Avermectin is a lipid of Polyketides (PK) class. Avermectin is associated with abnormalities such as Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease and Onchocerciasis. The involved functions are known as Anabolism, Binding (Molecular Function), physiological aspects, Saturated and Cell Growth. Avermectin often locates in receptor complex and cell body (neuron). The associated genes with Avermectin are Homologous Gene, Genome, Gene Clusters and Structural gene.
To understand associated biological information of Avermectin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Avermectin is suspected in Parasitic infection, Parasitic Diseases, Scabies, Tropical Disease, Onchocerciasis, Filarial Elephantiases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Avermectin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arteritis | D001167 | 2 associated lipids |
| Oesophagostomiasis | D009814 | 2 associated lipids |
| Trichostrongylosis | D014253 | 5 associated lipids |
| Filariasis | D005368 | 6 associated lipids |
| Tuberculosis, Multidrug-Resistant | D018088 | 6 associated lipids |
| Trichostrongyloidiasis | D014252 | 7 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Jia X et al. | Adhesive polydopamine coated avermectin microcapsules for prolonging foliar pesticide retention. | 2014 | ACS Appl Mater Interfaces | pmid:25390545 |
| Wang F et al. | Structural and functional analysis of the loading acyltransferase from avermectin modular polyketide synthase. | 2015 | ACS Chem. Biol. | pmid:25581064 |
| Komatsu M et al. | Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites. | 2013 | ACS Synth Biol | pmid:23654282 |
| Todd KS et al. | Anthelmintic efficacy of avermectin B1a and dihydroavermectin B1a against ovine gastrointestinal nematodes in 1977. | 1984 | Am. J. Vet. Res. | pmid:6547280 |
| Wescott RB et al. | Efficacy of avermectin B1a for treatment of experimentally induced nematode infections in cattle. | 1980 | Am. J. Vet. Res. | pmid:6449894 |
| Florez DHÂ et al. | Pipette-tip solid-phase extraction using polypyrrole as efficient adsorbent for extraction of avermectins and milbemycins in milk. | 2018 | Anal Bioanal Chem | pmid:29607449 |
| Schaeffer JM et al. | A chemiluminescent assay for measuring avermectin binding sites. | 1989 | Anal. Biochem. | pmid:2729548 |
| Tom LA and Foster N | Development of a molecularly imprinted polymer for the analysis of avermectin. | 2010 | Anal. Chim. Acta | pmid:20969995 |
| Berendsen BJ et al. | The derivatisation of avermectins and milbemycins in milk: new insights and improvement of the procedure. | 2007 | Anal. Chim. Acta | pmid:17386656 |