clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

Cross Reference

Introduction

To understand associated biological information of clarithromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with clarithromycin?

clarithromycin is suspected in Infection, Helicobacter Pylori Infection, Pneumonia, Respiratory Tract Infections, PARKINSON DISEASE, LATE-ONSET, Community acquired pneumonia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with clarithromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 242

PubChem Associated disorders and diseases

What pathways are associated with clarithromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with clarithromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with clarithromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with clarithromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with clarithromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with clarithromycin?

Mouse Model

Mouse Model are used in the study 'Inflammation provoked by Mycoplasma pneumoniae extract: implications for combination treatment with clarithromycin and dexamethasone.' (Hirao S et al., 2011), Mouse Model are used in the study 'Tolerance and pharmacokinetic interactions of rifabutin and clarithromycin in human immunodeficiency virus-infected volunteers.' (Hafner R et al., 1998), Mouse Model are used in the study 'Clarithromycin attenuates mastectomy-induced acute inflammatory response.' (Chow LW et al., 2000) and Mouse Model are used in the study 'In vitro and in vivo influence of adjunct clarithromycin on the treatment of mucoid Pseudomonas aeruginosa.' (Bui KQ et al., 2000).

Knock-out

Knock-out are used in the study 'Intrinsic macrolide resistance in Mycobacterium smegmatis is conferred by a novel erm gene, erm(38).' (Nash KA, 2003).

Experimental Pneumococcal Meningitis

Experimental Pneumococcal Meningitis are used in the study 'Failure of treatment for chronic Mycobacterium abscessus meningitis despite adequate clarithromycin levels in cerebrospinal fluid.' (Maniu CV et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with clarithromycin

