Avermectin is a lipid of Polyketides (PK) class. Avermectin is associated with abnormalities such as Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease and Onchocerciasis. The involved functions are known as Anabolism, Binding (Molecular Function), physiological aspects, Saturated and Cell Growth. Avermectin often locates in receptor complex and cell body (neuron). The associated genes with Avermectin are Homologous Gene, Genome, Gene Clusters and Structural gene.
To understand associated biological information of Avermectin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Avermectin is suspected in Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease, Onchocerciasis, Filarial Elephantiases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Avermectin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Oesophagostomiasis | D009814 | 2 associated lipids |
| Arteritis | D001167 | 2 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Filariasis | D005368 | 6 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rath S et al. | Sorption behaviors of antimicrobial and antiparasitic veterinary drugs on subtropical soils. | 2019 | Chemosphere | pmid:30261417 |
| Sung YF et al. | Avermectin intoxication with coma, myoclonus, and polyneuropathy. | 2009 | Clin Toxicol (Phila) | pmid:19640241 |
| Guan HN et al. | Novel photodegradable insecticide W/TiO(2)/Avermectin nanocomposites obtained by polyelectrolytes assembly. | 2011 | Colloids Surf B Biointerfaces | pmid:21131183 |
| Yan Y et al. | Utilization of environmental waste cyanobacteria as a pesticide carrier: studies on controlled release and photostability of avermectin. | 2013 | Colloids Surf B Biointerfaces | pmid:23006573 |
| Campbell WC | History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents. | 2012 | Curr Pharm Biotechnol | pmid:22039784 |
| Danaher M et al. | Recent developments in the analysis of avermectin and milbemycin residues in food safety and the environment. | 2012 | Curr Pharm Biotechnol | pmid:22039790 |
| Horsberg TE | Avermectin use in aquaculture. | 2012 | Curr Pharm Biotechnol | pmid:22039799 |
| Rajkarnikar A et al. | Catalytic domain of AfsKav modulates both secondary metabolism and morphologic differentiation in Streptomyces avermitilis ATCC 31272. | 2006 | Curr. Microbiol. | pmid:16874544 |
| Gao Q et al. | Learn from microbial intelligence for avermectins overproduction. | 2017 | Curr. Opin. Biotechnol. | pmid:29049952 |
| Molinari G et al. | New ventures in the genotoxic and cytotoxic effects of macrocyclic lactones, abamectin and ivermectin. | 2010 | Cytogenet. Genome Res. | pmid:20389039 |