clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with clarithromycin

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Authors Title Published Journal PubMed Link
Castro-Silva AN et al. Cutaneous Mycobacterium haemophilum infection in a kidney transplant recipient after acupuncture treatment. 2011 Transpl Infect Dis pmid:20534038
Korres DS et al. Multifocal spinal and extra-spinal Mycobacterium chelonae osteomyelitis in a renal transplant recipient. 2007 Transpl Infect Dis pmid:17313477
Baluch A et al. Successful management of Mycobacterium haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient. 2017 Transpl Infect Dis pmid:27775824
den Broeder AA et al. Disseminated Mycobacterium gordonae infection in a renal transplant recipient. 2003 Transpl Infect Dis pmid:14617305
Kim JE et al. Synchronous infection with Mycobacterium chelonae and Paecilomyces in a heart transplant patient. 2011 Transpl Infect Dis pmid:20412536
Lyons J et al. An unusual lung mass post stem cell transplantation. 2014 Transpl Infect Dis pmid:24995624
de Jong JJ et al. Atypical mycobacterium infection with dermatological manifestation in a renal transplant recipient. 1999 Transpl. Int. pmid:10080410
Morales P et al. Successful recovery after disseminated infection due to mycobacterium abscessus in a lung transplant patient: subcutaneous nodule as first manifestation--a case report. 2007 Transplant. Proc. pmid:17889205
Sezer S et al. Association of helicobacter pylori infection with nutritional status in hemodialysis patients. 2004 Jan-Feb Transplant. Proc. pmid:15013297
Qvist T et al. First report of lung transplantation in a patient with active pulmonary Mycobacterium simiae infection. 2013 Transplant. Proc. pmid:23267789
Fujiwara T et al. Helicobacter pylori infection in renal transplant recipients. 2000 Transplant. Proc. pmid:11120026
Bhaloo S and Prasad GV Severe reduction in tacrolimus levels with rifampin despite multiple cytochrome P450 inhibitors: a case report. 2003 Transplant. Proc. pmid:14611983
Lasmar EP et al. Mucosa-associated lymphoid tissue gastric lymphoma regression in a renal transplant patient after conversion of the immunosuppression to sirolimus: a case report. 2009 Transplant. Proc. pmid:19376398
Freudenberger RS and Simafranca SM Cutaneous infection with rapidly-growing mycobacterial infection following heart transplant: a case report and review of the literature. 2006 Transplant. Proc. pmid:16797350
Ogawa M et al. Matrix metalloproteinase suppression induced by clarithromycin in murine cardiac allografts. 2009 Jan-Feb Transplant. Proc. pmid:19249565
Gómez G et al. Acute tacrolimus nephrotoxicity in renal transplant patients treated with clarithromycin. 1999 Transplant. Proc. pmid:10500563
Tokgöz B et al. Effects of azithromycin on cyclosporine-induced gingival hyperplasia in renal transplant patients. 2004 Transplant. Proc. pmid:15621128
Naik S et al. Successful treatment of Nocardia nova bacteremia and multilobar pneumonia with clarithromycin in a heart transplant patient. 2007 Transplant. Proc. pmid:17580232
Benden C and Boehler A Long-term clarithromycin therapy in the management of lung transplant recipients. 2009 Transplantation pmid:19461491
Ferrari SL et al. The interaction between clarithromycin and cyclosporine in kidney transplant recipients. 1994 Transplantation pmid:7940695
Torpiano P and Pace D Clinically-diagnosed Mediterranean Spotted Fever in Malta. Travel Med Infect Dis pmid:29462726
Swanson RN et al. Once-daily azithromycin for 3 days compared with clarithromycin for 10 days for acute exacerbation of chronic bronchitis: a multicenter, double-blind, randomized study. 2005 Treat Respir Med pmid:15725048
Banerjee D et al. The effect of oral clarithromycin on bronchial airway inflammation in moderate-to-severe stable COPD: a randomized controlled trial. 2004 Treat Respir Med pmid:15174894
Aukema AA and Fokkens WJ Chronic rhinosinusitis: management for optimal outcomes. 2004 Treat Respir Med pmid:15182211
Ambrose PG Antimicrobial susceptibility breakpoints: PK-PD and susceptibility breakpoints. 2005 Treat Respir Med pmid:15846151
