastroenterol Hepatol | pmid:9789131 |
| Coudron PE and Stratton CW | The bactericidal activity of clarithromycin versus ampicillin alone and in combination with omeprazole and/or bismuth against clarithromycin-susceptible and clarithromycin-resistant strains of Helicobacter pylori. | 1998 | Diagn. Microbiol. Infect. Dis. | pmid:9791756 |
| Niang M et al. | [Painful nodular lesions]. | 1998 | Rev Med Interne | pmid:9793156 |
| Saika T et al. | [A mechanism of clarithromycin resistance in Helicobacter pylori]. | 1998 | Kansenshogaku Zasshi | pmid:9796191 |
| Langan C et al. | Short-course cefuroxime axetil therapy in the treatment of acute exacerbations of chronic bronchitis. | 1998 Jul-Aug | Int. J. Clin. Pract. | pmid:9796558 |