Download all related citations
Per page 10 20 50 100 | Total 7636
Authors Title Published Journal PubMed Link
Couturier J et al. Steroid-induced mania in an adolescent: risk factors and management. 2001 Can J Clin Pharmacol pmid:11493940
Cicconi V et al. Disappearance of antiphospholipid antibodies syndrome after Helicobacter pylori eradication. 2001 Am. J. Med. pmid:11501549
Kanamaru T et al. In vitro and in vivo antibacterial activities of TAK-083, an agent for treatment of Helicobacter pylori infection. 2001 Antimicrob. Agents Chemother. pmid:11502514
Chu HW et al. Evaluation of blood vessels and edema in the airways of asthma patients: regulation with clarithromycin treatment. 2001 Chest pmid:11502638
Holmberg SD and Moorman AC Possible bias of ascertainment in assessing chemoprophylaxis for cryptosporidiosis. 2001 AIDS pmid:11504998
Avcu N et al. The relationship between gastric-oral Helicobacter pylori and oral hygiene in patients with vitamin B12-deficiency anemia. 2001 Oral Surg Oral Med Oral Pathol Oral Radiol Endod pmid:11505263
González C et al. [In vitro antimicrobial susceptibility of Helicobacter pylori strains: isolation of strains resistant to clarithromycin]. 2001 Rev Med Chil pmid:11510204
Andersson T et al. Drug interaction studies with esomeprazole, the (S)-isomer of omeprazole. 2001 Clin Pharmacokinet pmid:11510629
Azuma T et al. Gastric leptin and Helicobacter pylori infection. 2001 Gut pmid:11511551
Martinot JB et al. A comparative study of clarithromycin modified release and amoxicillin/clavulanic acid in the treatment of acute exacerbation of chronic bronchitis. 2001 Jan-Feb Adv Ther pmid:11512528
Froehlich F et al. Helicobacter pylori eradication treatment does not benefit patients with nonulcer dyspepsia. 2001 Am. J. Gastroenterol. pmid:11513170
Maconi G et al. Prolonging proton pump inhibitor-based anti-Helicobacter pylori treatment from one to two weeks in duodenal ulcer: is it worthwhile? 2000 Dig Liver Dis pmid:11515622
Kim YG et al. Bioequivalence of clarithromycin tablet formulations assessed in Korean males. 2001 Int J Clin Pharmacol Ther pmid:11515711
Sazhin VP and Fedorov AV [Current principles of the use of laparoscopic surgery in gastroduodenal ulcer]. 2001 Khirurgiia (Mosk) pmid:11517693
Maev IV et al. [Experience in the use of losek (omeprazole) in gastroenterology]. 2001 Ter. Arkh. pmid:11523419
Douthwaite S Structure-activity relationships of ketolides vs. macrolides. 2001 Clin. Microbiol. Infect. pmid:11523556
Wongkusoltham P et al. Eradication rates of Helicobacter pylori between metronidazole-sensitive and metronidazole-resistant strains with metronidazole containing regimen in Thai patients with peptic ulcer disease. 2001 J Med Assoc Thai pmid:11529378
Schlegel L et al. In vitro activity of midecamycin diacetate, a 16-membered macrolide, against Streptococcus pyogenes isolated in France, 1995-1999. 2001 Clin. Microbiol. Infect. pmid:11531981
Miyashita N et al. In vitro activity of telithromycin, a new ketolide, against Chlamydia pneumoniae. 2001 J. Antimicrob. Chemother. pmid:11533006
Weiss K et al. In vitro activity of a novel ketolide ABT-773 against invasive strains of Streptococcus pneumoniae. 2001 J. Antimicrob. Chemother. pmid:11533007
Miyazaki S et al. Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. 2001 J. Antimicrob. Chemother. pmid:11533011
Bujanda L et al. [Comparative study of the eradication of Helicobacter pylori: ranitidine bismuth citrate versus omeprazole plus two antibiotics for seven days]. 2001 An Med Interna pmid:11534420
Naqvi B et al. Efficacy of clarithromycin in preventing viridans streptococcal bacteremia following autologous stem cell transplantation. 2001 Infection pmid:11545480
Beales IL Efficacy of Helicobacter pylori eradication therapies: a single centre observational study. 2001 BMC Gastroenterol pmid:11545677
Bharani A and Kumar H Drug points: Diabetes inspidus induced by ofloxacin. 2001 BMJ pmid:11546701
Fichtenbaum CJ et al. Reply to 'Possible bias of ascertainment in assessing chemoprophylaxis for cryptosporidiosis' by Holmberg and Moorman. 2001 AIDS pmid:11546956
