clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Calvet X et al. What is the optimal length of proton pump inhibitor-based triple therapies for H. pylori? A cost-effectiveness analysis. 2001 Aliment. Pharmacol. Ther. pmid:11421884
Nseir W et al. Randomised clinical trial: simvastatin as adjuvant therapy improves significantly the Helicobacter pylori eradication rate--a placebo-controlled study. 2012 Aliment. Pharmacol. Ther. pmid:22646167
Kamada T et al. The long-term effect of Helicobacter pylori eradication therapy on symptoms in dyspeptic patients with fundic atrophic gastritis. 2003 Aliment. Pharmacol. Ther. pmid:12869086
Murakami K et al. Efficacy of triple therapy comprising rabeprazole, amoxicillin and metronidazole for second-line Helicobacter pylori eradication in Japan, and the influence of metronidazole resistance. 2003 Aliment. Pharmacol. Ther. pmid:12492740
Gisbert JP et al. Seven-day 'rescue' therapy after Helicobacter pylori treatment failure: omeprazole, bismuth, tetracycline and metronidazole vs. ranitidine bismuth citrate, tetracycline and metronidazole. 1999 Aliment. Pharmacol. Ther. pmid:10540045
Khurana R et al. Meta-analysis: Helicobacter pylori eradication treatment efficacy in children. 2007 Aliment. Pharmacol. Ther. pmid:17305754
Georgopoulos SD et al. Effectiveness of two quadruple, tetracycline- or clarithromycin-containing, second-line, Helicobacter pylori eradication therapies. 2002 Aliment. Pharmacol. Ther. pmid:11876712
Elizalde JI et al. Influence of Helicobacter pylori infection and eradication on blood lipids and fibrinogen. 2002 Aliment. Pharmacol. Ther. pmid:11876713
Goddard AF et al. Randomized controlled comparison of nitroimidazoles for the eradication of Helicobacter pylori and relief of ulcer-associated and non-ulcer dyspepsia. 1999 Aliment. Pharmacol. Ther. pmid:10233187
Pilotto A et al. The effect of antibiotic resistance on the outcome of three 1-week triple therapies against Helicobacter pylori. 1999 Aliment. Pharmacol. Ther. pmid:10233191
Wong BC et al. Triple therapy with clarithromycin, omeprazole, and amoxicillin for eradication of Helicobacter pylori in duodenal ulcer patients in Asia and Africa. 2000 Aliment. Pharmacol. Ther. pmid:11069326
Vakil N et al. Patterns of gastritis and the effect of eradicating Helicobacter pylori on gastro-oesophageal reflux disease in Western patients with non-ulcer dyspepsia. 2006 Aliment. Pharmacol. Ther. pmid:16803603
Pilotto A and Malfertheiner P Review article: an approach to Helicobacter pylori infection in the elderly. 2002 Aliment. Pharmacol. Ther. pmid:11929385
Xiao SD et al. A multicentre study on eradication of Helicobacter pylori using four 1-week triple therapies in China. 2001 Aliment. Pharmacol. Ther. pmid:11136281
Mason JM et al. Helicobacter pylori eradication in long-term proton pump inhibitor users is highly cost-effective: economic analysis of the HELPUP trial. 2008 Aliment. Pharmacol. Ther. pmid:18793340
Armuzzi A et al. The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. 2001 Aliment. Pharmacol. Ther. pmid:11148433
Mégraud F and Lamouliatte H Review article: the treatment of refractory Helicobacter pylori infection. 2003 Aliment. Pharmacol. Ther. pmid:12786627
Savarino V et al. The impact of antibiotic resistance on the efficacy of three 7-day regimens against Helicobacter pylori. 2000 Aliment. Pharmacol. Ther. pmid:10886045
Drouet M et al. [Unusual clinical form of amoxicillin allergy]. 1996 Allerg Immunol (Paris) pmid:9011169
Can C et al. Symmetrical drug-related intertriginous and flexural exanthema induced by two different antibiotics. Allergol Immunopathol (Madr) pmid:23253684
