clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

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Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Shafran SD Clarithromycin prophylaxis for disseminated Mycobacterium avium complex infection--efficacy and acquired resistance. 1998 Clin. Infect. Dis. pmid:9798038
Craft JC et al. Clarithromycin resistance and susceptibility patterns of Mycobacterium avium strains isolated during prophylaxis for disseminated infection in patients with AIDS. 1998 Clin. Infect. Dis. pmid:9798037
Chodosh S et al. Efficacy of oral ciprofloxacin vs. clarithromycin for treatment of acute bacterial exacerbations of chronic bronchitis. The Bronchitis Study Group. 1998 Clin. Infect. Dis. pmid:9798025
Ouellet D et al. Pharmacokinetic interaction between ritonavir and clarithromycin. 1998 Clin. Pharmacol. Ther. pmid:9797791
Horgen L et al. Pulsed-exposure and postantibiotic leukocyte enhancement effects of amikacin, clarithromycin, clofazimine, and rifampin against intracellular Mycobacterium avium. 1998 Antimicrob. Agents Chemother. pmid:9797242
Piccolomini R et al. Bacteriostatic and bactericidal in vitro activities of clarithromycin and erythromycin against periodontopathic Actinobacillus actinomycetemcomitans. 1998 Antimicrob. Agents Chemother. pmid:9797240
Langan C et al. Short-course cefuroxime axetil therapy in the treatment of acute exacerbations of chronic bronchitis. 1998 Jul-Aug Int. J. Clin. Pract. pmid:9796558
Saika T et al. [A mechanism of clarithromycin resistance in Helicobacter pylori]. 1998 Kansenshogaku Zasshi pmid:9796191
Niang M et al. [Painful nodular lesions]. 1998 Rev Med Interne pmid:9793156
Coudron PE and Stratton CW The bactericidal activity of clarithromycin versus ampicillin alone and in combination with omeprazole and/or bismuth against clarithromycin-susceptible and clarithromycin-resistant strains of Helicobacter pylori. 1998 Diagn. Microbiol. Infect. Dis. pmid:9791756
Borody TJ Helicobacter pylori eradication failure--'salvage' therapies needed. 1998 Ital J Gastroenterol Hepatol pmid:9789131
Finkenbine RD and Frye MD Case of psychosis due to prednisone-clarithromycin interaction. 1998 Gen Hosp Psychiatry pmid:9788033
Sádaba B et al. Concurrent clarithromycin and cyclosporin A treatment. 1998 J. Antimicrob. Chemother. pmid:9786481
Hua J et al. Characterization of clinical isolates of Helicobacter pylori in Singapore. 1998 Microbios pmid:9785486
Gangadharam PR Clarithromycin for non-mycobacterial diseases? 1998 Int. J. Tuberc. Lung Dis. pmid:9783536
González Carro P et al. [Efficacy of an ultrashort protocol in the eradication of Helicobacter pylori]. 1998 Rev Esp Enferm Dig pmid:9780793
Aberg JA et al. Eradication of AIDS-related disseminated mycobacterium avium complex infection after 12 months of antimycobacterial therapy combined with highly active antiretroviral therapy. 1998 J. Infect. Dis. pmid:9780266
Casswall TH et al. One-week treatment with omeprazole, clarithromycin, and metronidazole in children with Helicobacter pylori infection. 1998 J. Pediatr. Gastroenterol. Nutr. pmid:9779970
Griffith DE Mycobacteria as pathogens of respiratory infection. 1998 Infect. Dis. Clin. North Am. pmid:9779380
Pina M et al. Detection of point mutations associated with resistance of Helicobacter pylori to clarithromycin by hybridization in liquid phase. 1998 J. Clin. Microbiol. pmid:9774580