Yamanaka Y et al. Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides. 2001 Biochem. Biophys. Res. Commun. pmid:11549274
Acar JF A comparison of side effects of levofloxacin to other agents concerning the ecological and microbiological effects on normal human flora. 2001 Chemotherapy pmid:11549785
Gisbert JP and Pajares JM Helicobacter pylori therapy: first-line options and rescue regimen. 2001 Dig Dis pmid:11549823
Magaret N et al. A randomized trial of lansoprazole, amoxycillin, and clarithromycin versus lansoprazole, bismuth, metronidazole and tetracycline in the retreatment of patients failing initial Helicobacter pylori therapy. 2001 Dig Dis pmid:11549829
Di Vita G et al. Resolution of Ménétrier's disease after Helicobacter pylori eradicating therapy. 2001 Dig Dis pmid:11549830
Müller H et al. Healing of active, non-atrophic autoimmune gastritis by H. pylori eradication. 2001 Digestion pmid:11549834
Bühling A et al. Influence of anti-Helicobacter triple-therapy with metronidazole, omeprazole and clarithromycin on intestinal microflora. 2001 Aliment. Pharmacol. Ther. pmid:11552917
Hokari K et al. Efficacy of triple therapy with rabeprazole for Helicobacter pylori infection and CYP2C19 genetic polymorphism. 2001 Aliment. Pharmacol. Ther. pmid:11552922
Kamberoglou D et al. Comparison of 1-week vs. 2- or 4-week therapy regimens with ranitidine bismuth citrate plus two antibiotics for Helicobacter pylori eradication. 2001 Aliment. Pharmacol. Ther. pmid:11552924
Hayashi T et al. Enhancement of innate immunity against Mycobacterium avium infection by immunostimulatory DNA is mediated by indoleamine 2,3-dioxygenase. 2001 Infect. Immun. pmid:11553555
Kroegel C et al. Chlamydia pneumoniae, clarithromycin, and severe asthma. 2001 Chest pmid:11555549
Nishimoto A et al. Studies on macrolide antibiotics I. Synthesis and antibacterial activity of erythromycin A 9-O-substituted oxime ether derivatives against Mycobacterium avium complex. 2001 Chem. Pharm. Bull. pmid:11558597
Scott LJ et al. Cefuroxime axetil: an updated review of its use in the management of bacterial infections. 2001 Drugs pmid:11558834
Yang JC et al. A multicenter study on eradication of Helicobacter pylori infection in patients with duodenal ulcer by lansoprazole-antibiotics combined therapy. 1999 J Microbiol Immunol Infect pmid:11561564
Kume K et al. Disappearance of both MALT lymphoma and hyperplastic polyps in the stomach after eradication of Helicobacter pylori. 2001 Am. J. Gastroenterol. pmid:11569719
Chey WD and Fendrick AM Noninvasive Helicobacter pylori testing for the "test-and-treat" strategy: a decision analysis to assess the effect of past infection on test choice. 2001 Arch. Intern. Med. pmid:11570943
Amsden GW Advanced-generation macrolides: tissue-directed antibiotics. 2001 Int. J. Antimicrob. Agents pmid:11574189
Rubinstein E Comparative safety of the different macrolides. 2001 Int. J. Antimicrob. Agents pmid:11574199
Fukushima K et al. [A case of post-tuberculosis chronic empyema with effective low-dose, long-term clarithromycin administration]. 2001 Nihon Kokyuki Gakkai Zasshi pmid:11579526
Ikeue T et al. [Pneumonia caused by Nocardia nova]. 2001 Nihon Kokyuki Gakkai Zasshi pmid:11579529
Kerr JR and Preston NW Current pharmacotherapy of pertussis. 2001 Expert Opin Pharmacother pmid:11584995
Tse KC et al. Delusion of worm infestation associated with clarithromycin in a patient on peritoneal dialysis. 2001 Jul-Aug Perit Dial Int pmid:11587409
Sillakivi T et al. An attempt at Helicobacter pylori eradication with intravenous clarithromycin in perforated peptic ulcer patients. 2001 Scand. J. Gastroenterol. pmid:11589389
Okazaki N et al. Characteristics of macrolide-resistant Mycoplasma pneumoniae strains isolated from patients and induced with erythromycin in vitro. 2001 Microbiol. Immunol. pmid:11592636
Yakoob J et al. Antibiotic susceptibility of Helicobacter pylori in the Chinese population. 2001 J. Gastroenterol. Hepatol. pmid:11595061