Gangemi S et al. Immediate reaction to clarithromycin. 2001 Jan-Feb Allergol Immunopathol (Madr) pmid:11449533
Gaig P et al. Efficacy of the eradication of Helicobacter pylori infection in patients with chronic urticaria. A placebo-controlled double blind study. 2002 Sep-Oct Allergol Immunopathol (Madr) pmid:12396958
Karakaya G et al. Determining safe antibiotics for drug hypersensitive patients with the alternative method of double-triple test. Allergol Immunopathol (Madr) pmid:19080798
Malheiro D et al. Nimesulide-induced fixed drug eruption. 2005 Sep-Oct Allergol Immunopathol (Madr) pmid:16287549
Seitz CS et al. Suspicion of macrolide allergy after treatment of infectious diseases including Helicobacter pylori: results of allergological testing. Allergol Immunopathol (Madr) pmid:21269750
Moreira A et al. Is Helicobacter pylori infection associated with chronic idiopathic urticaria? Allergol Immunopathol (Madr) pmid:12890412
Brož P et al. Nonirritant intradermal skin test concentrations of ciprofloxacin, clarithromycin, and rifampicin. 2012 Allergy pmid:22435670
Igea JM and Lázaro M Hypersensitivity reaction to clarithromycin. 1998 Allergy pmid:9491242
Ben-Shoshan M et al. Anaphylactic reaction to clarithromycin in a child. 2009 Allergy pmid:19222423
Siddiqui S and Brightling CE Airways disease: phenotyping heterogeneity using measures of airway inflammation. 2007 Allergy Asthma Clin Immunol pmid:20525145
Xepapadaki P et al. Atypical bacteria and macrolides in asthma. 2008 Allergy Asthma Clin Immunol pmid:20525132
Desrosiers M et al. Canadian clinical practice guidelines for acute and chronic rhinosinusitis. 2011 Allergy Asthma Clin Immunol pmid:21310056
Wedi B et al. Urticaria and infections. 2009 Allergy Asthma Clin Immunol pmid:20066173
Thong BY Update on the management of antibiotic allergy. 2010 Allergy Asthma Immunol Res pmid:20358021
Park SJ et al. Fulminant and Fatal Multiple Organ Failure in a 12-Year-Old Boy With Mycoplasma pneumoniae Infection. 2012 Allergy Asthma Immunol Res pmid:22211173
Kim MH et al. A case of chlorpheniramine maleate-induced hypersensitivity with aspirin intolerance. 2011 Allergy Asthma Immunol Res pmid:21217928
Hong SJ The Role of Mycoplasma pneumoniae Infection in Asthma. 2012 Allergy Asthma Immunol Res pmid:22379599
Kariyawasam HH and Scadding GK Chronic rhinosinusitis: therapeutic efficacy of anti-inflammatory and antibiotic approaches. 2011 Allergy Asthma Immunol Res pmid:21966602
Damianos AJ and McGarrity TJ Treatment strategies for Helicobacter pylori infection. 1997 Am Fam Physician pmid:9191460
Karlstadt RG and Walker K Update on prescribing information for pantoprazole. 2003 Am Fam Physician pmid:12674447
Gregory DS Pertussis: a disease affecting all ages. 2006 Am Fam Physician pmid:16913160
Chaisson R Clarithromycin is effective against M. avium complex in AIDS. 1992 Am Fam Physician pmid:1456199
Elston D Nontuberculous mycobacterial skin infections: recognition and management. 2009 Am J Clin Dermatol pmid:19658440
Rebora A The management of rosacea. 2002 Am J Clin Dermatol pmid:12180896
Scheinfeld N Confluent and reticulated papillomatosis : a review of the literature. 2006 Am J Clin Dermatol pmid:17007541
Zeegelaar JE and Faber WR Imported tropical infectious ulcers in travelers. 2008 Am J Clin Dermatol pmid:18572973
Chang SL et al. Bilateral sporotrichoid lymphocutaneous dermatosis in a drug abuser: case report and review of the literature. 2008 Am J Clin Dermatol pmid:18973406
Wedi B and Kapp A Helicobacter pylori infection in skin diseases: a critical appraisal. 2002 Am J Clin Dermatol pmid:12010072
Curth HM et al. Effects of Helicobacter pylori Eradication in Chronic Spontaneous Urticaria: Results from a Retrospective Cohort Study. 2015 Am J Clin Dermatol pmid:26334425