McCormack PL and Keating GM Spotlight on amoxicillin/clavulanic acid 2000 mg/125 mg extended release (XR) in respiratory tract infections in adults. 2005 Treat Respir Med pmid:16137193
Böttger EC Resistance to drugs targeting protein synthesis in mycobacteria. 1994 Trends Microbiol. pmid:7850212
Montoya CJ et al. Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trial. 2009 Trials pmid:19538732
Lee H et al. Concomitant, sequential, and 7-day triple therapy in first-line treatment of Helicobacter pylori infection in Korea: study protocol for a randomized controlled trial. 2017 Trials pmid:29149904
Chang AB et al. Randomized placebo-controlled trial on azithromycin to reduce the morbidity of bronchiolitis in Indigenous Australian infants: rationale and protocol. 2011 Trials pmid:21492416
Neuhann HF et al. Efficacy of different antibiotic regimens for eradication treatment of Helicobacter pylori infection in peptic ulcer disease in Tanzanian patients. 2003 Trop Doct pmid:14620428
Amarapurkar D et al. Helicobacter pylori eradication: efficacy of conventional therapy in India. 2004 Trop Doct pmid:15117141
Aminian K et al. A randomized trial comparing four Helicobacter pylori eradication regimens: standard triple therapy, ciprofloxacin based triple therapy, quadruple and sequential therapy. 2010 Oct-Dec Trop Gastroenterol pmid:21568147
Lubell Y et al. Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. 2011 Trop. Med. Int. Health pmid:21740488
Ndip RN et al. Helicobacter pylori isolates recovered from gastric biopsies of patients with gastro-duodenal pathologies in Cameroon: current status of antibiogram. 2008 Trop. Med. Int. Health pmid:18384477
Jamal MA et al. Molecular basis of clarithromycin-resistance in Mycobacterium avium intracellulare complex. 2000 Tuber. Lung Dis. pmid:10897378
Lazard T et al. Chloroquine does not enhance the activity of clarithromycin against multiplication of Mycobacterium avium within human macrophages. 1994 Tuber. Lung Dis. pmid:7949074
Saito H et al. Therapeutic effect of KRM-1648 with various antimicrobials against Mycobacterium avium complex infection in mice. 1995 Tuber. Lung Dis. pmid:7718848
Sanchez T et al. Quantitation of mycobacteria in blood specimens from patients with AIDS. 1994 Tuber. Lung Dis. pmid:7841433
Heifets LB Clarithromycin against Mycobacterium avium complex infections. 1996 Tuber. Lung Dis. pmid:8733409
Falkinham JO et al. Antibacterial activities of dendritic amphiphiles against nontuberculous mycobacteria. 2012 Tuberculosis (Edinb) pmid:22209468
Clarithromycin. 2008 Tuberculosis (Edinb) pmid:18486039
Howard ST Recent progress towards understanding genetic variation in the Mycobacterium abscessus complex. 2013 Tuberculosis (Edinb) pmid:24388643
De Sanctis V et al. Anti-Helicobacter pylori therapy in primary MALT lymphoma of rectum. 2012 Jul-Aug Tumori pmid:23052174
Miyamoto S et al. Analysis of Helicobacter pylori genotypes in clinical gastric wash samples. 2016 Tumour Biol. pmid:26825980
Oikawa R et al. Enrichment of Helicobacter pylori mutant strains after eradication therapy analyzed by gastric wash-based quantitative pyrosequencing. 2017 Tumour Biol. pmid:28990461
Mrad SM et al. [Children Helicobacter pylori infection: antibiogram results]. 2005 Tunis Med pmid:16370209
Chelly I et al. [Gastric MALT lymphoma: anatomo-clinical data and outcome of early stage H. pylori-associated gastric MALT-lymphoma resistant to treatment]. 2011 Tunis Med pmid:22198892
Loghmari H et al. Clarithromycin versus metronidazole in first-line Helicobacter pylori eradication. Prospective randomized study of 85 Tunisian adults. 2012 Tunis Med pmid:22311445
Çekin AH et al. Use of probiotics as an adjuvant to sequential H. pylori eradication therapy: impact on eradication rates, treatment resistance, treatment-related side effects, and patient compliance. 2017 Turk J Gastroenterol pmid:28007678
AvÅŸar E et al. A multicenter, randomized, prospective study of 14-day ranitidine bismuth citrate- vs. lansoprazole-based triple therapy for the eradication of Helicobacter pylori in dyspeptic patients. 2013 Turk J Gastroenterol pmid:24254262