Keto Y et al. Gastric mucosal changes induced by long term infection with Helicobacter pylori in Mongolian gerbils: effects of bacteria eradication. 2001 Jan-Dec J. Physiol. Paris pmid:11595471
Buzás GM et al. Six regimens for the eradication of Helicobacter pylori (Hp) in duodenal ulcer patients: three consecutive trials (1995-1999). J. Physiol. Paris pmid:11595472
Chahine C et al. Ultrashort regimen of lansoprazole-amoxicillin-azithromycin for eradicating Helicobacter pylori. 2001 Am J Health Syst Pharm pmid:11596697
Agro K et al. Cost effectiveness in Canada of a multidrug prepackaged regimen (Hp-PAC)+ for Helicobacter pylori eradication. 2001 Pharmacoeconomics pmid:11596835
Hyde TB et al. Macrolide resistance among invasive Streptococcus pneumoniae isolates. 2001 JAMA pmid:11597287
Ling KL et al. Efficacy of a nitroimidazole containing tripletherapy regime in Singapore. 2001 Singapore Med J pmid:11599627
Lounis N et al. Efficacies of clarithromycin regimens against Mycobacterium xenopi in mice. 2001 Antimicrob. Agents Chemother. pmid:11600387
Nagai K et al. Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S. pyogenes. 2001 Antimicrob. Agents Chemother. pmid:11600391
Gikas A et al. In vitro susceptibility of Coxiella burnetii to linezolid in comparison with its susceptibilities to quinolones, doxycycline, and clarithromycin. 2001 Antimicrob. Agents Chemother. pmid:11600400
Bigard MA [Helicobacter pylori eradication. Therapeutic evolution, value of complementary studies]. 2001 Presse Med pmid:11603094
Tankovic J et al. Clarithromycin resistance of Helicobacter pylori has a major impact on the efficacy of the omeprazole-amoxicillin-clarithromycin therapy. 2001 Pathol. Biol. pmid:11642014
Timm S et al. First successful treatment of a primary high-grade gastric MALT lymphoma by eradication therapy for Helicobacter pylori. 2001 Gastroenterology pmid:11665693
Saruç M et al. The effect of CagA status on response to Helicobacter pylori eradication therapy in Western Turkey. 2001 Braz. J. Med. Biol. Res. pmid:11668353
Kumar D et al. Randomized trial of a quadruple-drug regimen and a triple-drug regimen for eradication of Helicobacter pylori: long-term follow-up study. 2001 Sep-Oct Indian J Gastroenterol pmid:11676331
Moayyedi P et al. Helicobacter pylori eradication does not exacerbate reflux symptoms in gastroesophageal reflux disease. 2001 Gastroenterology pmid:11677204
Schlünzen F et al. Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. 2001 Nature pmid:11677599
Gisbert JP et al. Are twelve days of omeprazole, amoxicillin and clarithromycin better than six days for treating H. pylori infection in peptic ulcer and in non-ulcer dyspepsia? 2001 Sep-Oct Hepatogastroenterology pmid:11677970
Xu H and Rashkow A Clarithromycin-induced digoxin toxicity: a case report and a review of the literature. 2001 Conn Med pmid:11678058
Kanj SS et al. Campylobacter fetus pericarditis in a patient with beta-thalassemia: case report and review of the literature. 2001 Clin. Microbiol. Infect. pmid:11678937
Lascols C et al. Effect of pH on the susceptibility of Helicobacter pylori to the ketolide telithromycin (HMR 3647) and clarithromycin. 2001 J. Antimicrob. Chemother. pmid:11679568
Guyot A and Barrett SP What is an appropriate control group to identify risk factors for Clostridium difficile-associated diarrhoea? 2001 J. Antimicrob. Chemother. pmid:11679574
Keto Y et al. [Pharmacological study on the pathological changes of the gastric mucosa in Helicobacter pylori-infected Mongolian gerbils]. 2001 Nippon Yakurigaku Zasshi pmid:11680169
Rüssmann H et al. Rapid and accurate determination of genotypic clarithromycin resistance in cultured Helicobacter pylori by fluorescent in situ hybridization. 2001 J. Clin. Microbiol. pmid:11682543
Ikeda S et al. Evaluation of the cost-effectiveness of Helicobacter pylori eradication triple therapy vs. conventional therapy for ulcers in Japan. 2001 Aliment. Pharmacol. Ther. pmid:11683692
Laurent J et al. A randomized comparison of four omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia. 2001 Aliment. Pharmacol. Ther. pmid:11683693