Parsad D et al. A guide to selection and appropriate use of macrolides in skin infections. 2003 Am J Clin Dermatol pmid:12762831
Yeh I et al. Cutaneous mycobacterial spindle cell pseudotumor: a potential mimic of soft tissue neoplasms. 2011 Am J Dermatopathol pmid:21712686
Song H et al. Cutaneous nontuberculous mycobacterial infection: a clinicopathological study of 7 cases. 2009 Am J Dermatopathol pmid:19384062
Lai J et al. Epithelioid histiocytic infiltrate caused by Mycobacterium scrofulaceum infection: a potential mimic of various neoplastic entities. 2013 Am J Dermatopathol pmid:22935892
Sketris IS et al. Comparison of anti-infective drug use in elderly persons in Manitoba, Nova Scotia, and Saskatchewan, Canada: relationship to drug insurance reimbursement policies. 2004 Am J Geriatr Pharmacother pmid:15555476
Hsu O et al. Decreased plasma efavirenz concentrations in a patient receiving rifabutin. 2010 Am J Health Syst Pharm pmid:20852162
Johnson TJ and Hedge DD Esomeprazole: a clinical review. 2002 Am J Health Syst Pharm pmid:12132559
Halpern MT et al. Cost-effectiveness of gemifloxacin: results from the GLOBE study. 2002 Am J Health Syst Pharm pmid:12132563
Chahine C et al. Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori. 2001 Am J Health Syst Pharm pmid:11596697
Henneman A and Thornby KA Risk of hypotension with concomitant use of calcium-channel blockers and macrolide antibiotics. 2012 Am J Health Syst Pharm pmid:22644980
Kaeser YA et al. Severe hypotension and bradycardia associated with verapamil and clarithromycin. 1998 Am J Health Syst Pharm pmid:9825040
Three new studies expand understanding of MAC therapy. 1996 Am J Health Syst Pharm pmid:8899122
Peloquin CA and Berning SE Advice on treatment of Mycobacterium avium complex infection. 1997 Am J Health Syst Pharm pmid:9161632
H. pylori treatment recognized by FDA. 1996 Am J Health Syst Pharm pmid:8725200
Sonnenberg A et al. Antibiotic therapy of Helicobacter pylori infection reduces healthcare expenditures related to duodenal ulcer. 1999 Am J Manag Care pmid:10345967
Lilley LL and Guanci R A dangerous combination. 1998 Am J Nurs pmid:9612423
Antibiotic gets FDA nod for MAC treatment. 1994 Am J Nurs pmid:8304386
Evans AK and Cunningham MJ Atypical mycobacterial cervicofacial lymphadenitis in children: a disease as old as mankind, yet a persistent challenge. 2005 Sep-Oct Am J Otolaryngol pmid:16137534
Hashisaki GT Update on macrolide antibiotics. 1995 May-Jun Am J Otolaryngol pmid:7661309
Einarson A et al. A prospective controlled multicentre study of clarithromycin in pregnancy. 1998 Am J Perinatol pmid:9890248
Jacoby EB and Porter KB Helicobacter pylori infection and persistent hyperemesis gravidarum. 1999 Am J Perinatol pmid:10355915
Abouesh A and Hobbs WR Clarithromycin-induced mania. 1998 Am J Psychiatry pmid:9812131
Brooks JO and Hoblyn JC Secondary mania in older adults. 2005 Am J Psychiatry pmid:16263839
Keicho N and Kudoh S Diffuse panbronchiolitis: role of macrolides in therapy. 2002 Am J Respir Med pmid:14720066
Darkes MJ and Perry CM Clarithromycin extended-release tablet: a review of its use in the management of respiratory tract infections. 2003 Am J Respir Med pmid:14720016
Tohnai A et al. Clarithromycin suppresses proliferation of rat nasal epithelium exposed to endotoxin. 1998 Nov-Dec Am J Rhinol pmid:9883303
Zeng M et al. Comparison of efficacy of mometasone furoate versus clarithromycin in the treatment of chronic rhinosinusitis without nasal polyps in Chinese adults. 2011 Nov-Dec Am J Rhinol Allergy pmid:22185725