Ozdil B et al. Influence of CYP2C19 functional polymorphism on Helicobacter pylori eradication. 2010 Turk J Gastroenterol pmid:20533108
Özden A et al. Effectiveness of different treatment regimens in helicobacter pylori eradication: ten-year experience of a single institution. 2010 Turk J Gastroenterol pmid:20931423
YaÅŸar B et al. Efficacy of probiotics in Helicobacter pylori eradication therapy. 2010 Turk J Gastroenterol pmid:20931422
AltintaÅŸ E et al. Comparison of ranitidine bismuth citrate, tetracycline and metronidazole with ranitidine bismuth citrate and azithromycin for the eradication of Helicobacter pylori in patients resistant to PPI based triple therapy. 2004 Turk J Gastroenterol pmid:15334317
Sezgin O et al. Detection of point mutations on 23S rRNA of Helicobacter pylori and resistance to clarithromycin with PCR-RFLP in gastric biopsy specimens in Mersin, Turkey. 2008 Turk J Gastroenterol pmid:19115151
Tümgör G et al. Comparison of standard and standard plus vitamin E therapy for Helicobacter pylori eradications in children. 2014 Turk J Gastroenterol pmid:25910378
Çiftci İH et al. Comparison of FISH, RFLP and agar dilution methods for testing clarithromycin resistance of Helicobacter pylori. 2014 Turk J Gastroenterol pmid:25910373
Oztürk K et al. Diagnosis of helicobacter pylori infection. 2014 Turk J Gastroenterol pmid:25141328
Erçin CN et al. Comparison of 7- and 14-day first-line therapies including levofloxacin in patients with Helicobacter pylori positive non-ulcer dyspepsia. 2010 Turk J Gastroenterol pmid:20533106
Zhen-Hua Z et al. Characterization of 23S rRNA gene mutation in primary and secondary clarithromycin-resistant Helicobacter pylori strains from East China. 2013 Turk J Gastroenterol pmid:23794337
Baysal B et al. Effect of pantoprazole and Helicobacter pylori therapy on uninvestigated dyspeptic patients. 2015 Turk J Gastroenterol pmid:25698264
Uygun A et al. Recent success of pantoprazole -or lansoprazole- based clarithromycin plus amoxicillin treatment in the eradication of Helicobacter pylori. 2004 Turk J Gastroenterol pmid:16249974
Yakut M et al. Sequential therapy for Helicobacter pylori eradication. 2010 Turk J Gastroenterol pmid:20931421
Güliter S et al. Can lansoprazole, amoxicillin, and clarithromycin combination still be used as a first-line therapy for eradication of helicobacter pylori? 2005 Turk J Gastroenterol pmid:16252185
Cinar K et al. The effect of Helicobacter pylori eradication in patients with functional dyspepsia: assessment of different diagnostic tests. 2004 Turk J Gastroenterol pmid:15492914
Aydin A et al. The efficacy of two-week therapy with ranitidine bismuth citrate, amoxicillin and clarithromycin on Helicobacter pylori eradication in clarithromycinresistant and- sensitive cases. 2005 Turk J Gastroenterol pmid:16547848
AladaÄŸ M et al. Comparison of pantoprazole- vs. omeprazole- based triple therapy regimens in the treatment of Helicobacter pylori infection and duodenal ulcer healing in a Turkish population. 2005 Turk J Gastroenterol pmid:16547858
Sarkeshikian SS et al. Azithromycin based triple therapy versus standard clarithromycin based triple therapy in eradication of Helicobacter pylori infection in Iran: a randomized controlled clinical trial. 2013 Turk J Gastroenterol pmid:23794338
Sezgin O et al. Bismuth-based therapies for the first step eradication of Helicobacter pylori. 2006 Turk J Gastroenterol pmid:16830288
Demirci H et al. Influence of vitamin C and E supplementation on the eradication rates of triple and quadruple eradication regimens for Helicobacter pylori infection. 2015 Turk J Gastroenterol pmid:26510082
Bilgin M et al. Acute coronary syndrome secondary to clarithromycin: the first case and review of the literature. 2014 Turk Kardiyol Dern Ars pmid:25080953
DoÄŸru D et al. Long-term clarithromycin in cystic fibrosis: effects on inflammatory markers in BAL and clinical status. 2009 Sep-Oct Turk. J. Pediatr. pmid:20112595