Asaka M et al. Guidelines in the management of Helicobacter pylori infection in Japan. 2001 Helicobacter pmid:11683920
Ozen H et al. Helicobacter pylori infection and recurrent abdominal pain in Turkish children. 2001 Helicobacter pmid:11683926
McNulty CA et al. A pilot study to determine the effectiveness of garlic oil capsules in the treatment of dyspeptic patients with Helicobacter pylori. 2001 Helicobacter pmid:11683929
Asaka M et al. A multicenter, double-blind study on triple therapy with lansoprazole, amoxicillin and clarithromycin for eradication of Helicobacter pylori in Japanese peptic ulcer patients. 2001 Helicobacter pmid:11683930
McCarty JM and Pierce PF Five days of cefprozil versus 10 days of clarithromycin in the treatment of an acute exacerbation of chronic bronchitis. 2001 Ann. Allergy Asthma Immunol. pmid:11686426
Dubois J and St-Pierre C In vitro susceptibility study of BMS-284756 against Legionella species. 2001 Sep-Oct Diagn. Microbiol. Infect. Dis. pmid:11687318
Vichev E et al. [Gastroduodenitis and ulcers--statistical study for 1998]. 2000 Vutr Boles pmid:11688321
Stratchounski LS et al. Antimicrobial susceptibility of nasopharyngeal isolates of Haemophilus influenzae from healthy children in day-care centres: results of multicentre study in Russia. 2001 Int. J. Antimicrob. Agents pmid:11691567
Zheng X et al. Clinical isolates of Streptococcus pneumoniae resistant to levofloxacin contain mutations in both gyrA and parC genes. 2001 Int. J. Antimicrob. Agents pmid:11691571
Dzierzanowska-Fangrat K et al. Primary resistance to clarithromycin in clinical strains of Helicobacter pylori isolated from children in Poland. 2001 Int. J. Antimicrob. Agents pmid:11691574
Dandekar SS and Laidlaw DA Suprachoroidal haemorrhage after addition of clarithromycin to warfarin. 2001 J R Soc Med pmid:11691898
Gisbert JP et al. Helicobacter pylori eradication therapy is more effective in peptic ulcer than in non-ulcer dyspepsia. 2001 Eur J Gastroenterol Hepatol pmid:11692055
Mayr-Kanhäuser S et al. Resolution of granulomatous rosacea after eradication of Helicobacter pylori with clarithromycin, metronidazole and pantoprazole. 2001 Eur J Gastroenterol Hepatol pmid:11692067
Horsburgh CR et al. Disseminated Mycobacterium avium complex disease among patients infected with human immunodeficiency virus, 1985-2000. 2001 Clin. Infect. Dis. pmid:11692307
Heurtin C et al. [Comparative study of the bacteriostatic and bactericidal activity of levofloxacin against Pasteurella strains isolated from man]. 2001 Pathol. Biol. pmid:11692747
Matheson AJ and Jarvis B Lansoprazole: an update of its place in the management of acid-related disorders. 2001 Drugs pmid:11693467
Chai D et al. [Effect of macrolides on biofilm of mucoid Pseudomonas aeruginosa]. 2001 Zhonghua Yi Xue Za Zhi pmid:11702671
Ena P et al. Rapid identification of cutaneous infections by nontubercular mycobacteria by polymerase chain reaction-restriction analysis length polymorphism of the hsp65 gene. 2001 Int. J. Dermatol. pmid:11703519
Carabias ML et al. [Are the antimicrobials used in community-acquired respiratory infection useful for preventing transmission of meningococcal disease? In vitro study]. 2001 Rev Esp Quimioter pmid:11704772
Okano A et al. Subcutaneous infection with Mycobacterium fortuitum after allogeneic bone marrow transplantation. 2001 Bone Marrow Transplant. pmid:11704796
Capitano B et al. Antibacterials for the prophylaxis and treatment of bacterial endocarditis in children. 2001 Paediatr Drugs pmid:11706922
Ramón Maestre J et al. [Bacteremia caused by Campylobacter jejuni in a 22 year old male with autoimmune haemolytic anaemia]. 2001 Enferm. Infecc. Microbiol. Clin. pmid:11709134
Komori T et al. Up-regulation by clarithromycin of alpha(1)-acid glycoprotein expression in liver and primary cultured hepatocytes. 2001 Biochem. Pharmacol. pmid:11709199
Endo H et al. Effects of lansoprazole and amoxicillin on uptake of [(14)C]clarithromycin into gastric tissue in rats. 2001 Antimicrob. Agents Chemother. pmid:11709323