Gupta AK and Moorman CT Nocardia nova infection after primary anterior cruciate ligament reconstruction with tibialis anterior allograft. 2010 Am J Sports Med pmid:20375367
Yang X et al. Comparison Between Sequential Therapy and Modified Bismuth-Included Quadruple Therapy for Helicobacter pylori Eradication in Chinese Patients. Am J Ther pmid:25923229
Feng L et al. Sequential Therapy or Standard Triple Therapy for Helicobacter pylori Infection: An Updated Systematic Review. Am J Ther pmid:25569598
McCarthy DM et al. Impact of cotherapy with some proton pump inhibitors on medical claims among HMO patients already using other common drugs also cleared by cytochrome P450. 2003 Sep-Oct Am J Ther pmid:12975717
Chang NL et al. Clarithromycin-Induced Torsades de Pointes. Am J Ther pmid:25057773
Kurowski K et al. Clarithromycin-induced alterations in vaginal flora. 2000 Am J Ther pmid:11317173
Alkim H et al. Role of Bismuth in the Eradication of Helicobacter pylori. Am J Ther pmid:26808355
Jacobson TA Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors. 2004 Am. J. Cardiol. pmid:15518608
Hsu CH et al. The lesson of supplementary treatment with Chinese medicine on severe laboratory-confirmed SARS patients. 2006 Am. J. Chin. Med. pmid:17163582
Wang YC et al. In vitro activity of Impatiens balsamina L. against multiple antibiotic-resistant Helicobacter pylori. 2009 Am. J. Chin. Med. pmid:19655409
Sauter C and Blum S Regression of lung lesions in Hodgkin's disease by antibiotics: case report and hypothesis on the etiology of Hodgkin's disease. 2003 Am. J. Clin. Oncol. pmid:12576932
Kapadia M et al. Invasive Streptomyces infections: six cases and literature review. 2007 Am. J. Clin. Pathol. pmid:17369139
Buchanan Keller K and Lemberg L Torsade. 2008 Am. J. Crit. Care pmid:18158394
Savarino V et al. What is the meaning of ranitidine in successful triple-therapy against Helicobacter pylori infection? 1995 Am. J. Gastroenterol. pmid:8540537
Hansen JM et al. Effect of a community screening for Helicobacter pylori: a 5-Yr follow-up study. 2008 Am. J. Gastroenterol. pmid:18445098
Chiba N Omeprazole and clarithromycin with and without metronidazole for the eradication of Helicobacter pylori. 1996 Am. J. Gastroenterol. pmid:8855737
Scholte GH et al. Genotyping of Helicobacter pylori in paraffin-embedded gastric biopsy specimens: relation to histological parameters and effects on therapy. 2002 Am. J. Gastroenterol. pmid:12135019
de Boer WA et al. Optimal treatment of Helicobacter pylori with ranitidine bismuth citrate (RBC): a randomized comparison between two 7-day triple therapies and a 14-day dual therapy. 1998 Am. J. Gastroenterol. pmid:9672338
Calvet X et al. Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial. 2005 Am. J. Gastroenterol. pmid:16086704
Fuccio L et al. Can sequential therapy for Helicobacter pylori eradication overcome clarithromycin resistance?: Data still do not support conclusions. 2010 Am. J. Gastroenterol. pmid:20606668
van der Wouden EJ et al. One-week triple therapy with ranitidine bismuth citrate, clarithromycin and metronidazole versus two-week dual therapy with ranitidine bismuth citrate and clarithromycin for Helicobacter pylori infection: a randomized, clinical trial. 1998 Am. J. Gastroenterol. pmid:9707042
Laine L et al. Randomized comparison of ranitidine bismuth citrate-based triple therapies for Helicobacter pylori. 1997 Am. J. Gastroenterol. pmid:9399755
Srinivasan R and Minocha A Cure of Helicobacter pylori: a hidden curse? 1997 Am. J. Gastroenterol. pmid:9399784
Luther J et al. Empiric quadruple vs. triple therapy for primary treatment of Helicobacter pylori infection: Systematic review and meta-analysis of efficacy and tolerability. 2010 Am. J. Gastroenterol. pmid:19755966