Yildirim I et al. Comparison of the effect of benzathine penicillin G, clarithromycin, cefprozil and amoxicillin/clavulanate on the bacteriological response and throat flora in group A beta hemolytic streptococcal tonsillopharyngitis. 2008 Mar-Apr Turk. J. Pediatr. pmid:18664074
Tezer H et al. Mycoplasma pneumoniae-associated transverse myelitis with unexpected rapid response to macrolide therapy: a case report. 2008 Nov-Dec Turk. J. Pediatr. pmid:19227425
Çağan-Appak Y et al. Clarithromycin resistance and 23S rRNA gene point mutations of Helicobacter pylori infection in children. 2016 Turk. J. Pediatr. pmid:28276208
Schouenborg P [Clarithromycin]. 1996 Ugeskr. Laeg. pmid:8686028
Schmidt BJ and Hermansen MN [Late debut of neonatal pneumonia caused by Chlamydia trachomatis]. 2013 Ugeskr. Laeg. pmid:23428270
Petersen AM et al. [Resistance of Helicobacter pylori to clarithomycin]. 1998 Ugeskr. Laeg. pmid:9627511
Buch T and Andersen SE [Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval]. 2015 Ugeskr. Laeg. pmid:26471025
Velho PE et al. Severe anemia, panserositis, and cryptogenic hepatitis in an HIV patient infected with Bartonella henselae. 2007 Nov-Dec Ultrastruct Pathol pmid:18098054
Yoshida K et al. Chlamydia trachomatis infection in the semen of asymptomatic infertile men: detection of the antigen by in situ hybridization. 1994 Urol. Int. pmid:7855940
NeÄ­mark AI et al. [Efficacy of low-intensity laser radiation and antibacterial therapy in the treatment of chronic prostatitis in the presence of sexually transmitted infections]. 2007 May-Jun Urologiia pmid:17724830
Gao M et al. The effects of transrectal radiofrequency hyperthermia on patients with chronic prostatitis and the changes of MDA, NO, SOD, and Zn levels in pretreatment and posttreatment. 2012 Urology pmid:22100490
El-Garem Y et al. Seminal Helicobacter pylori treatment improves sperm motility in infertile asthenozoospermic men. 2014 Urology pmid:25432826
Lange JN et al. Sensitivity of human strains of Oxalobacter formigenes to commonly prescribed antibiotics. 2012 Urology pmid:22656407
Lee CK et al. Immunization with recombinant Helicobacter pylori urease decreases colonization levels following experimental infection of rhesus monkeys. 1999 Vaccine pmid:10195786
Rendi-Wagner P et al. National paediatric immunization program of high risk groups: no effect on the incidence of invasive pneumococcal diseases. 2009 Vaccine pmid:19393711
Robinson JG Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin. 2009 Vasc Health Risk Manag pmid:19436666
Kones R Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization. 2010 Vasc Health Risk Manag pmid:20859545
Bronander KA and Bloch MJ Potential role of the endocannabinoid receptor antagonist rimonabant in the management of cardiometabolic risk: a narrative review of available data. 2007 Vasc Health Risk Manag pmid:17580728
Wolbrette D et al. Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy. 2010 Vasc Health Risk Manag pmid:20730068
Falk JA et al. The emergence of oral tadalafil as a once-daily treatment for pulmonary arterial hypertension. 2010 Vasc Health Risk Manag pmid:20479949
Edmonds M The treatment of diabetic foot infections: focus on ertapenem. 2009 Vasc Health Risk Manag pmid:19997576
Laks T et al. Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center study: the DISCOVERY-Beta study. 2008 Vasc Health Risk Manag pmid:19337553
[Experience with treatment of chronic polypoid rhinosinusitis using low doses of clarithromycin in the postoperative period]. 2012 Vestn. Otorinolaringol. pmid:22678641
Bobacheva TIu [The treatment of chronic polypous rhinosinusitis in the postoperative period with low doses of clarithromycin]. 2012 Vestn. Otorinolaringol. pmid:23011378
Murai A et al. Mastitis caused by Mycobacterium kansasii infection in a dog. 2013 Vet Clin Pathol pmid:23808608
Hylton PK et al. Intracellular success: cytologic findings in an ulcerated submandibular mass from a cat. 2006 Vet Clin Pathol pmid:16967424
Dhama K et al. Tuberculosis in Birds: Insights into the Mycobacterium avium Infections. 2011 Vet Med Int pmid:21776352